DE69730314T2 - Dosierungsform von ibuprofen - Google Patents

Dosierungsform von ibuprofen Download PDF

Info

Publication number
DE69730314T2
DE69730314T2 DE69730314T DE69730314T DE69730314T2 DE 69730314 T2 DE69730314 T2 DE 69730314T2 DE 69730314 T DE69730314 T DE 69730314T DE 69730314 T DE69730314 T DE 69730314T DE 69730314 T2 DE69730314 T2 DE 69730314T2
Authority
DE
Germany
Prior art keywords
dosage form
ibuprofen
weight
bicarbonate
component
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69730314T
Other languages
German (de)
English (en)
Other versions
DE69730314D1 (de
Inventor
Ashley Ian PRICE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Reckitt Benckiser Healthcare UK Ltd
Original Assignee
Boots Co PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co PLC filed Critical Boots Co PLC
Publication of DE69730314D1 publication Critical patent/DE69730314D1/de
Application granted granted Critical
Publication of DE69730314T2 publication Critical patent/DE69730314T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69730314T 1996-02-21 1997-02-19 Dosierungsform von ibuprofen Expired - Lifetime DE69730314T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9603699.1A GB9603699D0 (en) 1996-02-21 1996-02-21 Therapeutic composition
GB9603699 1996-02-21
PCT/EP1997/000841 WO1997030699A2 (en) 1996-02-21 1997-02-19 Dosage form of ibuprofen

Publications (2)

Publication Number Publication Date
DE69730314D1 DE69730314D1 (de) 2004-09-23
DE69730314T2 true DE69730314T2 (de) 2005-08-18

Family

ID=10789176

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69730314T Expired - Lifetime DE69730314T2 (de) 1996-02-21 1997-02-19 Dosierungsform von ibuprofen

Country Status (25)

Country Link
US (1) US20020034540A1 (enExample)
EP (1) EP0881899B1 (enExample)
JP (2) JP2000507922A (enExample)
KR (1) KR19990087084A (enExample)
CN (1) CN1215989A (enExample)
AT (1) ATE273696T1 (enExample)
AU (1) AU722991B2 (enExample)
BG (1) BG64165B1 (enExample)
CA (1) CA2246344C (enExample)
CZ (1) CZ298371B6 (enExample)
DE (1) DE69730314T2 (enExample)
DK (1) DK0881899T3 (enExample)
ES (1) ES2227670T3 (enExample)
GB (1) GB9603699D0 (enExample)
HU (1) HUP9901454A3 (enExample)
IL (1) IL125803A0 (enExample)
NO (1) NO983825L (enExample)
NZ (1) NZ331416A (enExample)
PL (1) PL187383B1 (enExample)
PT (1) PT881899E (enExample)
RU (1) RU2182000C2 (enExample)
SK (1) SK285032B6 (enExample)
UA (1) UA55407C2 (enExample)
WO (1) WO1997030699A2 (enExample)
ZA (1) ZA971446B (enExample)

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IT1301966B1 (it) * 1998-07-30 2000-07-20 Zambon Spa Composizioni farmaceutiche ad attivita' analgesica
US20030026835A1 (en) * 1999-02-15 2003-02-06 Sumitomo Pharmaceuticals Company Limited Tablets disintegrating rapidly in the oral cavity
US6368618B1 (en) 1999-07-01 2002-04-09 The University Of Georgia Research Foundation, Inc. Composition and method for enhanced transdermal absorption of nonsteroidal anti-inflammatory drugs
NZ508292A (en) * 1999-11-24 2002-08-28 Mcneil Ppc Inc Treatment of migraine symptoms with ibuprofen and salts thereof
KR100523242B1 (ko) * 2000-05-18 2005-10-24 한미약품 주식회사 이부프로펜을 함유하는 정제 조성물
WO2002083105A2 (en) * 2001-04-10 2002-10-24 Zagros Pharma Inc. Composition for enhanced absorption of nsaids
CH693586A8 (de) * 2002-10-14 2003-12-15 Roche Consumer Health Ag Darreichungsform von Ibuprofen-Natrium.
CA2510320C (en) * 2002-12-20 2012-10-09 St. James Associates Llc/Faber Research Series Coated particles for sustained-release pharmaceutical administration
US20040176234A1 (en) * 2003-03-07 2004-09-09 Baker Hughes Incorporated Method for improving separation operation of centrifuges and associated improved separation designs
US20080020042A1 (en) * 2003-10-14 2008-01-24 Peter Gruber Dosage form of sodium ibuprofen
PE20050445A1 (es) * 2003-10-30 2005-06-18 Bayer Consumer Care Ag Forma de presentacion del naproxeno sodico
US20050266031A1 (en) 2004-05-25 2005-12-01 Jay Dickerson Pharmaceutical suspension composition
US8216610B2 (en) * 2004-05-28 2012-07-10 Imaginot Pty Ltd. Oral paracetamol formulations
CA2566384C (en) * 2004-05-28 2010-08-03 Imaginot Pty Ltd. Oral therapeutic compound delivery system
US20070218128A1 (en) * 2004-06-29 2007-09-20 Poul Bertelsen Manufacturing of Quick Release Pharmaceutical Compositions of Water Insoluble Drugs and Pharmaceutical Compositions Obtained By the Process of the Invention
EP1804772B1 (en) * 2004-08-12 2011-10-05 Reckitt Benckiser Healthcare (UK) Limited Granules comprising a non-steroidal anti-inflammatory drug and a sugar alcohol made by melt extrusion
US20060068009A1 (en) * 2004-09-30 2006-03-30 Scolr Pharma, Inc. Modified release ibuprofen dosage form
ZA200702694B (en) * 2004-09-30 2008-07-30 Scolr Pharma Inc Modified release ibuprofen dosage form
US20070077297A1 (en) * 2004-09-30 2007-04-05 Scolr Pharma, Inc. Modified release ibuprofen dosage form
EP1817021A1 (en) * 2004-11-03 2007-08-15 Equitech Corporation Nsaid compositions exhibiting clinical superiority
PT1850834E (pt) * 2005-02-09 2014-10-27 Boehringer Ingelheim Int Comprimidos revestidos por um filme, contendo lisinato de ibuprofeno
PT2559430E (pt) 2005-03-22 2015-10-09 Stada Arzneimittel Ag Ibuprofeno solubilizado
EP1800667A1 (en) 2005-12-23 2007-06-27 Losan Pharma GmbH Rapidly solubilizing ibuprofen granulate
CA2622704A1 (en) * 2005-09-19 2007-03-29 Albemarle Corporation Highly concentrated pourable aqueous solutions of potassium ibuprofen their preparation and their uses
US7811604B1 (en) 2005-11-14 2010-10-12 Barr Laboratories, Inc. Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same
JP2009517346A (ja) 2005-11-28 2009-04-30 イメイジノット ピーティーワイ エルティーディー 治療用化合物の経口送達系
KR101288924B1 (ko) * 2006-08-16 2013-07-24 에스에스 세야쿠 가부시키 가이샤 경구투여용 제제
US8951562B2 (en) * 2006-11-10 2015-02-10 Atacama Labs Oy Method and apparatus or dry granulation
FI20080348A0 (fi) * 2008-02-15 2008-05-09 Atacama Labs Oy Uudenlainen farmaseuttinen formulaatio
FI20070521A7 (fi) 2006-11-10 2008-05-11 Atacama Labs Oy Rakeita, tabletteja ja rakeistusmenetelmä
US7749537B2 (en) * 2006-12-04 2010-07-06 Scolr Pharma, Inc. Method of forming a tablet
AU2007338843B2 (en) * 2006-12-20 2013-05-09 Teva Women's Health, Inc. Orally disintegrating solid dosage forms comprising progestin and methods of making and use thereof
WO2009135946A1 (en) * 2008-05-09 2009-11-12 Atacama Labs Oy Method and apparatus for dry granulation
US9629809B2 (en) * 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
JP5553830B2 (ja) 2008-07-21 2014-07-16 アルベマール・コーポレーシヨン 高含量イブプロフェンナトリウム顆粒、その調製、および非発泡性固体剤形を調製する際のその使用
US20110144207A1 (en) * 2008-08-14 2011-06-16 Shasun Chemicals And Drugs Limited Aryl alkyl carboxylic acid salts, process for preparation and dosage forms
AU2014200704C1 (en) * 2009-06-22 2018-12-06 Pf Consumer Healthcare 1 Llc Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen
AU2015264861C1 (en) * 2009-06-22 2017-11-16 Pf Consumer Healthcare 1 Llc Sodium ibuprofen tablets and methods of manufacturing pharmaceutical compositions including sodium ibuprofen
CN104922084B (zh) * 2009-06-22 2020-01-14 惠氏有限责任公司 布洛芬钠片剂和制备包含布洛芬钠的药物组合物的方法
JP5974469B2 (ja) * 2010-12-24 2016-08-23 ライオン株式会社 錠剤の製造方法
CN103102259B (zh) * 2011-12-23 2014-02-26 海南正瑞医药科技开发有限公司 一种布洛芬水合物晶体、及含该水合物晶体的药物组合物及其制备方法
KR101890649B1 (ko) * 2013-07-30 2018-09-28 라이온 가부시키가이샤 정제
EP2845850A1 (en) 2013-09-10 2015-03-11 ObsEva S.A. Pyrrolidine derivatives as oxytocin/vasopressin V1a receptors antagonists
EP2886107A1 (en) * 2013-12-17 2015-06-24 ObsEva S.A. Oral formulations of pyrrolydine derivatives
KR102470283B1 (ko) 2014-07-02 2022-11-23 옵스에파 에스에이 결정질 (3z,5s)-5-(하이드록시메틸)-1-[(2'-메틸-1,1'-바이페닐-4-일)카르보닐]피롤리딘-3-온 o-메틸옥심
EP2965746B1 (en) 2014-07-10 2019-03-13 Santa Farma Ilaç Sanayi A.S. An oral pharmaceutical composition comprising ibuprofen, ibuprofen sodium dihydrate, pseudoephedrine hydrochloride and chlorpheniramine maleate
WO2017060920A1 (en) * 2015-10-05 2017-04-13 Strides Shasun Limited Pharmaceutical compositions

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4681897A (en) * 1984-01-16 1987-07-21 The Procter & Gamble Company Pharmaceutical products providing enhanced analgesia
DE3440288C2 (de) * 1984-11-05 1987-03-12 Gergely, Gerhard, Dr.-Ing., Wien Pharmazeutische Zubereitung mit einem Gehalt an Ibuprofen sowie Verfahren zu ihrer Herstellung
US4684666A (en) * 1986-08-19 1987-08-04 Haas Pharmaceuticals, Inc. Stabilized liquid analgesic compositions
AU8320387A (en) * 1986-10-22 1988-05-25 Upjohn Company, The Treatment of gingivitis with ibuprofen or flurbiprofen
US4788220A (en) * 1987-07-08 1988-11-29 American Home Products Corporation (Del.) Pediatric ibuprofen compositions
US4837031A (en) * 1987-09-17 1989-06-06 Mallinckrodt, Inc. Compositions containing ibuprofen
DE3922441A1 (de) * 1989-07-07 1991-01-17 Pharmatrans Sanaq Ag Ibuprofen- und s-(+)-ibuprofen-zubereitungen und verfahren zu ihrer herstellung
ES2148175T3 (es) * 1991-05-13 2000-10-16 Boots Co Plc Composicion farmaceutica que contiene una sal de ibuprofeno.
DE4216756C2 (de) * 1992-05-21 1994-08-25 Pharmatrans Sanaq Ag 2-Arylpropionsäure-Zubereitungen und Verfahren zu ihrer Herstellung
DE59209706D1 (de) * 1992-12-01 1999-07-08 Spirig Ag S(+)-Ibuprofen enthaltende Arzneimittel

Also Published As

Publication number Publication date
NO983825L (no) 1998-10-20
EP0881899A2 (en) 1998-12-09
PL328465A1 (en) 1999-02-01
DE69730314D1 (de) 2004-09-23
ZA971446B (en) 1997-11-25
CN1215989A (zh) 1999-05-05
CZ261798A3 (cs) 1998-11-11
JP2000507922A (ja) 2000-06-27
JP2009073847A (ja) 2009-04-09
UA55407C2 (uk) 2003-04-15
BG64165B1 (bg) 2004-03-31
SK285032B6 (sk) 2006-05-04
SK114298A3 (en) 1999-01-11
NO983825D0 (no) 1998-08-20
US20020034540A1 (en) 2002-03-21
RU2182000C2 (ru) 2002-05-10
ES2227670T3 (es) 2005-04-01
WO1997030699A2 (en) 1997-08-28
HUP9901454A2 (hu) 1999-08-30
HUP9901454A3 (en) 2001-04-28
WO1997030699A3 (en) 1997-10-09
PT881899E (pt) 2004-12-31
CA2246344C (en) 2009-01-20
ATE273696T1 (de) 2004-09-15
IL125803A0 (en) 1999-04-11
EP0881899B1 (en) 2004-08-18
CZ298371B6 (cs) 2007-09-12
KR19990087084A (ko) 1999-12-15
NZ331416A (en) 2000-02-28
AU722991B2 (en) 2000-08-17
AU1793797A (en) 1997-09-10
BG102744A (bg) 1999-05-31
DK0881899T3 (da) 2004-12-20
GB9603699D0 (en) 1996-04-17
CA2246344A1 (en) 1997-08-28
PL187383B1 (pl) 2004-06-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: RECKITT BENCKISER HEALTHCARE INTERNATIONAL LTD, GB

8327 Change in the person/name/address of the patent owner

Owner name: RECKITT BENCKISER HEALTHCARE (UK) LTD., SLOUGH, GB