DE69724999D1 - Mikropartikularform eines tetrahydropyridinderivates - Google Patents

Mikropartikularform eines tetrahydropyridinderivates

Info

Publication number
DE69724999D1
DE69724999D1 DE69724999T DE69724999T DE69724999D1 DE 69724999 D1 DE69724999 D1 DE 69724999D1 DE 69724999 T DE69724999 T DE 69724999T DE 69724999 T DE69724999 T DE 69724999T DE 69724999 D1 DE69724999 D1 DE 69724999D1
Authority
DE
Germany
Prior art keywords
tetrahydropyridine derivative
microparticular form
microparticular
tetrahydropyridine
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69724999T
Other languages
English (en)
Other versions
DE69724999T2 (de
Inventor
Antoine Caron
Jean-Pierre Chambon
Olivier Monnier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo SA filed Critical Sanofi Synthelabo SA
Application granted granted Critical
Publication of DE69724999D1 publication Critical patent/DE69724999D1/de
Publication of DE69724999T2 publication Critical patent/DE69724999T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
DE69724999T 1996-12-23 1997-12-23 Mikropartikularform eines tetrahydropyridinderivates Expired - Lifetime DE69724999T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9615905A FR2757510B1 (fr) 1996-12-23 1996-12-23 Forme microparticulaire d'un derive de tetrahydropyridine
FR9615905 1996-12-23
PCT/FR1997/002394 WO1998028272A1 (fr) 1996-12-23 1997-12-23 Forme microparticulaire d'un derive de tetrahydropyridine

Publications (2)

Publication Number Publication Date
DE69724999D1 true DE69724999D1 (de) 2003-10-23
DE69724999T2 DE69724999T2 (de) 2004-07-22

Family

ID=9499044

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69724999T Expired - Lifetime DE69724999T2 (de) 1996-12-23 1997-12-23 Mikropartikularform eines tetrahydropyridinderivates

Country Status (38)

Country Link
US (4) US20020028247A1 (de)
EP (1) EP0950051B1 (de)
JP (2) JP4422214B2 (de)
KR (1) KR100455797B1 (de)
CN (1) CN1088698C (de)
AR (1) AR009673A1 (de)
AT (1) ATE250032T1 (de)
AU (1) AU730302B2 (de)
BR (1) BR9714177A (de)
CA (1) CA2275593C (de)
CO (1) CO4920213A1 (de)
CZ (1) CZ294272B6 (de)
DE (1) DE69724999T2 (de)
DK (1) DK0950051T3 (de)
DZ (1) DZ2386A1 (de)
EE (1) EE04112B1 (de)
EG (1) EG24749A (de)
ES (1) ES2207758T3 (de)
FR (1) FR2757510B1 (de)
HK (1) HK1024000A1 (de)
HU (1) HU224348B1 (de)
IL (1) IL129937A (de)
IN (1) IN186977B (de)
IS (1) IS2064B (de)
MY (1) MY126298A (de)
NO (1) NO311569B1 (de)
NZ (1) NZ336129A (de)
PL (1) PL190098B1 (de)
PT (1) PT950051E (de)
RU (1) RU2193031C2 (de)
SI (1) SI0950051T1 (de)
SK (1) SK283917B6 (de)
TR (1) TR199901362T2 (de)
TW (1) TW534820B (de)
UA (1) UA66776C2 (de)
WO (1) WO1998028272A1 (de)
YU (1) YU49427B (de)
ZA (1) ZA9711579B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4570357B2 (ja) * 2001-07-06 2010-10-27 ライフサイクル ファーマ エー／エス 制御された凝集
BE1015641A4 (fr) * 2003-05-26 2005-07-05 Mariani Jean Paul Micronisation 70.
RU2472490C1 (ru) * 2011-08-05 2013-01-20 Открытое акционерное общество "Биосинтез" Средство для лечения кожных гнойных инфекций, составы и способы получения

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US562883A (en) * 1896-06-30 Thill-coupling
FR2531707A1 (fr) * 1982-08-16 1984-02-17 Midy Spa Trifluoromethylphenyltetrahydropyridines substituees a activite anorexigene, un procede de preparation et compositions pharmaceutiques
US4826689A (en) * 1984-05-21 1989-05-02 University Of Rochester Method for making uniformly sized particles from water-insoluble organic compounds
FR2627696B1 (fr) * 1988-02-26 1991-09-13 Fournier Innovation Synergie Nouvelle forme galenique du fenofibrate
FR2639226B1 (fr) * 1988-11-18 1993-11-05 Sanofi Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles anxio-depressifs
FR2662355B1 (fr) * 1990-05-22 1994-11-10 Sanofi Sa Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
CA2126685C (en) * 1992-10-26 2002-07-23 Bruno Gander Process for the production of microcapsules
US5662883A (en) * 1995-01-10 1997-09-02 Nanosystems L.L.C. Microprecipitation of micro-nanoparticulate pharmaceutical agents
US5560932A (en) * 1995-01-10 1996-10-01 Nano Systems L.L.C. Microprecipitation of nanoparticulate pharmaceutical agents
US6489334B2 (en) * 1996-12-23 2002-12-03 Sanofi-Synthelabo Method for the crystallization of a tetrahydropyridin derivative and resulting crystalline forms
FR2763847B1 (fr) * 1997-05-28 2003-06-06 Sanofi Sa Utilisation de tetrahydropyridines 4-substituees pour fabriquer des medicaments agissant sur le tgf-beta-1
US20020147216A1 (en) * 2000-01-31 2002-10-10 Yuhong Zhou Mucin synthesis inhibitors

Also Published As

Publication number Publication date
SI0950051T1 (en) 2004-02-29
JP2001507013A (ja) 2001-05-29
CN1088698C (zh) 2002-08-07
DE69724999T2 (de) 2004-07-22
IL129937A0 (en) 2000-02-29
CO4920213A1 (es) 2000-05-29
HU224348B1 (hu) 2005-08-29
HK1024000A1 (en) 2000-09-29
YU28899A (sh) 2000-03-21
CZ229199A3 (cs) 1999-09-15
AR009673A1 (es) 2000-04-26
DK0950051T3 (da) 2004-01-26
NO311569B1 (no) 2001-12-10
RU2193031C2 (ru) 2002-11-20
JP2009280581A (ja) 2009-12-03
TR199901362T2 (xx) 1999-09-21
US20020192292A1 (en) 2002-12-19
CN1241179A (zh) 2000-01-12
EE04112B1 (et) 2003-08-15
ES2207758T3 (es) 2004-06-01
NO993077D0 (no) 1999-06-22
FR2757510B1 (fr) 2000-01-07
EE9900263A (et) 2000-02-15
HUP0001181A2 (hu) 2000-11-28
DZ2386A1 (fr) 2002-12-28
EP0950051B1 (de) 2003-09-17
ATE250032T1 (de) 2003-10-15
KR20000069503A (ko) 2000-11-25
CA2275593C (en) 2005-12-20
IN186977B (de) 2001-12-22
BR9714177A (pt) 2000-02-29
CZ294272B6 (cs) 2004-11-10
US20020028247A1 (en) 2002-03-07
JP4422214B2 (ja) 2010-02-24
PL190098B1 (pl) 2005-10-31
TW534820B (en) 2003-06-01
YU49427B (sh) 2006-01-16
KR100455797B1 (ko) 2004-11-06
SK82999A3 (en) 1999-12-10
PL334276A1 (en) 2000-02-14
ZA9711579B (en) 1998-06-25
PT950051E (pt) 2004-02-27
UA66776C2 (uk) 2004-06-15
EP0950051A1 (de) 1999-10-20
US20100021541A1 (en) 2010-01-28
IL129937A (en) 2002-09-12
AU730302B2 (en) 2001-03-01
WO1998028272A1 (fr) 1998-07-02
US20080255365A1 (en) 2008-10-16
SK283917B6 (sk) 2004-05-04
CA2275593A1 (en) 1998-07-02
FR2757510A1 (fr) 1998-06-26
IS5077A (is) 1999-06-10
AU5668598A (en) 1998-07-17
IS2064B (is) 2005-11-15
NO993077L (no) 1999-06-22
HUP0001181A3 (en) 2003-03-28
MY126298A (en) 2006-09-29
NZ336129A (en) 2000-11-24
EG24749A (en) 2010-07-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SANOFI-AVENTIS, PARIS, FR