DE69637459D1 - Intranasaler Medikator - Google Patents

Intranasaler Medikator

Info

Publication number
DE69637459D1
DE69637459D1 DE69637459T DE69637459T DE69637459D1 DE 69637459 D1 DE69637459 D1 DE 69637459D1 DE 69637459 T DE69637459 T DE 69637459T DE 69637459 T DE69637459 T DE 69637459T DE 69637459 D1 DE69637459 D1 DE 69637459D1
Authority
DE
Germany
Prior art keywords
intranasal
medicament
intranasal medicament
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69637459T
Other languages
English (en)
Other versions
DE69637459T2 (de
Inventor
Hisatomo Ohki
Shigemi Nakamura
Kazunori Ishizeki
Akira Yanagawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dott Co Ltd
Hitachi Ltd
Original Assignee
Dott Co Ltd
Hitachi Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP04230995A external-priority patent/JP3308419B2/ja
Priority claimed from JP11125295A external-priority patent/JP3273712B2/ja
Application filed by Dott Co Ltd, Hitachi Ltd filed Critical Dott Co Ltd
Publication of DE69637459D1 publication Critical patent/DE69637459D1/de
Application granted granted Critical
Publication of DE69637459T2 publication Critical patent/DE69637459T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/06—Inhaling appliances shaped like cigars, cigarettes or pipes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/07—General characteristics of the apparatus having air pumping means
    • A61M2205/071—General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/075—Bulb type

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
DE69637459T 1995-02-06 1996-02-06 Intranasaler Medikator Expired - Lifetime DE69637459T2 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP04230995A JP3308419B2 (ja) 1995-02-06 1995-02-06 鼻腔用投薬器
JP4230995 1995-02-06
JP4230695 1995-02-06
JP4230695 1995-02-06
JP11125295A JP3273712B2 (ja) 1995-02-06 1995-04-12 鼻腔用投薬器
JP11125295 1995-04-12
PCT/JP1996/000242 WO1996024400A1 (fr) 1995-02-06 1996-02-06 Dispositif d'administration d'un medicament par voie intranasale

Publications (2)

Publication Number Publication Date
DE69637459D1 true DE69637459D1 (de) 2008-04-24
DE69637459T2 DE69637459T2 (de) 2009-03-05

Family

ID=27291156

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69637459T Expired - Lifetime DE69637459T2 (de) 1995-02-06 1996-02-06 Intranasaler Medikator

Country Status (6)

Country Link
US (1) US5901703A (de)
EP (1) EP0753319B1 (de)
KR (1) KR100187737B1 (de)
CN (1) CN1146729A (de)
DE (1) DE69637459T2 (de)
WO (1) WO1996024400A1 (de)

Families Citing this family (91)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6428771B1 (en) * 1995-05-15 2002-08-06 Pharmaceutical Discovery Corporation Method for drug delivery to the pulmonary system
JP3317823B2 (ja) * 1995-08-11 2002-08-26 株式会社ユニシアジェックス 投薬器
DE69839356T2 (de) 1997-01-30 2009-06-25 Dott Ltd. Co., Yokohama Trockenpulverinhalator für Kapseln
FR2764807B1 (fr) * 1997-06-18 1999-08-20 Valois Sa Dispositif de distribution nasale d'un produit fluide ou pulverulent
FR2771012B1 (fr) * 1997-11-17 2000-03-10 Sofab Pulverisateur nasal
JP3488620B2 (ja) 1998-02-05 2004-01-19 株式会社日立ユニシアオートモティブ 吸入式投薬器
JP2000217917A (ja) 1999-01-27 2000-08-08 Unisia Jecs Corp 吸入式投薬器
PT1808438E (pt) * 1999-06-29 2015-01-14 Mannkind Corp Purificação e estabilização de péptidos e proteínas em agentes farmacêuticos
US9006175B2 (en) * 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6606992B1 (en) * 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
US7305986B1 (en) * 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US7464706B2 (en) 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
DE10006026A1 (de) * 2000-02-10 2001-08-23 Birgit Vaassen Applikator mit zwei Schaften
US6644305B2 (en) * 2000-04-14 2003-11-11 Trudell Medical International Nasal inhaler
ZA200306564B (en) * 2001-02-26 2004-10-15 Optinose As Nasal devices.
ITMI20010357U1 (it) * 2001-06-28 2002-12-30 Plastiape Spa Dispositivo inalatore
US20030041860A1 (en) * 2001-08-29 2003-03-06 Verona Steven N. Particulate dispenser
WO2003041777A1 (en) * 2001-11-14 2003-05-22 Nektar Therapeutics Aerosolization device with improved endpiece connection
WO2003041776A1 (en) * 2001-11-14 2003-05-22 Nektar Therapeutics Aerosolization apparatus comprising connectable body and endpiece
ATE385193T1 (de) 2002-03-20 2008-02-15 Mannkind Corp Inhalationsgerät
AU2003220808B2 (en) * 2003-03-27 2008-08-21 Bioactis Limited Powder medicine applicator for nasal cavity
JP4542090B2 (ja) 2003-04-09 2010-09-08 ネクター セラピューティクス カプセル穿刺整合ガイドを有するエアロゾル化装置
US7338171B2 (en) * 2003-10-27 2008-03-04 Jen-Chuen Hsieh Method and apparatus for visual drive control
US20070199568A1 (en) * 2003-12-15 2007-08-30 Bespak Plc (Incorporated In The United Kingdom) Nasal drug delivery
WO2005067964A1 (en) * 2004-01-12 2005-07-28 Mannkind Corporation A method of reducing serum proinsulin levels in type 2 diabetics
ATE433746T1 (de) * 2004-03-12 2009-07-15 Biodel Inc Insulinzusammensetzungen mit verbesserter wirkstoffabsorption
US20080248999A1 (en) * 2007-04-04 2008-10-09 Biodel Inc. Amylin formulations
US20080090753A1 (en) 2004-03-12 2008-04-17 Biodel, Inc. Rapid Acting Injectable Insulin Compositions
CN1946453A (zh) * 2004-04-23 2007-04-11 米斯提克医药有限公司 多倍剂量药品配给系统
US7204246B1 (en) * 2004-07-08 2007-04-17 Joseph Berinato Air self-contained oxygen inhaler
CA2575692C (en) 2004-08-20 2014-10-14 Mannkind Corporation Catalysis of diketopiperazine synthesis
BR122019022692B1 (pt) 2004-08-23 2023-01-10 Mannkind Corporation Composição terapêutica em pó seco contendo dicetopiperazina, pelo menos um tipo de cátion e um agente biologicamente ativo
DK1937219T3 (en) 2005-09-14 2016-02-15 Mannkind Corp A method for drug formulation based on increasing the affinity of the crystalline surfaces of the microparticle of active principles
US8084420B2 (en) * 2005-09-29 2011-12-27 Biodel Inc. Rapid acting and long acting insulin combination formulations
WO2007041481A1 (en) * 2005-09-29 2007-04-12 Biodel, Inc. Rapid acting and prolonged acting insulin preparations
US7713929B2 (en) 2006-04-12 2010-05-11 Biodel Inc. Rapid acting and long acting insulin combination formulations
IN2015DN00888A (de) 2006-02-22 2015-07-10 Mannkind Corp
GB0605799D0 (en) 2006-03-23 2006-05-03 Optinose As Nasal delivery devices
US7718609B2 (en) * 2006-04-12 2010-05-18 Biodel Inc. Rapid acting and long acting insulin combination formulations
WO2008026730A1 (fr) * 2006-08-31 2008-03-06 Hitachi, Ltd. Vaporisateur médical
CA2675030C (en) 2007-01-09 2015-06-09 Mystic Pharmaceuticals, Inc. Intranasal cartridge devices
US9248076B2 (en) 2007-05-16 2016-02-02 Mystic Pharmaceuticals, Inc. Dose dispensing containers
EP2164799B1 (de) * 2007-05-16 2018-12-26 Mystic Pharmaceuticals, Inc. Kombinationsdosiereinheitabgabebehälter
US8683995B2 (en) 2007-05-16 2014-04-01 Mystic Pharmaceuticals, Inc. Dose dispensing containers
JP2010538925A (ja) * 2007-09-14 2010-12-16 ミスティック ファーマシューティカルズ， インコーポレイテッド 深絞り容器成形方法
US8785396B2 (en) 2007-10-24 2014-07-22 Mannkind Corporation Method and composition for treating migraines
CN101951957A (zh) * 2008-01-04 2011-01-19 百达尔公司 胰岛素释放作为组织的葡萄糖水平的函数的胰岛素制剂
ES2648196T3 (es) 2008-02-07 2017-12-29 The University Of Washington Dispositivo aerosol circunferencial
JP5667041B2 (ja) * 2008-03-27 2015-02-12 マンカインド コーポレイション 乾燥粉末吸入システム
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
KR101933816B1 (ko) 2008-06-13 2019-03-29 맨카인드 코포레이션 건조 분말 흡입기 및 약물 투여 시스템
EP2609954B1 (de) 2008-06-20 2021-12-29 MannKind Corporation Interaktives Gerät für die Echtzeit-Profilierung von Inhalationsversuchen
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US9060927B2 (en) * 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
US8538707B2 (en) 2009-03-11 2013-09-17 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
MY157166A (en) 2009-06-12 2016-05-13 Mankind Corp Diketopiperazine microparticles with defined specific surface areas
JP5784622B2 (ja) 2009-11-03 2015-09-24 マンカインド コーポレ−ション 吸入活動をシミュレートするための装置及び方法
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
BR112013022249B8 (pt) 2011-03-03 2022-10-25 Impel Neuropharma Inc Dispositivo de distribuição de droga nasal
JP6133270B2 (ja) 2011-04-01 2017-05-24 マンカインド コーポレイション 薬剤カートリッジのためのブリスター包装
CN103619485B (zh) 2011-05-09 2017-08-08 英倍尔药业股份有限公司 用于鼻腔药物递送的喷嘴
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
CA2852536A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
ES2624294T3 (es) 2012-07-12 2017-07-13 Mannkind Corporation Sistemas de suministro de fármacos en polvo seco
EP2911690A1 (de) 2012-10-26 2015-09-02 MannKind Corporation Inhalierbare influenza-impfstoffzusammensetzungen und verfahren
EP2970149B1 (de) 2013-03-15 2019-08-21 MannKind Corporation Mikrokristalline diketopiperazinzusammensetzungen und verfahren
WO2014179228A1 (en) 2013-04-28 2014-11-06 Impel Neuropharma Inc. Medical unit dose container
CN103285503A (zh) * 2013-06-06 2013-09-11 魏永祥 一种粉末药剂喷药瓶
BR112016000937A8 (pt) 2013-07-18 2021-06-22 Mannkind Corp formulações farmacêuticas de pó seco, método para a fabricação de uma formulação de pó seco e uso de uma formulação farmacêutica de pó seco
CA2920488C (en) 2013-08-05 2022-04-26 Mannkind Corporation Insufflation apparatus and methods
USD752204S1 (en) 2014-03-10 2016-03-22 Civitas Therapeutics, Inc. Indicator for an inhaler
NO2709641T3 (de) * 2014-03-10 2018-05-12
USD755367S1 (en) 2014-03-10 2016-05-03 Civitas Therapeutics, Inc. Indicator for an inhaler
USD752734S1 (en) 2014-03-10 2016-03-29 Civitas Therapeutics, Inc. Inhaler grip
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
CN107106792B (zh) 2014-11-19 2020-08-18 奥普蒂诺斯公司 经鼻给药
CN105054979B (zh) * 2015-08-29 2018-02-23 江阴迪林生物电子技术有限公司 一种电动鼻腔采样给药器
JP6753927B2 (ja) 2015-09-10 2020-09-09 インペル ニューロファーマ インコーポレイテッド 直列形経鼻送達デバイス
CA3065307C (en) * 2017-06-01 2022-06-07 Counteract, Llc Prescription bottle cap capable of administering opioid overdose reversal agent
USD828543S1 (en) * 2017-08-01 2018-09-11 Khanquer Pharma, Inc. Dual nostril nasal spray device
US11744967B2 (en) * 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
WO2019104192A1 (en) 2017-11-21 2019-05-31 Impel Neuropharma, Inc. Intranasal device with inlet interface
WO2019104205A1 (en) 2017-11-21 2019-05-31 Impel Neuropharma, Inc. Intranasal device with dip tube
AU2019205318B2 (en) 2018-01-05 2022-02-03 Impel Pharmaceuticals Inc. Intranasal delivery of dihydroergotamine by precision olfactory device
JP2021509677A (ja) 2018-01-05 2021-04-01 インペル ニューロファーマ インコーポレイテッド 精密嗅覚装置によるオランザピンの鼻孔間送達
CN112955134A (zh) 2018-07-19 2021-06-11 英倍尔药业股份有限公司 用于治疗帕金森氏病的左旋多巴和多巴脱羧酶抑制剂的呼吸道递送
KR20210109007A (ko) 2019-01-03 2021-09-03 임펠 뉴로파마 인코포레이티드 비강 약물 전달 장치
EP3969085A4 (de) 2019-05-17 2023-06-21 Impel Pharmaceuticals Inc. Einwegvorrichtung zur nasalen verabreichung
CN111514418B (zh) * 2019-06-12 2022-01-14 中南大学湘雅二医院 一种自吸式经鼻粉末材料给送装置

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3949751A (en) * 1970-03-03 1976-04-13 Fisons Limited Method and device for dispensing medicament to the body
FR2224175B1 (de) * 1973-04-04 1978-04-14 Isf Spa
DE2960616D1 (en) * 1978-05-03 1981-11-12 Fisons Plc Inhalation device
JPS5934267A (ja) * 1982-08-23 1984-02-24 帝人株式会社 粉状薬剤施薬装置
DE3345722A1 (de) * 1983-12-17 1985-06-27 Boehringer Ingelheim KG, 6507 Ingelheim Inhalator
IT1222509B (it) * 1987-08-17 1990-09-05 Miat Spa Insufflatore per la somministrazione di farmaci sotto forma di polvere predosata in opercoli
JPH0410847Y2 (de) * 1987-11-30 1992-03-17
IT1228459B (it) * 1989-02-23 1991-06-19 Phidea S R L Inalatore con svuotamento regolare e completo della capsula.
JPH033998A (ja) * 1989-05-31 1991-01-10 Kanichi Mitsunaka 多目的扇風機
DE3927170A1 (de) * 1989-08-17 1991-02-21 Boehringer Ingelheim Kg Inhalator
IT1240750B (it) * 1990-04-12 1993-12-17 Chiesi Farma Spa Dispositivo per la somministrazione di sostanze medicamentose in polvere
AU650953B2 (en) * 1991-03-21 1994-07-07 Novartis Ag Inhaler
DK103191D0 (da) * 1991-05-31 1991-05-31 Novo Nordisk As Nasaldispenser
JP3003998U (ja) * 1994-05-09 1994-11-01 公偉 川上 臭覚補助具
JP3388896B2 (ja) * 1994-08-08 2003-03-24 株式会社日立ユニシアオートモティブ 吸入式投薬器
JP3320261B2 (ja) * 1995-06-01 2002-09-03 株式会社ユニシアジェックス 吸入式投薬器

Also Published As

Publication number Publication date
EP0753319B1 (de) 2008-03-12
WO1996024400A1 (fr) 1996-08-15
KR100187737B1 (ko) 1999-06-01
EP0753319A1 (de) 1997-01-15
US5901703A (en) 1999-05-11
DE69637459T2 (de) 2009-03-05
EP0753319A4 (de) 1999-11-17
KR970701572A (ko) 1997-04-12
CN1146729A (zh) 1997-04-02

Similar Documents

Publication Publication Date Title
DE69637459D1 (de) Intranasaler Medikator
DK0822982T3 (da) Cyclomaltodextringlucanotransferasevarianter
NO965223D0 (no) Helletutsammenstilling
ATA135896A (de) Skibob
IS4541A (is) Clavúlansýrusölt
ATE198470T1 (de) Alkenyl-benzoylguanidine
ATE240972T1 (de) Cyclopeptolide
ATA119896A (de) Scheibenmähwerk
BR9501643A (pt) Helistato
BR9503866A (pt) Autolabor
FI955570A0 (fi) Seen
FI2214U1 (fi) Madrasskonstruktion
FI1910U1 (fi) Postlaodsystem
FIU950095U0 (fi) Taeltkamin
BR7501299U (pt) Geladeira-prática
BR9500079A (pt) Bomballoon
BR7500040U (pt) Raquet mastit
BR9505079A (pt) Supersônico-a-hélice
BR9500075A (pt) Carrapetilha
BR9502958A (pt) Artermogeo
BR7502937U (pt) Floco-decantador multicone
BR9502885A (pt) Casarreal
BR7502853U (pt) Faixa-surf
FI973008A (fi) Painevesiflotaatiolaitteisto
BR9502823A (pt) Proteserra

Legal Events

Date Code Title Description
8364 No opposition during term of opposition