DE69534592D1 - Verfahren für die herstellung von l-lysin - Google Patents
Verfahren für die herstellung von l-lysinInfo
- Publication number
- DE69534592D1 DE69534592D1 DE69534592T DE69534592T DE69534592D1 DE 69534592 D1 DE69534592 D1 DE 69534592D1 DE 69534592 T DE69534592 T DE 69534592T DE 69534592 T DE69534592 T DE 69534592T DE 69534592 D1 DE69534592 D1 DE 69534592D1
- Authority
- DE
- Germany
- Prior art keywords
- lysine
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1217—Phosphotransferases with a carboxyl group as acceptor (2.7.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3501994 | 1994-03-04 | ||
JP3501994 | 1994-03-04 | ||
PCT/JP1995/000268 WO1995023864A1 (fr) | 1994-03-04 | 1995-02-23 | Procede de production de l-lysine |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69534592D1 true DE69534592D1 (de) | 2005-12-15 |
DE69534592T2 DE69534592T2 (de) | 2006-08-10 |
Family
ID=12430364
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69534592T Expired - Lifetime DE69534592T2 (de) | 1994-03-04 | 1995-02-23 | Verfahren für die herstellung von l-lysin |
Country Status (8)
Country | Link |
---|---|
US (1) | US5766925A (de) |
EP (1) | EP0754756B1 (de) |
JP (1) | JP3783065B2 (de) |
CN (1) | CN1117152C (de) |
DE (1) | DE69534592T2 (de) |
DK (1) | DK0754756T3 (de) |
ES (1) | ES2249767T3 (de) |
WO (1) | WO1995023864A1 (de) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH1087A (ja) * | 1996-06-17 | 1998-01-06 | Ajinomoto Co Inc | 発酵法による目的物質の製造法 |
EP1004663B1 (de) * | 1997-07-18 | 2007-02-07 | Ajinomoto Co., Inc. | Verfahren und mikroorganism zur herstellung von purin-nukleosiden durch fermentation |
US6599732B1 (en) | 1999-06-29 | 2003-07-29 | Archer-Daniels-Midland Company | Regulation of carbon assimilation |
JP2003503064A (ja) * | 1999-06-29 | 2003-01-28 | アーカー−ダニエルズ−ミッドランド カンパニー | 炭素同化の調節 |
US6451564B1 (en) * | 1999-07-02 | 2002-09-17 | Massachusetts Institute Of Technology | Methods for producing L-isoleucine |
US6893852B1 (en) | 1999-07-02 | 2005-05-17 | Ajinomoto Co., Inc. | Dna encoding sucrose pts enzyme II |
US6984512B1 (en) * | 1999-08-02 | 2006-01-10 | Archer-Daniels-Midland Company | Bacterial strains, methods of preparing the same and use thereof in fermentation processes for L-lysine production |
AU779019B2 (en) * | 1999-08-02 | 2005-01-06 | Archer-Daniels-Midland Company | Metabolic engineering of amino acid production |
JP4306169B2 (ja) * | 1999-12-24 | 2009-07-29 | 味の素株式会社 | L−アミノ酸の製造法及び新規遺伝子 |
US6927046B1 (en) | 1999-12-30 | 2005-08-09 | Archer-Daniels-Midland Company | Increased lysine production by gene amplification using coryneform bacteria |
AU2001295456A1 (en) | 2000-09-12 | 2002-03-26 | Degussa A.G. | Nucleotide sequences which code for the gora gene |
US20020168732A1 (en) * | 2000-11-10 | 2002-11-14 | Bettina Moeckel | Process for the fermentative preparation of L-amino acids using coryneform bacteria |
IL156997A0 (en) | 2001-02-08 | 2004-02-08 | Archer Daniels Midland Co | Polynucleotide constructs for increased lysine production |
BR0304860A (pt) * | 2002-11-11 | 2004-08-31 | Ajinomoto Kk | Método para produzir uma substância alvo pela utilização de uma-bactéria pertencente ao gênero escherichia |
JP2004187684A (ja) * | 2002-11-26 | 2004-07-08 | Ajinomoto Co Inc | L−グルタミンの製造法及びl−グルタミン生産菌 |
DE60335774D1 (de) | 2002-11-26 | 2011-03-03 | Ajinomoto Kk | Methode für die Produktion von L-Glutamin und L-Glutamin-produzierendes Bakterium |
US20050255568A1 (en) * | 2003-05-30 | 2005-11-17 | Bailey Richard B | Methods and compositions for amino acid production |
KR20060018868A (ko) * | 2003-05-30 | 2006-03-02 | 마이크로비아 인코포레이티드 | 아미노산 생산 방법 및 아미노산 생산용 조성물 |
ATE462451T1 (de) * | 2004-06-16 | 2010-04-15 | Affinergy Inc | Grenzflächenbiomaterialien zur förderung der anhaftung von zielanalyten |
ES2941685T3 (es) | 2004-10-07 | 2023-05-24 | Ajinomoto Kk | Método para producción de una substancia básica |
KR100789270B1 (ko) * | 2005-11-30 | 2008-01-02 | 씨제이 주식회사 | L-라이신 생산능이 향상된 코리네박테리움 속 미생물 및그를 이용하여 l-라이신을 생산하는 방법 |
KR100733928B1 (ko) | 2005-11-30 | 2007-07-02 | 씨제이 주식회사 | 카나마이신 내성을 갖고 l-라이신 생산능이 향상된코리네형 미생물 및 그를 이용하여 l-라이신을 생산하는방법 |
EP1979486B1 (de) | 2006-01-30 | 2013-04-17 | Ajinomoto Co., Inc. | L-aminosäure-produzierendes bakterium und verfahren zur herstellung von l-aminosäure |
EP2055771A3 (de) | 2006-03-23 | 2009-07-08 | Ajinomoto Co., Inc. | Methode zur Produktion einer L-Aminosäure unter Verwendung eines Bakteriums der Enterobacteriaceae Familie mit einer abgeschwächten Expression eines Gens kodierend für sRNA |
EP2013353B1 (de) * | 2006-03-30 | 2016-06-22 | Basf Se | Verfahren zur herstellung von cadaverin |
JP2009153382A (ja) | 2006-03-30 | 2009-07-16 | Ajinomoto Co Inc | メタノール資化性細菌を用いたカルボン酸の製造法 |
US20070244719A1 (en) * | 2006-04-13 | 2007-10-18 | David Peter R | Compositions and methods for producing fermentation products and residuals |
US20070243235A1 (en) * | 2006-04-13 | 2007-10-18 | David Peter R | Compositions and methods for producing fermentation products and residuals |
US7309602B2 (en) * | 2006-04-13 | 2007-12-18 | Ambrozea, Inc. | Compositions and methods for producing fermentation products and residuals |
JP2010041920A (ja) | 2006-12-19 | 2010-02-25 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
BRPI0703692B1 (pt) | 2006-12-25 | 2016-12-27 | Ajinomoto Kk | método para se obter os cristais de um hidrocloreto de aminoácido básico compreendendo gerar um aminoácido básico usando células microbianas por fermentação em um caldo de fermentação ou por um método enzimático em uma solução de reação de enzima usando as células como catalisadores |
JP2010088301A (ja) | 2007-02-01 | 2010-04-22 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
JP2011067095A (ja) | 2008-01-10 | 2011-04-07 | Ajinomoto Co Inc | 発酵法による目的物質の製造法 |
BRPI0906795A2 (pt) | 2008-01-23 | 2015-08-18 | Ajinomoto Kk | Método para produzir um l-aminoácido |
JP2012029565A (ja) | 2008-11-27 | 2012-02-16 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
JP2010142200A (ja) | 2008-12-22 | 2010-07-01 | Ajinomoto Co Inc | L−リジンの製造法 |
JP5170012B2 (ja) * | 2009-06-26 | 2013-03-27 | 東レ株式会社 | カダベリン発酵コリネ型細菌を用いたポリアミドの製造方法 |
BRPI1014661B1 (pt) | 2009-07-29 | 2020-12-15 | Ajinomoto Co., Inc. | Método para produzir um l-aminoácido |
JP2012196144A (ja) | 2009-08-03 | 2012-10-18 | Ajinomoto Co Inc | ビブリオ属細菌を用いたl−リジンの製造法 |
JP2012223091A (ja) | 2009-08-25 | 2012-11-15 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
US8839078B2 (en) * | 2010-03-05 | 2014-09-16 | Samsung Electronics Co., Ltd. | Application layer FEC framework for WiGig |
RU2011134436A (ru) | 2011-08-18 | 2013-10-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") | Способ получения l-аминокислоты с использованием бактерии семейства enterobacteriaceae, обладающей повышенной экспрессией генов каскада образования флагелл и клеточной подвижности |
ES2673582T3 (es) * | 2013-02-08 | 2018-06-22 | Ningxia Eppen Biotech Co. Ltd | Método de generación de L-lisina por medio de bacterias fermentadoras que poseen un gen de aconitasa y/o un elemento regulador modificado |
RU2013118637A (ru) | 2013-04-23 | 2014-10-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") | СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА ENTEROBACTERIACEAE, В КОТОРОЙ РАЗРЕГУЛИРОВАН ГЕН yjjK |
RU2013140115A (ru) | 2013-08-30 | 2015-03-10 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") | СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА Enterobacteriaceae, В КОТОРОЙ НАРУШЕНА ЭКСПРЕССИЯ КЛАСТЕРА ГЕНОВ znuACB |
JP2016192903A (ja) | 2013-09-17 | 2016-11-17 | 味の素株式会社 | 海藻由来バイオマスからのl−アミノ酸の製造方法 |
CN106459857B (zh) | 2013-10-02 | 2019-04-19 | 味之素株式会社 | 氨控制装置及氨控制方法 |
EP2860256B1 (de) | 2013-10-11 | 2017-03-08 | CJ Cheiljedang Corporation | Verfahren zur Herstellung von L-Aminosäuren |
KR101518860B1 (ko) * | 2013-10-11 | 2015-05-12 | 씨제이제일제당 (주) | L-아미노산의 생산 방법 |
RU2014105547A (ru) | 2014-02-14 | 2015-08-20 | Адзиномото Ко., Инк. | СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИИ СЕМЕЙСТВА ENTEROBACTERIACEAE, ИМЕЮЩЕЙ СВЕРХЭКСПРЕССИРУЕМЫЙ ГЕН yajL |
CN104611264B (zh) * | 2015-02-02 | 2017-08-18 | 中国科学院亚热带农业生态研究所 | 一种赖氨酸高产菌株及应用 |
RU2015120052A (ru) | 2015-05-28 | 2016-12-20 | Аджиномото Ко., Инк. | Способ получения L-аминокислоты с использованием бактерии семейства Enterobacteriaceae, в которой ослаблена экспрессия гена gshA |
WO2017146195A1 (en) | 2016-02-25 | 2017-08-31 | Ajinomoto Co., Inc. | A method for producing l-amino acids using a bacterium of the family enterobacteriaceae overexpressing a gene encoding an iron exporter |
JP7491312B2 (ja) | 2018-12-27 | 2024-05-28 | 味の素株式会社 | 腸内細菌科の細菌の発酵による塩基性l-アミノ酸またはその塩の製造方法 |
BR112021014194A2 (pt) | 2019-02-22 | 2021-12-28 | Ajinomoto Kk | Método para a produção de um l-aminoácido |
WO2020204179A1 (en) | 2019-04-05 | 2020-10-08 | Ajinomoto Co., Inc. | Method of producing l-amino acids |
WO2021060438A1 (en) | 2019-09-25 | 2021-04-01 | Ajinomoto Co., Inc. | Method for producing l-amino acids by bacterial fermentation |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5236831A (en) * | 1981-12-29 | 1993-08-17 | Kiowa Hakko Kogyo Co., Ltd. | Amino acid synthesis in corynebacteria using E. coli genes |
US4861722A (en) * | 1983-08-24 | 1989-08-29 | Ajinomoto Company, Inc. | Coryneform bacteria carrying recombinant plasmids and their use in the fermentative production of L-lysine |
JPH0746994B2 (ja) * | 1984-10-04 | 1995-05-24 | 味の素株式会社 | 発酵法によるl−アミノ酸の製造法 |
DE204326T1 (de) * | 1985-06-05 | 1987-07-02 | Kyowa Hakko Kogyo Co., Ltd., Tokio/Tokyo, Jp | Verfahren zur herstellung von l-threonin und l-isoleucin. |
WO1988009819A2 (en) * | 1987-06-12 | 1988-12-15 | Massachusetts Institute Of Technology | C. glutamicum threonine biosynthetic pathway |
US6649379B1 (en) * | 1987-06-12 | 2003-11-18 | Massachusetts Institute Of Technology | Method and deregulated enzyme for threonine production |
DE3908201A1 (de) * | 1989-03-14 | 1990-09-27 | Degussa | Verfahren zur fermentativen herstellung von l-lysin |
US5243039A (en) * | 1989-04-10 | 1993-09-07 | Regents Of The University Of Minnesota | Bacillus MGA3 aspartokinase II gene |
DE3943117A1 (de) * | 1989-12-27 | 1991-07-04 | Forschungszentrum Juelich Gmbh | Verfahren zur fermentativen herstellung von aminosaeure, insbesondere l-lysin, dafuer geeignete mikroorganismen und rekombinante dna |
JPH07108228B2 (ja) * | 1990-10-15 | 1995-11-22 | 味の素株式会社 | 温度感受性プラスミド |
-
1995
- 1995-02-23 JP JP52281395A patent/JP3783065B2/ja not_active Expired - Fee Related
- 1995-02-23 WO PCT/JP1995/000268 patent/WO1995023864A1/ja active IP Right Grant
- 1995-02-23 ES ES95909969T patent/ES2249767T3/es not_active Expired - Lifetime
- 1995-02-23 EP EP95909969A patent/EP0754756B1/de not_active Expired - Lifetime
- 1995-02-23 DE DE69534592T patent/DE69534592T2/de not_active Expired - Lifetime
- 1995-02-23 CN CN95192867A patent/CN1117152C/zh not_active Expired - Fee Related
- 1995-02-23 US US08/700,359 patent/US5766925A/en not_active Expired - Lifetime
- 1995-02-23 DK DK95909969T patent/DK0754756T3/da active
Also Published As
Publication number | Publication date |
---|---|
JP3783065B2 (ja) | 2006-06-07 |
EP0754756B1 (de) | 2005-11-09 |
EP0754756A4 (de) | 1997-12-03 |
ES2249767T3 (es) | 2006-04-01 |
CN1117152C (zh) | 2003-08-06 |
DE69534592T2 (de) | 2006-08-10 |
WO1995023864A1 (fr) | 1995-09-08 |
US5766925A (en) | 1998-06-16 |
DK0754756T3 (da) | 2006-03-13 |
CN1147273A (zh) | 1997-04-09 |
EP0754756A1 (de) | 1997-01-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |