DE69531546D1 - Synthetische gangliosid-derivate - Google Patents

Synthetische gangliosid-derivate

Info

Publication number
DE69531546D1
DE69531546D1 DE69531546T DE69531546T DE69531546D1 DE 69531546 D1 DE69531546 D1 DE 69531546D1 DE 69531546 T DE69531546 T DE 69531546T DE 69531546 T DE69531546 T DE 69531546T DE 69531546 D1 DE69531546 D1 DE 69531546D1
Authority
DE
Germany
Prior art keywords
ganglioside derivatives
synthetic ganglioside
suppressing
immune response
synthetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69531546T
Other languages
English (en)
Other versions
DE69531546T2 (de
Inventor
Stephan Ladisch
Akira Hasegawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of DE69531546D1 publication Critical patent/DE69531546D1/de
Application granted granted Critical
Publication of DE69531546T2 publication Critical patent/DE69531546T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
DE69531546T 1994-09-14 1995-09-14 Synthetische gangliosid-derivate Expired - Lifetime DE69531546T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US305832 1994-09-14
US08/305,832 US5567684A (en) 1994-09-14 1994-09-14 Synthetic ganglioside derivatives
PCT/US1995/011670 WO1996008257A1 (en) 1994-09-14 1995-09-14 Synthetic ganglioside derivatives

Publications (2)

Publication Number Publication Date
DE69531546D1 true DE69531546D1 (de) 2003-09-25
DE69531546T2 DE69531546T2 (de) 2004-06-17

Family

ID=23182557

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69531546T Expired - Lifetime DE69531546T2 (de) 1994-09-14 1995-09-14 Synthetische gangliosid-derivate

Country Status (8)

Country Link
US (1) US5567684A (de)
EP (1) EP0783311B1 (de)
JP (2) JP4727767B2 (de)
AT (1) ATE247475T1 (de)
AU (1) AU3632395A (de)
CA (1) CA2199809C (de)
DE (1) DE69531546T2 (de)
WO (1) WO1996008257A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5936076A (en) * 1991-08-29 1999-08-10 Kirin Beer Kabushiki Kaisha αgalactosylceramide derivatives
EP0666268B1 (de) * 1992-10-22 2000-04-19 Kirin Beer Kabushiki Kaisha Neues sphingolglycolipid und verwendung davon
AU683653B2 (en) * 1993-04-15 1997-11-20 Kirin Pharma Kabushiki Kaisha Novel sphingoglycolipid and use thereof
JPH08176185A (ja) * 1994-12-19 1996-07-09 Toa Boshoku Kk 糖脂質合成中間体
US20030096281A1 (en) * 2001-09-14 2003-05-22 Ganesh Venkataraman Methods of making glycomolecules with enhanced activities and uses thereof
DE10226367A1 (de) * 2002-06-13 2003-12-24 Nutricia Nv Ganglioside mit modifizierter Acylfunktion
PL2137655T3 (pl) 2007-04-16 2012-12-31 Momenta Pharmaceuticals Inc Zdefiniowane produkty glikoproteinowe i powiązane sposoby
BR112012025645A2 (pt) 2010-04-07 2017-12-12 Momenta Pharmaceuticals Inc glicanos de alta manose.
WO2012125553A2 (en) 2011-03-12 2012-09-20 Momenta Pharmaceuticals, Inc. N-acetylhexosamine-containing n-glycans in glycoprotein products
WO2013181575A2 (en) 2012-06-01 2013-12-05 Momenta Pharmaceuticals, Inc. Methods related to denosumab
EP2855533A4 (de) 2013-03-15 2015-11-25 Momenta Pharmaceuticals Inc Verfahren in zusammenhang mit ctla4-fc-fusionsproteinen
ES2708759T3 (es) 2013-05-13 2019-04-11 Momenta Pharmaceuticals Inc Procedimientos para el tratamiento de la neurodegeneración
EP3058084A4 (de) 2013-10-16 2017-07-05 Momenta Pharmaceuticals, Inc. Sialylierte glycoproteine

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4388309A (en) * 1981-06-10 1983-06-14 Shanksville Corporation, N.V. Process for suppressing graft rejection in organ transplantation
JPS59164798A (ja) * 1983-03-09 1984-09-17 Rikagaku Kenkyusho シアル酸含有糖脂質誘導体
IT1212896B (it) * 1983-11-08 1989-11-30 Della Valle Francesco Metodo di somministrazione per via inalatoria di gangliosidi e derivati, e composizioni farmaceutiche relative
IT1199116B (it) * 1984-07-03 1988-12-30 Fidia Farmaceutici Derivati di gangliosidi
IT1208751B (it) * 1986-06-30 1989-07-10 Fidia Farmaceutici Possibile uso dei gangliosidi esogeni in malattie tumorali come fattore protettivo contro la neurotossicita' da farmaci antitumorali
JP2588729B2 (ja) * 1987-10-05 1997-03-12 塩野義製薬株式会社 スフィンゴシン誘導体
JP2782069B2 (ja) * 1988-08-12 1998-07-30 和光純薬工業株式会社 ガングリオシド類の新規な製造法
JPH02307974A (ja) * 1989-05-19 1990-12-21 Nippon Fine Chem Co Ltd セルロース系素材及びその加工品の改質剤
JPH03255028A (ja) * 1990-03-01 1991-11-13 Imeeji Meekaa:Kk 免疫抑制剤
JPH0476082A (ja) * 1990-07-18 1992-03-10 Shiseido Co Ltd ゲル化剤
US5371202A (en) * 1991-02-28 1994-12-06 The Nisshin Oil Mills, Ltd. Processes of preparing sialoglycosyl compounds
JPH04300891A (ja) * 1991-03-29 1992-10-23 Nisshin Oil Mills Ltd:The Ｓ−グリコシドを有するガングリオシド類縁体
WO1992017189A1 (en) * 1991-03-29 1992-10-15 The Regents Of The University Of California Gangliosides with immunosuppressive activity
JPH04353570A (ja) * 1991-05-31 1992-12-08 Asai Bussan Kk 防曇性樹脂組成物、防曇性成形体および防曇方法
WO1993002686A1 (en) * 1991-07-31 1993-02-18 The Regents Of The University Of California Gangliosides with immunosuppressive ceramide moieties
US5399567A (en) * 1993-05-13 1995-03-21 Monsanto Company Method of treating cholera
JPH07228514A (ja) * 1993-12-21 1995-08-29 Nippon Fine Chem Co Ltd 酸化染毛剤組成物

Also Published As

Publication number Publication date
EP0783311A4 (de) 1998-12-23
EP0783311B1 (de) 2003-08-20
ATE247475T1 (de) 2003-09-15
AU3632395A (en) 1996-03-29
DE69531546T2 (de) 2004-06-17
JP2007262085A (ja) 2007-10-11
JPH10508829A (ja) 1998-09-02
CA2199809A1 (en) 1996-03-21
CA2199809C (en) 2008-07-29
JP4727767B2 (ja) 2011-07-20
JP5165283B2 (ja) 2013-03-21
US5567684A (en) 1996-10-22
WO1996008257A1 (en) 1996-03-21
EP0783311A1 (de) 1997-07-16

Similar Documents

Publication Publication Date Title
UA39869C2 (uk) Похідні аспартаму або їх фізіологічно прийнятні солі, спосіб їх отримання та підсолоджувальна композиція
AU580122B2 (en) Block polyesters and like compounds useful as soil release agents in detergent compositions
BG103485A (en) Ketobanzamides as calpain inhibitors
ATE247475T1 (de) Synthetische gangliosid-derivate
CA2109934A1 (en) Substituted indoles as anti-aids pharmaceuticals
ES2132415T3 (es) Nuevos derivados de 5-pirrolil-2-piridilmetilsulfinilbencimidazol.
MX7714E (es) Proceso para la preparacion de un derivado de halodexosisacarosa o galactosacarosa
ATE16488T1 (de) M-4- und isom-4-derivate, ihre herstellung und diese enthaltende zusammensetzungen.
NO173549C (no) Nye organiske forbindelser, fremgangsmaate for fremstilling derav, og anvendelse derav
ES2093099T3 (es) Preparacion de piperidinas sustituidas.
FI881609A0 (fi) Dihydropyridinamider, foerfarande foer deras framstaellning och deras anvaendning i laekemedel.
CA2257479A1 (en) Soap bar composition
DE3070768D1 (en) 1-((substituted-naphthyl)ethyl)-imidazole derivatives, pharmaceutical compositions containing them and methods of making them
DK0623620T3 (da) 5-HT3-pyrrolopyrazinderivater
ES8506011A1 (es) Procedimiento para la obtencion de un derivado de tetrahidrobenzotiazol
ES2058196T3 (es) Derivados de azacromano.
DE3264556D1 (en) Sulfimines, their salts and their preparation, and pharmaceutical compositions containing them
FI960588A (fi) Mikrobisideina käytettäviä tiokarbamoyyliyhdisteitä
ES2023760A6 (es) Procedimiento para la preparacion de derivados benzotiazinicos.
DK0485894T3 (da) Fremgangsmåde til fremstilling af semisyntetiske diastereomerrene N-glycidyl-anthracycliner
IT1237506B (it) Derivati amminici di 2,3-diaza-antracene-9,10-dioni come farmaci antitumorali
FI922518A (fi) Menetelmä farmaseuttisesti käyttökelpoisten pilokarpiinijohdannaisten valmistamiseksi

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee
8370 Indication related to discontinuation of the patent is to be deleted