IT1237506B - Derivati amminici di 2,3-diaza-antracene-9,10-dioni come farmaci antitumorali - Google Patents

Derivati amminici di 2,3-diaza-antracene-9,10-dioni come farmaci antitumorali

Info

Publication number
IT1237506B
IT1237506B IT02217589A IT2217589A IT1237506B IT 1237506 B IT1237506 B IT 1237506B IT 02217589 A IT02217589 A IT 02217589A IT 2217589 A IT2217589 A IT 2217589A IT 1237506 B IT1237506 B IT 1237506B
Authority
IT
Italy
Prior art keywords
dion
diaza
anthracene
cancer drugs
compounds
Prior art date
Application number
IT02217589A
Other languages
English (en)
Other versions
IT8922175A0 (it
IT8922175A1 (it
Inventor
Carmelo A Gandolfi
Ernesto Menta
Silvano Spinelli
Sergio Tognella
Original Assignee
Boehringer Biochemia Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Biochemia Srl filed Critical Boehringer Biochemia Srl
Publication of IT8922175A0 publication Critical patent/IT8922175A0/it
Priority to IT02217589A priority Critical patent/IT1237506B/it
Priority to JP2514412A priority patent/JPH05504124A/ja
Priority to AT90915454T priority patent/ATE124402T1/de
Priority to EP90915454A priority patent/EP0497809B1/en
Priority to ES90915454T priority patent/ES2075222T3/es
Priority to AU65481/90A priority patent/AU6548190A/en
Priority to PCT/EP1990/001794 priority patent/WO1991006540A1/en
Priority to DE69020576T priority patent/DE69020576T2/de
Priority to US07/602,526 priority patent/US5162320A/en
Publication of IT8922175A1 publication Critical patent/IT8922175A1/it
Application granted granted Critical
Publication of IT1237506B publication Critical patent/IT1237506B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Luminescent Compositions (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
IT02217589A 1989-10-27 1989-10-27 Derivati amminici di 2,3-diaza-antracene-9,10-dioni come farmaci antitumorali IT1237506B (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IT02217589A IT1237506B (it) 1989-10-27 1989-10-27 Derivati amminici di 2,3-diaza-antracene-9,10-dioni come farmaci antitumorali
ES90915454T ES2075222T3 (es) 1989-10-27 1990-10-23 1,4-bis(alquilamino)-2,3-diaza-antraceno-9,10-dionas.
AT90915454T ATE124402T1 (de) 1989-10-27 1990-10-23 1,4-bis(alkylamino)-2,3-diaza-anthracen-9,10- dione.
EP90915454A EP0497809B1 (en) 1989-10-27 1990-10-23 1,4-bis(alkylamino)-2,3-diaza-anthracene-9,10-diones
JP2514412A JPH05504124A (ja) 1989-10-27 1990-10-23 １，４―ビス（アルキルアミノ）―２，３―ジアザ―アントラセン―９，１０―ジオン類
AU65481/90A AU6548190A (en) 1989-10-27 1990-10-23 1,4-bis(alkylamino)-2,3-diaza-anthracene-9,10-diones
PCT/EP1990/001794 WO1991006540A1 (en) 1989-10-27 1990-10-23 1,4-bis(alkylamino)-2,3-diaza-anthracene-9,10-diones
DE69020576T DE69020576T2 (de) 1989-10-27 1990-10-23 1,4-bis(alkylamino)-2,3-diaza-anthracen-9,10-dione.
US07/602,526 US5162320A (en) 1989-10-27 1990-10-25 1,4-bis(alkylamino)-2,3-diaza-anthracene-9,10-diones

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT02217589A IT1237506B (it) 1989-10-27 1989-10-27 Derivati amminici di 2,3-diaza-antracene-9,10-dioni come farmaci antitumorali

Publications (3)

Publication Number Publication Date
IT8922175A0 IT8922175A0 (it) 1989-10-27
IT8922175A1 IT8922175A1 (it) 1991-04-27
IT1237506B true IT1237506B (it) 1993-06-08

Family

ID=11192611

Family Applications (1)

Application Number Title Priority Date Filing Date
IT02217589A IT1237506B (it) 1989-10-27 1989-10-27 Derivati amminici di 2,3-diaza-antracene-9,10-dioni come farmaci antitumorali

Country Status (9)

Country Link
US (1) US5162320A (it)
EP (1) EP0497809B1 (it)
JP (1) JPH05504124A (it)
AT (1) ATE124402T1 (it)
AU (1) AU6548190A (it)
DE (1) DE69020576T2 (it)
ES (1) ES2075222T3 (it)
IT (1) IT1237506B (it)
WO (1) WO1991006540A1 (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5719282A (en) * 1989-05-19 1998-02-17 Consejo Superior De Investigaciones Cientificas 1,4-bis(amino) benzo g!phthalazine compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE687916A (it) * 1965-10-12 1967-03-16
US3880881A (en) * 1971-08-03 1975-04-29 American Cyanamid Co Azomethinimine dyes
US4428882A (en) * 1979-05-29 1984-01-31 American Cyanamid Company 1-(Aminoalkylamino)-5,8-dihydroxy-4-substituted-anthraquinones
US4275009A (en) * 1979-05-29 1981-06-23 American Cyanamid Company 1-(Aminoalkylamino)-5,8-dihydroxy-4-substituted-anthraquinones
US4278605A (en) * 1980-06-30 1981-07-14 American Cyanamid Company Heteroalkylenebisanthraquinones

Also Published As

Publication number Publication date
US5162320A (en) 1992-11-10
EP0497809B1 (en) 1995-06-28
WO1991006540A1 (en) 1991-05-16
ATE124402T1 (de) 1995-07-15
JPH05504124A (ja) 1993-07-01
ES2075222T3 (es) 1995-10-01
IT8922175A0 (it) 1989-10-27
EP0497809A1 (en) 1992-08-12
DE69020576T2 (de) 1996-01-18
AU6548190A (en) 1991-05-31
IT8922175A1 (it) 1991-04-27
DE69020576D1 (de) 1995-08-03

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971030