ATE247475T1 - Synthetische gangliosid-derivate - Google Patents

Synthetische gangliosid-derivate

Info

Publication number
ATE247475T1
ATE247475T1 AT95933807T AT95933807T ATE247475T1 AT E247475 T1 ATE247475 T1 AT E247475T1 AT 95933807 T AT95933807 T AT 95933807T AT 95933807 T AT95933807 T AT 95933807T AT E247475 T1 ATE247475 T1 AT E247475T1
Authority
AT
Austria
Prior art keywords
ganglioside derivatives
synthetic ganglioside
suppressing
immune response
synthetic
Prior art date
Application number
AT95933807T
Other languages
English (en)
Inventor
Stephan Ladisch
Akira Hasegawa
Original Assignee
Stephan Ladisch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stephan Ladisch filed Critical Stephan Ladisch
Application granted granted Critical
Publication of ATE247475T1 publication Critical patent/ATE247475T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
AT95933807T 1994-09-14 1995-09-14 Synthetische gangliosid-derivate ATE247475T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/305,832 US5567684A (en) 1994-09-14 1994-09-14 Synthetic ganglioside derivatives
PCT/US1995/011670 WO1996008257A1 (en) 1994-09-14 1995-09-14 Synthetic ganglioside derivatives

Publications (1)

Publication Number Publication Date
ATE247475T1 true ATE247475T1 (de) 2003-09-15

Family

ID=23182557

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95933807T ATE247475T1 (de) 1994-09-14 1995-09-14 Synthetische gangliosid-derivate

Country Status (8)

Country Link
US (1) US5567684A (de)
EP (1) EP0783311B1 (de)
JP (2) JP4727767B2 (de)
AT (1) ATE247475T1 (de)
AU (1) AU3632395A (de)
CA (1) CA2199809C (de)
DE (1) DE69531546T2 (de)
WO (1) WO1996008257A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5936076A (en) * 1991-08-29 1999-08-10 Kirin Beer Kabushiki Kaisha αgalactosylceramide derivatives
CA2147629C (en) * 1992-10-22 2005-03-22 Koji Akimoto Novel sphingoglycolipids and the use thereof
JP4020958B2 (ja) * 1993-04-15 2007-12-12 キリンファーマ株式会社 新規スフィンゴ糖脂質およびその使用
JPH08176185A (ja) * 1994-12-19 1996-07-09 Toa Boshoku Kk 糖脂質合成中間体
EP1438387A4 (de) * 2001-09-14 2004-10-13 Momenta Pharmaceuticals Inc Verfahren zur herstellung von glycomolekülen mit verstärkten aktivitäten und verwendungen davon
DE10226367A1 (de) * 2002-06-13 2003-12-24 Nutricia Nv Ganglioside mit modifizierter Acylfunktion
US20100113294A1 (en) 2007-04-16 2010-05-06 Momenta Pharmaceuticals, Inc. Defined glycoprotein products and related methods
AU2011237442A1 (en) 2010-04-07 2012-10-18 Momenta Pharmaceuticals, Inc. High mannose glycans
US9170249B2 (en) 2011-03-12 2015-10-27 Momenta Pharmaceuticals, Inc. N-acetylhexosamine-containing N-glycans in glycoprotein products
US9695244B2 (en) 2012-06-01 2017-07-04 Momenta Pharmaceuticals, Inc. Methods related to denosumab
EP2855533A4 (de) 2013-03-15 2015-11-25 Momenta Pharmaceuticals Inc Verfahren in zusammenhang mit ctla4-fc-fusionsproteinen
ES2708759T3 (es) 2013-05-13 2019-04-11 Momenta Pharmaceuticals Inc Procedimientos para el tratamiento de la neurodegeneración
WO2015057622A1 (en) 2013-10-16 2015-04-23 Momenta Pharmaceuticals, Inc. Sialylated glycoproteins

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4388309A (en) * 1981-06-10 1983-06-14 Shanksville Corporation, N.V. Process for suppressing graft rejection in organ transplantation
JPS59164798A (ja) * 1983-03-09 1984-09-17 Rikagaku Kenkyusho シアル酸含有糖脂質誘導体
IT1212896B (it) * 1983-11-08 1989-11-30 Della Valle Francesco Metodo di somministrazione per via inalatoria di gangliosidi e derivati, e composizioni farmaceutiche relative
IT1199116B (it) * 1984-07-03 1988-12-30 Fidia Farmaceutici Derivati di gangliosidi
IT1208751B (it) * 1986-06-30 1989-07-10 Fidia Farmaceutici Possibile uso dei gangliosidi esogeni in malattie tumorali come fattore protettivo contro la neurotossicita' da farmaci antitumorali
JP2588729B2 (ja) * 1987-10-05 1997-03-12 塩野義製薬株式会社 スフィンゴシン誘導体
JP2782069B2 (ja) * 1988-08-12 1998-07-30 和光純薬工業株式会社 ガングリオシド類の新規な製造法
JPH02307974A (ja) * 1989-05-19 1990-12-21 Nippon Fine Chem Co Ltd セルロース系素材及びその加工品の改質剤
JPH03255028A (ja) * 1990-03-01 1991-11-13 Imeeji Meekaa:Kk 免疫抑制剤
JPH0476082A (ja) * 1990-07-18 1992-03-10 Shiseido Co Ltd ゲル化剤
US5371202A (en) * 1991-02-28 1994-12-06 The Nisshin Oil Mills, Ltd. Processes of preparing sialoglycosyl compounds
JPH04300891A (ja) * 1991-03-29 1992-10-23 Nisshin Oil Mills Ltd:The Ｓ−グリコシドを有するガングリオシド類縁体
WO1992017189A1 (en) * 1991-03-29 1992-10-15 The Regents Of The University Of California Gangliosides with immunosuppressive activity
JPH04353570A (ja) * 1991-05-31 1992-12-08 Asai Bussan Kk 防曇性樹脂組成物、防曇性成形体および防曇方法
WO1993002686A1 (en) * 1991-07-31 1993-02-18 The Regents Of The University Of California Gangliosides with immunosuppressive ceramide moieties
US5399567A (en) * 1993-05-13 1995-03-21 Monsanto Company Method of treating cholera
JPH07228514A (ja) * 1993-12-21 1995-08-29 Nippon Fine Chem Co Ltd 酸化染毛剤組成物

Also Published As

Publication number Publication date
CA2199809C (en) 2008-07-29
WO1996008257A1 (en) 1996-03-21
JP2007262085A (ja) 2007-10-11
DE69531546T2 (de) 2004-06-17
AU3632395A (en) 1996-03-29
JP5165283B2 (ja) 2013-03-21
JP4727767B2 (ja) 2011-07-20
US5567684A (en) 1996-10-22
EP0783311B1 (de) 2003-08-20
CA2199809A1 (en) 1996-03-21
JPH10508829A (ja) 1998-09-02
EP0783311A4 (de) 1998-12-23
DE69531546D1 (de) 2003-09-25
EP0783311A1 (de) 1997-07-16

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties