DE69422061D1 - 3-phenyl-2-isoxazoline derivate als entzündugshemmende mittel - Google Patents

3-phenyl-2-isoxazoline derivate als entzündugshemmende mittel

Info

Publication number
DE69422061D1
DE69422061D1 DE69422061T DE69422061T DE69422061D1 DE 69422061 D1 DE69422061 D1 DE 69422061D1 DE 69422061 T DE69422061 T DE 69422061T DE 69422061 T DE69422061 T DE 69422061T DE 69422061 D1 DE69422061 D1 DE 69422061D1
Authority
DE
Germany
Prior art keywords
pct
date
inflammatory
phenyl
resistant agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69422061T
Other languages
English (en)
Other versions
DE69422061T2 (de
Inventor
Edward Kleinman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of DE69422061D1 publication Critical patent/DE69422061D1/de
Publication of DE69422061T2 publication Critical patent/DE69422061T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07F9/653—Five-membered rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DE69422061T 1993-11-26 1994-10-12 3-phenyl-2-isoxazoline derivate als entzündugshemmende mittel Expired - Fee Related DE69422061T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15724193A 1993-11-26 1993-11-26
PCT/IB1994/000313 WO1995014680A1 (en) 1993-11-26 1994-10-12 3-aryl-2-isoxazolines as antiinflammatory agents

Publications (2)

Publication Number Publication Date
DE69422061D1 true DE69422061D1 (de) 2000-01-13
DE69422061T2 DE69422061T2 (de) 2000-03-30

Family

ID=22562909

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69422061T Expired - Fee Related DE69422061T2 (de) 1993-11-26 1994-10-12 3-phenyl-2-isoxazoline derivate als entzündugshemmende mittel

Country Status (12)

Country Link
US (1) US5686434A (de)
EP (1) EP0730587B1 (de)
JP (1) JP2818820B2 (de)
AT (1) ATE187447T1 (de)
CA (1) CA2177375A1 (de)
DE (1) DE69422061T2 (de)
DK (1) DK0730587T3 (de)
ES (1) ES2139754T3 (de)
FI (1) FI945556A (de)
GR (1) GR3032506T3 (de)
PT (1) PT730587E (de)
WO (1) WO1995014680A1 (de)

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US6022977A (en) 1997-03-26 2000-02-08 Dupont Pharmaceuticals Company Dynamic resolution of isoxazoline thioesters to isoxazoline carboxylic acids
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DE19852095A1 (de) 1998-11-12 2000-05-18 Basf Ag Verfahren zur Herstellung von 2-Alkyl-3-(4,5-dihydroisoxazol-3-yl)-acylbenzolen
CZ299064B6 (cs) * 1998-05-11 2008-04-16 Basf Aktiengesellschaft Zpusob výroby isoxazolu
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JP5038568B2 (ja) 1999-08-21 2012-10-03 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 協力剤の組合せ物
KR100399361B1 (ko) 1999-11-04 2003-09-26 주식회사 엘지생명과학 캐스파제 억제제 함유 치료제 조성물
JP4195561B2 (ja) * 1999-09-17 2008-12-10 エルジー ケム インヴェストメント リミティッド カスパーゼインヒビター
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Also Published As

Publication number Publication date
ATE187447T1 (de) 1999-12-15
JP2818820B2 (ja) 1998-10-30
EP0730587B1 (de) 1999-12-08
FI945556A (fi) 1995-05-27
GR3032506T3 (en) 2000-05-31
DK0730587T3 (da) 2000-04-10
WO1995014680A1 (en) 1995-06-01
EP0730587A1 (de) 1996-09-11
FI945556A0 (fi) 1994-11-25
US5686434A (en) 1997-11-11
ES2139754T3 (es) 2000-02-16
JPH09500146A (ja) 1997-01-07
DE69422061T2 (de) 2000-03-30
CA2177375A1 (en) 1995-06-01
PT730587E (pt) 2000-05-31

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