DE69332292D1 - Pyran-2-onen und 5,6-dihydropyran-2-onen verwendbar für die behandlung von hiv und anderen tetroviren - Google Patents
Pyran-2-onen und 5,6-dihydropyran-2-onen verwendbar für die behandlung von hiv und anderen tetrovirenInfo
- Publication number
- DE69332292D1 DE69332292D1 DE69332292T DE69332292T DE69332292D1 DE 69332292 D1 DE69332292 D1 DE 69332292D1 DE 69332292 T DE69332292 T DE 69332292T DE 69332292 T DE69332292 T DE 69332292T DE 69332292 D1 DE69332292 D1 DE 69332292D1
- Authority
- DE
- Germany
- Prior art keywords
- ones
- pyran
- tetrovirus
- dihydropyran
- hiv
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Cosmetics (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US97534392A | 1992-11-13 | 1992-11-13 | |
US9087693A | 1993-07-13 | 1993-07-13 | |
US13064193A | 1993-10-01 | 1993-10-01 | |
PCT/US1993/010645 WO1994011361A1 (en) | 1992-11-13 | 1993-11-09 | Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating hiv and other retroviruses |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69332292D1 true DE69332292D1 (de) | 2002-10-17 |
DE69332292T2 DE69332292T2 (de) | 2003-05-28 |
Family
ID=27376682
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69333771T Expired - Lifetime DE69333771T2 (de) | 1992-11-13 | 1993-11-09 | Pyran-2-onen und 5,6-dihydropyran-2-onen brauchbar für die Behandlung von Hyperplasie und andere Krankheiten |
DE69332292T Expired - Lifetime DE69332292T2 (de) | 1992-11-13 | 1993-11-09 | Pyran-2-onen und 5,6-dihydropyran-2-onen verwendbar für die behandlung von hiv und anderen tetroviren |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69333771T Expired - Lifetime DE69333771T2 (de) | 1992-11-13 | 1993-11-09 | Pyran-2-onen und 5,6-dihydropyran-2-onen brauchbar für die Behandlung von Hyperplasie und andere Krankheiten |
Country Status (26)
Country | Link |
---|---|
EP (2) | EP1203770B1 (de) |
JP (1) | JP3583127B2 (de) |
KR (1) | KR100314975B1 (de) |
CN (1) | CN1040321C (de) |
AT (2) | ATE290531T1 (de) |
AU (1) | AU687368B2 (de) |
BR (1) | BR9307451A (de) |
CA (1) | CA2145661C (de) |
CZ (1) | CZ291853B6 (de) |
DE (2) | DE69333771T2 (de) |
DK (2) | DK1203770T3 (de) |
ES (2) | ES2182837T3 (de) |
FI (1) | FI120399B (de) |
GE (1) | GEP20094660B (de) |
HU (1) | HU228126B1 (de) |
IL (1) | IL107556A (de) |
LV (1) | LV13088B (de) |
MY (1) | MY119031A (de) |
NO (1) | NO319914B1 (de) |
NZ (1) | NZ258013A (de) |
PL (1) | PL178653B1 (de) |
PT (2) | PT668860E (de) |
RU (1) | RU2134691C1 (de) |
SK (1) | SK285001B6 (de) |
WO (1) | WO1994011361A1 (de) |
ZA (1) | ZA938019B (de) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0720607A1 (de) * | 1993-09-17 | 1996-07-10 | PHARMACIA & UPJOHN COMPANY | Substituierte tetronsäuren zur behandlung von hiv und anderen retroviren |
US6005103A (en) * | 1993-11-19 | 1999-12-21 | Warner-Lambert Company | Pyrone derivatives as protease inhibitors and antiviral agents |
ATE263761T1 (de) * | 1993-11-19 | 2004-04-15 | Parke Davis & Co | 5,6-dihydropyronderivate als proteaseinhibitoren und antiviralmittel |
US5840751A (en) * | 1993-11-19 | 1998-11-24 | Warner-Lambert Company | 5,6-dihydropyrone derivatives as protease inhibitors and antiviral agents |
SI0729463T1 (en) * | 1993-11-19 | 2002-08-31 | Parke Davis & Company | 5,6-dihydropyrone derivatives as protease inhibitors and antiviral agents |
DE69432056T2 (de) * | 1993-11-19 | 2003-10-09 | Parke Davis & Co | Pyron derivate als protease inhibitoren und antivirusmitteln |
AU682417B2 (en) * | 1993-11-19 | 1997-10-02 | Parke, Davis & Company | Pyrone derivatives as protease inhibitors and antiviral agents |
IL129871A (en) * | 1994-05-06 | 2003-11-23 | Pharmacia & Upjohn Inc | Process for preparing 4-phenyl-substituted octanoyl-oxazolidin-2-one intermediates that are useful for preparing pyran-2-ones useful for treating retroviral infections |
DE69626276T2 (de) * | 1995-03-20 | 2003-11-13 | Upjohn Co | Tetronsäurederivate zur behandlung von hiv- und anderen retroviruserkrankungen |
DK0909184T3 (da) * | 1996-07-03 | 2003-12-22 | Upjohn Co | Målrettet lægemiddelindgivelse ved anvendelse af sulfonamidderivater |
CN1298714C (zh) * | 1997-09-11 | 2007-02-07 | 法玛西雅厄普约翰美国公司 | 制备作为蛋白酶抑制剂的4-羟基-2-氧-吡喃衍生物的新方法 |
DE69917237T2 (de) | 1998-03-12 | 2005-05-04 | Teijin Ltd. | Benzofurylpyron-derivate |
EP1281399A3 (de) * | 2001-08-01 | 2004-02-11 | Warner-Lambert Company | Hemmer mit doppelter Wirkung auf Wachsester- und Cholesterylestersynthese zur Hemmung der Sebumproduktion |
DOP2003000641A (es) | 2002-05-10 | 2003-11-15 | Pfizer | Inhibidores de las arn polimerasa dependiente de arn del virus de las hepatitis c y composiciones y tratamiento que los usan |
CN102030645A (zh) | 2003-10-24 | 2011-04-27 | 隆萨股份公司 | 6,6,6-三卤-3,5-二氧代己酸酯的制备方法 |
UA97369C2 (ru) * | 2006-06-16 | 2012-02-10 | Фарма Мар, С.А. | Противоопухолевые соединения дигидропиран-2-она и фармацевтическая композиция на их основе |
UA106967C2 (uk) | 2007-12-20 | 2014-11-10 | Фарма Мар, С.А. | Протипухлинні аналоги пептидів, фармацевтична композиція, спосіб одержання сполук та проміжні сполуки |
US9139714B2 (en) | 2008-11-05 | 2015-09-22 | Clariant Finance (Bvi) Limited | Method for producing dialkylphosphinic acids and esters and salts thereof by means of allyl alcohols-acroleins and use thereof |
DE102008055914A1 (de) | 2008-11-05 | 2010-05-06 | Clariant International Limited | Verfahren zur Herstellung von mono-hydroxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Acroleinen und ihre Verwendung |
DE102008055916A1 (de) | 2008-11-05 | 2010-05-06 | Clariant International Limited | Verfahren zur Herstellung von mono-hydroxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Allylalkoholen und ihre Verwendung |
DE102008056339A1 (de) | 2008-11-07 | 2010-05-12 | Clariant International Limited | Verfahren zur Herstellung von mono-aminofunktionalisierten Dialkylphosphinsäuren, -estern und -salzen und ihre Verwendung |
DE102008056341A1 (de) | 2008-11-07 | 2010-05-12 | Clariant International Limited | Verfahren zur Herstellung von monoaminofunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Acrylnitrilen und ihre Verwendung |
US8664418B2 (en) | 2008-11-07 | 2014-03-04 | Clariant Finance (Bvi) Limited | Method for producing dialkylphosphinic acids and esters and salts thereof by means of acrylic acid derivatives and use thereof |
DE102008056342A1 (de) | 2008-11-07 | 2010-05-12 | Clariant International Limited | Verfahren zur Herstellung von Dialkylphosphinsäuren, -estern und -salzen mittels Acrylnitrilen und ihre Verwendung |
EP2367835B1 (de) | 2008-11-11 | 2013-12-11 | Clariant Finance (BVI) Limited | Verfahren zur herstellung von mono-allylfunktionalisierten dialkylphosphinsäuren, deren salze und ester mit allylischen verbindungen und ihre verwendung |
DE102008060035A1 (de) | 2008-12-02 | 2010-06-10 | Clariant International Limited | Verfahren zur Herstellung von mono-hydroxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Vinylester einer Carbonsäure und ihre Verwendung |
DE102008060036A1 (de) | 2008-12-02 | 2010-06-10 | Clariant International Limited | Verfahren zur Herstellung von mono-carboxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Vinylester einer Carbonsäure und ihre Verwendung |
DE102008060535A1 (de) | 2008-12-04 | 2010-06-10 | Clariant International Limited | Verfahren zur Herstellung von mono-carboxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Vinylether und ihre Verwendung |
DE102008063642A1 (de) | 2008-12-18 | 2010-06-24 | Clariant International Limited | Verfahren zur Herstellung von monocarboxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Alkylenoxiden und ihre Verwendung |
DE102008063668A1 (de) | 2008-12-18 | 2010-07-01 | Clariant International Limited | Verfahren zur Herstellung von Alkylphosponsäuren, -estern und -salzen mittels Oxidation von Alkylphosphonigsäuren und ihre Verwendung |
DE102008063627A1 (de) | 2008-12-18 | 2010-06-24 | Clariant International Limited | Verfahren zur Herstellung von monohydroxyfunktionalisierten Dialkylphosphinsäuren,-estern und -salzen mittels Ethylenoxid und ihre Verwendung |
CN102164931B (zh) | 2008-12-18 | 2015-07-22 | 科莱恩金融(Bvi)有限公司 | 利用乙炔制备亚乙基二烷基次膦酸、亚乙基二烷基次膦酸酯和亚乙基二烷基次膦酸盐的方法,以及它们的用途 |
DE102008064012A1 (de) | 2008-12-19 | 2010-06-24 | Clariant International Limited | Halogenfreie Addukte von Alkylphosphonigsäurederivaten und diesterbildenden Olefinen, halogenfreie Verfahren zu deren Herstellung und ihre Verwendung |
DE102008064003A1 (de) | 2008-12-19 | 2010-06-24 | Clariant International Limited | Verfahren zur Herstellung von mono-funktionalisierten Dialkylphosphinsäuren, -estern und -salzen und ihre Verwendung |
US20120202814A1 (en) * | 2009-10-02 | 2012-08-09 | Università Degli Studi Di Siena | Compounds with ddx3 inhibitory activity and uses thereof |
CN102690275A (zh) * | 2011-03-25 | 2012-09-26 | 中国人民解放军第二军医大学 | 四氢呋喃并[3,4-c]吡喃酮类化合物及其制备方法和用途 |
CN103044375B (zh) * | 2012-12-02 | 2015-08-12 | 大理学院 | 一种二氢吡喃酮化合物及其制备方法和药物用途 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1276654A (fr) * | 1958-10-01 | 1961-11-24 | Nouveaux dérivés de l'hydroxy-4-alpha-2-pyrone | |
FR1276645A (fr) * | 1959-12-28 | 1961-11-17 | Wild Heerbrugg Ag | Objectif de microscope |
JPH03503635A (ja) * | 1988-03-01 | 1991-08-15 | ジ・アップジョン・カンパニー | ヒトにおいて逆転写酵素を抑制するクマリン類 |
-
1993
- 1993-10-27 ZA ZA938019A patent/ZA938019B/xx unknown
- 1993-11-09 DE DE69333771T patent/DE69333771T2/de not_active Expired - Lifetime
- 1993-11-09 DK DK02002073T patent/DK1203770T3/da active
- 1993-11-09 SK SK616-95A patent/SK285001B6/sk not_active IP Right Cessation
- 1993-11-09 JP JP51221794A patent/JP3583127B2/ja not_active Expired - Lifetime
- 1993-11-09 DK DK94900546T patent/DK0668860T3/da active
- 1993-11-09 PL PL93308998A patent/PL178653B1/pl unknown
- 1993-11-09 AT AT02002073T patent/ATE290531T1/de active
- 1993-11-09 AU AU55493/94A patent/AU687368B2/en not_active Expired
- 1993-11-09 MY MYPI93002343A patent/MY119031A/en unknown
- 1993-11-09 AT AT94900546T patent/ATE223910T1/de active
- 1993-11-09 WO PCT/US1993/010645 patent/WO1994011361A1/en active IP Right Grant
- 1993-11-09 RU RU95112465A patent/RU2134691C1/ru active
- 1993-11-09 KR KR1019950701926A patent/KR100314975B1/ko not_active IP Right Cessation
- 1993-11-09 EP EP02002073A patent/EP1203770B1/de not_active Expired - Lifetime
- 1993-11-09 PT PT94900546T patent/PT668860E/pt unknown
- 1993-11-09 EP EP94900546A patent/EP0668860B1/de not_active Expired - Lifetime
- 1993-11-09 DE DE69332292T patent/DE69332292T2/de not_active Expired - Lifetime
- 1993-11-09 HU HU9501411A patent/HU228126B1/hu unknown
- 1993-11-09 NZ NZ258013A patent/NZ258013A/en not_active IP Right Cessation
- 1993-11-09 CA CA002145661A patent/CA2145661C/en not_active Expired - Lifetime
- 1993-11-09 ES ES94900546T patent/ES2182837T3/es not_active Expired - Lifetime
- 1993-11-09 CZ CZ19951078A patent/CZ291853B6/cs not_active IP Right Cessation
- 1993-11-09 BR BR9307451-4A patent/BR9307451A/pt not_active IP Right Cessation
- 1993-11-09 ES ES02002073T patent/ES2237624T3/es not_active Expired - Lifetime
- 1993-11-09 PT PT02002073T patent/PT1203770E/pt unknown
- 1993-11-10 IL IL10755693A patent/IL107556A/en not_active IP Right Cessation
- 1993-11-12 CN CN93114470A patent/CN1040321C/zh not_active Expired - Lifetime
-
1995
- 1995-05-11 FI FI952302A patent/FI120399B/fi not_active IP Right Cessation
- 1995-05-12 NO NO19951899A patent/NO319914B1/no not_active IP Right Cessation
-
2003
- 2003-09-11 LV LVP-03-101A patent/LV13088B/en unknown
-
2008
- 2008-05-06 GE GEAP200810686A patent/GEP20094660B/en unknown
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