DE69324006D1 - Zubereitungen von hyaluronsaeure mit niedrigem molekulargewicht zur foerderung der knochenbildung - Google Patents

Zubereitungen von hyaluronsaeure mit niedrigem molekulargewicht zur foerderung der knochenbildung

Info

Publication number
DE69324006D1
DE69324006D1 DE69324006T DE69324006T DE69324006D1 DE 69324006 D1 DE69324006 D1 DE 69324006D1 DE 69324006 T DE69324006 T DE 69324006T DE 69324006 T DE69324006 T DE 69324006T DE 69324006 D1 DE69324006 D1 DE 69324006D1
Authority
DE
Germany
Prior art keywords
hyaluronic acid
pct
preparations
molecular weight
low molecular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69324006T
Other languages
English (en)
Other versions
DE69324006T2 (de
Inventor
Lanfranco Callegaro
Aurelio Romeo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fidia Farmaceutici SpA
Original Assignee
Fidia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia SpA filed Critical Fidia SpA
Application granted granted Critical
Publication of DE69324006D1 publication Critical patent/DE69324006D1/de
Publication of DE69324006T2 publication Critical patent/DE69324006T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Materials For Medical Uses (AREA)
DE69324006T 1992-04-17 1993-04-16 Zubereitungen von hyaluronsaeure mit niedrigem molekulargewicht zur foerderung der knochenbildung Expired - Lifetime DE69324006T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITPD920071A IT1260148B (it) 1992-04-17 1992-04-17 Impiego di preparazioni di acido ialuronico per la formazione di tessuto osseo
PCT/EP1993/000932 WO1993020827A1 (en) 1992-04-17 1993-04-16 Preparations of low molecular weight hyaluronic acid for stimulating bone formation

Publications (2)

Publication Number Publication Date
DE69324006D1 true DE69324006D1 (de) 1999-04-22
DE69324006T2 DE69324006T2 (de) 1999-11-11

Family

ID=11389901

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69324006T Expired - Lifetime DE69324006T2 (de) 1992-04-17 1993-04-16 Zubereitungen von hyaluronsaeure mit niedrigem molekulargewicht zur foerderung der knochenbildung

Country Status (11)

Country Link
US (1) US5646129A (de)
EP (1) EP0637245B1 (de)
JP (1) JP3333205B2 (de)
KR (1) KR100310277B1 (de)
AT (1) ATE177641T1 (de)
AU (1) AU677189B2 (de)
CA (1) CA2118219C (de)
DE (1) DE69324006T2 (de)
ES (1) ES2130268T3 (de)
IT (1) IT1260148B (de)
WO (1) WO1993020827A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995001181A1 (en) * 1993-07-01 1995-01-12 Allelix Biopharmaceuticals Inc. Hyaluronic acid fragments and their therapeutic use
IT1282219B1 (it) * 1995-12-20 1998-03-16 Fidia Advanced Biopolymers Srl Processo chimico fisico combinato per la preparazione di frazioni di acido ialuronico a basso peso molecolare caratterizzate da bassa
US6875753B1 (en) * 1996-03-14 2005-04-05 The Governors Of The University Of Alberta Methods for cell mobilization using in vivo treatment with hyaluronan (HA)
US20050113335A1 (en) * 1996-04-02 2005-05-26 Pilarski Linda M. Methods for cell mobilization using in vivo treatment with hyaluronan (HA)
US5939047A (en) * 1996-04-16 1999-08-17 Jernberg; Gary R. Local delivery of chemotherapeutic agents for treatment of periodontal disease
US6872819B1 (en) 1998-05-27 2005-03-29 Fidia Advanced Biopolymers S.R.L. Biomaterials containing hyaluronic acid derivatives in the form of three-dimensional structures free from cellular components or products thereof for the in vivo regeneration of tissue cells
JP3032824B1 (ja) * 1999-01-28 2000-04-17 東京医科歯科大学長 骨誘導促進剤
AU770196B2 (en) * 1999-02-04 2004-02-12 Warsaw Orthopedic, Inc. Osteogenic paste compositions and uses thereof
IT1306644B1 (it) 1999-04-08 2001-10-02 Fidia Advanced Biopolymers Srl Strutture tridimensionali comprendenti derivati dell'acido ialuronicoottenibili mediante la tecnica antisolvente supercritico.
US6726898B2 (en) 2000-11-17 2004-04-27 Gary R. Jernberg Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease
US6576226B1 (en) 2000-11-17 2003-06-10 Gary R. Jernberg Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease
JP2004250592A (ja) * 2003-02-20 2004-09-09 Seikagaku Kogyo Co Ltd 紫外線照射による低分子化グリコサミノグリカンの製造方法
US20040180025A1 (en) * 2003-03-12 2004-09-16 New Life Resources, Llc Therapeutic, nutraceutical and cosmetic applications for eggshell membrane and processed eggshell membrane preparations
US6946551B2 (en) * 2003-03-12 2005-09-20 New Life Resources, Llc Preparation of hyaluronic acid from eggshell membrane
US20080063677A1 (en) * 2004-03-10 2008-03-13 New Life Resources, Llc Therapeutic, nutraceutical and cosmetic applications for eggshell membrane and processed eggshell membrane preparations
US8580315B2 (en) * 2004-03-10 2013-11-12 Esm Technologies, Llc Anti-inflammatory activity of eggshell membrane and processed eggshell membrane preparations
US20050226936A1 (en) 2004-04-08 2005-10-13 Q-Med Ab Method of soft tissue augmentation
US20100075921A1 (en) * 2005-02-15 2010-03-25 Ahmad Alkayali Prêparation of hyaluronic acid with desired low molecular weight as a food supplement
US20060183709A1 (en) * 2005-02-15 2006-08-17 Ahmad Alkayali Preparation of low molecular weight hyaluronic acid as a food supplement
US20070099867A1 (en) * 2005-05-24 2007-05-03 Glycoscience Laboratories, Inc. Pharmaceutical agent containing hyaluronan as an active ingredient
JP2009091248A (ja) * 2006-01-17 2009-04-30 Toshitsu Kagaku Kenkyusho:Kk 外傷性神経障害および／または運動機能障害の治療薬
BRPI0621470A2 (pt) 2006-12-05 2011-12-13 Glycoscience Lab Inc agente terapêutico para artrite degenerativa
US8529951B1 (en) 2007-02-21 2013-09-10 Anand Ramamurthi Elastogenic cues and methods for using same
FR2919185B1 (fr) * 2007-07-23 2010-09-10 Ard Sa Utilisation d'acide hyaluronique pour la preparation de compositions destinees a l'amelioration notamment de l'etat des muqueuses
US9493755B2 (en) 2012-02-21 2016-11-15 Bloomage Freda Biopharm Co., Ltd. Bacillus, hyaluronidase, and uses thereof
JP2019513799A (ja) * 2016-04-12 2019-05-30 イラストリス ファーマシューティカルズ、インク． 化合物の局所適用を目的とした組成物
JP2018168263A (ja) * 2017-03-29 2018-11-01 日油株式会社 植物性プロテオグリカン及びその用途
EP3694489A4 (de) * 2017-10-11 2021-06-30 Illustris Pharmaceuticals, Inc. Verfahren und zusammensetzung zur topischen verabreichung

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3482812D1 (de) * 1983-10-11 1990-08-30 Fidia Spa Fraktionen von hyaluronsaeure mit pharmazeutischer aktivitaet, verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen.
JP2604135B2 (ja) * 1986-02-28 1997-04-30 ライオン株式会社 口腔骨疾患治療剤
US5041138A (en) * 1986-11-20 1991-08-20 Massachusetts Institute Of Technology Neomorphogenesis of cartilage in vivo from cell culture
US5079236A (en) * 1987-05-27 1992-01-07 Hyal Pharmaceutical Corporation Pure, sterile, pyrogen-free hyaluronic acid formulations their methods of preparation and methods of use
GB2215209B (en) * 1988-03-14 1992-08-26 Osmed Inc Method and apparatus for biodegradable, osteogenic, bone graft substitute device
JPH01265970A (ja) * 1988-04-19 1989-10-24 Shiseido Co Ltd ヒアルロン酸を含有させたコラーゲン水溶液又は水分散液
US5059123A (en) * 1990-05-14 1991-10-22 Jernberg Gary R Periodontal barrier and method for aiding periodontal tissue regeneration
SE501217C2 (sv) * 1990-12-06 1994-12-12 Skandigen Ab Cellproliferationsmatris och användning därav

Also Published As

Publication number Publication date
AU677189B2 (en) 1997-04-17
ATE177641T1 (de) 1999-04-15
DE69324006T2 (de) 1999-11-11
EP0637245A1 (de) 1995-02-08
ITPD920071A0 (it) 1992-04-17
JPH08508973A (ja) 1996-09-24
CA2118219A1 (en) 1993-10-28
CA2118219C (en) 2004-06-01
IT1260148B (it) 1996-03-28
WO1993020827A1 (en) 1993-10-28
EP0637245B1 (de) 1999-03-17
KR100310277B1 (ko) 2001-12-28
US5646129A (en) 1997-07-08
ITPD920071A1 (it) 1993-10-17
AU4040493A (en) 1993-11-18
ES2130268T3 (es) 1999-07-01
JP3333205B2 (ja) 2002-10-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: FIDIA FARMACEUTICI S.P.A., ABANO TERME, PADUA/PADO