IT1306644B1 - Strutture tridimensionali comprendenti derivati dell'acido ialuronicoottenibili mediante la tecnica antisolvente supercritico. - Google Patents
Strutture tridimensionali comprendenti derivati dell'acido ialuronicoottenibili mediante la tecnica antisolvente supercritico.Info
- Publication number
- IT1306644B1 IT1306644B1 IT1999PD000071A ITPD990071A IT1306644B1 IT 1306644 B1 IT1306644 B1 IT 1306644B1 IT 1999PD000071 A IT1999PD000071 A IT 1999PD000071A IT PD990071 A ITPD990071 A IT PD990071A IT 1306644 B1 IT1306644 B1 IT 1306644B1
- Authority
- IT
- Italy
- Prior art keywords
- hyaluronic acid
- acid derivatives
- dimensional structures
- structures including
- including hyaluronic
- Prior art date
Links
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical class CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title abstract 2
- 238000001808 supercritical antisolvent technique Methods 0.000 title 1
- 239000012296 anti-solvent Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
- 238000001356 surgical procedure Methods 0.000 abstract 1
Classifications
-
- D—TEXTILES; PAPER
- D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
- D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
- D01F9/00—Artificial filaments or the like of other substances; Manufacture thereof; Apparatus specially adapted for the manufacture of carbon filaments
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
- C08J9/28—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof by elimination of a liquid phase from a macromolecular composition or article, e.g. drying of coagulum
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2201/00—Foams characterised by the foaming process
- C08J2201/04—Foams characterised by the foaming process characterised by the elimination of a liquid or solid component, e.g. precipitation, leaching out, evaporation
- C08J2201/054—Precipitating the polymer by adding a non-solvent or a different solvent
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2203/00—Foams characterized by the expanding agent
- C08J2203/08—Supercritical fluid
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/54—Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Materials Engineering (AREA)
- General Chemical & Material Sciences (AREA)
- Textile Engineering (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Materials For Medical Uses (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1999PD000071A IT1306644B1 (it) | 1999-04-08 | 1999-04-08 | Strutture tridimensionali comprendenti derivati dell'acido ialuronicoottenibili mediante la tecnica antisolvente supercritico. |
| ES00931057T ES2194727T3 (es) | 1999-04-08 | 2000-04-06 | Estructuras tridimensionales que contienen derivados del acido hialuronico obtenidos por la tecnica del antidisolvente supercritico. |
| AU49126/00A AU765563B2 (en) | 1999-04-08 | 2000-04-06 | Three-dimensional structures containing hyaluronic acid derivatives obtained by the supercritical antisolvent technique |
| EP00931057A EP1169387B1 (en) | 1999-04-08 | 2000-04-06 | Three-dimensional structures containing hyaluronic acid derivatives obtained by the supercritical antisolvent technique |
| DE60001640T DE60001640T2 (de) | 1999-04-08 | 2000-04-06 | Dreidimensionale struktur enthaltend hyaluronsäurederivat, hergestellt durch die technik von superkritischen antilösungsmitteln |
| CA002369284A CA2369284C (en) | 1999-04-08 | 2000-04-06 | Three-dimensional structures containing hyaluronic acid derivatives obtained by the supercritical antisolvent technique |
| AT00931057T ATE234341T1 (de) | 1999-04-08 | 2000-04-06 | Dreidimensionale struktur enthaltend hyaluronsäurederivat, hergestellt durch die technik von superkritischen antilösungsmitteln |
| US09/958,144 US7087745B1 (en) | 1999-04-08 | 2000-04-06 | Three-dimensional structures containing hyaluronic acid derivatives obtained by the supercritical antisolvent technique |
| PCT/EP2000/003081 WO2000061675A1 (en) | 1999-04-08 | 2000-04-06 | Three-dimensional structures containing hyaluronic acid derivatives obtained by the supercritical antisolvent technique |
| JP2000611610A JP2002541888A (ja) | 1999-04-08 | 2000-04-06 | 超臨界抗溶媒技術により得られるヒアルロン酸誘導体含有三次元構造体 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1999PD000071A IT1306644B1 (it) | 1999-04-08 | 1999-04-08 | Strutture tridimensionali comprendenti derivati dell'acido ialuronicoottenibili mediante la tecnica antisolvente supercritico. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ITPD990071A1 ITPD990071A1 (it) | 2000-10-08 |
| IT1306644B1 true IT1306644B1 (it) | 2001-10-02 |
Family
ID=11392548
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT1999PD000071A IT1306644B1 (it) | 1999-04-08 | 1999-04-08 | Strutture tridimensionali comprendenti derivati dell'acido ialuronicoottenibili mediante la tecnica antisolvente supercritico. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7087745B1 (it) |
| EP (1) | EP1169387B1 (it) |
| JP (1) | JP2002541888A (it) |
| AT (1) | ATE234341T1 (it) |
| AU (1) | AU765563B2 (it) |
| CA (1) | CA2369284C (it) |
| DE (1) | DE60001640T2 (it) |
| ES (1) | ES2194727T3 (it) |
| IT (1) | IT1306644B1 (it) |
| WO (1) | WO2000061675A1 (it) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITPD20010032A1 (it) | 2001-02-09 | 2002-08-09 | Fidia Advanced Biopolymers Srl | Innesti ingegnerizzati per la riparazione di difetti osteocondrali |
| RU2220729C2 (ru) * | 2002-01-31 | 2004-01-10 | Общество с ограниченной ответственностью "Научный Центр системных исследований и технологий 2000" | Гелевая композиция, используемая в стоматологии |
| FR2850282B1 (fr) | 2003-01-27 | 2007-04-06 | Jerome Asius | Implant injectable a base de ceramique pour le comblement de rides, depressions cutanees et cicatrices, et sa preparation |
| CA2520045A1 (en) * | 2003-04-04 | 2004-10-14 | Bayco Consulting Limited | Vascular stent having a hyaluronic acid polymer coating |
| US8512730B2 (en) * | 2004-07-12 | 2013-08-20 | Isto Technologies, Inc. | Methods of tissue repair and compositions therefor |
| CA2570521C (en) * | 2004-07-12 | 2013-06-25 | Isto Technologies, Inc. | Tissue matrix system |
| ES2528272T3 (es) * | 2005-12-07 | 2015-02-06 | Isto Technologies Inc. | Métodos de reparación de cartílago |
| ITPD20060219A1 (it) | 2006-05-31 | 2007-12-01 | Fidia Farmaceutici | Composizioni farmaceutiche contenenti acido ialuronico solfatato nel trattamento dell'osteoartrosi |
| JP5758797B2 (ja) | 2008-04-04 | 2015-08-05 | ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション | アルキル化半合成グリコサミノグリカンエーテルならびにその製造および使用方法 |
| WO2010028025A1 (en) | 2008-09-02 | 2010-03-11 | Gurtner Geoffrey C | Threads of hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof |
| US9522162B2 (en) | 2011-03-23 | 2016-12-20 | University Of Utah Research Foundation | Methods for treating or preventing urological inflammation |
| US10245306B2 (en) | 2012-11-16 | 2019-04-02 | Isto Technologies Ii, Llc | Flexible tissue matrix and methods for joint repair |
| CZ2013913A3 (cs) * | 2013-11-21 | 2015-06-03 | Contipro Biotech S.R.O. | Objemný nanovlákenný materiál na bázi kyseliny hyaluronové, jejích solí nebo jejich derivátů, způsob jeho přípravy, způsob jeho modifikace, modifikovaný nanovlákenný materiál, nanovlákenný útvar a jejich použití |
| US10179191B2 (en) | 2014-10-09 | 2019-01-15 | Isto Technologies Ii, Llc | Flexible tissue matrix and methods for joint repair |
| CN105734604B (zh) * | 2016-03-03 | 2017-08-25 | 武汉大学 | 一种立体复合多糖凝胶及其电化学3d打印制备方法和应用 |
| US11337994B2 (en) | 2016-09-15 | 2022-05-24 | University Of Utah Research Foundation | In situ gelling compositions for the treatment or prevention of inflammation and tissue damage |
| CN111228653A (zh) | 2018-11-13 | 2020-06-05 | 格莱科米拉治疗公司 | 用电离辐射加强癌症治疗的方法 |
| JP2019104938A (ja) * | 2019-04-04 | 2019-06-27 | イビデン株式会社 | ヒアルロン酸及び/又はその塩の粉末 |
| JP2019104937A (ja) * | 2019-04-04 | 2019-06-27 | イビデン株式会社 | ヒアルロン酸及び/又はその塩の粉末 |
| CN110423291B (zh) * | 2019-09-06 | 2020-06-16 | 焦点生物医药有限公司 | 一种速溶透明质酸钠制备方法 |
| WO2025072953A1 (en) * | 2023-09-28 | 2025-04-03 | University Of Massachusetts | Composition for depolymerizing resins and methods of accomplishing the same |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE7811306L (sv) | 1978-11-01 | 1980-05-02 | Rothman Gunnvor | Antikoagulationsmedel samt sett for dess framstellning |
| FR2553099B1 (fr) | 1983-10-11 | 1989-09-08 | Fidia Spa | Fractions d'acide hyaluronique ayant une activite pharmaceutique, procedes pour leur preparation et compositions pharmaceutiques les contenant |
| US4851521A (en) | 1985-07-08 | 1989-07-25 | Fidia, S.P.A. | Esters of hyaluronic acid |
| FR2584728B1 (fr) | 1985-07-12 | 1987-11-20 | Choay Sa | Procede de sulfatation de glycosaminoglycanes et de leurs fragments |
| IT1198449B (it) | 1986-10-13 | 1988-12-21 | F I D I Farmaceutici Italiani | Esteri di alcoli polivalenti di acido ialuronico |
| DK505588D0 (da) | 1988-02-26 | 1988-09-09 | Jesper Hamburger | Middel og anvendelse af samme |
| IT1219942B (it) | 1988-05-13 | 1990-05-24 | Fidia Farmaceutici | Esteri polisaccaridici |
| IT1219587B (it) | 1988-05-13 | 1990-05-18 | Fidia Farmaceutici | Polisaccaridi carbossiilici autoreticolati |
| IT1247175B (it) | 1991-04-19 | 1994-12-12 | Fidia Spa | Procedimento per la purificazione di acido ialuronico e frazione di acido ialuronico puro per uso oftalmico. |
| IT1254704B (it) * | 1991-12-18 | 1995-10-09 | Mini Ricerca Scient Tecnolog | Tessuto non tessuto essenzialmente costituito da derivati dell'acido ialuronico |
| IT1260148B (it) | 1992-04-17 | 1996-03-28 | Fidia Spa | Impiego di preparazioni di acido ialuronico per la formazione di tessuto osseo |
| ITPD940054A1 (it) | 1994-03-23 | 1995-09-23 | Fidia Advanced Biopolymers Srl | Polisaccaridi solfatati |
| WO1996029998A1 (en) * | 1995-03-28 | 1996-10-03 | Fidia Advanced Biopolymers S.R.L. | Nanospheres comprising a biocompatible polysaccharide |
| US5833891A (en) * | 1996-10-09 | 1998-11-10 | The University Of Kansas | Methods for a particle precipitation and coating using near-critical and supercritical antisolvents |
| IT1287698B1 (it) | 1996-08-29 | 1998-08-18 | Fidia Advanced Biopolymers Srl | Fili da sutura essenzialmente costituiti da derivati esterei dello acido ialuronico |
| DK0971961T3 (da) | 1997-04-04 | 2003-03-24 | Fidia Advanced Biopolymers Srl | N-sulfaterede hyaluronsyreforbindelser, derivater deraf og en fremgangsmåde til deres fremstilling |
-
1999
- 1999-04-08 IT IT1999PD000071A patent/IT1306644B1/it active
-
2000
- 2000-04-06 JP JP2000611610A patent/JP2002541888A/ja active Pending
- 2000-04-06 ES ES00931057T patent/ES2194727T3/es not_active Expired - Lifetime
- 2000-04-06 AU AU49126/00A patent/AU765563B2/en not_active Ceased
- 2000-04-06 CA CA002369284A patent/CA2369284C/en not_active Expired - Fee Related
- 2000-04-06 EP EP00931057A patent/EP1169387B1/en not_active Expired - Lifetime
- 2000-04-06 WO PCT/EP2000/003081 patent/WO2000061675A1/en not_active Ceased
- 2000-04-06 DE DE60001640T patent/DE60001640T2/de not_active Expired - Lifetime
- 2000-04-06 AT AT00931057T patent/ATE234341T1/de active
- 2000-04-06 US US09/958,144 patent/US7087745B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002541888A (ja) | 2002-12-10 |
| EP1169387A1 (en) | 2002-01-09 |
| ATE234341T1 (de) | 2003-03-15 |
| ES2194727T3 (es) | 2003-12-01 |
| DE60001640D1 (de) | 2003-04-17 |
| CA2369284A1 (en) | 2000-10-19 |
| WO2000061675A1 (en) | 2000-10-19 |
| ITPD990071A1 (it) | 2000-10-08 |
| CA2369284C (en) | 2010-01-12 |
| US7087745B1 (en) | 2006-08-08 |
| AU765563B2 (en) | 2003-09-25 |
| AU4912600A (en) | 2000-11-14 |
| DE60001640T2 (de) | 2004-03-25 |
| EP1169387B1 (en) | 2003-03-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IT1306644B1 (it) | Strutture tridimensionali comprendenti derivati dell'acido ialuronicoottenibili mediante la tecnica antisolvente supercritico. | |
| ITPD20020064A1 (it) | Derivati esterei dell'acido ialuronico per la preparazione di idrogelda utilizzare in campo biomedico, sanitario e chirurgico e come sistem | |
| PT1144459E (pt) | Acidos hialuronicos reticulados e as suas utilizacoes em medicina | |
| ES2272465T3 (es) | Complejos de clatrato constituidos por derivados del acido hialuronico y su utilizacion como productos farmaceuticos. | |
| NO912769D0 (no) | Avleveringssystem for medikamenter. | |
| BR0007985A (pt) | Processo para a preparação de derivados multiplamente reticulados do ácido hialurÈnico (ha), ha multiplamente reticulado, ha reticulado em um ou mais polìmeros diferentes de ha, ha reticulado em um segundo polìmero, produto, e, uso de um derivado de ha multiplamente reticulado | |
| DE69721489D1 (de) | Herstellungsverfahren von löslichen verabreichungssystemen unter verwendung von flüchtigen salzen | |
| ES2089844T3 (es) | Sistema de administracion de medicamentos a base de dicetopiperazina. | |
| DE69533370D1 (de) | Heparinähnliche sulfatierte Polysaccharide | |
| ITPD20000207A0 (it) | Nuovi derivati cross-linkati dell'acido ialuronico. | |
| DK0981381T3 (da) | Polyhydroxyalkanoater ti anvendelser in vivo | |
| IT1306679B1 (it) | Uso dei derivati dell'acido ialuronico per la preparazione dicomposizoni farmaceutiche e biomateriali per la prevenzione della | |
| DE68928993D1 (de) | Arzneimittelzubereitung | |
| CY1105609T1 (el) | Μια διαδικασια για παραγωγη σωματιδιων με μετατροπη μιας αμορφης και/ή μετα-σταθερης κρυσταλλικη περιοχης σε κρυσταλλικη κατασταση | |
| TR200101163T2 (tr) | Safra suyu ikameli fenil-alkenoilguanidinler, üretim yöntemleri, kullanımları | |
| IT1306643B1 (it) | Processo per la preparazione dei composti autoreticolati dell'acidoialuronico e dei suoi derivati ottenibili mediante la tecnica | |
| SE9603480L (sv) | Beredningsform för svårlösliga läkemedel | |
| EA200200914A1 (ru) | Система контроля дозирования для однократного ежедневного приема назначенного ципрофлоксацина | |
| HRP20020167B1 (en) | Spherical telithromycin clusters, method for the production and use thereof in the preparation of pharmaceutical forms | |
| DE50000864D1 (de) | Verwendung von desoxypeganin zur behandlung von drogenabhängigkeit | |
| DE60032372D1 (de) | Arzneizubereitungen enthaltend paclitaxel eingeschlossen in nanopartikeln von polymerischen mizellen | |
| DK1231908T3 (da) | Farmaceutisk præparat, der omfatter en NO-donorforbindelse samt anvendelse heraf | |
| PT1228031E (pt) | Derivados do acido 15-hidroxieicosatetraenoico modificados na cadeia omega e sua utilizacao no tratamento da secura ocular | |
| ATE254469T1 (de) | Verfahren zur verminderung der renalen aufnahme von antikörperfragmenten | |
| SE9000207D0 (sv) | Laekemedel samt anvaendningen av detsamma |