KR100310277B1 - 뼈 형성 촉진용 저분자량 하이알루론산의 제조 - Google Patents

뼈 형성 촉진용 저분자량 하이알루론산의 제조 Download PDF

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Publication number
KR100310277B1
KR100310277B1 KR1019940703659A KR19940703659A KR100310277B1 KR 100310277 B1 KR100310277 B1 KR 100310277B1 KR 1019940703659 A KR1019940703659 A KR 1019940703659A KR 19940703659 A KR19940703659 A KR 19940703659A KR 100310277 B1 KR100310277 B1 KR 100310277B1
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KR
South Korea
Prior art keywords
hyaluronic acid
pct
preparation
molecular weight
low molecular
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Application number
KR1019940703659A
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English (en)
Inventor
란프란코칼레가로
아우렐리오로메오
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Publication of KR100310277B1 publication Critical patent/KR100310277B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Materials For Medical Uses (AREA)
KR1019940703659A 1992-04-17 1994-10-14 뼈 형성 촉진용 저분자량 하이알루론산의 제조 KR100310277B1 (ko)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITPD920071A IT1260148B (it) 1992-04-17 1992-04-17 Impiego di preparazioni di acido ialuronico per la formazione di tessuto osseo

Publications (1)

Publication Number Publication Date
KR100310277B1 true KR100310277B1 (ko) 2001-12-28

Family

ID=11389901

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940703659A KR100310277B1 (ko) 1992-04-17 1994-10-14 뼈 형성 촉진용 저분자량 하이알루론산의 제조

Country Status (11)

Country Link
US (1) US5646129A (ko)
EP (1) EP0637245B1 (ko)
JP (1) JP3333205B2 (ko)
KR (1) KR100310277B1 (ko)
AT (1) ATE177641T1 (ko)
AU (1) AU677189B2 (ko)
CA (1) CA2118219C (ko)
DE (1) DE69324006T2 (ko)
ES (1) ES2130268T3 (ko)
IT (1) IT1260148B (ko)
WO (1) WO1993020827A1 (ko)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995001181A1 (en) * 1993-07-01 1995-01-12 Allelix Biopharmaceuticals Inc. Hyaluronic acid fragments and their therapeutic use
IT1282219B1 (it) * 1995-12-20 1998-03-16 Fidia Advanced Biopolymers Srl Processo chimico fisico combinato per la preparazione di frazioni di acido ialuronico a basso peso molecolare caratterizzate da bassa
US6875753B1 (en) 1996-03-14 2005-04-05 The Governors Of The University Of Alberta Methods for cell mobilization using in vivo treatment with hyaluronan (HA)
US20050101564A1 (en) * 1996-04-02 2005-05-12 Pilarski Linda M. Methods for cell mobilization using in vivo treatment with hyaluronan (HA)
US5939047A (en) * 1996-04-16 1999-08-17 Jernberg; Gary R. Local delivery of chemotherapeutic agents for treatment of periodontal disease
US6872819B1 (en) 1998-05-27 2005-03-29 Fidia Advanced Biopolymers S.R.L. Biomaterials containing hyaluronic acid derivatives in the form of three-dimensional structures free from cellular components or products thereof for the in vivo regeneration of tissue cells
JP3032824B1 (ja) * 1999-01-28 2000-04-17 東京医科歯科大学長 骨誘導促進剤
ES2242600T3 (es) * 1999-02-04 2005-11-16 Sdgi Holdings, Inc. Composiciones de pasta osteogenica y sus usos.
IT1306644B1 (it) 1999-04-08 2001-10-02 Fidia Advanced Biopolymers Srl Strutture tridimensionali comprendenti derivati dell'acido ialuronicoottenibili mediante la tecnica antisolvente supercritico.
US6726898B2 (en) 2000-11-17 2004-04-27 Gary R. Jernberg Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease
US6576226B1 (en) 2000-11-17 2003-06-10 Gary R. Jernberg Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease
JP2004250592A (ja) * 2003-02-20 2004-09-09 Seikagaku Kogyo Co Ltd 紫外線照射による低分子化グリコサミノグリカンの製造方法
US20040180025A1 (en) * 2003-03-12 2004-09-16 New Life Resources, Llc Therapeutic, nutraceutical and cosmetic applications for eggshell membrane and processed eggshell membrane preparations
US20080063677A1 (en) * 2004-03-10 2008-03-13 New Life Resources, Llc Therapeutic, nutraceutical and cosmetic applications for eggshell membrane and processed eggshell membrane preparations
US6946551B2 (en) * 2003-03-12 2005-09-20 New Life Resources, Llc Preparation of hyaluronic acid from eggshell membrane
US8580315B2 (en) * 2004-03-10 2013-11-12 Esm Technologies, Llc Anti-inflammatory activity of eggshell membrane and processed eggshell membrane preparations
US20050226936A1 (en) 2004-04-08 2005-10-13 Q-Med Ab Method of soft tissue augmentation
US20060183709A1 (en) * 2005-02-15 2006-08-17 Ahmad Alkayali Preparation of low molecular weight hyaluronic acid as a food supplement
US20100075921A1 (en) * 2005-02-15 2010-03-25 Ahmad Alkayali Prêparation of hyaluronic acid with desired low molecular weight as a food supplement
US20070099867A1 (en) * 2005-05-24 2007-05-03 Glycoscience Laboratories, Inc. Pharmaceutical agent containing hyaluronan as an active ingredient
JP2009091248A (ja) * 2006-01-17 2009-04-30 Toshitsu Kagaku Kenkyusho:Kk 外傷性神経障害および／または運動機能障害の治療薬
BRPI0621470A2 (pt) 2006-12-05 2011-12-13 Glycoscience Lab Inc agente terapêutico para artrite degenerativa
US8529951B1 (en) 2007-02-21 2013-09-10 Anand Ramamurthi Elastogenic cues and methods for using same
FR2919185B1 (fr) * 2007-07-23 2010-09-10 Ard Sa Utilisation d'acide hyaluronique pour la preparation de compositions destinees a l'amelioration notamment de l'etat des muqueuses
WO2013123791A1 (zh) 2012-02-21 2013-08-29 华熙福瑞达生物医药有限公司 一种芽孢杆菌、一种透明质酸酶、以及其用途
MX2018012486A (es) * 2016-04-12 2019-06-06 Illustris Pharmaceuticals Inc Composiciones para aplicacion topica de compuestos.
JP2018168263A (ja) * 2017-03-29 2018-11-01 日油株式会社 植物性プロテオグリカン及びその用途
CA3078631A1 (en) * 2017-10-11 2019-04-18 Jacob M. Waugh Methods and compositions for topical delivery
US20210000910A1 (en) 2019-07-03 2021-01-07 Jysk Skin Solutions Pte Ltd Topical compositions
US12083204B2 (en) 2022-06-02 2024-09-10 L'oreal Topical composition for homeostatic delivery of nitric oxide and uses thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0138572A2 (en) * 1983-10-11 1985-04-24 FIDIA S.p.A. Hyaluronic acid fractions having pharmaceutical activity, methods for preparation thereof, and pharmaceutical compositions containing the same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2604135B2 (ja) * 1986-02-28 1997-04-30 ライオン株式会社 口腔骨疾患治療剤
US5041138A (en) * 1986-11-20 1991-08-20 Massachusetts Institute Of Technology Neomorphogenesis of cartilage in vivo from cell culture
US5079236A (en) * 1987-05-27 1992-01-07 Hyal Pharmaceutical Corporation Pure, sterile, pyrogen-free hyaluronic acid formulations their methods of preparation and methods of use
GB2215209B (en) * 1988-03-14 1992-08-26 Osmed Inc Method and apparatus for biodegradable, osteogenic, bone graft substitute device
JPH01265970A (ja) * 1988-04-19 1989-10-24 Shiseido Co Ltd ヒアルロン酸を含有させたコラーゲン水溶液又は水分散液
US5059123A (en) * 1990-05-14 1991-10-22 Jernberg Gary R Periodontal barrier and method for aiding periodontal tissue regeneration
SE501217C2 (sv) * 1990-12-06 1994-12-12 Skandigen Ab Cellproliferationsmatris och användning därav

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0138572A2 (en) * 1983-10-11 1985-04-24 FIDIA S.p.A. Hyaluronic acid fractions having pharmaceutical activity, methods for preparation thereof, and pharmaceutical compositions containing the same

Also Published As

Publication number Publication date
ITPD920071A0 (it) 1992-04-17
EP0637245B1 (en) 1999-03-17
CA2118219C (en) 2004-06-01
ITPD920071A1 (it) 1993-10-17
DE69324006D1 (de) 1999-04-22
ES2130268T3 (es) 1999-07-01
DE69324006T2 (de) 1999-11-11
AU4040493A (en) 1993-11-18
ATE177641T1 (de) 1999-04-15
JP3333205B2 (ja) 2002-10-15
JPH08508973A (ja) 1996-09-24
AU677189B2 (en) 1997-04-17
EP0637245A1 (en) 1995-02-08
CA2118219A1 (en) 1993-10-28
WO1993020827A1 (en) 1993-10-28
IT1260148B (it) 1996-03-28
US5646129A (en) 1997-07-08

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