DE69232698T2 - Neuer megakaryocyten-verstärker - Google Patents

Neuer megakaryocyten-verstärker

Info

Publication number
DE69232698T2
DE69232698T2 DE69232698T DE69232698T DE69232698T2 DE 69232698 T2 DE69232698 T2 DE 69232698T2 DE 69232698 T DE69232698 T DE 69232698T DE 69232698 T DE69232698 T DE 69232698T DE 69232698 T2 DE69232698 T2 DE 69232698T2
Authority
DE
Germany
Prior art keywords
megakaryocyte
enhancer
meg
megakaryocyte enhancer
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69232698T
Other languages
German (de)
English (en)
Other versions
DE69232698D1 (de
Inventor
Kunihiro Hattori
Masayoshi Oh-Eda
Nozomi Yamaguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of DE69232698D1 publication Critical patent/DE69232698D1/de
Application granted granted Critical
Publication of DE69232698T2 publication Critical patent/DE69232698T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Amplifiers (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69232698T 1991-12-27 1992-12-24 Neuer megakaryocyten-verstärker Expired - Lifetime DE69232698T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP36152291 1991-12-27
JP12251892 1992-03-31
PCT/JP1992/001689 WO1993013132A1 (fr) 1991-12-27 1992-12-24 Nouvel amplificateur de megakaryocytes

Publications (2)

Publication Number Publication Date
DE69232698D1 DE69232698D1 (de) 2002-08-29
DE69232698T2 true DE69232698T2 (de) 2003-03-20

Family

ID=26459624

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69232698T Expired - Lifetime DE69232698T2 (de) 1991-12-27 1992-12-24 Neuer megakaryocyten-verstärker

Country Status (12)

Country Link
US (1) US5498698A (enExample)
EP (1) EP0621285B1 (enExample)
JP (1) JP3328341B2 (enExample)
KR (1) KR100233701B1 (enExample)
CN (1) CN1075148A (enExample)
AT (1) ATE221084T1 (enExample)
AU (1) AU658040B2 (enExample)
CA (1) CA2126680C (enExample)
DE (1) DE69232698T2 (enExample)
ES (1) ES2180542T3 (enExample)
TW (1) TW224975B (enExample)
WO (1) WO1993013132A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL107366A (en) * 1992-10-23 2003-03-12 Chugai Pharmaceutical Co Ltd Genes coding for megakaryocyte potentiator
US5795569A (en) * 1994-03-31 1998-08-18 Amgen Inc. Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation
EP0690127B1 (en) * 1994-03-31 1998-08-05 Amgen Inc. Compositions and methods for stimulating megakaryocyte growth and differentiation
ES2212071T3 (es) * 1996-01-05 2004-07-16 The Government Of The United States Of America, As Represented By The Secretary, Department Of Antigeno de mesotelio y kits para marcarlo como diana.
US7375183B1 (en) 1996-01-05 2008-05-20 The United States Of America As Represented By The Department Of Health And Human Services Mesothelin, immunogenic peptides derived therefrom, and compositions comprising mesothelin, or immunogenic peptides thereof
US6809184B1 (en) * 1997-12-01 2004-10-26 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Antibodies, including FV molecules, and immunoconjugates having high binding affinity for mesothelin and methods for their use
AU3877800A (en) 1999-03-30 2000-10-16 Trustees Of Boston University Compositions and methods for producing platelets and/or proplatelets from megakaryocytes
US7081518B1 (en) 1999-05-27 2006-07-25 The United States Of America As Represented By The Department Of Health And Human Services Anti-mesothelin antibodies having high binding affinity
US9200036B2 (en) 2002-07-12 2015-12-01 The Johns Hopkins University Mesothelin vaccines and model systems
US20050175625A1 (en) * 2002-07-12 2005-08-11 The Johns Hopkins University Mesothelin vaccines and model systems
US20090110702A1 (en) 2002-07-12 2009-04-30 The Johns Hopkins University Mesothelin Vaccines and Model Systems and Control of Tumors
US20040180387A1 (en) * 2003-03-13 2004-09-16 Fujirebio Diagnostics, Inc. Detection of urinary mesothelin-/megakaryocyte potentiating factor-related peptides for assessment of ovarian cancer
CN101951946B (zh) 2007-10-01 2014-12-10 百时美施贵宝公司 结合间皮素的人抗体及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR920703641A (ko) * 1990-12-28 1992-12-18 유미꾸라 레이이찌 신규한 거핵구 증폭인자 및 그의 제조방법
JPH04295500A (ja) * 1991-03-26 1992-10-20 Asahi Chem Ind Co Ltd 新規な巨核球増幅因子とその製法

Also Published As

Publication number Publication date
JP3328341B2 (ja) 2002-09-24
DE69232698D1 (de) 2002-08-29
ES2180542T3 (es) 2003-02-16
AU3172193A (en) 1993-07-28
US5498698A (en) 1996-03-12
EP0621285A4 (en) 1995-05-24
KR100233701B1 (ko) 1999-12-01
TW224975B (enExample) 1994-06-11
AU658040B2 (en) 1995-03-30
EP0621285B1 (en) 2002-07-24
JPH05331200A (ja) 1993-12-14
CA2126680C (en) 2002-10-08
EP0621285A1 (en) 1994-10-26
ATE221084T1 (de) 2002-08-15
WO1993013132A1 (fr) 1993-07-08
CN1075148A (zh) 1993-08-11
KR940703858A (ko) 1994-12-12
CA2126680A1 (en) 1993-07-08

Similar Documents

Publication Publication Date Title
DE69119869T2 (de) Chimeres Fibroblasten-Wachstumsfaktor
DE69027961T2 (de) Protein, DNA und ihre Verwendung
DE69232698T2 (de) Neuer megakaryocyten-verstärker
DE68914582T2 (de) Endothelin-DNA und ihre Verwendung.
DE69132708T2 (de) Therapeutische Vervendung von Peptiden mit Thrombospondin - ähnlicher Aktivität
CH658459A5 (de) Gereinigtes gemisch von human-leukozyten-interferonen.
JPS6133120A (ja) 腫瘍増殖阻害因子およびその調製方法
TW211585B (enExample)
EP0497915B1 (de) hPTH-FRAGMENT-(1-37), SEINE HERSTELLUNG, DIESES ENTHALTENDE ARZNEIMITTEL UND SEINE VERWENDUNG
DE69012377T2 (de) Polypeptid und dessen Herstellung.
DE69232716T2 (de) Peptide mit thrombospondin-ähnlicher Aktivität und ihre therapeutische Verwendung
DE69424657T2 (de) Osteogene wachstums-oligopeptide und diese enthaltende pharmazeutische zusammensetzungen
DE69230879T2 (de) Verwendung von Hepatocyten-Wachstumsfaktoren zur Herstellung eines Vermehrungssystems für Hematopoietische Stammzellen
AU689560B2 (en) Method for stimulating profileration of colon cells using POMC-76-103
DE69309827T2 (de) Modifizierter Plättchenfaktor-4
AT400444B (de) Verfahren zur herstellung von oncostatin m
EP2332964B1 (de) Apoptotisch wirksame Peptide
EP0517789B1 (de) Inhibitor der proliferation von endothelzellen
KR20250118834A (ko) 삼중 나선 구조를 갖는 재조합 xvii형 콜라겐 및 이의 용도
DE69936192T2 (de) Menschliches stanniocalcin und seine verwendung zur hemmung der adipogenese
CN108949730A (zh) 一种重组变构胶原酶的制备方法及其应用
DE69018357T2 (de) Mutein von HST-1 und seine Herstellung.
DE3421731A1 (de) Humaner-tumor-nekrose-faktor
DE69032471T2 (de) Proteine mit onkostatin-m-aktivität und verfahren zu ihrer herstellung
DE69228559T2 (de) Dna-fragment kodierend für einen tumorzell-proliferationsinhibitierenden faktor

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
R071 Expiry of right

Ref document number: 621285

Country of ref document: EP