CN1075148A - 新的巨核细胞扩增基因 - Google Patents

新的巨核细胞扩增基因 Download PDF

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Publication number
CN1075148A
CN1075148A CN92113842A CN92113842A CN1075148A CN 1075148 A CN1075148 A CN 1075148A CN 92113842 A CN92113842 A CN 92113842A CN 92113842 A CN92113842 A CN 92113842A CN 1075148 A CN1075148 A CN 1075148A
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CN
China
Prior art keywords
megalokaryocyte
meg
pot
sequence
amplification gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN92113842A
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English (en)
Chinese (zh)
Inventor
山口希
大枝匡义
服部有宏
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of CN1075148A publication Critical patent/CN1075148A/zh
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • C07K14/4705Regulators; Modulating activity stimulating, promoting or activating activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Amplifiers (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN92113842A 1991-12-27 1992-12-27 新的巨核细胞扩增基因 Pending CN1075148A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP36152291 1991-12-27
JP361522/91 1991-12-27
JP122518/92 1992-03-31
JP12251892 1992-03-31

Publications (1)

Publication Number Publication Date
CN1075148A true CN1075148A (zh) 1993-08-11

Family

ID=26459624

Family Applications (1)

Application Number Title Priority Date Filing Date
CN92113842A Pending CN1075148A (zh) 1991-12-27 1992-12-27 新的巨核细胞扩增基因

Country Status (12)

Country Link
US (1) US5498698A (enExample)
EP (1) EP0621285B1 (enExample)
JP (1) JP3328341B2 (enExample)
KR (1) KR100233701B1 (enExample)
CN (1) CN1075148A (enExample)
AT (1) ATE221084T1 (enExample)
AU (1) AU658040B2 (enExample)
CA (1) CA2126680C (enExample)
DE (1) DE69232698T2 (enExample)
ES (1) ES2180542T3 (enExample)
TW (1) TW224975B (enExample)
WO (1) WO1993013132A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL107366A (en) * 1992-10-23 2003-03-12 Chugai Pharmaceutical Co Ltd Genes coding for megakaryocyte potentiator
US5795569A (en) * 1994-03-31 1998-08-18 Amgen Inc. Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation
EP0690127B1 (en) * 1994-03-31 1998-08-05 Amgen Inc. Compositions and methods for stimulating megakaryocyte growth and differentiation
ES2212071T3 (es) * 1996-01-05 2004-07-16 The Government Of The United States Of America, As Represented By The Secretary, Department Of Antigeno de mesotelio y kits para marcarlo como diana.
US7375183B1 (en) 1996-01-05 2008-05-20 The United States Of America As Represented By The Department Of Health And Human Services Mesothelin, immunogenic peptides derived therefrom, and compositions comprising mesothelin, or immunogenic peptides thereof
US6809184B1 (en) * 1997-12-01 2004-10-26 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Antibodies, including FV molecules, and immunoconjugates having high binding affinity for mesothelin and methods for their use
AU3877800A (en) 1999-03-30 2000-10-16 Trustees Of Boston University Compositions and methods for producing platelets and/or proplatelets from megakaryocytes
US7081518B1 (en) 1999-05-27 2006-07-25 The United States Of America As Represented By The Department Of Health And Human Services Anti-mesothelin antibodies having high binding affinity
US9200036B2 (en) 2002-07-12 2015-12-01 The Johns Hopkins University Mesothelin vaccines and model systems
US20050175625A1 (en) * 2002-07-12 2005-08-11 The Johns Hopkins University Mesothelin vaccines and model systems
US20090110702A1 (en) 2002-07-12 2009-04-30 The Johns Hopkins University Mesothelin Vaccines and Model Systems and Control of Tumors
US20040180387A1 (en) * 2003-03-13 2004-09-16 Fujirebio Diagnostics, Inc. Detection of urinary mesothelin-/megakaryocyte potentiating factor-related peptides for assessment of ovarian cancer
CN101951946B (zh) 2007-10-01 2014-12-10 百时美施贵宝公司 结合间皮素的人抗体及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR920703641A (ko) * 1990-12-28 1992-12-18 유미꾸라 레이이찌 신규한 거핵구 증폭인자 및 그의 제조방법
JPH04295500A (ja) * 1991-03-26 1992-10-20 Asahi Chem Ind Co Ltd 新規な巨核球増幅因子とその製法

Also Published As

Publication number Publication date
JP3328341B2 (ja) 2002-09-24
DE69232698D1 (de) 2002-08-29
ES2180542T3 (es) 2003-02-16
AU3172193A (en) 1993-07-28
US5498698A (en) 1996-03-12
EP0621285A4 (en) 1995-05-24
KR100233701B1 (ko) 1999-12-01
TW224975B (enExample) 1994-06-11
AU658040B2 (en) 1995-03-30
EP0621285B1 (en) 2002-07-24
JPH05331200A (ja) 1993-12-14
CA2126680C (en) 2002-10-08
EP0621285A1 (en) 1994-10-26
ATE221084T1 (de) 2002-08-15
WO1993013132A1 (fr) 1993-07-08
KR940703858A (ko) 1994-12-12
CA2126680A1 (en) 1993-07-08
DE69232698T2 (de) 2003-03-20

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