JP3328341B2 - 新規な巨核球増幅因子 - Google Patents

新規な巨核球増幅因子

Info

Publication number
JP3328341B2
JP3328341B2 JP34215192A JP34215192A JP3328341B2 JP 3328341 B2 JP3328341 B2 JP 3328341B2 JP 34215192 A JP34215192 A JP 34215192A JP 34215192 A JP34215192 A JP 34215192A JP 3328341 B2 JP3328341 B2 JP 3328341B2
Authority
JP
Japan
Prior art keywords
megakaryocyte
meg
amplification factor
pot
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP34215192A
Other languages
English (en)
Japanese (ja)
Other versions
JPH05331200A (ja
Inventor
希 山口
匡義 大枝
有宏 服部
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Priority to JP34215192A priority Critical patent/JP3328341B2/ja
Publication of JPH05331200A publication Critical patent/JPH05331200A/ja
Application granted granted Critical
Publication of JP3328341B2 publication Critical patent/JP3328341B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Amplifiers (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP34215192A 1991-12-27 1992-12-22 新規な巨核球増幅因子 Expired - Fee Related JP3328341B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP34215192A JP3328341B2 (ja) 1991-12-27 1992-12-22 新規な巨核球増幅因子

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP36152291 1991-12-27
JP4-122518 1992-03-31
JP3-361522 1992-03-31
JP12251892 1992-03-31
JP34215192A JP3328341B2 (ja) 1991-12-27 1992-12-22 新規な巨核球増幅因子

Publications (2)

Publication Number Publication Date
JPH05331200A JPH05331200A (ja) 1993-12-14
JP3328341B2 true JP3328341B2 (ja) 2002-09-24

Family

ID=26459624

Family Applications (1)

Application Number Title Priority Date Filing Date
JP34215192A Expired - Fee Related JP3328341B2 (ja) 1991-12-27 1992-12-22 新規な巨核球増幅因子

Country Status (12)

Country Link
US (1) US5498698A (enExample)
EP (1) EP0621285B1 (enExample)
JP (1) JP3328341B2 (enExample)
KR (1) KR100233701B1 (enExample)
CN (1) CN1075148A (enExample)
AT (1) ATE221084T1 (enExample)
AU (1) AU658040B2 (enExample)
CA (1) CA2126680C (enExample)
DE (1) DE69232698T2 (enExample)
ES (1) ES2180542T3 (enExample)
TW (1) TW224975B (enExample)
WO (1) WO1993013132A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL107366A (en) * 1992-10-23 2003-03-12 Chugai Pharmaceutical Co Ltd Genes coding for megakaryocyte potentiator
US5795569A (en) * 1994-03-31 1998-08-18 Amgen Inc. Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation
EP0690127B1 (en) * 1994-03-31 1998-08-05 Amgen Inc. Compositions and methods for stimulating megakaryocyte growth and differentiation
ES2212071T3 (es) * 1996-01-05 2004-07-16 The Government Of The United States Of America, As Represented By The Secretary, Department Of Antigeno de mesotelio y kits para marcarlo como diana.
US7375183B1 (en) 1996-01-05 2008-05-20 The United States Of America As Represented By The Department Of Health And Human Services Mesothelin, immunogenic peptides derived therefrom, and compositions comprising mesothelin, or immunogenic peptides thereof
US6809184B1 (en) * 1997-12-01 2004-10-26 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Antibodies, including FV molecules, and immunoconjugates having high binding affinity for mesothelin and methods for their use
AU3877800A (en) 1999-03-30 2000-10-16 Trustees Of Boston University Compositions and methods for producing platelets and/or proplatelets from megakaryocytes
US7081518B1 (en) 1999-05-27 2006-07-25 The United States Of America As Represented By The Department Of Health And Human Services Anti-mesothelin antibodies having high binding affinity
US9200036B2 (en) 2002-07-12 2015-12-01 The Johns Hopkins University Mesothelin vaccines and model systems
US20050175625A1 (en) * 2002-07-12 2005-08-11 The Johns Hopkins University Mesothelin vaccines and model systems
US20090110702A1 (en) 2002-07-12 2009-04-30 The Johns Hopkins University Mesothelin Vaccines and Model Systems and Control of Tumors
US20040180387A1 (en) * 2003-03-13 2004-09-16 Fujirebio Diagnostics, Inc. Detection of urinary mesothelin-/megakaryocyte potentiating factor-related peptides for assessment of ovarian cancer
CN101951946B (zh) 2007-10-01 2014-12-10 百时美施贵宝公司 结合间皮素的人抗体及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR920703641A (ko) * 1990-12-28 1992-12-18 유미꾸라 레이이찌 신규한 거핵구 증폭인자 및 그의 제조방법
JPH04295500A (ja) * 1991-03-26 1992-10-20 Asahi Chem Ind Co Ltd 新規な巨核球増幅因子とその製法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Ｊ．Ｂｉｏｌ．Ｃｈｅｍ．，１９８７年 ３月 ５日，２６２（７），３２６２−３２６８
Ｊ．Ｂｉｏｌ．Ｃｈｅｍ．，１９９４年 １月１４日，２６９（２），８０５−８０８
Ｊ．Ｂｉｏｌ．Ｃｈｅｍ．，１９９５年 ９月１５日，２７０（３７），２１９８４−２１９９０

Also Published As

Publication number Publication date
DE69232698D1 (de) 2002-08-29
ES2180542T3 (es) 2003-02-16
AU3172193A (en) 1993-07-28
US5498698A (en) 1996-03-12
EP0621285A4 (en) 1995-05-24
KR100233701B1 (ko) 1999-12-01
TW224975B (enExample) 1994-06-11
AU658040B2 (en) 1995-03-30
EP0621285B1 (en) 2002-07-24
JPH05331200A (ja) 1993-12-14
CA2126680C (en) 2002-10-08
EP0621285A1 (en) 1994-10-26
ATE221084T1 (de) 2002-08-15
WO1993013132A1 (fr) 1993-07-08
CN1075148A (zh) 1993-08-11
KR940703858A (ko) 1994-12-12
CA2126680A1 (en) 1993-07-08
DE69232698T2 (de) 2003-03-20

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