DE69231232T2 - Verfahren zur Immunoneutralisierung von nichtkastrierten männlichen Haustieren gegen LMRH und Peptide dafür - Google Patents
Verfahren zur Immunoneutralisierung von nichtkastrierten männlichen Haustieren gegen LMRH und Peptide dafürInfo
- Publication number
- DE69231232T2 DE69231232T2 DE69231232T DE69231232T DE69231232T2 DE 69231232 T2 DE69231232 T2 DE 69231232T2 DE 69231232 T DE69231232 T DE 69231232T DE 69231232 T DE69231232 T DE 69231232T DE 69231232 T2 DE69231232 T2 DE 69231232T2
- Authority
- DE
- Germany
- Prior art keywords
- lmrh
- immunoneutralizing
- peptides
- therefor
- castrated male
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0006—Contraceptive vaccins; Vaccines against sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9102513A FR2673377B1 (fr) | 1991-03-01 | 1991-03-01 | Procede pour ameliorer les qualites organoleptiques des animaux domestiques non castres. |
FR9115289A FR2685333B1 (fr) | 1991-12-10 | 1991-12-10 | Nouveau peptide notamment pour la realisation de conjugues immunogenes anti-lhrh, vaccins les incorporant et ensemble de vaccination y relatif. |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69231232D1 DE69231232D1 (de) | 2000-08-17 |
DE69231232T2 true DE69231232T2 (de) | 2001-01-04 |
Family
ID=26228546
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69231232T Expired - Lifetime DE69231232T2 (de) | 1991-03-01 | 1992-02-26 | Verfahren zur Immunoneutralisierung von nichtkastrierten männlichen Haustieren gegen LMRH und Peptide dafür |
Country Status (19)
Country | Link |
---|---|
US (1) | US5573767A (de) |
EP (1) | EP0501882B1 (de) |
JP (1) | JP3177246B2 (de) |
KR (1) | KR100257214B1 (de) |
AT (1) | ATE194625T1 (de) |
CA (1) | CA2081660C (de) |
CZ (1) | CZ287775B6 (de) |
DE (1) | DE69231232T2 (de) |
DK (1) | DK0501882T3 (de) |
ES (1) | ES2149166T3 (de) |
GR (1) | GR3034509T3 (de) |
HU (1) | HU214453B (de) |
IE (1) | IE920648A1 (de) |
PL (1) | PL296623A1 (de) |
PT (1) | PT501882E (de) |
SK (1) | SK282056B6 (de) |
TW (1) | TW221674B (de) |
UA (1) | UA40570C2 (de) |
WO (1) | WO1992015330A1 (de) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5688506A (en) | 1994-01-27 | 1997-11-18 | Aphton Corp. | Immunogens against gonadotropin releasing hormone |
US6761890B1 (en) * | 1995-06-07 | 2004-07-13 | Pepscan Systems B.V. | Peptide, immunogenic composition and vaccine or medical preparation, a method to immunize animals against the hormone LHRH, and analogs of the LHRH tandem repeat peptide and their use as vaccine |
CU22627A1 (es) * | 1996-12-17 | 2000-12-22 | Ct Ingenieria Genetica Biotech | Preparado vacunal para la inmuno-castración reversible de mamíferos |
AUPO776897A0 (en) * | 1997-07-09 | 1997-07-31 | Csl Limited | A method of achieving production gains in livestock and agents useful for same |
US6524592B2 (en) * | 1997-10-17 | 2003-02-25 | American Home Products Corporation | Veterinary vaccines |
US20080050367A1 (en) | 1998-04-07 | 2008-02-28 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
TWI239847B (en) | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
US7964192B1 (en) | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
US7790856B2 (en) | 1998-04-07 | 2010-09-07 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize beta amyloid peptide |
AU770409B2 (en) * | 1998-05-05 | 2004-02-19 | Metamorphix International, Inc. | Methods of raising animals for meat production |
US6626871B1 (en) | 1999-10-11 | 2003-09-30 | Felton International, Inc. | Method and apparatus for removing cap from medical device |
US6770054B1 (en) | 1999-11-23 | 2004-08-03 | Felton International, Inc. | Injector assembly with driving means and locking means |
US7887506B1 (en) | 1999-11-23 | 2011-02-15 | Pulse Needlefree Systems, Inc. | Safety mechanism to prevent accidental patient injection and methods of same |
MY139983A (en) | 2002-03-12 | 2009-11-30 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
AU2003262379A1 (en) * | 2002-04-16 | 2003-11-03 | Auburn University | TRANSIENT AND/OR PERMANENT MODIFICATION OF SEXUAL BEHAVIOR AND/OR FERTILITY USING RECOMBINANT CHIMERIC GnRH |
SG173223A1 (en) | 2003-04-22 | 2011-08-29 | Ipsen Pharma Sas | Peptide vectors |
JP2005098877A (ja) * | 2003-09-25 | 2005-04-14 | Hitachi Software Eng Co Ltd | 抗体検出体、その製造方法、及び抗体検出方法 |
NZ554332A (en) * | 2004-09-10 | 2010-01-29 | Queensland Inst Med Res | Truncated LHRH formulations with T helper cell epitopes |
CA2590337C (en) | 2004-12-15 | 2017-07-11 | Neuralab Limited | Humanized amyloid beta antibodies for use in improving cognition |
KR100701550B1 (ko) * | 2005-05-24 | 2007-03-30 | 한국과학기술연구원 | 베어링리스 스텝모터 |
WO2009017467A1 (en) | 2007-07-27 | 2009-02-05 | Elan Pharma International Limited | Treatment of amyloidogenic diseases |
US8784810B2 (en) | 2006-04-18 | 2014-07-22 | Janssen Alzheimer Immunotherapy | Treatment of amyloidogenic diseases |
JP5752343B2 (ja) * | 2007-01-24 | 2015-07-22 | 株式会社ココカラファインネクスト | S/o型経皮免疫剤 |
US8003097B2 (en) | 2007-04-18 | 2011-08-23 | Janssen Alzheimer Immunotherapy | Treatment of cerebral amyloid angiopathy |
JO3076B1 (ar) | 2007-10-17 | 2017-03-15 | Janssen Alzheimer Immunotherap | نظم العلاج المناعي المعتمد على حالة apoe |
US9067981B1 (en) | 2008-10-30 | 2015-06-30 | Janssen Sciences Ireland Uc | Hybrid amyloid-beta antibodies |
US10920242B2 (en) | 2011-02-25 | 2021-02-16 | Recombinetics, Inc. | Non-meiotic allele introgression |
CA2837375C (en) | 2011-06-01 | 2019-07-16 | Merial Limited | Needle-free administration of prrsv vaccines |
EP2914714A4 (de) * | 2012-10-30 | 2016-09-21 | Recombinetics Inc | Steuerung der geschlechtsreife bei tieren |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4010125A (en) * | 1975-06-12 | 1977-03-01 | Schally Andrew Victor | [D-Trp6 ]-LH-RH and intermediates therefor |
US4018726A (en) * | 1975-06-12 | 1977-04-19 | Andrew Victor Schally | [D-Phe6 ]-LH-RH and intermediates therefor |
US4024121A (en) * | 1976-01-27 | 1977-05-17 | Schally Andrew Victor | (Pyro)-Glu-His-Trp-D-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHR and intermediates |
US4770874A (en) * | 1983-08-22 | 1988-09-13 | Syntex (U.S.A.) Inc. | Polyoxypropylene-polyoxyethylene block polymer based adjuvants |
US4676981A (en) * | 1984-02-07 | 1987-06-30 | University Of Saskatchewan | Monoclonal antibodies against GnRH |
US4608251A (en) * | 1984-11-09 | 1986-08-26 | Pitman-Moore, Inc. | LHRH analogues useful in stimulating anti-LHRH antibodies and vaccines containing such analogues |
US4556555A (en) * | 1985-01-25 | 1985-12-03 | North Carolina State University | Process for the immunological neutering of animals |
IL78775A (en) * | 1985-05-15 | 1992-06-21 | Biotech Australia Pty Ltd | Oral vaccines |
NZ220932A (en) * | 1986-07-03 | 1990-05-28 | Victoria State | Composition comprising an antigenic substance, such as lhrh, conjugated to at least two different carriers and method of immunological castration and spaying |
JPH01500663A (ja) * | 1986-08-18 | 1989-03-09 | バンジ・(オーストラリア)・プロプライアタリー・リミテッド | 動物の生殖機能の調節 |
AU602187B2 (en) * | 1987-01-14 | 1990-10-04 | Commonwealth Scientific And Industrial Research Organisation | Anti-reproductive hormone |
GB8713240D0 (en) * | 1987-06-05 | 1987-07-08 | Proteus Biotech Ltd | Hormones |
US4975420A (en) * | 1987-09-30 | 1990-12-04 | University Of Saskatchewan | Agents and procedures for provoking an immune response to GnRH and immuno sterilizing mammals |
US5036047A (en) * | 1988-09-29 | 1991-07-30 | Pitman-Moore, Inc. | Method and composition for preventing conception |
NL8900726A (nl) * | 1989-03-23 | 1990-10-16 | Stichting Centr Diergeneeskund | Peptide, immunogene samenstelling en vaccin- of geneesmiddelpreparaat; werkwijze voor het immuniseren van een zoogdier tegen lhrh, en werkwijze voor het verbeteren van de vleeskwaliteit van varkens. |
US5484592A (en) * | 1989-03-23 | 1996-01-16 | Stitching Centraal Diergeneeskundig Instituut | Peptide, immunogenic composition and vaccine or medicinal preparation: a method of immunising a mammal against LHRH, and a method of improving the meat quality of pigs |
-
1992
- 1992-02-26 JP JP50689392A patent/JP3177246B2/ja not_active Expired - Lifetime
- 1992-02-26 WO PCT/FR1992/000176 patent/WO1992015330A1/fr active IP Right Grant
- 1992-02-26 HU HU9203419A patent/HU214453B/hu unknown
- 1992-02-26 KR KR1019920702707A patent/KR100257214B1/ko not_active IP Right Cessation
- 1992-02-26 DK DK92400496T patent/DK0501882T3/da active
- 1992-02-26 ES ES92400496T patent/ES2149166T3/es not_active Expired - Lifetime
- 1992-02-26 CA CA002081660A patent/CA2081660C/en not_active Expired - Lifetime
- 1992-02-26 AT AT92400496T patent/ATE194625T1/de active
- 1992-02-26 PL PL29662392A patent/PL296623A1/xx unknown
- 1992-02-26 DE DE69231232T patent/DE69231232T2/de not_active Expired - Lifetime
- 1992-02-26 UA UA93004193A patent/UA40570C2/uk unknown
- 1992-02-26 SK SK3280-92A patent/SK282056B6/sk not_active IP Right Cessation
- 1992-02-26 PT PT92400496T patent/PT501882E/pt unknown
- 1992-02-26 EP EP92400496A patent/EP0501882B1/de not_active Expired - Lifetime
- 1992-02-28 IE IE064892A patent/IE920648A1/en not_active IP Right Cessation
- 1992-03-05 TW TW081101687A patent/TW221674B/zh active
- 1992-10-30 CZ CZ19923280A patent/CZ287775B6/cs not_active IP Right Cessation
-
1994
- 1994-11-17 US US08/343,883 patent/US5573767A/en not_active Expired - Fee Related
-
2000
- 2000-09-28 GR GR20000402199T patent/GR3034509T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
CZ287775B6 (cs) | 2001-01-17 |
PT501882E (pt) | 2000-12-29 |
ATE194625T1 (de) | 2000-07-15 |
ES2149166T3 (es) | 2000-11-01 |
EP0501882A3 (en) | 1992-10-14 |
HUT63338A (en) | 1993-08-30 |
EP0501882A2 (de) | 1992-09-02 |
EP0501882B1 (de) | 2000-07-12 |
UA40570C2 (uk) | 2001-08-15 |
US5573767A (en) | 1996-11-12 |
SK282056B6 (sk) | 2001-10-08 |
DK0501882T3 (da) | 2000-12-11 |
TW221674B (de) | 1994-03-11 |
JP3177246B2 (ja) | 2001-06-18 |
KR100257214B1 (ko) | 2000-05-15 |
SK328092A3 (en) | 1995-01-05 |
PL296623A1 (en) | 1993-09-20 |
HU214453B (hu) | 1998-03-30 |
DE69231232D1 (de) | 2000-08-17 |
IE920648A1 (en) | 1992-09-09 |
CA2081660A1 (en) | 1992-09-02 |
WO1992015330A1 (fr) | 1992-09-17 |
JPH05506459A (ja) | 1993-09-22 |
CZ328092A3 (en) | 1993-10-13 |
CA2081660C (en) | 2001-05-01 |
GR3034509T3 (en) | 2000-12-29 |
HU9203419D0 (en) | 1993-01-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent |