DE69200304T2 - Imidazopyridin-PAF/H1-Antagonisten. - Google Patents

Imidazopyridin-PAF/H1-Antagonisten.

Info

Publication number
DE69200304T2
DE69200304T2 DE69200304T DE69200304T DE69200304T2 DE 69200304 T2 DE69200304 T2 DE 69200304T2 DE 69200304 T DE69200304 T DE 69200304T DE 69200304 T DE69200304 T DE 69200304T DE 69200304 T2 DE69200304 T2 DE 69200304T2
Authority
DE
Germany
Prior art keywords
pyrid
formula
compound
piperidine
methylimidazo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69200304T
Other languages
German (de)
English (en)
Other versions
DE69200304D1 (de
Inventor
David Alker
Robert John Bass
Kelvin Cooper
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp Belgium
Original Assignee
Pfizer Corp Belgium
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp Belgium filed Critical Pfizer Corp Belgium
Publication of DE69200304D1 publication Critical patent/DE69200304D1/de
Application granted granted Critical
Publication of DE69200304T2 publication Critical patent/DE69200304T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Prostheses (AREA)
  • Cosmetics (AREA)
  • Steroid Compounds (AREA)
DE69200304T 1991-02-13 1992-01-24 Imidazopyridin-PAF/H1-Antagonisten. Expired - Fee Related DE69200304T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919102997A GB9102997D0 (en) 1991-02-13 1991-02-13 Therapeutic agents
PCT/EP1992/000163 WO1992014734A1 (en) 1991-02-13 1992-01-24 Imidazopyridine paf/h1 antagonists

Publications (2)

Publication Number Publication Date
DE69200304D1 DE69200304D1 (de) 1994-09-08
DE69200304T2 true DE69200304T2 (de) 1994-12-08

Family

ID=10689943

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69200304T Expired - Fee Related DE69200304T2 (de) 1991-02-13 1992-01-24 Imidazopyridin-PAF/H1-Antagonisten.

Country Status (29)

Country Link
US (1) US5358953A (enExample)
EP (1) EP0572425B1 (enExample)
JP (1) JP2506541B2 (enExample)
KR (1) KR970005302B1 (enExample)
CN (1) CN1040326C (enExample)
AT (1) ATE109482T1 (enExample)
AU (1) AU650322B2 (enExample)
BR (1) BR9205615A (enExample)
CA (1) CA2099381C (enExample)
CZ (1) CZ280504B6 (enExample)
DE (1) DE69200304T2 (enExample)
DK (1) DK0572425T3 (enExample)
EG (1) EG20085A (enExample)
ES (1) ES2059212T3 (enExample)
FI (1) FI933531A7 (enExample)
GB (1) GB9102997D0 (enExample)
HU (2) HUT65947A (enExample)
IE (1) IE65125B1 (enExample)
IL (1) IL100887A (enExample)
MX (1) MX9200589A (enExample)
MY (1) MY108437A (enExample)
NO (1) NO300592B1 (enExample)
NZ (1) NZ241597A (enExample)
PL (1) PL169304B1 (enExample)
RU (1) RU2114845C1 (enExample)
TW (1) TW227000B (enExample)
WO (1) WO1992014734A1 (enExample)
YU (1) YU48238B (enExample)
ZA (1) ZA921005B (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2042421B1 (es) * 1992-05-22 1994-08-01 Uriach & Cia Sa J Procedimiento para la obtencion de la 8-cloro-11-*1-*(5-metil-3-piridil)metil*-4-piperidiliden*-6,11-dihidro-5h-benzo*5,6*ciclohepta*1,2-b*piridina.
EP0775139A1 (en) * 1994-08-10 1997-05-28 British Biotech Pharmaceuticals Limited Imidazopyridine derivatives as dual histamine (h1) and platelet activating factor (paf) antagonists
ES2087038B1 (es) * 1994-11-07 1997-03-16 Uriach & Cia Sa J Nuevas piperidinas con actividad antagonista del paf.
US5567711A (en) * 1995-04-19 1996-10-22 Abbott Laboratories Indole-3-carbonyl and indole-3-sulfonyl derivatives as platelet activating factor antagonists
GB9508748D0 (en) * 1995-04-28 1995-06-14 British Biotech Pharm Benzimidazole derivatives
JPH11510180A (ja) * 1995-08-05 1999-09-07 ブリティッシュ バイオテック ファーマシューティカルズ リミテッド イミダゾピリジン誘導体
SE9801526D0 (sv) * 1998-04-29 1998-04-29 Astra Ab New compounds
DK1311269T3 (da) 2000-08-04 2012-03-26 Dmi Biosciences Inc Fremgangsmåde til anvendelse af diketopiperaziner og sammensætning, som indeholder dem
ES2572975T3 (es) 2003-05-15 2016-06-03 Ampio Pharmaceuticals, Inc. Tratamiento de enfermedades mediadas por los linfocitos T
US7687515B2 (en) * 2006-01-17 2010-03-30 N.V. Organon 6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
AU2008349239B2 (en) 2008-01-30 2012-12-06 Nippon Zoki Pharmaceutical Co., Ltd. Piperidine derivative
WO2009146320A1 (en) 2008-05-27 2009-12-03 Dmi Life Sciences, Inc. Therapeutic methods and compounds
US9296731B2 (en) * 2011-06-28 2016-03-29 Fujian Mindong Rejuvenation Pharmaceutical Co., Ltd. Anti-allergy benzocycloheptathiophene derivatives
BR112014007675A2 (pt) 2011-10-10 2017-04-18 Ampio Pharmaceuticals Inc tratamento de doença articular degenerativa
BR112014007657A2 (pt) 2011-10-10 2017-04-11 Ampio Pharmaceuticals Inc dispositivos médicos implantáveis com tolerância imune aperfeiçoada e métodos para produção e implantação
WO2013063413A1 (en) * 2011-10-28 2013-05-02 Ampio Pharmaceuticals, Inc. Treatment of rhinitis
US9808454B2 (en) 2013-03-15 2017-11-07 Ampio Pharmaceuticals, Inc. Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
EP3183240A4 (en) 2014-08-18 2018-06-27 Ampio Pharmaceuticals, Inc. Treatment of joint conditions
HK1246669A1 (zh) 2015-06-22 2018-09-14 Ampio Pharmaceuticals, Inc. 人血清白蛋白低分子量组分在疾病治疗中的应用
CN113880801A (zh) * 2020-07-03 2022-01-04 合肥医工医药股份有限公司 一类三环化合物、其制备方法及其医药用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL132137C (enExample) * 1963-04-24
WO1989008653A1 (en) * 1988-03-15 1989-09-21 G.D. Searle & Co. 1H/3H-[4-(N,N-DICYCLOALKYL/BRANCHED-ALKYLCARBOXAMIDO)-BENZYL]IMIDAZO[4,5-c]PYRIDINES AS PAF ANTAGONISTS
DE68926976T2 (de) * 1988-04-28 1997-02-27 Schering Corp Kondensierte polyzyklische Verbindungen, Zusammenstellungen, Verfahren zur Herstellung und deren Anwendung als PAF-antagonistische, antihistaminische und/oder anti-inflammatorische Agenzien
US5250681A (en) * 1988-06-02 1993-10-05 Ajinomoto Co., Inc. Piperidine derivatives and hypotensives containing the same
US5114919A (en) * 1990-02-26 1992-05-19 Merck & Co., Inc. Adjuncts in cancer chemotherapy
RO109450B1 (ro) * 1990-05-09 1995-02-28 Pfizer Derivati de imidazo (4,5-c) piridine, procedee de obtinere, compozitii care ii contin si metoda de tratament

Also Published As

Publication number Publication date
RU2114845C1 (ru) 1998-07-10
EP0572425B1 (en) 1994-08-03
GB9102997D0 (en) 1991-03-27
MX9200589A (es) 1992-10-01
FI933531A0 (fi) 1993-08-10
NO932889D0 (no) 1993-08-13
CN1040326C (zh) 1998-10-21
AU650322B2 (en) 1994-06-16
NO300592B1 (no) 1997-06-23
KR970005302B1 (ko) 1997-04-15
AU1168392A (en) 1992-09-15
BR9205615A (pt) 1994-05-17
DE69200304D1 (de) 1994-09-08
US5358953A (en) 1994-10-25
CZ280504B6 (cs) 1996-02-14
YU48238B (sh) 1997-08-22
CN1064275A (zh) 1992-09-09
JP2506541B2 (ja) 1996-06-12
FI933531L (fi) 1993-08-10
IL100887A0 (en) 1992-11-15
DK0572425T3 (da) 1994-09-12
HU211202A9 (en) 1995-11-28
PL169304B1 (pl) 1996-06-28
HU9302327D0 (en) 1993-10-28
EP0572425A1 (en) 1993-12-08
JPH06504992A (ja) 1994-06-09
ZA921005B (en) 1993-08-12
MY108437A (en) 1996-09-30
ATE109482T1 (de) 1994-08-15
IE920449A1 (en) 1992-08-12
ES2059212T3 (es) 1994-11-01
NZ241597A (en) 1993-04-28
NO932889L (no) 1993-08-13
FI933531A7 (fi) 1993-08-10
CA2099381A1 (en) 1992-08-14
HUT65947A (en) 1994-08-29
IL100887A (en) 1996-01-19
WO1992014734A1 (en) 1992-09-03
YU14392A (sh) 1994-11-15
TW227000B (enExample) 1994-07-21
IE65125B1 (en) 1995-10-04
CS42592A3 (en) 1992-09-16
CA2099381C (en) 1996-07-09
EG20085A (en) 1997-05-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee