RU2114845C1 - Производные имидазопиридина или их фармацевтически приемлемые соли, способ их получения и фармацевтическая композиция, проявляющая антагонистическую активность в отношении гистамина (h1) - Google Patents

Производные имидазопиридина или их фармацевтически приемлемые соли, способ их получения и фармацевтическая композиция, проявляющая антагонистическую активность в отношении гистамина (h1) Download PDF

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RU2114845C1
RU2114845C1 RU93054165A RU93054165A RU2114845C1 RU 2114845 C1 RU2114845 C1 RU 2114845C1 RU 93054165 A RU93054165 A RU 93054165A RU 93054165 A RU93054165 A RU 93054165A RU 2114845 C1 RU2114845 C1 RU 2114845C1
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Russia
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pyrid
compound
formula
pharmaceutically acceptable
piperidine
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RU93054165A
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English (en)
Russian (ru)
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RU93054165A (ru
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Алкер Дэвид
Джон Басс Роберт
Купер Келвин
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Пфайзер Инк.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Prostheses (AREA)
  • Steroid Compounds (AREA)
  • Cosmetics (AREA)
RU93054165A 1991-02-13 1992-01-24 Производные имидазопиридина или их фармацевтически приемлемые соли, способ их получения и фармацевтическая композиция, проявляющая антагонистическую активность в отношении гистамина (h1) RU2114845C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919102997A GB9102997D0 (en) 1991-02-13 1991-02-13 Therapeutic agents
GB9102997.5 1991-02-13

Publications (2)

Publication Number Publication Date
RU93054165A RU93054165A (ru) 1996-09-10
RU2114845C1 true RU2114845C1 (ru) 1998-07-10

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RU93054165A RU2114845C1 (ru) 1991-02-13 1992-01-24 Производные имидазопиридина или их фармацевтически приемлемые соли, способ их получения и фармацевтическая композиция, проявляющая антагонистическую активность в отношении гистамина (h1)

Country Status (29)

Country Link
US (1) US5358953A (enExample)
EP (1) EP0572425B1 (enExample)
JP (1) JP2506541B2 (enExample)
KR (1) KR970005302B1 (enExample)
CN (1) CN1040326C (enExample)
AT (1) ATE109482T1 (enExample)
AU (1) AU650322B2 (enExample)
BR (1) BR9205615A (enExample)
CA (1) CA2099381C (enExample)
CZ (1) CZ280504B6 (enExample)
DE (1) DE69200304T2 (enExample)
DK (1) DK0572425T3 (enExample)
EG (1) EG20085A (enExample)
ES (1) ES2059212T3 (enExample)
FI (1) FI933531L (enExample)
GB (1) GB9102997D0 (enExample)
HU (2) HUT65947A (enExample)
IE (1) IE65125B1 (enExample)
IL (1) IL100887A (enExample)
MX (1) MX9200589A (enExample)
MY (1) MY108437A (enExample)
NO (1) NO300592B1 (enExample)
NZ (1) NZ241597A (enExample)
PL (1) PL169304B1 (enExample)
RU (1) RU2114845C1 (enExample)
TW (1) TW227000B (enExample)
WO (1) WO1992014734A1 (enExample)
YU (1) YU48238B (enExample)
ZA (1) ZA921005B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2235725C2 (ru) * 1998-04-29 2004-09-10 Астразенека Аб Производные имидазопиридина, способ их получения и промежуточные соединения, фармацевтический препарат на их основе (варианты), способ ингибирования секреции желудочной кислоты и способ лечения состояний, в которые вовлечено инфицирование h.pylori

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ES2042421B1 (es) * 1992-05-22 1994-08-01 Uriach & Cia Sa J Procedimiento para la obtencion de la 8-cloro-11-*1-*(5-metil-3-piridil)metil*-4-piperidiliden*-6,11-dihidro-5h-benzo*5,6*ciclohepta*1,2-b*piridina.
EP0775139A1 (en) * 1994-08-10 1997-05-28 British Biotech Pharmaceuticals Limited Imidazopyridine derivatives as dual histamine (h1) and platelet activating factor (paf) antagonists
ES2087038B1 (es) * 1994-11-07 1997-03-16 Uriach & Cia Sa J Nuevas piperidinas con actividad antagonista del paf.
US5567711A (en) * 1995-04-19 1996-10-22 Abbott Laboratories Indole-3-carbonyl and indole-3-sulfonyl derivatives as platelet activating factor antagonists
GB9508748D0 (en) * 1995-04-28 1995-06-14 British Biotech Pharm Benzimidazole derivatives
AU698487B2 (en) * 1995-08-05 1998-10-29 British Biotech Pharmaceuticals Limited Imidazopyridine derivatives
DK1311269T3 (da) 2000-08-04 2012-03-26 Dmi Biosciences Inc Fremgangsmåde til anvendelse af diketopiperaziner og sammensætning, som indeholder dem
ES2572975T3 (es) 2003-05-15 2016-06-03 Ampio Pharmaceuticals, Inc. Tratamiento de enfermedades mediadas por los linfocitos T
US7687515B2 (en) * 2006-01-17 2010-03-30 N.V. Organon 6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
CN101932575B (zh) 2008-01-30 2013-06-12 日本脏器制药株式会社 哌啶衍生物
JP5856843B2 (ja) 2008-05-27 2016-02-10 アンピオ ファーマシューティカルズ，インコーポレイテッド ジケトピペラジンを用いた医薬組成物
JP5978296B2 (ja) * 2011-06-28 2016-08-24 フジアン・ミンドン・レジュヴネイション・ファーマスーティカル・カンパニー・リミテッド 抗アレルギ性ベンゾシクロヘプタチオフェン誘導体
US9925300B2 (en) 2011-10-10 2018-03-27 Ampio Pharmaceuticals, Inc. Implantable medical devices with increased immune tolerance, and methods for making and implanting
PH12014500685B1 (en) 2011-10-10 2018-10-03 Ampio Pharmaceuticals Inc Treatment of degenerative joint disease
JP6231484B2 (ja) * 2011-10-28 2017-11-15 アンピオ ファーマシューティカルズ，インコーポレイテッド 鼻炎の処置
CN105101965B (zh) 2013-03-15 2021-03-09 安皮奥制药股份有限公司 用于干细胞活动化、归巢、扩增和分化的组合物及其使用方法
JP6723222B2 (ja) 2014-08-18 2020-07-15 アンピオ ファーマシューティカルズ，インコーポレイテッド 関節病態の治療
US11389512B2 (en) 2015-06-22 2022-07-19 Ampio Pharmaceuticals, Inc. Use of low molecular weight fractions of human serum albumin in treating diseases
CN113880801A (zh) * 2020-07-03 2022-01-04 合肥医工医药股份有限公司 一类三环化合物、其制备方法及其医药用途

Citations (1)

* Cited by examiner, † Cited by third party
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US3326924A (en) * 1963-04-24 1967-06-20 Schering Corp Novel aza-dibenzo[a, d]-cycloheptene derivatives

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JPH03503889A (ja) * 1988-03-15 1991-08-29 ジー．ディー．サール　アンド　カンパニー ＰＡＦ拮抗剤としての１Ｈ／３Ｈ‐［４‐（Ｎ，Ｎ‐ジシクロアルキル／分枝アルキルカルボキサミド）‐ベンジル］イミダゾ［４，５‐ｃ］ピリジン類
JP2511550B2 (ja) * 1988-04-28 1996-06-26 シェリング・コーポレーション 融合多環式化合物、組成物、製造方法およびｐａｆ拮抗、抗ヒスタミンおよび／または抗炎症剤としてのその使用
US5250681A (en) * 1988-06-02 1993-10-05 Ajinomoto Co., Inc. Piperidine derivatives and hypotensives containing the same
US5114919A (en) * 1990-02-26 1992-05-19 Merck & Co., Inc. Adjuncts in cancer chemotherapy
AU642265B2 (en) * 1990-05-09 1993-10-14 Pfizer Inc. Imidazo (4,5-c) pyridines with PAF antagonist activity

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3326924A (en) * 1963-04-24 1967-06-20 Schering Corp Novel aza-dibenzo[a, d]-cycloheptene derivatives

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2235725C2 (ru) * 1998-04-29 2004-09-10 Астразенека Аб Производные имидазопиридина, способ их получения и промежуточные соединения, фармацевтический препарат на их основе (варианты), способ ингибирования секреции желудочной кислоты и способ лечения состояний, в которые вовлечено инфицирование h.pylori
RU2238271C2 (ru) * 1998-04-29 2004-10-20 Астразенека Аб Производные имидазопиридина, способы их получения и промежуточные соединения, фармацевтический препарат на их основе (варианты), способ ингибирования секреции желудочной кислоты, способ лечения желудочно-кишечных воспалительных заболеваний и способ лечения состояний, в которых вовлечено инфицирование h.pylori

Also Published As

Publication number Publication date
AU650322B2 (en) 1994-06-16
ATE109482T1 (de) 1994-08-15
AU1168392A (en) 1992-09-15
BR9205615A (pt) 1994-05-17
YU48238B (sh) 1997-08-22
DE69200304T2 (de) 1994-12-08
CZ280504B6 (cs) 1996-02-14
FI933531A7 (fi) 1993-08-10
PL169304B1 (pl) 1996-06-28
FI933531A0 (fi) 1993-08-10
FI933531L (fi) 1993-08-10
CS42592A3 (en) 1992-09-16
US5358953A (en) 1994-10-25
ZA921005B (en) 1993-08-12
HU9302327D0 (en) 1993-10-28
DE69200304D1 (de) 1994-09-08
HU211202A9 (en) 1995-11-28
CA2099381A1 (en) 1992-08-14
ES2059212T3 (es) 1994-11-01
NZ241597A (en) 1993-04-28
MY108437A (en) 1996-09-30
IL100887A (en) 1996-01-19
IE920449A1 (en) 1992-08-12
JP2506541B2 (ja) 1996-06-12
IE65125B1 (en) 1995-10-04
CN1040326C (zh) 1998-10-21
YU14392A (sh) 1994-11-15
EG20085A (en) 1997-05-31
GB9102997D0 (en) 1991-03-27
NO300592B1 (no) 1997-06-23
IL100887A0 (en) 1992-11-15
TW227000B (enExample) 1994-07-21
EP0572425B1 (en) 1994-08-03
EP0572425A1 (en) 1993-12-08
HUT65947A (en) 1994-08-29
MX9200589A (es) 1992-10-01
NO932889D0 (no) 1993-08-13
WO1992014734A1 (en) 1992-09-03
KR970005302B1 (ko) 1997-04-15
DK0572425T3 (da) 1994-09-12
CN1064275A (zh) 1992-09-09
JPH06504992A (ja) 1994-06-09
NO932889L (no) 1993-08-13
CA2099381C (en) 1996-07-09

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