RU2114845C1 - Производные имидазопиридина или их фармацевтически приемлемые соли, способ их получения и фармацевтическая композиция, проявляющая антагонистическую активность в отношении гистамина (h1) - Google Patents

Производные имидазопиридина или их фармацевтически приемлемые соли, способ их получения и фармацевтическая композиция, проявляющая антагонистическую активность в отношении гистамина (h1) Download PDF

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Publication number
RU2114845C1
RU2114845C1 RU93054165A RU93054165A RU2114845C1 RU 2114845 C1 RU2114845 C1 RU 2114845C1 RU 93054165 A RU93054165 A RU 93054165A RU 93054165 A RU93054165 A RU 93054165A RU 2114845 C1 RU2114845 C1 RU 2114845C1
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Russia
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pyrid
compound
formula
pharmaceutically acceptable
piperidine
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RU93054165A
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English (en)
Russian (ru)
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RU93054165A (ru
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Алкер Дэвид
Джон Басс Роберт
Купер Келвин
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Пфайзер Инк.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Prostheses (AREA)
  • Steroid Compounds (AREA)
  • Cosmetics (AREA)
RU93054165A 1991-02-13 1992-01-24 Производные имидазопиридина или их фармацевтически приемлемые соли, способ их получения и фармацевтическая композиция, проявляющая антагонистическую активность в отношении гистамина (h1) RU2114845C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9102997.5 1991-02-13
GB919102997A GB9102997D0 (en) 1991-02-13 1991-02-13 Therapeutic agents

Publications (2)

Publication Number Publication Date
RU93054165A RU93054165A (ru) 1996-09-10
RU2114845C1 true RU2114845C1 (ru) 1998-07-10

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Family Applications (1)

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RU93054165A RU2114845C1 (ru) 1991-02-13 1992-01-24 Производные имидазопиридина или их фармацевтически приемлемые соли, способ их получения и фармацевтическая композиция, проявляющая антагонистическую активность в отношении гистамина (h1)

Country Status (29)

Country Link
US (1) US5358953A (enExample)
EP (1) EP0572425B1 (enExample)
JP (1) JP2506541B2 (enExample)
KR (1) KR970005302B1 (enExample)
CN (1) CN1040326C (enExample)
AT (1) ATE109482T1 (enExample)
AU (1) AU650322B2 (enExample)
BR (1) BR9205615A (enExample)
CA (1) CA2099381C (enExample)
CZ (1) CZ280504B6 (enExample)
DE (1) DE69200304T2 (enExample)
DK (1) DK0572425T3 (enExample)
EG (1) EG20085A (enExample)
ES (1) ES2059212T3 (enExample)
FI (1) FI933531L (enExample)
GB (1) GB9102997D0 (enExample)
HU (2) HUT65947A (enExample)
IE (1) IE65125B1 (enExample)
IL (1) IL100887A (enExample)
MX (1) MX9200589A (enExample)
MY (1) MY108437A (enExample)
NO (1) NO300592B1 (enExample)
NZ (1) NZ241597A (enExample)
PL (1) PL169304B1 (enExample)
RU (1) RU2114845C1 (enExample)
TW (1) TW227000B (enExample)
WO (1) WO1992014734A1 (enExample)
YU (1) YU48238B (enExample)
ZA (1) ZA921005B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2235725C2 (ru) * 1998-04-29 2004-09-10 Астразенека Аб Производные имидазопиридина, способ их получения и промежуточные соединения, фармацевтический препарат на их основе (варианты), способ ингибирования секреции желудочной кислоты и способ лечения состояний, в которые вовлечено инфицирование h.pylori

Families Citing this family (19)

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ES2042421B1 (es) * 1992-05-22 1994-08-01 Uriach & Cia Sa J Procedimiento para la obtencion de la 8-cloro-11-*1-*(5-metil-3-piridil)metil*-4-piperidiliden*-6,11-dihidro-5h-benzo*5,6*ciclohepta*1,2-b*piridina.
EP0775139A1 (en) * 1994-08-10 1997-05-28 British Biotech Pharmaceuticals Limited Imidazopyridine derivatives as dual histamine (h1) and platelet activating factor (paf) antagonists
ES2087038B1 (es) * 1994-11-07 1997-03-16 Uriach & Cia Sa J Nuevas piperidinas con actividad antagonista del paf.
US5866588A (en) * 1995-04-05 1999-02-02 British Biotech Pharmaceuticals Ltd. Imidazopyridine derivatives
US5567711A (en) * 1995-04-19 1996-10-22 Abbott Laboratories Indole-3-carbonyl and indole-3-sulfonyl derivatives as platelet activating factor antagonists
GB9508748D0 (en) * 1995-04-28 1995-06-14 British Biotech Pharm Benzimidazole derivatives
CA2417960C (en) 2000-08-04 2012-07-10 Dmi Biosciences, Inc. Method of using diketopiperazines and composition containing them
ES2579635T3 (es) 2003-05-15 2016-08-12 Ampio Pharmaceuticals, Inc. Tratamiento de enfermedades mediadas por los linfocitos T
US7687515B2 (en) * 2006-01-17 2010-03-30 N.V. Organon 6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
AU2008349239B2 (en) 2008-01-30 2012-12-06 Nippon Zoki Pharmaceutical Co., Ltd. Piperidine derivative
JP5856843B2 (ja) 2008-05-27 2016-02-10 アンピオ ファーマシューティカルズ，インコーポレイテッド ジケトピペラジンを用いた医薬組成物
EP2727919B1 (en) * 2011-06-28 2019-05-08 Fujian Mindong Rejuvenation Pharmaceutical Co., Ltd. Benzocycloheptanethiophene derivatives for anti-allergic reactions
SG10201608087WA (en) 2011-10-10 2016-11-29 Ampio Pharmaceuticals Inc Implantable medical devices with increased immune tolerance, and methods for making and implanting
KR102032400B1 (ko) 2011-10-10 2019-10-15 앰피오 파마슈티컬스 인코퍼레이티드 퇴행성 관절 질환의 치료
BR112014008036A2 (pt) * 2011-10-28 2017-04-11 Ampio Pharmaceuticals Inc tratamento de rinite
CA2906864A1 (en) 2013-03-15 2014-09-18 Ampio Pharmaceuticals, Inc. Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
JP6723222B2 (ja) 2014-08-18 2020-07-15 アンピオ ファーマシューティカルズ，インコーポレイテッド 関節病態の治療
EP3310375A4 (en) 2015-06-22 2019-02-20 Ampio Pharmaceuticals, Inc. USE OF LOW-MOLECULAR FRACTIONS OF HUMAN SERUMALBUMINE IN THE TREATMENT OF ILLNESSES
CN113880801A (zh) * 2020-07-03 2022-01-04 合肥医工医药股份有限公司 一类三环化合物、其制备方法及其医药用途

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3326924A (en) * 1963-04-24 1967-06-20 Schering Corp Novel aza-dibenzo[a, d]-cycloheptene derivatives

Family Cites Families (5)

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Publication number Priority date Publication date Assignee Title
JPH03503889A (ja) * 1988-03-15 1991-08-29 ジー．ディー．サール　アンド　カンパニー ＰＡＦ拮抗剤としての１Ｈ／３Ｈ‐［４‐（Ｎ，Ｎ‐ジシクロアルキル／分枝アルキルカルボキサミド）‐ベンジル］イミダゾ［４，５‐ｃ］ピリジン類
EP0339978B1 (en) * 1988-04-28 1996-08-21 Schering Corporation Fused polycyclic compounds, compositions, methods of manufacture, and their use as PAF antagonists, antihistamines and/or antiinflammatory agents
US5250681A (en) * 1988-06-02 1993-10-05 Ajinomoto Co., Inc. Piperidine derivatives and hypotensives containing the same
US5114919A (en) * 1990-02-26 1992-05-19 Merck & Co., Inc. Adjuncts in cancer chemotherapy
JPH0678340B2 (ja) * 1990-05-09 1994-10-05 フアイザー・インコーポレイテツド 喘息、関節炎および関連疾患の治療におけるアザベンジミダゾール

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3326924A (en) * 1963-04-24 1967-06-20 Schering Corp Novel aza-dibenzo[a, d]-cycloheptene derivatives

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2235725C2 (ru) * 1998-04-29 2004-09-10 Астразенека Аб Производные имидазопиридина, способ их получения и промежуточные соединения, фармацевтический препарат на их основе (варианты), способ ингибирования секреции желудочной кислоты и способ лечения состояний, в которые вовлечено инфицирование h.pylori
RU2238271C2 (ru) * 1998-04-29 2004-10-20 Астразенека Аб Производные имидазопиридина, способы их получения и промежуточные соединения, фармацевтический препарат на их основе (варианты), способ ингибирования секреции желудочной кислоты, способ лечения желудочно-кишечных воспалительных заболеваний и способ лечения состояний, в которых вовлечено инфицирование h.pylori

Also Published As

Publication number Publication date
MX9200589A (es) 1992-10-01
ATE109482T1 (de) 1994-08-15
IE65125B1 (en) 1995-10-04
ES2059212T3 (es) 1994-11-01
JP2506541B2 (ja) 1996-06-12
DE69200304D1 (de) 1994-09-08
JPH06504992A (ja) 1994-06-09
CS42592A3 (en) 1992-09-16
EG20085A (en) 1997-05-31
CN1040326C (zh) 1998-10-21
MY108437A (en) 1996-09-30
NO932889L (no) 1993-08-13
CN1064275A (zh) 1992-09-09
YU14392A (sh) 1994-11-15
EP0572425B1 (en) 1994-08-03
FI933531A0 (fi) 1993-08-10
CA2099381C (en) 1996-07-09
TW227000B (enExample) 1994-07-21
PL169304B1 (pl) 1996-06-28
HUT65947A (en) 1994-08-29
WO1992014734A1 (en) 1992-09-03
IL100887A0 (en) 1992-11-15
NZ241597A (en) 1993-04-28
KR970005302B1 (ko) 1997-04-15
NO300592B1 (no) 1997-06-23
HU211202A9 (en) 1995-11-28
HU9302327D0 (en) 1993-10-28
GB9102997D0 (en) 1991-03-27
DE69200304T2 (de) 1994-12-08
FI933531A7 (fi) 1993-08-10
IE920449A1 (en) 1992-08-12
AU1168392A (en) 1992-09-15
EP0572425A1 (en) 1993-12-08
AU650322B2 (en) 1994-06-16
YU48238B (sh) 1997-08-22
FI933531L (fi) 1993-08-10
CZ280504B6 (cs) 1996-02-14
NO932889D0 (no) 1993-08-13
CA2099381A1 (en) 1992-08-14
US5358953A (en) 1994-10-25
BR9205615A (pt) 1994-05-17
DK0572425T3 (da) 1994-09-12
IL100887A (en) 1996-01-19
ZA921005B (en) 1993-08-12

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