YU14392A - Derivati imidazopiridina, postupak za dobijanje smeša sa njima i postupak za dobijanje derivata imidazopiridina - Google Patents
Derivati imidazopiridina, postupak za dobijanje smeša sa njima i postupak za dobijanje derivata imidazopiridinaInfo
- Publication number
- YU14392A YU14392A YU14392A YU14392A YU14392A YU 14392 A YU14392 A YU 14392A YU 14392 A YU14392 A YU 14392A YU 14392 A YU14392 A YU 14392A YU 14392 A YU14392 A YU 14392A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- imidazopyridine derivatives
- formula
- obtaining
- preparing mixtures
- imidazopyridine
- Prior art date
Links
- 150000005232 imidazopyridines Chemical class 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 125000004857 imidazopyridinyl group Chemical class N1C(=NC2=C1C=CC=N2)* 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000005605 benzo group Chemical group 0.000 abstract 1
- 125000006355 carbonyl methylene group Chemical group [H]C([H])([*:2])C([*:1])=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001511 cyclopentyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 abstract 1
- 125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003053 piperidines Chemical class 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Prostheses (AREA)
- Cosmetics (AREA)
- Steroid Compounds (AREA)
Abstract
DERIVATI IMIDAZOPIRIDINA, POSTUPAK ZA DOBIJANJE SMEŠA SA NJIMA I POSTUPAK ZA DOBIJANJE DERIVATA IMIDAZOPIRIDINA, opisani su derivati imidazopiridina, jedinjenja formule; u kojoj X je CH ili N; Z je CH=CH ili S; A je CH2CH2, CH=CH, CH(OH)CH2, ili COCH2; B je direktna veza ili -CH2-, -CH(CH3)- ili -C(CH3)2-, ili kada Z je CH=CH, B može obrazovati kondenzovan ciklopentanov prsten vezan na benzenov prsten; Y kompletira kondenzovan benzo ili tienil prsten koji je po potrebi supstituisan sa halo ili C1-C4 alkil; n je 0, 1 ili 2; i m je 0 ili 1. Takodje je opisan postupak za dobijanje ovih derivata imidazopiridina koji obuhvata reakciju derivata piperidina formule (II) sa kiselinom formule (III) ili njenim aktiviranim derivatom: gde su X, Y, Z, A, B, n kao što je prethodno definisano.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919102997A GB9102997D0 (en) | 1991-02-13 | 1991-02-13 | Therapeutic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| YU14392A true YU14392A (sh) | 1994-11-15 |
| YU48238B YU48238B (sh) | 1997-08-22 |
Family
ID=10689943
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU14392A YU48238B (sh) | 1991-02-13 | 1992-02-12 | Derivti imidazopiridina, postupak za dobijanje smeša sa njima i postupak za dobijanje derivata imidazopiridina |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US5358953A (sh) |
| EP (1) | EP0572425B1 (sh) |
| JP (1) | JP2506541B2 (sh) |
| KR (1) | KR970005302B1 (sh) |
| CN (1) | CN1040326C (sh) |
| AT (1) | ATE109482T1 (sh) |
| AU (1) | AU650322B2 (sh) |
| BR (1) | BR9205615A (sh) |
| CA (1) | CA2099381C (sh) |
| CZ (1) | CZ280504B6 (sh) |
| DE (1) | DE69200304T2 (sh) |
| DK (1) | DK0572425T3 (sh) |
| EG (1) | EG20085A (sh) |
| ES (1) | ES2059212T3 (sh) |
| FI (1) | FI933531A (sh) |
| GB (1) | GB9102997D0 (sh) |
| HU (2) | HUT65947A (sh) |
| IE (1) | IE65125B1 (sh) |
| IL (1) | IL100887A (sh) |
| MX (1) | MX9200589A (sh) |
| MY (1) | MY108437A (sh) |
| NO (1) | NO300592B1 (sh) |
| NZ (1) | NZ241597A (sh) |
| PL (1) | PL169304B1 (sh) |
| RU (1) | RU2114845C1 (sh) |
| TW (1) | TW227000B (sh) |
| WO (1) | WO1992014734A1 (sh) |
| YU (1) | YU48238B (sh) |
| ZA (1) | ZA921005B (sh) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2042421B1 (es) * | 1992-05-22 | 1994-08-01 | Uriach & Cia Sa J | Procedimiento para la obtencion de la 8-cloro-11-*1-*(5-metil-3-piridil)metil*-4-piperidiliden*-6,11-dihidro-5h-benzo*5,6*ciclohepta*1,2-b*piridina. |
| AU3186395A (en) * | 1994-08-10 | 1996-03-07 | British Biotech Pharmaceuticals Limited | Imidazopyridine derivatives as dual histamine (h1) and platelet activating factor (paf) antagonists |
| ES2087038B1 (es) * | 1994-11-07 | 1997-03-16 | Uriach & Cia Sa J | Nuevas piperidinas con actividad antagonista del paf. |
| US5567711A (en) * | 1995-04-19 | 1996-10-22 | Abbott Laboratories | Indole-3-carbonyl and indole-3-sulfonyl derivatives as platelet activating factor antagonists |
| GB9508748D0 (en) * | 1995-04-28 | 1995-06-14 | British Biotech Pharm | Benzimidazole derivatives |
| BR9609892A (pt) * | 1995-08-05 | 1999-05-25 | British Biotech Pharm | Derivados de imidazopiridina |
| EP1311269B1 (en) | 2000-08-04 | 2012-02-29 | DMI Biosciences, Inc. | Method of using diketopiperazines and composition containing them |
| ES2572975T3 (es) | 2003-05-15 | 2016-06-03 | Ampio Pharmaceuticals, Inc. | Tratamiento de enfermedades mediadas por los linfocitos T |
| US7687515B2 (en) * | 2006-01-17 | 2010-03-30 | N.V. Organon | 6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives |
| TWI429641B (zh) | 2008-01-30 | 2014-03-11 | Nippon Zoki Pharmaceutical Co | 哌啶衍生物 |
| EP2300011A4 (en) | 2008-05-27 | 2012-06-20 | Dmi Life Sciences Inc | METHODS AND THERAPEUTIC COMPOUNDS |
| WO2013000406A1 (zh) * | 2011-06-28 | 2013-01-03 | Lin Tongjun | 抗-变态反应的苯并环庚并噻吩衍生物 |
| EP3721884A1 (en) | 2011-10-10 | 2020-10-14 | Ampio Pharmaceuticals, Inc. | Treatment of degenerative joint disease with da-dkp (= aspartyl-alanyl diketopiperazine) |
| US9925300B2 (en) | 2011-10-10 | 2018-03-27 | Ampio Pharmaceuticals, Inc. | Implantable medical devices with increased immune tolerance, and methods for making and implanting |
| WO2013063413A1 (en) * | 2011-10-28 | 2013-05-02 | Ampio Pharmaceuticals, Inc. | Treatment of rhinitis |
| CA2906864A1 (en) | 2013-03-15 | 2014-09-18 | Ampio Pharmaceuticals, Inc. | Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same |
| JP6723222B2 (ja) | 2014-08-18 | 2020-07-15 | アンピオ ファーマシューティカルズ，インコーポレイテッド | 関節病態の治療 |
| WO2016209969A1 (en) | 2015-06-22 | 2016-12-29 | Ampio Pharmaceuticals, Inc. | Use of low molecular weight fractions of human serum albumin in treating diseases |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03503889A (ja) * | 1988-03-15 | 1991-08-29 | ジー．ディー．サール アンド カンパニー | ＰＡＦ拮抗剤としての１Ｈ／３Ｈ‐［４‐（Ｎ，Ｎ‐ジシクロアルキル／分枝アルキルカルボキサミド）‐ベンジル］イミダゾ［４，５‐ｃ］ピリジン類 |
| ES2091195T3 (es) * | 1988-04-28 | 1996-11-01 | Schering Corp | Compuestos policiclicos condensados, composiciones, metodos de preparacion y su uso como agentes antagonistas de paf, antihistaminicos y/o antiinflamatorios. |
| US5250681A (en) * | 1988-06-02 | 1993-10-05 | Ajinomoto Co., Inc. | Piperidine derivatives and hypotensives containing the same |
| US5114919A (en) * | 1990-02-26 | 1992-05-19 | Merck & Co., Inc. | Adjuncts in cancer chemotherapy |
| RO109450B1 (ro) * | 1990-05-09 | 1995-02-28 | Pfizer | Derivati de imidazo (4,5-c) piridine, procedee de obtinere, compozitii care ii contin si metoda de tratament |
-
1991
- 1991-02-13 GB GB919102997A patent/GB9102997D0/en active Pending
-
1992
- 1992-01-24 RU RU93054165A patent/RU2114845C1/ru active
- 1992-01-24 KR KR1019930702352A patent/KR970005302B1/ko not_active IP Right Cessation
- 1992-01-24 PL PL92300296A patent/PL169304B1/pl unknown
- 1992-01-24 DK DK92902889.2T patent/DK0572425T3/da active
- 1992-01-24 HU HU9302327A patent/HUT65947A/hu unknown
- 1992-01-24 JP JP4503504A patent/JP2506541B2/ja not_active Expired - Fee Related
- 1992-01-24 DE DE69200304T patent/DE69200304T2/de not_active Expired - Fee Related
- 1992-01-24 EP EP92902889A patent/EP0572425B1/en not_active Expired - Lifetime
- 1992-01-24 BR BR9205615A patent/BR9205615A/pt not_active Application Discontinuation
- 1992-01-24 CA CA002099381A patent/CA2099381C/en not_active Expired - Fee Related
- 1992-01-24 AU AU11683/92A patent/AU650322B2/en not_active Ceased
- 1992-01-24 ES ES92902889T patent/ES2059212T3/es not_active Expired - Lifetime
- 1992-01-24 WO PCT/EP1992/000163 patent/WO1992014734A1/en active IP Right Grant
- 1992-01-24 US US08/087,736 patent/US5358953A/en not_active Expired - Fee Related
- 1992-01-24 AT AT92902889T patent/ATE109482T1/de not_active IP Right Cessation
- 1992-02-06 IL IL10088792A patent/IL100887A/en not_active IP Right Cessation
- 1992-02-10 TW TW081100891A patent/TW227000B/zh active
- 1992-02-10 EG EG8792A patent/EG20085A/xx active
- 1992-02-11 MX MX9200589A patent/MX9200589A/es unknown
- 1992-02-12 ZA ZA921005A patent/ZA921005B/xx unknown
- 1992-02-12 IE IE920449A patent/IE65125B1/en not_active IP Right Cessation
- 1992-02-12 MY MYPI92000223A patent/MY108437A/en unknown
- 1992-02-12 NZ NZ241597A patent/NZ241597A/en unknown
- 1992-02-12 YU YU14392A patent/YU48238B/sh unknown
- 1992-02-12 CZ CS92425A patent/CZ280504B6/cs not_active IP Right Cessation
- 1992-02-13 CN CN92100974A patent/CN1040326C/zh not_active Expired - Fee Related
-
1993
- 1993-08-10 FI FI933531A patent/FI933531A/fi not_active Application Discontinuation
- 1993-08-13 NO NO932889A patent/NO300592B1/no unknown
-
1995
- 1995-06-09 HU HU95P/P00175P patent/HU211202A9/hu unknown
Also Published As
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