DE69122464D1 - Transdermal absorbierbares mittel mit morphin hydrochlorid - Google Patents
Transdermal absorbierbares mittel mit morphin hydrochloridInfo
- Publication number
- DE69122464D1 DE69122464D1 DE69122464T DE69122464T DE69122464D1 DE 69122464 D1 DE69122464 D1 DE 69122464D1 DE 69122464 T DE69122464 T DE 69122464T DE 69122464 T DE69122464 T DE 69122464T DE 69122464 D1 DE69122464 D1 DE 69122464D1
- Authority
- DE
- Germany
- Prior art keywords
- morphine hydrochloride
- transdermal absorbable
- absorbable agent
- agent
- transdermal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP02081180 | 1990-03-30 | ||
PCT/JP1991/000413 WO1991015241A1 (en) | 1990-03-30 | 1991-03-29 | Percutaneously absorbable composition of narcotic and nonnarcotic analgesics |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69122464D1 true DE69122464D1 (de) | 1996-11-07 |
DE69122464T2 DE69122464T2 (de) | 1997-02-20 |
Family
ID=13739272
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69122464T Expired - Fee Related DE69122464T2 (de) | 1990-03-30 | 1991-03-29 | Transdermal absorbierbares mittel mit morphin hydrochlorid |
Country Status (7)
Country | Link |
---|---|
US (1) | US5240932A (de) |
EP (1) | EP0480054B1 (de) |
AT (1) | ATE143603T1 (de) |
AU (1) | AU7547891A (de) |
DE (1) | DE69122464T2 (de) |
ES (1) | ES2094809T3 (de) |
WO (1) | WO1991015241A1 (de) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9003665D0 (sv) * | 1990-11-16 | 1990-11-16 | Kabivitrum Ab | Morphine prodrugs |
GB9202464D0 (en) * | 1992-02-05 | 1992-03-18 | Danbiosyst Uk | Composition for nasal administration |
KR960700041A (ko) * | 1993-01-21 | 1996-01-19 | 오노다 마사요시 | 신규한 경피 흡수제제(Novel percutaneously absorbable preparation) |
US5962477A (en) * | 1994-04-12 | 1999-10-05 | Adolor Corporation | Screening methods for cytokine inhibitors |
US6190691B1 (en) | 1994-04-12 | 2001-02-20 | Adolor Corporation | Methods for treating inflammatory conditions |
US5552406A (en) * | 1994-06-17 | 1996-09-03 | The Mclean Hospital Corporation | Method for treating pain and brain perfusion abnormalities using mixed opioid agonist-antagonists |
GB9415348D0 (en) * | 1994-07-29 | 1994-09-21 | Sinclair Int Ltd | Preservation of plant material |
US5849761A (en) * | 1995-09-12 | 1998-12-15 | Regents Of The University Of California | Peripherally active anti-hyperalgesic opiates |
US6573282B1 (en) | 1995-09-12 | 2003-06-03 | Adolor Corporation | Peripherally active anti-hyperalgesic opiates |
DE19541260A1 (de) * | 1995-11-06 | 1997-05-07 | Lohmann Therapie Syst Lts | Therapeutische Zubereitung zur transdermalen Applikation von Wirkstoffen durch die Haut |
JPH1036265A (ja) * | 1996-07-19 | 1998-02-10 | Nitto Denko Corp | ブプレノルフィン経皮吸収製剤 |
KR20000075804A (ko) * | 1997-02-28 | 2000-12-26 | 스프레이그 로버트 월터 | 테스토스테론의 경피 전달 기구 |
US7150881B2 (en) | 1997-06-26 | 2006-12-19 | Mylan Technologies, Inc. | Adhesive mixture for transdermal delivery of highly plasticizing drugs |
US20030077227A1 (en) * | 1997-10-01 | 2003-04-24 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system |
US20030077228A1 (en) * | 1997-10-01 | 2003-04-24 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating endocrine disorders |
US20050180923A1 (en) * | 1997-10-01 | 2005-08-18 | Dugger Harry A.Iii | Buccal, polar and non-polar spray containing testosterone |
US20050287075A1 (en) * | 1997-10-01 | 2005-12-29 | Dugger Harry A Iii | Buccal, polar and non-polar spray or capsule containing drugs for treating pain |
US20090162300A1 (en) * | 1997-10-01 | 2009-06-25 | Dugger Iii Harry A | Buccal, polar and non-polar spray containing alprazolam |
US20040136914A1 (en) | 1997-10-01 | 2004-07-15 | Dugger Harry A. | Buccal, polar and non-polar spray containing ondansetron |
US20030190286A1 (en) * | 1997-10-01 | 2003-10-09 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating allergies or asthma |
US20030082107A1 (en) * | 1997-10-01 | 2003-05-01 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating an infectious disease or cancer |
US7632517B2 (en) * | 1997-10-01 | 2009-12-15 | Novadel Pharma Inc. | Buccal, polar and non-polar spray containing zolpidem |
US20030185761A1 (en) * | 1997-10-01 | 2003-10-02 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating pain |
US20030077229A1 (en) * | 1997-10-01 | 2003-04-24 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing cardiovascular or renal drugs |
US20040141923A1 (en) * | 1997-10-01 | 2004-07-22 | Dugger Harry A. | Buccal, polar and non-polar spray containing alprazolam |
US20030095927A1 (en) * | 1997-10-01 | 2003-05-22 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating muscular and skeletal disorders |
US20050163719A1 (en) * | 1997-10-01 | 2005-07-28 | Dugger Harry A.Iii | Buccal, polar and non-polar spray containing diazepam |
EP2042161A1 (de) * | 1997-10-01 | 2009-04-01 | Novadel Pharma Inc. | Treibmittelfreie Sprayzusammensetzung enthaltend ein Antiemetikum |
US20040136915A1 (en) * | 1997-10-01 | 2004-07-15 | Dugger Harry A. | Buccal, polar and non-polar spray containing atropine |
US20030095925A1 (en) * | 1997-10-01 | 2003-05-22 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating metabolic disorders |
US20050281752A1 (en) * | 1997-10-01 | 2005-12-22 | Dugger Harry A Iii | Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system |
US20040136913A1 (en) * | 1997-10-01 | 2004-07-15 | Dugger Harry A. | Buccal, polar and non-polar spray containing sumatriptan |
US20050002867A1 (en) * | 1997-10-01 | 2005-01-06 | Novadel Pharma Inc. | Buccal, polar and non-polar sprays containing propofol |
PT1094781E (pt) * | 1998-07-07 | 2008-10-08 | Transdermal Technologies Inc | Composições para administração transdérmica rápida e não irritante de agentes farmacologicamente activos e métodos para formulação de tais composições e sua administração |
JP4399044B2 (ja) * | 1998-10-14 | 2010-01-13 | 久光製薬株式会社 | 吸収促進剤及び該吸収促進剤を有してなる経皮吸収製剤 |
TW550080B (en) * | 1998-11-17 | 2003-09-01 | Shionogi & Co | Transdermic preparation comprising cerebral function activating agent |
US7087215B2 (en) * | 1998-12-21 | 2006-08-08 | Generex Pharmaceuticals Incorporated | Methods of administering and enhancing absorption of pharmaceutical agents |
US6849263B2 (en) * | 1998-12-21 | 2005-02-01 | Generex Pharmaceutical Incorporated | Pharmaceutical compositions for buccal delivery of pain relief medications |
CA2387953C (en) | 1999-10-14 | 2008-12-09 | Pola Chemical Industries Inc. | Compositions for electroporation |
AU3672100A (en) * | 1999-10-15 | 2001-04-23 | Pola Chemical Industries Inc. | Percutaneous absorption promoters for electroporation |
US20060121103A1 (en) * | 2000-05-11 | 2006-06-08 | Kenneth Kirby | Transdermal delivery system |
DE10256774A1 (de) * | 2002-12-05 | 2004-06-24 | Lts Lohmann Therapie-Systeme Ag | Transmucosale und transdermale Arzneimittel mit verbesserter Wirkstoffresorption |
GB0305579D0 (en) * | 2003-03-11 | 2003-04-16 | Dallas Burston Ltd | Pharmaceutical compositions |
US20060062812A1 (en) * | 2003-03-11 | 2006-03-23 | Calvin Ross | Novel compositions |
US20050244522A1 (en) * | 2004-04-30 | 2005-11-03 | Carrara Dario Norberto R | Permeation enhancer comprising genus Curcuma or germacrone for transdermal and topical administration of active agents |
US8252320B2 (en) | 2004-10-21 | 2012-08-28 | Durect Corporation | Transdermal delivery system for sufentanil |
DK2216018T3 (da) | 2004-10-21 | 2012-07-02 | Durect Corp | Transdermale leveringssystemer |
EP2015632B1 (de) * | 2006-04-19 | 2015-12-02 | Mist Pharmaceuticals, LLC | Stabile wässrig-alkoholische mundsprayformulierungen und verfahren |
US20080146672A1 (en) * | 2006-12-08 | 2008-06-19 | Denton Marcia Marye | Topical Eutectic Anesthetic Composition for Oral or Dermal Tissue |
CA2673049C (en) * | 2006-12-22 | 2016-02-23 | Novadel Pharma Inc. | Stable anti-nausea oral spray formulations and methods |
US20080280947A1 (en) * | 2007-05-10 | 2008-11-13 | Blondino Frank E | Anti-insomnia compositions and methods |
US7985325B2 (en) * | 2007-10-30 | 2011-07-26 | Novellus Systems, Inc. | Closed contact electroplating cup assembly |
EP2298313A4 (de) * | 2008-05-15 | 2013-08-21 | Nippon Zoki Pharmaceutical Co | Prochlorperazin enthaltende pharmazeutische zusammensetzung zur externen anwendung |
US8445037B2 (en) * | 2008-10-28 | 2013-05-21 | A. M. Todd Company | Volatile distillate by-product of mint oil that promotes absorption and/or bioavailability of compounds of bio-medical and nutritional interest |
RU2535095C2 (ru) * | 2013-01-09 | 2014-12-10 | Федеральное государственное бюджетное учреждение науки "Институт токсикологии Федерального медико-биологического агентства" | Композиция для трансдермальной доставки в организм лекарственных веществ и лекарственная форма на ее основе |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2631947B2 (de) * | 1976-07-15 | 1980-11-27 | Bayer Ag, 5090 Leverkusen | Verwendung von ätherischen ölen und Äthylalkohol |
JPS5636411A (en) * | 1979-08-31 | 1981-04-09 | Sumitomo Chem Co Ltd | Liquid agent for external use |
JPS5762221A (en) * | 1980-10-02 | 1982-04-15 | Lion Corp | Embrocation for external use |
JPS57206610A (en) * | 1981-06-12 | 1982-12-18 | Lion Corp | Anti-inflammatory analgesic solution for external use |
JPS5815909A (ja) * | 1981-07-22 | 1983-01-29 | Toko Yakuhin Kogyo Kk | 抗真菌外用剤 |
JPS58189115A (ja) * | 1982-04-30 | 1983-11-04 | Kowa Co | 外用剤 |
JPS59139325A (ja) * | 1982-10-19 | 1984-08-10 | Nissan Chem Ind Ltd | 透明速乾性塗布剤組成物 |
GR81250B (en) * | 1983-12-22 | 1985-11-19 | American Home Prod | Menthol enhancement of transdermal drug delivery |
DE3583698D1 (de) * | 1984-04-23 | 1991-09-12 | Kao Corp | Perkutaner absorptions-beschleuniger und diesen enthaltendes praeparat. |
JPS6112614A (ja) * | 1984-06-27 | 1986-01-21 | Lion Corp | 水性パップ剤 |
US4626539A (en) * | 1984-08-10 | 1986-12-02 | E. I. Dupont De Nemours And Company | Trandermal delivery of opioids |
JPS6233116A (ja) * | 1985-08-03 | 1987-02-13 | Hisamitsu Pharmaceut Co Inc | 外用消炎鎮痛剤 |
JP2764261B2 (ja) * | 1987-03-17 | 1998-06-11 | リ−ドケミカル株式会社 | 外用消炎鎮痛剤 |
-
1991
- 1991-03-29 AT AT91906584T patent/ATE143603T1/de not_active IP Right Cessation
- 1991-03-29 AU AU75478/91A patent/AU7547891A/en not_active Abandoned
- 1991-03-29 WO PCT/JP1991/000413 patent/WO1991015241A1/ja active IP Right Grant
- 1991-03-29 ES ES91906584T patent/ES2094809T3/es not_active Expired - Lifetime
- 1991-03-29 EP EP91906584A patent/EP0480054B1/de not_active Expired - Lifetime
- 1991-03-29 DE DE69122464T patent/DE69122464T2/de not_active Expired - Fee Related
- 1991-03-29 US US07/781,226 patent/US5240932A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0480054A4 (en) | 1992-08-05 |
WO1991015241A1 (en) | 1991-10-17 |
EP0480054B1 (de) | 1996-10-02 |
EP0480054A1 (de) | 1992-04-15 |
ES2094809T3 (es) | 1997-02-01 |
ATE143603T1 (de) | 1996-10-15 |
US5240932A (en) | 1993-08-31 |
DE69122464T2 (de) | 1997-02-20 |
AU7547891A (en) | 1991-10-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |