KR960700041A - 신규한 경피 흡수제제(Novel percutaneously absorbable preparation) - Google Patents

신규한 경피 흡수제제(Novel percutaneously absorbable preparation)

Info

Publication number
KR960700041A
KR960700041A KR1019950702967A KR19950702967A KR960700041A KR 960700041 A KR960700041 A KR 960700041A KR 1019950702967 A KR1019950702967 A KR 1019950702967A KR 19950702967 A KR19950702967 A KR 19950702967A KR 960700041 A KR960700041 A KR 960700041A
Authority
KR
South Korea
Prior art keywords
oil
pharmaceutical composition
aqueous ethanol
monoterpenes
external pharmaceutical
Prior art date
Application number
KR1019950702967A
Other languages
English (en)
Inventor
마사타카 가쓰마
히토시 가와이
가쓰미 사이토
나오코 스즈키
유타카 곤노
Original Assignee
오노다 마사요시
야마노우치세이야쿠 가부시키가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 오노다 마사요시, 야마노우치세이야쿠 가부시키가이샤 filed Critical 오노다 마사요시
Publication of KR960700041A publication Critical patent/KR960700041A/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

본 발명은 (a) 수성 에탄올에 완전히 또는 부분적으로 용해되는 생리학적 활성물질, (b) 수성 에탄올에 거의 용해되지 않는 모노테르펜 또는 수성 에탄올에 용해되는 모노테르펜과의 이의 혼합물. (c) 비이온성 계면활성제 및 (d) 수성 에탄올을 포함하는, 수중유 유액 형태의 외용 약제학적 조성물에 관한 것이다.
본 발명은 약물의 목적하는 피부침투를 가능하게 하고 피부를 자극하지 않는 고도로 안전한 경피 흡수 가능한 제제를 제공한다.

Description

신규한 경피 흡수제제(Novel percutaneously absorbable preparation)
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (9)

  1. (a) 수성 에탄올에 완전히 또는 부분적으로 용해되는 생리학적 활성물질, (b) 수성 에탄올에 거의 용해되지 않는 모노테르펜 또는 수성 에탄올에 용해되는 모노테르펜과의 이의 혼합물. (c) 비이온성 계면활성제 및 (d) 수성 에탄올을 포함하는, 수중유(O/W) 유액 형태의 외용 약제학적 조성물.
  2. 제1항에 있어서, 모노테르펜이 환식 모노테르펜을 함유하는 필수 오일 및 탄화수소에 속하는 환식 모노테르펜중에서 선택된 하나 이상의 화합물인 외용 약제학적 조성물.
  3. 제2항에 있어서, 환식 모노테르펜을 함유하는 필수 오일 또는 탄화수소에 속하는 환식 모노테르펜이 하나 이상의 리모넨, 오렌지유, 유칼립투스유, 투르펜틴유, 레몬유 및 스피어민트유 중에서 선택되고 성분들 총량을 기준으로 하여 1 내지 50중량%의 양으로 혼합되는 외용 약제학적 조성물.
  4. 제3항에 있어서, 환식 모노테르펜을 함유하는 필수 오일이 유칼립투스유인 외용 약제학적 조성물.
  5. 제1항에 있어서, 수성 에탄올에 거의 용해되지 않는 모노테르펜과 수성 에탄올에 용해되는 모노테르펜의 혼합물이 오렌지유와 멘타유, 오렌지유와 ℓ-멘톨, 오렌지유와 리나룰, 유칼립투스유와 멘타유 및 유칼립투스유와 ℓ-멘톨로 이루어진 조합중에서 선택되는 외용 약제학적 조성물.
  6. 제1항에 있어서, 비이온성 계면활성제가 폴리옥시에틸렌 경화 피마자유인 외용 약제학적 조성물.
  7. 제1항에 있어서, 에탄올이 성분들 총량을 기준으로 하여 5 내지 50중량%의 양으로 혼합되는 외용 약제학적 조성물.
  8. 제1항에 있어서, 수성 에탄올에 완전히 또는 부분적으로 용해되는 생리학적 활성물질이 이부세트론 하이드로클로라이드, 타무설로신 하이드로클로라이드 및 2-(3,4-디하이드로-2,2-디에밀-6-니트로-2H-1,4-벤즈옥사진-4-일) 피리딘 N-옥사이드 또는 이의 염중에서 선택되는 외용 약제학적 조성물.
  9. 제1항에 있어서, 첩제로서 사용되는 외용 약제학적 조성물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019950702967A 1993-01-21 1994-01-19 신규한 경피 흡수제제(Novel percutaneously absorbable preparation) KR960700041A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP93-026260 1993-01-21
JP2626093 1993-01-21
PCT/JP1994/000066 WO1994016682A1 (en) 1993-01-21 1994-01-19 Novel, percutaneously absorbable preparation

Publications (1)

Publication Number Publication Date
KR960700041A true KR960700041A (ko) 1996-01-19

Family

ID=12188302

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950702967A KR960700041A (ko) 1993-01-21 1994-01-19 신규한 경피 흡수제제(Novel percutaneously absorbable preparation)

Country Status (6)

Country Link
EP (1) EP0682942A4 (ko)
KR (1) KR960700041A (ko)
AU (1) AU5865694A (ko)
CA (1) CA2153882A1 (ko)
TW (1) TW283648B (ko)
WO (1) WO1994016682A1 (ko)

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JPH07109230A (ja) * 1993-10-07 1995-04-25 Kanebo Ltd 皮膚外用剤組成物
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KR19990026792A (ko) * 1997-09-26 1999-04-15 김윤 디클로페낙 디에틸암모늄염을 함유한 매트릭스형 패취제제
WO1999021533A2 (en) * 1997-10-24 1999-05-06 Neorx Corporation Delivery vehicles for bioactive agents and uses thereof
TW550080B (en) 1998-11-17 2003-09-01 Shionogi & Co Transdermic preparation comprising cerebral function activating agent
KR100390870B1 (ko) * 1999-02-09 2003-07-10 주식회사 삼양사 경피투여용 항구토제 조성물 및 이를 포함하는 제제
CN1209108C (zh) * 1999-02-09 2005-07-06 株式会社三养社 一种经皮肤传递的止吐剂成份和含相同成份的制剂
JP4873768B2 (ja) * 1999-08-19 2012-02-08 久光製薬株式会社 経皮吸収促進剤及び経皮吸収型製剤
DE19949202A1 (de) * 1999-10-13 2001-05-03 Lohmann Therapie Syst Lts Transdermales therapeutisches System zur Abgabe von Acetylsalicylsäure und/oder Salicylsäure
WO2002069967A1 (fr) * 2001-03-01 2002-09-12 Sankyo Company, Limited Compositions a absorption percutanee
GB2410897A (en) * 2004-02-13 2005-08-17 Reckitt Benckiser Method of deactivating allergens such as dust mites
GB2410899B (en) * 2004-02-13 2006-11-22 Reckitt Benckiser Method of deactivating dust mite allergens
JPWO2005094814A1 (ja) * 2004-03-31 2008-02-14 興和株式会社 外用剤
JP5096149B2 (ja) * 2005-08-22 2012-12-12 久光製薬株式会社 外用剤
GB0716605D0 (en) * 2007-08-24 2007-10-03 Univ Aston Skin antiseptics
BR112015007567B1 (pt) * 2012-10-26 2021-05-25 V. Mane Fils composição de microemulsão o/a e produto compreendendo a referida composição
JP6921493B2 (ja) * 2015-10-30 2021-08-18 小林製薬株式会社 水中油型乳化組成物
JP6847520B2 (ja) * 2017-02-03 2021-03-24 長谷川香料株式会社 テルペン系炭化水素香料化合物高含有の水中油型乳化香料組成物
CN118021691B (zh) * 2024-04-09 2024-07-02 广州天玺生物科技有限公司 一种深度补水的化妆品组合物及其制备方法

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US4702916A (en) * 1985-12-03 1987-10-27 Warner-Lambert Company Analgesic stick compositions
EP0289900A1 (en) * 1987-04-30 1988-11-09 Abbott Laboratories Topical antibacterial compositions
JP2651616B2 (ja) * 1989-02-03 1997-09-10 リンテック株式会社 経皮吸収製剤
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Also Published As

Publication number Publication date
EP0682942A4 (en) 1996-12-04
WO1994016682A1 (en) 1994-08-04
AU5865694A (en) 1994-08-15
CA2153882A1 (en) 1994-08-04
TW283648B (ko) 1996-08-21
EP0682942A1 (en) 1995-11-22

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