ATE78687T1 - Quaternaere derivate von noroxymorphon zur behandlung von uebelkeit und erbrechen. - Google Patents

Quaternaere derivate von noroxymorphon zur behandlung von uebelkeit und erbrechen.

Info

Publication number
ATE78687T1
ATE78687T1 AT87307999T AT87307999T ATE78687T1 AT E78687 T1 ATE78687 T1 AT E78687T1 AT 87307999 T AT87307999 T AT 87307999T AT 87307999 T AT87307999 T AT 87307999T AT E78687 T1 ATE78687 T1 AT E78687T1
Authority
AT
Austria
Prior art keywords
noroxymorphone
nausea
vomiting
treatment
quaternary derivatives
Prior art date
Application number
AT87307999T
Other languages
English (en)
Inventor
Leon I Goldberg
Original Assignee
Univ Chicago
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Chicago filed Critical Univ Chicago
Application granted granted Critical
Publication of ATE78687T1 publication Critical patent/ATE78687T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine

Landscapes

  • Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT87307999T 1987-09-10 1987-09-10 Quaternaere derivate von noroxymorphon zur behandlung von uebelkeit und erbrechen. ATE78687T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP87307999A EP0306575B1 (de) 1987-09-10 1987-09-10 Quaternäre Derivate von Noroxymorphon zur Behandlung von Übelkeit und Erbrechen

Publications (1)

Publication Number Publication Date
ATE78687T1 true ATE78687T1 (de) 1992-08-15

Family

ID=8198027

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87307999T ATE78687T1 (de) 1987-09-10 1987-09-10 Quaternaere derivate von noroxymorphon zur behandlung von uebelkeit und erbrechen.

Country Status (5)

Country Link
EP (1) EP0306575B1 (de)
AT (1) ATE78687T1 (de)
DE (1) DE3780819T2 (de)
ES (1) ES2051742T3 (de)
GR (1) GR3005834T3 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6274591B1 (en) * 1997-11-03 2001-08-14 Joseph F. Foss Use of methylnaltrexone and related compounds
BR0314488A (pt) * 2002-09-25 2005-08-02 Euro Celtique Sa Composto, composição farmacêutica e métodos de tratamento
DK2368553T3 (en) 2003-04-08 2015-02-09 Progenics Pharm Inc Pharmaceutical preparation comprising methylnaltrexone
US8518962B2 (en) 2005-03-07 2013-08-27 The University Of Chicago Use of opioid antagonists
US9662325B2 (en) 2005-03-07 2017-05-30 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
US8524731B2 (en) 2005-03-07 2013-09-03 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
CN101171010B (zh) 2005-03-07 2014-09-17 芝加哥大学 阿片样物质拮抗剂用于减少内皮细胞增殖和迁移的用途
AR057325A1 (es) 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
AR057035A1 (es) 2005-05-25 2007-11-14 Progenics Pharm Inc SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
EP2134718A2 (de) 2007-03-29 2009-12-23 Progenics Pharmaceuticals, Inc. Kristalline formen von (r)-n-methylnaltrexonbrom und ihre verwendung
PT2139890E (pt) 2007-03-29 2014-09-03 Wyeth Llc Antagonistas do receptor opióide periférico e respectivas utilizações
PL2137191T3 (pl) 2007-03-29 2016-12-30 Antagoniści obwodowego receptora opioidowego i ich zastosowania
AU2008349873B2 (en) 2008-02-06 2014-02-13 Progenics Pharmaceuticals, Inc. Preparation and use of (R),(R)-2,2'-bis-methylnaltrexone
AU2009225434B2 (en) 2008-03-21 2014-05-22 The University Of Chicago Treatment with opioid antagonists and mTOR inhibitors
CA2676881C (en) 2008-09-30 2017-04-25 Wyeth Peripheral opioid receptor antagonists and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1202148A (en) * 1968-03-06 1970-08-12 Sankyo Co Pharmaceutical compositions
US4176186A (en) * 1978-07-28 1979-11-27 Boehringer Ingelheim Gmbh Quaternary derivatives of noroxymorphone which relieve intestinal immobility
US4466968A (en) * 1980-11-24 1984-08-21 Dermall, Ltd. Method for prophylaxis or treatment of emesis and nausea
JPS59500418A (ja) * 1982-03-16 1984-03-15 ザ　ロツクフエラ−　ユニバ−シテイ 胃腸能動作用障害を回復する方法

Also Published As

Publication number Publication date
DE3780819T2 (de) 1993-01-14
EP0306575A1 (de) 1989-03-15
ES2051742T3 (es) 1994-07-01
GR3005834T3 (de) 1993-06-07
EP0306575B1 (de) 1992-07-29
DE3780819D1 (de) 1992-09-03

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time