DE69100588D1 - Verfahren zur Abtrennung und Reinigung von Monosialogangliosid durch Komplexierung mit Alpha-Cyclodextrin und Zwischenprodukte. - Google Patents

Verfahren zur Abtrennung und Reinigung von Monosialogangliosid durch Komplexierung mit Alpha-Cyclodextrin und Zwischenprodukte.

Info

Publication number
DE69100588D1
DE69100588D1 DE91111469T DE69100588T DE69100588D1 DE 69100588 D1 DE69100588 D1 DE 69100588D1 DE 91111469 T DE91111469 T DE 91111469T DE 69100588 T DE69100588 T DE 69100588T DE 69100588 D1 DE69100588 D1 DE 69100588D1
Authority
DE
Germany
Prior art keywords
cyclodextrin
monosialoganglioside
complexation
intermediates
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE91111469T
Other languages
English (en)
Other versions
DE69100588T2 (de
Inventor
Benito Casu
Ennio Lanzarotti
Giangiacomo Torri
Annamaria Naggi
Armando Cedro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Crinos Industria Farmacobiologica SpA
Original Assignee
Crinos Industria Farmacobiologica SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crinos Industria Farmacobiologica SpA filed Critical Crinos Industria Farmacobiologica SpA
Publication of DE69100588D1 publication Critical patent/DE69100588D1/de
Application granted granted Critical
Publication of DE69100588T2 publication Critical patent/DE69100588T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
DE91111469T 1990-07-13 1991-07-10 Verfahren zur Abtrennung und Reinigung von Monosialogangliosid durch Komplexierung mit Alpha-Cyclodextrin und Zwischenprodukte. Expired - Fee Related DE69100588T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT02094290A IT1243340B (it) 1990-07-13 1990-07-13 Metodo per isolare e purificare il monosialoganglioside ad elevato grado di purezza da una miscela lipidica che lo contiene e relativo composto intermedio

Publications (2)

Publication Number Publication Date
DE69100588D1 true DE69100588D1 (de) 1993-12-09
DE69100588T2 DE69100588T2 (de) 1994-03-31

Family

ID=11174397

Family Applications (1)

Application Number Title Priority Date Filing Date
DE91111469T Expired - Fee Related DE69100588T2 (de) 1990-07-13 1991-07-10 Verfahren zur Abtrennung und Reinigung von Monosialogangliosid durch Komplexierung mit Alpha-Cyclodextrin und Zwischenprodukte.

Country Status (9)

Country Link
US (1) US5108613A (de)
EP (1) EP0469352B1 (de)
JP (1) JPH04230398A (de)
AT (1) ATE96804T1 (de)
DE (1) DE69100588T2 (de)
DK (1) DK0469352T3 (de)
ES (1) ES2060257T3 (de)
IT (1) IT1243340B (de)
PT (1) PT98270A (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1747785A1 (de) * 2005-07-28 2007-01-31 Istituto Clinico Humanitas Cyclodextrin zur Blutentgiftung
US7943750B2 (en) * 2007-06-18 2011-05-17 Laboratoire Medidom S.A. Process for obtaining pure monosialoganglioside GM1 for medical use
CN103087120B (zh) * 2013-02-26 2015-12-02 北京四环制药有限公司 单唾液酸四己糖神经节苷脂的制备方法及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS615024A (ja) * 1984-06-18 1986-01-10 Takeda Chem Ind Ltd 生薬製剤の製造法
US4868291A (en) * 1987-08-20 1989-09-19 Bristol-Myers Company 4'-deshydroxyepipodophyllotoxin glucosides: synthesis and use
IT1223408B (it) * 1987-12-09 1990-09-19 Crinos Industria Farmaco Procedimento per la preparazione di monosialoganglioside
CH677494A5 (de) * 1988-10-28 1991-05-31 Nestle Sa

Also Published As

Publication number Publication date
JPH04230398A (ja) 1992-08-19
ES2060257T3 (es) 1994-11-16
DE69100588T2 (de) 1994-03-31
PT98270A (pt) 1992-05-29
EP0469352A1 (de) 1992-02-05
US5108613A (en) 1992-04-28
IT9020942A1 (it) 1992-01-13
EP0469352B1 (de) 1993-11-03
DK0469352T3 (da) 1994-01-03
IT9020942A0 (it) 1990-07-13
ATE96804T1 (de) 1993-11-15
IT1243340B (it) 1994-06-10

Similar Documents

Publication Publication Date Title
DE3852901D1 (de) Verfahren zur Herstellung eines laminierten Produktes.
DE69009816D1 (de) Verfahren zur Herstellung von Siloxanharzen.
DE3889393D1 (de) Verfahren zur Herstellung von 2,2,6,6-Tetramethyl-4-piperidylaminen.
DE3889290D1 (de) Verfahren zur Herstellung von Polyketonen.
DE69110102D1 (de) Verfahren zur Herstellung von Eiscreme.
DE68913817D1 (de) Verfahren zur Herstellung einer dem Kefir ähnlichen Sauermilch.
DE69005606D1 (de) Verfahren zur Herstellung von Phenol.
DE69122936D1 (de) Verfahren zur Herstellung von Sialsäure
DE3884367D1 (de) Verfahren zur Herstellung von Feinstdraht.
DE3864997D1 (de) Verfahren zur herstellung von sauermilchprodukten.
DE69016840D1 (de) Verfahren zur Herstellung eines lateralen Bipolartransistors.
DE69020172D1 (de) Verfahren zur Herstellung von epsilon-Caprolactam.
DE69100588D1 (de) Verfahren zur Abtrennung und Reinigung von Monosialogangliosid durch Komplexierung mit Alpha-Cyclodextrin und Zwischenprodukte.
DE69009682D1 (de) Verfahren zur Herstellung von Cyclohexanolderivaten.
DE3851588D1 (de) Verfahren zur Herstellung von Chinoloncarbonsäuren.
DE68918050D1 (de) Verfahren zur Herstellung von Windschutzscheiben.
DE68923635D1 (de) Verfahren zur Herstellung von fester Lactulose.
DE69313932D1 (de) Verfahren zur Herstellung eines Sauermilchproduktes
DE69017510D1 (de) Verfahren zur Herstellung von Nylonstapelfasern.
ATE70064T1 (de) Verfahren zur herstellung von penemen.
DE59204049D1 (de) Verfahren zur Herstellung von Hydroxylammoniumsalzen.
DE3850177D1 (de) Verfahren zur Herstellung von tertiären Alkyldimethylhalosilanen.
DE3788908D1 (de) Verfahren zur Herstellung von Zuckern aus Stärke.
DE3889068D1 (de) Verfahren zur Herstellung von Polyketonen.
DE69101601D1 (de) Verfahren zur Herstellung eines Milchprotein-Isolates.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee