IT1243340B - Metodo per isolare e purificare il monosialoganglioside ad elevato grado di purezza da una miscela lipidica che lo contiene e relativo composto intermedio - Google Patents
Metodo per isolare e purificare il monosialoganglioside ad elevato grado di purezza da una miscela lipidica che lo contiene e relativo composto intermedioInfo
- Publication number
- IT1243340B IT1243340B IT02094290A IT2094290A IT1243340B IT 1243340 B IT1243340 B IT 1243340B IT 02094290 A IT02094290 A IT 02094290A IT 2094290 A IT2094290 A IT 2094290A IT 1243340 B IT1243340 B IT 1243340B
- Authority
- IT
- Italy
- Prior art keywords
- purifying
- isolating
- mixture containing
- intermediate compound
- lipid mixture
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
- C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Saccharide Compounds (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT02094290A IT1243340B (it) | 1990-07-13 | 1990-07-13 | Metodo per isolare e purificare il monosialoganglioside ad elevato grado di purezza da una miscela lipidica che lo contiene e relativo composto intermedio |
DK91111469.2T DK0469352T3 (da) | 1990-07-13 | 1991-07-10 | Fremgangsmåde til isolering og oprensning af monosialgangliosid fra en udgangslipidblanding ved kompleksering med alfa-cyclodextrin og beslægtet mellemforbindelse |
AT91111469T ATE96804T1 (de) | 1990-07-13 | 1991-07-10 | Verfahren zur abtrennung und reinigung von monosialogangliosid durch komplexierung mit alpha-cyclodextrin und zwischenprodukte. |
PT98270A PT98270A (pt) | 1990-07-13 | 1991-07-10 | Metodo para o isolamento e purificacao de monosialogangliosido a partir de uma mistura lipidica de partida por complexacao com alfa-ciclodextrina e processo para a preparacao de um composto intermediario relacionado |
DE91111469T DE69100588T2 (de) | 1990-07-13 | 1991-07-10 | Verfahren zur Abtrennung und Reinigung von Monosialogangliosid durch Komplexierung mit Alpha-Cyclodextrin und Zwischenprodukte. |
ES91111469T ES2060257T3 (es) | 1990-07-13 | 1991-07-10 | Procedimiento de aislamiento y purificacion de monosialogangliosido a partir de una mezcla lipidica de partida mediante complejificacion con alfa-ciclodextrina y compuesto intermedio relacionado. |
EP91111469A EP0469352B1 (en) | 1990-07-13 | 1991-07-10 | Process for the isolation and purification of monosialoganglioside from a starting lipidic mixture by complexation with alpha-cyclodextrin and related intermediate compound |
JP3174194A JPH04230398A (ja) | 1990-07-13 | 1991-07-15 | α−サイクロデキストリンとの複合化による出発原料の脂質混合物からのモノシアロガングリオシドの単離精製方法および関連の中間体化合物 |
US07/729,728 US5108613A (en) | 1990-07-13 | 1991-07-15 | Process for the isolation and purification of monosialoganglioside from a starting lipidic mixture by complexation with alfa-cyclodextrin and related intermediate compound |
US07/834,454 US5152998A (en) | 1990-07-13 | 1992-02-12 | Process for the isolation and purification of monosialoganglioside from a starting lipidic mixture by complexation with alpha-cyclodextrin and related intermediate compound |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT02094290A IT1243340B (it) | 1990-07-13 | 1990-07-13 | Metodo per isolare e purificare il monosialoganglioside ad elevato grado di purezza da una miscela lipidica che lo contiene e relativo composto intermedio |
Publications (3)
Publication Number | Publication Date |
---|---|
IT9020942A0 IT9020942A0 (it) | 1990-07-13 |
IT9020942A1 IT9020942A1 (it) | 1992-01-13 |
IT1243340B true IT1243340B (it) | 1994-06-10 |
Family
ID=11174397
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT02094290A IT1243340B (it) | 1990-07-13 | 1990-07-13 | Metodo per isolare e purificare il monosialoganglioside ad elevato grado di purezza da una miscela lipidica che lo contiene e relativo composto intermedio |
Country Status (9)
Country | Link |
---|---|
US (1) | US5108613A (it) |
EP (1) | EP0469352B1 (it) |
JP (1) | JPH04230398A (it) |
AT (1) | ATE96804T1 (it) |
DE (1) | DE69100588T2 (it) |
DK (1) | DK0469352T3 (it) |
ES (1) | ES2060257T3 (it) |
IT (1) | IT1243340B (it) |
PT (1) | PT98270A (it) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1747785A1 (en) * | 2005-07-28 | 2007-01-31 | Istituto Clinico Humanitas | Cyclodextrins for blood detoxification |
US7943750B2 (en) * | 2007-06-18 | 2011-05-17 | Laboratoire Medidom S.A. | Process for obtaining pure monosialoganglioside GM1 for medical use |
CN103087120B (zh) * | 2013-02-26 | 2015-12-02 | 北京四环制药有限公司 | 单唾液酸四己糖神经节苷脂的制备方法及其应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS615024A (ja) * | 1984-06-18 | 1986-01-10 | Takeda Chem Ind Ltd | 生薬製剤の製造法 |
US4868291A (en) * | 1987-08-20 | 1989-09-19 | Bristol-Myers Company | 4'-deshydroxyepipodophyllotoxin glucosides: synthesis and use |
IT1223408B (it) * | 1987-12-09 | 1990-09-19 | Crinos Industria Farmaco | Procedimento per la preparazione di monosialoganglioside |
CH677494A5 (it) * | 1988-10-28 | 1991-05-31 | Nestle Sa |
-
1990
- 1990-07-13 IT IT02094290A patent/IT1243340B/it active IP Right Grant
-
1991
- 1991-07-10 PT PT98270A patent/PT98270A/pt not_active Application Discontinuation
- 1991-07-10 ES ES91111469T patent/ES2060257T3/es not_active Expired - Lifetime
- 1991-07-10 AT AT91111469T patent/ATE96804T1/de not_active IP Right Cessation
- 1991-07-10 DK DK91111469.2T patent/DK0469352T3/da active
- 1991-07-10 DE DE91111469T patent/DE69100588T2/de not_active Expired - Fee Related
- 1991-07-10 EP EP91111469A patent/EP0469352B1/en not_active Expired - Lifetime
- 1991-07-15 JP JP3174194A patent/JPH04230398A/ja active Pending
- 1991-07-15 US US07/729,728 patent/US5108613A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0469352A1 (en) | 1992-02-05 |
DE69100588D1 (de) | 1993-12-09 |
EP0469352B1 (en) | 1993-11-03 |
PT98270A (pt) | 1992-05-29 |
ES2060257T3 (es) | 1994-11-16 |
DK0469352T3 (da) | 1994-01-03 |
JPH04230398A (ja) | 1992-08-19 |
US5108613A (en) | 1992-04-28 |
ATE96804T1 (de) | 1993-11-15 |
IT9020942A0 (it) | 1990-07-13 |
DE69100588T2 (de) | 1994-03-31 |
IT9020942A1 (it) | 1992-01-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19940727 |