IT8622852A0 - Metodo per la produzione diprodotti cristallini puri. - Google Patents

Metodo per la produzione diprodotti cristallini puri.

Info

Publication number
IT8622852A0
IT8622852A0 IT8622852A IT2285286A IT8622852A0 IT 8622852 A0 IT8622852 A0 IT 8622852A0 IT 8622852 A IT8622852 A IT 8622852A IT 2285286 A IT2285286 A IT 2285286A IT 8622852 A0 IT8622852 A0 IT 8622852A0
Authority
IT
Italy
Prior art keywords
production
pure crystalline
crystalline products
products
pure
Prior art date
Application number
IT8622852A
Other languages
English (en)
Other versions
IT1214587B (it
Inventor
Giovanni Bonfanti
Original Assignee
Giovanni Bonfanti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Giovanni Bonfanti filed Critical Giovanni Bonfanti
Priority to IT8622852A priority Critical patent/IT1214587B/it
Publication of IT8622852A0 publication Critical patent/IT8622852A0/it
Priority to EP87116501A priority patent/EP0273156A3/en
Priority to US07/118,888 priority patent/US4912211A/en
Priority to JP62297281A priority patent/JPS63166839A/ja
Priority to KR870014661A priority patent/KR880007542A/ko
Application granted granted Critical
Publication of IT1214587B publication Critical patent/IT1214587B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B63/00—Purification; Separation; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/04—Preparation
    • C07D499/18—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
IT8622852A 1986-12-23 1986-12-23 Metodo per la produzione diprodotti cristallini puri. IT1214587B (it)

Priority Applications (5)

Application Number Priority Date Filing Date Title
IT8622852A IT1214587B (it) 1986-12-23 1986-12-23 Metodo per la produzione diprodotti cristallini puri.
EP87116501A EP0273156A3 (en) 1986-12-23 1987-11-09 Method for producing pure crystalline products
US07/118,888 US4912211A (en) 1986-12-23 1987-11-10 Method for producing pure crystalline antibiotic products
JP62297281A JPS63166839A (ja) 1986-12-23 1987-11-25 純粋な結晶製品の製造法
KR870014661A KR880007542A (ko) 1986-12-23 1987-12-22 순수 결정성 생성물의 제조방법

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8622852A IT1214587B (it) 1986-12-23 1986-12-23 Metodo per la produzione diprodotti cristallini puri.

Publications (2)

Publication Number Publication Date
IT8622852A0 true IT8622852A0 (it) 1986-12-23
IT1214587B IT1214587B (it) 1990-01-18

Family

ID=11201177

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8622852A IT1214587B (it) 1986-12-23 1986-12-23 Metodo per la produzione diprodotti cristallini puri.

Country Status (5)

Country Link
US (1) US4912211A (it)
EP (1) EP0273156A3 (it)
JP (1) JPS63166839A (it)
KR (1) KR880007542A (it)
IT (1) IT1214587B (it)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5142042A (en) * 1989-01-23 1992-08-25 Purzer Pharmaceutical Co., Ltd. Process for preparing well crystallized alkali metal salts of 3, 7-substituted 7-aminocephalosporanic acid derivatives
DE3911322A1 (de) * 1989-04-07 1990-10-11 Hoechst Ag Verfahren zur herstellung von cefodizim-dinatrium
CN1055090C (zh) * 1993-03-12 2000-08-02 法玛西雅厄普约翰美国公司 结晶性头孢噻夫游离酸
KR0180798B1 (ko) * 1993-11-06 1999-03-20 고바야시 요시오 결정성 페니실린 유도체, 그의 제법 및 용도
GB9423459D0 (en) * 1994-11-21 1995-01-11 Biochemie Gmbh Silylation process
AT402928B (de) * 1994-12-23 1997-09-25 Biochemie Gmbh Neues verfahren zur herstellung von cefotaxim
ES2134128B1 (es) * 1997-01-17 2000-05-01 Antibioticos Sa Un procedimiento de reduccion de los niveles residuales de disolventes, presentes en las composiciones farmaceuticas, en particular en los antibioticos y antibioticos obtenidos segun el mismo.
AU728627B2 (en) * 1997-08-25 2001-01-11 Otsuka Chemical Co. Ltd. Cephalosporin crystals and process for their preparation
AR014939A1 (es) 1997-12-22 2001-04-11 Astrazeneca Ab Proceso para purificar una solucion de un ester profarmaco de ampicilina
AT411996B (de) * 2000-09-11 2004-08-26 Sandoz Ag Verfahren zur herstellung von cefuroxim in der form seines n-butylammoniumsalzes
US20040092735A1 (en) * 2002-11-08 2004-05-13 Orchid Chemicals & Pharmaceuticals Limited Process for the preparation of cefuroxime sodium
US7842791B2 (en) * 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
RU2457211C1 (ru) * 2011-01-12 2012-07-27 Общество С Ограниченной Ответственностью Нпф "Файн Кемикалс" Способ получения натриевой соли 6-[3-(2-хлор-6-фторфенил)-5-метилизоксазол-4-карбамино]-пенициллановой кислоты
CN102285998B (zh) * 2011-06-17 2013-12-18 桂林理工大学 氟氯西林钠无定形和三种多晶型物的制备方法
CN103717607A (zh) * 2012-09-12 2014-04-09 海南卫康制药(潜山)有限公司 头孢呋辛钠新晶型化合物及其组合物粉针
CN102964356B (zh) * 2012-12-25 2015-06-17 菏泽睿智科技开发有限公司 一种氟氯西林钠的合成方法
CN105153196B (zh) * 2015-09-15 2018-01-16 桂林南药股份有限公司 一种氟氯西林钠晶型、制备方法及应用
CN108659007B (zh) * 2018-07-23 2020-08-25 华北制药集团先泰药业有限公司 一种双氯西林钠柱形晶体的制备方法
CN111548357B (zh) * 2020-04-16 2021-07-13 华北制药河北华民药业有限责任公司 一种高纯度头孢唑林钠及其药物制剂的制备方法
CN113788843B (zh) * 2021-09-30 2022-07-19 海南海灵化学制药有限公司 一种注射用头孢呋辛钠的制备工艺

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2128207A1 (en) * 1971-06-07 1972-12-14 Purificn of org cpds - by meta-dissoln,esp for substd 2-mercapto-benzthiazoles,nitrones and organometallic cpds
US4061853A (en) * 1975-12-09 1977-12-06 Ciba-Geigy Corporation Virtually solvent-free crystal form of the sodium salt of Cephacetril

Also Published As

Publication number Publication date
KR880007542A (ko) 1988-08-27
JPS63166839A (ja) 1988-07-11
EP0273156A2 (en) 1988-07-06
US4912211A (en) 1990-03-27
EP0273156A3 (en) 1990-04-04
IT1214587B (it) 1990-01-18

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