DE69028479T2 - Genetische Manipulationen mit von RNA-Viren abgeleiteten Sequenzen enthaltendem rekombinantem DNA - Google Patents

Genetische Manipulationen mit von RNA-Viren abgeleiteten Sequenzen enthaltendem rekombinantem DNA

Info

Publication number
DE69028479T2
DE69028479T2 DE69028479T DE69028479T DE69028479T2 DE 69028479 T2 DE69028479 T2 DE 69028479T2 DE 69028479 T DE69028479 T DE 69028479T DE 69028479 T DE69028479 T DE 69028479T DE 69028479 T2 DE69028479 T2 DE 69028479T2
Authority
DE
Germany
Prior art keywords
rna
viral
virus
plants
replication
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69028479T
Other languages
German (de)
English (en)
Other versions
DE69028479D1 (de
Inventor
Paul Ameloot
Lafonteyne Jean De
Walter Fiers
Haute Eddie Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Clovis Matton NV
Aveve NV
Solvay SA
Original Assignee
Clovis Matton NV
Aveve NV
Solvay SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from NL8902452A external-priority patent/NL8902452A/nl
Application filed by Clovis Matton NV, Aveve NV, Solvay SA filed Critical Clovis Matton NV
Publication of DE69028479D1 publication Critical patent/DE69028479D1/de
Application granted granted Critical
Publication of DE69028479T2 publication Critical patent/DE69028479T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241Nucleotidyltransferases (2.7.7)
    • C12N9/127RNA-directed RNA polymerase (2.7.7.48), i.e. RNA replicase
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/48Nerve growth factor [NGF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8202Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by biological means, e.g. cell mediated or natural vector
    • C12N15/8203Virus mediated transformation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8283Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for virus resistance
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/38011Tombusviridae
    • C12N2770/38022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DE69028479T 1989-10-03 1990-10-03 Genetische Manipulationen mit von RNA-Viren abgeleiteten Sequenzen enthaltendem rekombinantem DNA Expired - Fee Related DE69028479T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8902452A NL8902452A (nl) 1989-10-03 1989-10-03 Genetische manipulaties met recombinant dna, dat rna-virus-specifieke sequenties omvat.
NL9001711A NL9001711A (nl) 1989-10-03 1990-07-27 Genetische manipulaties met recombinant dna, dat van rna virus afgeleide sequenties omvat.

Publications (2)

Publication Number Publication Date
DE69028479D1 DE69028479D1 (de) 1996-10-17
DE69028479T2 true DE69028479T2 (de) 1997-04-03

Family

ID=26646589

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69028479T Expired - Fee Related DE69028479T2 (de) 1989-10-03 1990-10-03 Genetische Manipulationen mit von RNA-Viren abgeleiteten Sequenzen enthaltendem rekombinantem DNA

Country Status (12)

Country Link
US (1) US6197542B1 (https=)
EP (1) EP0425004B1 (https=)
JP (1) JPH03280883A (https=)
AT (1) ATE142700T1 (https=)
CA (2) CA2396794A1 (https=)
DE (1) DE69028479T2 (https=)
DK (1) DK0425004T3 (https=)
ES (1) ES2094744T3 (https=)
GR (1) GR3021950T3 (https=)
IE (1) IE76133B1 (https=)
NL (1) NL9001711A (https=)
PT (1) PT95494B (https=)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7033835B1 (en) 1988-02-26 2006-04-25 Large Scale Biology Corporation Production of peptides in plants as viral coat protein fusions
US5922602A (en) * 1988-02-26 1999-07-13 Biosource Technologies, Inc. Cytoplasmic inhibition of gene expression
US5977438A (en) * 1988-02-26 1999-11-02 Biosource Technologies, Inc. Production of peptides in plants as viral coat protein fusions
US6660500B2 (en) 1988-02-26 2003-12-09 Large Scale Biology Corporation Production of peptides in plants as viral coat protein fusions
US6054566A (en) 1988-02-26 2000-04-25 Biosource Technologies, Inc. Recombinant animal viral nucleic acids
JPH07503361A (ja) * 1991-08-01 1995-04-13 バイオソース テクノロジーズ インコーポレイティド 組み換え植物ウィルス核酸
ATE276373T1 (de) * 1991-10-04 2004-10-15 Univ North Carolina State Pathogenresistente transgene pflanzen
CA2130454C (en) * 1992-02-19 2008-04-08 William G. Dougherty Production of viral resistant plants via introduction of untranslatable plus sense viral rna
EP0641384A4 (en) * 1992-05-14 1995-07-12 Ribozyme Pharm Inc INDUCIBLE CYTOTOXIC mRNAs CONTAINING VIRUS-RESISTANT PLANTS.
EP0677113B1 (en) * 1992-12-30 2003-03-12 Biosource Genetics Corporation Viral amplification of recombinant messenger rna in transgenic plants
IL108241A (en) * 1992-12-30 2000-08-13 Biosource Genetics Corp Plant expression system comprising a defective tobamovirus replicon integrated into the plant chromosome and a helper virus
US6008436A (en) * 1993-01-21 1999-12-28 North Carolina State University Nematode-resistant transgenic plants
US5650303A (en) * 1993-02-26 1997-07-22 Calgene, Inc. Geminivirus-based gene expression system
DK0686197T3 (da) * 1993-02-26 2000-09-04 Calgene Llc Geminivirusbaseret genekspressionssystem
US5981236A (en) * 1993-02-26 1999-11-09 Calgene Inc Geminivirus-based gene expression system
DE4315109A1 (de) * 1993-05-06 1994-11-10 Inst Pflanzengenetik & Kultur Verfahren und Vektorkonstrukt zur Expressionssteigerung von Transgenen
GB9311593D0 (en) * 1993-06-04 1993-07-21 Sandoz Ltd Improvements in or relating to organic compounds
GB9401780D0 (en) * 1994-01-31 1994-03-23 Nickerson Biocem Ltd Modified plants
AU3409295A (en) * 1994-08-18 1996-03-14 Ariad Gene Therapeutics, Inc. Regulatable elimination of gene expression, gene product function and engineered host cells
IT1283631B1 (it) * 1996-05-09 1998-04-23 Metapontum Agrobios Srl Metodo per la preparazione di piante transgeniche resistenti ad in- fezioni virali e piante cosi' ottenute
GB9615349D0 (en) * 1996-07-22 1996-09-04 Zeneca Ltd Virus resistance in plants
GB9703146D0 (en) * 1997-02-14 1997-04-02 Innes John Centre Innov Ltd Methods and means for gene silencing in transgenic plants
GB9720148D0 (en) * 1997-09-22 1997-11-26 Innes John Centre Innov Ltd Gene silencing materials and methods
AU731330B2 (en) * 1997-10-24 2001-03-29 E.I. Du Pont De Nemours And Company Binary viral expression system in plants
US6077992A (en) * 1997-10-24 2000-06-20 E. I. Du Pont De Nemours And Company Binary viral expression system in plants
US6632980B1 (en) 1997-10-24 2003-10-14 E. I. Du Pont De Nemours And Company Binary viral expression system in plants
US6759243B2 (en) 1998-01-20 2004-07-06 Board Of Trustees Of The University Of Illinois High affinity TCR proteins and methods
HUP0104697A3 (en) * 1998-09-23 2003-12-29 Du Pont Binary viral expression system in plants
US7220893B1 (en) 1999-05-19 2007-05-22 Cornell Research Foundation, Inc. Plasmids and methods for construction of non-redundant, indexed, saturation, gene-disruption plant and animal libraries
US7696406B2 (en) * 2003-07-03 2010-04-13 Board Of Trustees Operating Michigan State University Expression of a recombinant transgene
CN110144338A (zh) * 2019-05-29 2019-08-20 通用生物系统(安徽)有限公司 一种以rna为模板的rna聚合酶制备方法及该聚合酶的应用
US12234701B2 (en) 2022-09-12 2025-02-25 Saudi Arabian Oil Company Tubing hangers and related methods of isolating a tubing
US12188328B2 (en) 2023-05-15 2025-01-07 Saudi Arabian Oil Company Wellbore back pressure valve with pressure gauge
US12442257B2 (en) 2023-05-23 2025-10-14 Saudi Arabian Oil Company Completing and working over a wellbore

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2624342B1 (fr) * 1987-12-14 1991-11-08 Agronomique Inst Nat Rech Procede d'obtention de plantes transgeniques, vecteur d'integration utilise et plantes obtenues
AU638411B2 (en) * 1988-02-26 1993-07-01 Large Scale Biology Corporation Non-nuclear chromosomal transformation
CN1033645A (zh) * 1988-10-22 1989-07-05 中国科学院上海植物生理研究所 控制植物病毒病的基因工程方法

Also Published As

Publication number Publication date
ATE142700T1 (de) 1996-09-15
JPH03280883A (ja) 1991-12-11
DK0425004T3 (https=) 1997-03-10
EP0425004B1 (en) 1996-09-11
ES2094744T3 (es) 1997-02-01
GR3021950T3 (en) 1997-03-31
IE76133B1 (en) 1997-10-08
US6197542B1 (en) 2001-03-06
CA2396794A1 (en) 1991-04-04
DE69028479D1 (de) 1996-10-17
CA2026703C (en) 2002-11-26
NL9001711A (nl) 1991-05-01
IE903541A1 (en) 1991-04-10
PT95494B (pt) 1997-11-28
PT95494A (pt) 1991-09-13
EP0425004A3 (en) 1991-08-07
EP0425004A2 (en) 1991-05-02
CA2026703A1 (en) 1991-04-04

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