DE69018352T2 - N-hydroxy-dibenz[b,e]oxepin-alkylamine und -alkanoische Säureamide, verwandte heterocyclische Analoge, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von Medikamenten. - Google Patents

N-hydroxy-dibenz[b,e]oxepin-alkylamine und -alkanoische Säureamide, verwandte heterocyclische Analoge, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von Medikamenten.

Info

Publication number
DE69018352T2
DE69018352T2 DE69018352T DE69018352T DE69018352T2 DE 69018352 T2 DE69018352 T2 DE 69018352T2 DE 69018352 T DE69018352 T DE 69018352T DE 69018352 T DE69018352 T DE 69018352T DE 69018352 T2 DE69018352 T2 DE 69018352T2
Authority
DE
Germany
Prior art keywords
dibenz
hydroxy
acid amides
oxepin
alkylamines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69018352T
Other languages
English (en)
Other versions
DE69018352D1 (de
Inventor
Richard C Allen
Grover Cleveland Helsley
Russell Richard Lee Hamer
Brian S Freed
John I White
Lawrence Leo Martin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Roussel Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharmaceuticals Inc filed Critical Hoechst Roussel Pharmaceuticals Inc
Application granted granted Critical
Publication of DE69018352D1 publication Critical patent/DE69018352D1/de
Publication of DE69018352T2 publication Critical patent/DE69018352T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/12—[b,e]-condensed

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Epoxy Compounds (AREA)
DE69018352T 1989-08-25 1990-08-22 N-hydroxy-dibenz[b,e]oxepin-alkylamine und -alkanoische Säureamide, verwandte heterocyclische Analoge, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von Medikamenten. Expired - Fee Related DE69018352T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39860789A 1989-08-25 1989-08-25

Publications (2)

Publication Number Publication Date
DE69018352D1 DE69018352D1 (de) 1995-05-11
DE69018352T2 true DE69018352T2 (de) 1995-10-26

Family

ID=23576030

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69018352T Expired - Fee Related DE69018352T2 (de) 1989-08-25 1990-08-22 N-hydroxy-dibenz[b,e]oxepin-alkylamine und -alkanoische Säureamide, verwandte heterocyclische Analoge, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von Medikamenten.

Country Status (17)

Country Link
EP (1) EP0419844B1 (de)
JP (1) JPH0778060B2 (de)
KR (1) KR0156537B1 (de)
AT (1) ATE120741T1 (de)
AU (2) AU636644B2 (de)
CA (1) CA2023951C (de)
DE (1) DE69018352T2 (de)
DK (1) DK0419844T3 (de)
ES (1) ES2070962T3 (de)
FI (1) FI90539C (de)
IE (1) IE66683B1 (de)
IL (1) IL95477A (de)
NO (1) NO174295C (de)
NZ (1) NZ235025A (de)
PT (1) PT95100B (de)
TW (1) TW209861B (de)
ZA (1) ZA906747B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR920003928B1 (ko) * 1988-09-20 1992-05-18 히사미쯔세이야꾸 가부시기가이샤 신규의 디벤즈[b,e]옥세핀유도체
KR100280865B1 (ko) * 1998-04-03 2001-02-01 이태근 닭및지렁이의순환적활용에의한음식물쓰레기의소멸처리방법
KR19990046663A (ko) * 1999-04-12 1999-07-05 차만수 어즙흡착발효사료제조방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4585788A (en) * 1973-09-06 1986-04-29 American Hoechst Corporation 6,11-dihydrodibenz[b,e]oxepin-acetic acids and derivatives
US4496580A (en) * 1981-07-23 1985-01-29 Hoechst-Roussel Pharmaceuticals Inc. Oxothienobenzoxepins
JPS5821679A (ja) * 1981-07-31 1983-02-08 メルク　エンド　カムパニー　インコーポレーテツド ジベンツ〔ｂ，ｅ〕オキセピン化合物
US4477465A (en) * 1983-03-10 1984-10-16 Hoechst-Roussel Pharmaceuticals Inc. Substituted 4,10-dihydro-10-oxothieno benzoxepins
JPS6310784A (ja) * 1986-03-03 1988-01-18 Kyowa Hakko Kogyo Co Ltd 抗アレルギー剤
US4981865A (en) 1989-05-26 1991-01-01 Warner-Lambert Co. N-hydroxyamide, N-hydroxythioamide, hydroxyurea, and N-hydroxythiourea derivatives of selected nsaids as antiinflammatory agents

Also Published As

Publication number Publication date
IE66683B1 (en) 1996-01-24
NO174295C (no) 1994-04-13
FI904184A0 (fi) 1990-08-23
EP0419844A1 (de) 1991-04-03
IL95477A (en) 1998-03-10
AU658264B2 (en) 1995-04-06
IL95477A0 (en) 1991-06-30
IE903093A1 (en) 1991-02-27
AU3375893A (en) 1993-07-15
KR910004593A (ko) 1991-03-29
EP0419844B1 (de) 1995-04-05
PT95100A (pt) 1991-04-18
NO903727L (no) 1991-02-26
JPH0778060B2 (ja) 1995-08-23
TW209861B (de) 1993-07-21
AU6131890A (en) 1991-02-28
CA2023951A1 (en) 1991-02-26
FI90539B (fi) 1993-11-15
PT95100B (pt) 1997-05-28
FI90539C (fi) 1994-02-25
NZ235025A (en) 1993-02-25
KR0156537B1 (ko) 1999-10-01
DK0419844T3 (da) 1995-08-28
DE69018352D1 (de) 1995-05-11
ZA906747B (en) 1991-06-26
NO903727D0 (no) 1990-08-24
ES2070962T3 (es) 1995-06-16
CA2023951C (en) 2001-04-03
ATE120741T1 (de) 1995-04-15
NO174295B (no) 1994-01-03
AU636644B2 (en) 1993-05-06
JPH0390077A (ja) 1991-04-16

Similar Documents

Publication Publication Date Title
AU5752194A (en) Benzimidazole compounds, their use and preparation
AU4257889A (en) Sulphonamido-phenylalkanoic acid derivatives having thromboxane A2 antagonist activity
HU9600834D0 (en) Quinazoline derivatives
DE69601345D1 (de) Propiophenon-Derivate und Verfahren zur ihrer Herstellung
AU626740B2 (en) Aminocarbonylcarbamates related to physostigmine, a process for their preparation and their use as medicaments
NO850216L (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive substituerte 5,11-dihydro-6-dibenz(b,e)-azepin-6-on-derivater
PT79457A (en) 11-substituted 5h,11h-pyrrolo<2,1-c><1,4>benzoxazepine a process for their preparation and their use as medicaments
ATE44280T1 (de) Trizyklische verbindungen, verfahren zur herstellung derselben, pharmazeutische praeparate und behandlungsmethode.
PT870761E (pt) Derivados de tiocolchicina com actividades anti-inflamatoria e relaxante muscular
DE69018352T2 (de) N-hydroxy-dibenz[b,e]oxepin-alkylamine und -alkanoische Säureamide, verwandte heterocyclische Analoge, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von Medikamenten.
IT1211792B (it) O-alcanoil derivati dell'acido 3ammino-2-idrossipropansolfonico adattivita'anticonvulsivante e loro composizioni farmaceutiche per il trattamento terapeutico dell'epilessia
ATE111899T1 (de) 1,2,3,4-tetrahydro-1,9-acridindiamine, ein verfahren zu ihrer herstellung und ihre verwendung als medikamente.
ATE117307T1 (de) Serinderivate, verfahren zu ihrer herstellung und ihre verwendung in der humantherapie.
DE69014261D1 (de) N-Azabicyclo[3.3.0]octanamide von aromatischen Säuren.
DE69127572D1 (de) Verwendung von Benzodiazepinverbindungen zur Herstellung eines Arzneimittels gegen mit excitatorischen Aminosäuren verbundene Zentralnervensystem-Störungen
DE69229017T2 (de) Glyceraldehyd-3-pentanid und Verfahren zu ihrer Herstellung
DE69412794T2 (de) 2'-desoxy-5-fluoruridin, pharmazeutisch anwendbare salze davon, verfahren zu ihrer herstellung und antitumormedikament
EP0301466A3 (en) Uricosuric composition

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee