DE69003061T2 - Protein enthaltende wässerige Lösungen. - Google Patents

Protein enthaltende wässerige Lösungen.

Info

Publication number
DE69003061T2
DE69003061T2 DE90310287T DE69003061T DE69003061T2 DE 69003061 T2 DE69003061 T2 DE 69003061T2 DE 90310287 T DE90310287 T DE 90310287T DE 69003061 T DE69003061 T DE 69003061T DE 69003061 T2 DE69003061 T2 DE 69003061T2
Authority
DE
Germany
Prior art keywords
protein
aqueous solutions
solutions containing
containing protein
aqueous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE90310287T
Other languages
English (en)
Other versions
DE69003061D1 (de
Inventor
Yukio Shimazaki
Nobuhiro Kawashima
Miki Yoshioka
Yasuhito Tanaka
Ryo Tanaka
Kiyoshi Sakai
Hisahiro Ishiwari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Chemicals Inc
Original Assignee
Mitsui Toatsu Chemicals Inc
Mochida Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals Inc, Mochida Pharmaceutical Co Ltd filed Critical Mitsui Toatsu Chemicals Inc
Publication of DE69003061D1 publication Critical patent/DE69003061D1/de
Application granted granted Critical
Publication of DE69003061T2 publication Critical patent/DE69003061T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49—Urokinase; Tissue plasminogen activator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE90310287T 1989-09-21 1990-09-20 Protein enthaltende wässerige Lösungen. Expired - Fee Related DE69003061T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1243311A JPH0791318B2 (ja) 1989-09-21 1989-09-21 蛋白質水溶液、蛋白質水溶液の濃度増大方法および蛋白質製剤

Publications (2)

Publication Number Publication Date
DE69003061D1 DE69003061D1 (de) 1993-10-07
DE69003061T2 true DE69003061T2 (de) 1993-12-16

Family

ID=17101947

Family Applications (1)

Application Number Title Priority Date Filing Date
DE90310287T Expired - Fee Related DE69003061T2 (de) 1989-09-21 1990-09-20 Protein enthaltende wässerige Lösungen.

Country Status (14)

Country Link
EP (1) EP0419251B1 (de)
JP (1) JPH0791318B2 (de)
KR (1) KR930004598B1 (de)
CN (1) CN1049356C (de)
AT (1) ATE93731T1 (de)
AU (1) AU627621B2 (de)
BR (1) BR9004693A (de)
CA (1) CA2025315C (de)
DE (1) DE69003061T2 (de)
DK (1) DK0419251T3 (de)
ES (1) ES2060057T3 (de)
FI (1) FI98891C (de)
NO (1) NO904120L (de)
NZ (1) NZ235297A (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69635051T2 (de) * 1995-06-07 2006-06-14 Chiron Corp Methode zur lösung, reinigung und rückfaltung von protein
US20040033228A1 (en) 2002-08-16 2004-02-19 Hans-Juergen Krause Formulation of human antibodies for treating TNF-alpha associated disorders
MY150740A (en) 2002-10-24 2014-02-28 Abbvie Biotechnology Ltd Low dose methods for treating disorders in which tnf? activity is detrimental
MX2009010361A (es) 2007-03-29 2009-10-16 Abbott Lab Anticuerpos il-12 anti-humanos cristalinos.
US8883146B2 (en) 2007-11-30 2014-11-11 Abbvie Inc. Protein formulations and methods of making same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2107185A (en) * 1981-10-07 1983-04-27 John Kenneth Mcmullen Insulin formulations containing surface-active agents
EP0156169B1 (de) * 1984-02-29 1991-12-18 Asahi Kasei Kogyo Kabushiki Kaisha Wässrige Lösung eines darin in erhöhter Konzentration aufgelösten Gewebe-Plasminogen-Aktivators und Herstellungsverfahren
DE3512908A1 (de) * 1985-04-11 1986-10-23 Behringwerke Ag, 3550 Marburg Gewebe-plasminogenaktivator (t-pa) enthaltendes mittel
JPS61289886A (ja) * 1985-06-19 1986-12-19 Agency Of Ind Science & Technol 酵素及び／又は微生物含有アルギン酸繊維紙の製造法
CA1292686C (en) * 1986-10-27 1991-12-03 Ze'ev Shaked Pharmaceutical compositions of recombinant interleukin-2 and formulation process
US4857320A (en) * 1987-02-19 1989-08-15 Monsanto Company Method of enhancing the solubility of tissue plasminogen activator
JPH02111726A (ja) * 1988-10-19 1990-04-24 Dainippon Pharmaceut Co Ltd ヒト　インターロイキン１を安定化する方法

Also Published As

Publication number Publication date
ATE93731T1 (de) 1993-09-15
EP0419251B1 (de) 1993-09-01
BR9004693A (pt) 1991-09-10
FI98891B (fi) 1997-05-30
CN1050327A (zh) 1991-04-03
CN1049356C (zh) 2000-02-16
JPH03106898A (ja) 1991-05-07
AU6246690A (en) 1991-03-28
KR910005884A (ko) 1991-04-27
NO904120L (no) 1991-03-22
EP0419251A1 (de) 1991-03-27
CA2025315A1 (en) 1991-03-22
NO904120D0 (no) 1990-09-20
NZ235297A (en) 1992-12-23
FI98891C (fi) 1997-09-10
ES2060057T3 (es) 1994-11-16
AU627621B2 (en) 1992-08-27
DK0419251T3 (da) 1994-01-31
DE69003061D1 (de) 1993-10-07
KR930004598B1 (ko) 1993-06-01
JPH0791318B2 (ja) 1995-10-04
FI904618A0 (fi) 1990-09-19
CA2025315C (en) 1997-01-07

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: MOCHIDA PHARMACEUTICAL CO., LTD., TOKIO/TOKYO, JP

8327 Change in the person/name/address of the patent owner

Owner name: MITSUI CHEMICALS, INC., TOKIO/TOKYO, JP

8339 Ceased/non-payment of the annual fee