DE68922850T2 - Verfahren zur herstellung von 2,4,6-triiodo-5-amino-n-alkyl-isophthalsäure. - Google Patents

Verfahren zur herstellung von 2,4,6-triiodo-5-amino-n-alkyl-isophthalsäure.

Info

Publication number
DE68922850T2
DE68922850T2 DE68922850T DE68922850T DE68922850T2 DE 68922850 T2 DE68922850 T2 DE 68922850T2 DE 68922850 T DE68922850 T DE 68922850T DE 68922850 T DE68922850 T DE 68922850T DE 68922850 T2 DE68922850 T2 DE 68922850T2
Authority
DE
Germany
Prior art keywords
substrate
amino
iodine halide
added
instant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68922850T
Other languages
English (en)
Other versions
DE68922850D1 (de
Inventor
Gregory Cross
Robert Chapman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mallinckrodt Inc
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Publication of DE68922850D1 publication Critical patent/DE68922850D1/de
Application granted granted Critical
Publication of DE68922850T2 publication Critical patent/DE68922850T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
DE68922850T 1988-04-06 1989-03-29 Verfahren zur herstellung von 2,4,6-triiodo-5-amino-n-alkyl-isophthalsäure. Expired - Lifetime DE68922850T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17824588A 1988-04-06 1988-04-06
PCT/US1989/001297 WO1989009766A2 (en) 1988-04-06 1989-03-29 Process for the preparation of 2,4,6-triiodo-5-amino-n-alkylisophthalamic acid

Publications (2)

Publication Number Publication Date
DE68922850D1 DE68922850D1 (de) 1995-06-29
DE68922850T2 true DE68922850T2 (de) 1995-12-21

Family

ID=22651791

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68922850T Expired - Lifetime DE68922850T2 (de) 1988-04-06 1989-03-29 Verfahren zur herstellung von 2,4,6-triiodo-5-amino-n-alkyl-isophthalsäure.

Country Status (7)

Country Link
EP (1) EP0408654B1 (de)
JP (1) JP2640381B2 (de)
AT (1) ATE123018T1 (de)
AU (3) AU623403B2 (de)
CA (1) CA1331626C (de)
DE (1) DE68922850T2 (de)
WO (1) WO1989009766A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5013865A (en) * 1988-04-06 1991-05-07 Mallinckrodt, Inc. Process for the preparation of 2,4,6-triiodo-5-amino-N-alkylisophthalamic acid and 2,4,6-triiodo-5-amino-isophthalamide compounds
US6137006A (en) * 1997-05-23 2000-10-24 Nycomed Imaging As Preparation of tri-iodo benzene compounds
GB9710725D0 (en) * 1997-05-23 1997-07-16 Nycomed Imaging As Process
GB9710728D0 (en) * 1997-05-23 1997-07-16 Nycomed Imaging As Method

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD49852A (de) *
US3145197A (en) * 1961-06-26 1964-08-18 Mallinckrodt Chemical Works 5-acetamido-nu-alkyl-2, 4, 6-trhodoiso-phthalamic acid compounds
CA1327600C (en) * 1987-05-22 1994-03-08 Ernest Felder Process for the preparation of 5-acylamino-2,4,6- triiodo-or tribromo-benzoic acid derivatives and corresponding novel 5-acylamino-2,4,6-triiodo or tribromo-benzoic acid derivatives obtained by said process
US5013865A (en) * 1988-04-06 1991-05-07 Mallinckrodt, Inc. Process for the preparation of 2,4,6-triiodo-5-amino-N-alkylisophthalamic acid and 2,4,6-triiodo-5-amino-isophthalamide compounds
DE3937118A1 (de) * 1989-11-03 1991-05-08 Schering Ag Nichtionische roentgenkontrastmittel mit hohem jodgehalt

Also Published As

Publication number Publication date
AU3441889A (en) 1989-11-03
AU1028592A (en) 1992-02-27
AU651167B2 (en) 1994-07-14
WO1989009766A2 (en) 1989-10-19
JPH03505086A (ja) 1991-11-07
AU1010992A (en) 1992-02-27
AU623403B2 (en) 1992-05-14
AU639627B2 (en) 1993-07-29
JP2640381B2 (ja) 1997-08-13
DE68922850D1 (de) 1995-06-29
ATE123018T1 (de) 1995-06-15
CA1331626C (en) 1994-08-23
EP0408654B1 (de) 1995-05-24
WO1989009766A3 (en) 1989-11-16
EP0408654A1 (de) 1991-01-23

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Legal Events

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