DE60328511D1 - Verwendung von temperatur- und strömungsprofilen bei analytischen prozessen auf gradientenelutionsbasis - Google Patents

Verwendung von temperatur- und strömungsprofilen bei analytischen prozessen auf gradientenelutionsbasis

Info

Publication number
DE60328511D1
DE60328511D1 DE60328511T DE60328511T DE60328511D1 DE 60328511 D1 DE60328511 D1 DE 60328511D1 DE 60328511 T DE60328511 T DE 60328511T DE 60328511 T DE60328511 T DE 60328511T DE 60328511 D1 DE60328511 D1 DE 60328511D1
Authority
DE
Germany
Prior art keywords
temperature
matrix
control device
interface
flow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60328511T
Other languages
English (en)
Inventor
Terry L Sheehan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Varian Inc
Original Assignee
Varian Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Varian Inc filed Critical Varian Inc
Application granted granted Critical
Publication of DE60328511D1 publication Critical patent/DE60328511D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G01N30/724—Nebulising, aerosol formation or ionisation
    • G01N30/7266—Nebulising, aerosol formation or ionisation by electric field, e.g. electrospray
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G01N30/7273—Desolvation chambers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE60328511T 2002-10-30 2003-10-29 Verwendung von temperatur- und strömungsprofilen bei analytischen prozessen auf gradientenelutionsbasis Expired - Lifetime DE60328511D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42246502P 2002-10-30 2002-10-30
PCT/US2003/034442 WO2004042384A1 (en) 2002-10-30 2003-10-29 Use of temperature and flow profiles in gradient elution based analytical process

Publications (1)

Publication Number Publication Date
DE60328511D1 true DE60328511D1 (de) 2009-09-03

Family

ID=32312512

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60328511T Expired - Lifetime DE60328511D1 (de) 2002-10-30 2003-10-29 Verwendung von temperatur- und strömungsprofilen bei analytischen prozessen auf gradientenelutionsbasis

Country Status (8)

Country Link
US (1) US7547555B2 (de)
EP (1) EP1561102B1 (de)
JP (1) JP4515265B2 (de)
AT (1) ATE437359T1 (de)
AU (1) AU2003286782A1 (de)
CA (1) CA2503069A1 (de)
DE (1) DE60328511D1 (de)
WO (1) WO2004042384A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008544286A (ja) * 2005-06-24 2008-12-04 ウオーターズ・インベストメンツ・リミテツド 質量分析計インタフェースハウジング
WO2009029232A1 (en) 2007-08-24 2009-03-05 Millipore Corporation System and method for diversion of a liquid chromatography eluant
WO2009029231A2 (en) 2007-08-24 2009-03-05 Millipore Corporation Method of detecting filter extractables in biopharmaceutical products by liquid chromatography-mass spectrometry
CN102279236A (zh) * 2010-06-08 2011-12-14 江苏天瑞仪器股份有限公司 色谱质谱联用仪
US20140166875A1 (en) 2010-09-02 2014-06-19 Wayne State University Systems and methods for high throughput solvent assisted ionization inlet for mass spectrometry
EP2612345B1 (de) * 2010-09-02 2020-04-08 University of the Sciences in Philadelphia System und verfahren zur ionisation von molekülen für die massenspektrometrie und ionenmobilitätsspektrometrie
WO2012058248A2 (en) * 2010-10-25 2012-05-03 Wayne State University Systems and methods extending the laserspray ionization mass spectrometry concept from atmospheric pressure to vacuum
US8410434B1 (en) * 2011-09-16 2013-04-02 Science & Engineering Services, Inc. Thermo-stabilized nano- and micro- flow LC/ESI-MS interface and a method thereof
US10287180B1 (en) * 2015-01-05 2019-05-14 Sutro Connect Inc. Water monitoring device with replaceable reagent cartridge
CN110446921A (zh) * 2017-03-16 2019-11-12 株式会社岛津制作所 带电粒子的供给控制方法和装置
US11764049B2 (en) * 2020-04-14 2023-09-19 Waters Technologies Corporation Coaxial introduction of calibrant in a flow path with analyte to an ion source
US20230015697A1 (en) * 2021-07-13 2023-01-19 Citrix Systems, Inc. Application programming interface (api) authorization

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59135467U (ja) * 1983-02-28 1984-09-10 日本電子株式会社 液体クロマトグラフ質量分析装置
US4814612A (en) * 1983-08-30 1989-03-21 Research Corporation Method and means for vaporizing liquids for detection or analysis
US4958529A (en) * 1989-11-22 1990-09-25 Vestec Corporation Interface for coupling liquid chromatography to solid or gas phase detectors
JPH0712797A (ja) * 1993-06-24 1995-01-17 Hitachi Ltd 質量分析装置
JP3379510B2 (ja) * 1993-12-09 2003-02-24 株式会社日立製作所 液体クロマトグラフ結合型質量分析装置
JP3087548B2 (ja) * 1993-12-09 2000-09-11 株式会社日立製作所 液体クロマトグラフ結合型質量分析装置
US5412208A (en) * 1994-01-13 1995-05-02 Mds Health Group Limited Ion spray with intersecting flow
JPH0943202A (ja) * 1995-07-27 1997-02-14 Shimadzu Corp 液体クロマトグラフ質量分析装置
JPH1078421A (ja) * 1996-09-03 1998-03-24 Hitachi Ltd 液体クロマトグラフ質量分析計
JPH11326302A (ja) * 1998-05-13 1999-11-26 Shimadzu Corp 液体クロマトグラフ質量分析装置
JP2000055880A (ja) * 1998-08-06 2000-02-25 Shimadzu Corp 液体クロマトグラフ質量分析装置
JP4023056B2 (ja) * 1999-12-22 2007-12-19 株式会社島津製作所 液体クロマトグラフ質量分析計
US7069151B2 (en) * 2000-02-08 2006-06-27 Regents Of The University Of Michigan Mapping of differential display of proteins
CA2406546A1 (en) * 2000-05-23 2001-11-29 Discovery Partners International, Inc. High-throughput purification process
JP2002015697A (ja) * 2000-06-30 2002-01-18 Jeol Ltd エレクトロスプレー・イオン源
US6484560B1 (en) * 2000-11-07 2002-11-26 Agilent Technologies, Inc. In Situ concentration of an analyte
JP3422992B2 (ja) * 2001-07-23 2003-07-07 株式会社日立製作所 質量分析計

Also Published As

Publication number Publication date
WO2004042384A1 (en) 2004-05-21
EP1561102A1 (de) 2005-08-10
JP2006504972A (ja) 2006-02-09
AU2003286782A1 (en) 2004-06-07
US20070048187A1 (en) 2007-03-01
JP4515265B2 (ja) 2010-07-28
ATE437359T1 (de) 2009-08-15
CA2503069A1 (en) 2004-05-21
EP1561102B1 (de) 2009-07-22
US7547555B2 (en) 2009-06-16

Similar Documents

Publication Publication Date Title
DE60328511D1 (de) Verwendung von temperatur- und strömungsprofilen bei analytischen prozessen auf gradientenelutionsbasis
DE69622086D1 (de) Thermisches Dämmungssystem in analytischem Instrument
EP0707209A3 (de) Temperaturregelung in tragbarem analytischen Instrument
EP0492927B1 (de) Verfahren zum Steuern der Flüssigkeitsversorgung eines chromatographischen Detektors
US10126276B2 (en) Gas chromatograph-mass spectrometer
EP1891430B1 (de) Verfahren zur kühlung einer gaschromatographischen säule
US20150059450A1 (en) Column oven and liquid chromatograph
US9625428B2 (en) Modulated flame gas flow rates in flame-based detectors
JP4701855B2 (ja) ガスクロマトグラフ質量分析装置
ITBO20030348A1 (it) Camera per sensori di gas e metodo di rilevamento di odori.
US7984638B2 (en) Gas chromatograph oven
JP6891772B2 (ja) マルチディメンジョナルガスクロマトグラフ
US20180238840A1 (en) Gas chromatograph
CN111060636A (zh) 温控分析装置及具备该温控分析装置的在线分析系统
CN106644664A (zh) 一种基于苯基化衍生有机汞热解析‑气相分离‑热裂解系统
US8549894B2 (en) Gas chromatography with ambient pressure stability control
US5337619A (en) Radiant energy sample heating and temperature control
JP2015117955A (ja) クロマトグラム表示方法、並びに、クロマトグラム表示装置及びこれを備えたクロマトグラフ
JP4840015B2 (ja) 液体クロマトグラフシステム
EP0959351A3 (de) Verfahren und Vorrichtung für die Einführung von grossen Proben in Kapillarsäulen für die Gaschromatographie
US7651866B2 (en) Purge and trap concentrator with electrically adjusted purge flow
JPH11118778A (ja) 熱分析装置
WO2021021166A1 (en) Systems and methods for improving detection accuracy in electronic trace detectors
JP2010160053A (ja) ガスクロマトグラフ及びガスクロマトグラフ分析方法
US11609214B2 (en) Systems and methods for improving detection accuracy in electronic trace detectors

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
R082 Change of representative

Ref document number: 1561102

Country of ref document: EP

Representative=s name: KAHLER, KAECK & MOLLEKOPF, 86899 LANDSBERG, DE