DE60327438D1 - Amino-substituierte cyclohexan derivate zur behandlung bakterieller infektionen - Google Patents

Amino-substituierte cyclohexan derivate zur behandlung bakterieller infektionen

Info

Publication number
DE60327438D1
DE60327438D1 DE60327438T DE60327438T DE60327438D1 DE 60327438 D1 DE60327438 D1 DE 60327438D1 DE 60327438 T DE60327438 T DE 60327438T DE 60327438 T DE60327438 T DE 60327438T DE 60327438 D1 DE60327438 D1 DE 60327438D1
Authority
DE
Germany
Prior art keywords
derivatives
amino
treatment
bacterial infections
substituted cyclohexan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60327438T
Other languages
German (de)
English (en)
Inventor
Jeffrey Michael Axten
Robert A Daines
David Thomas Davies
Timothy Francis Gallagher
Graham Elgin Jones
William Henry Miller
Neil David Pearson
Israil Pendrak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DE60327438D1 publication Critical patent/DE60327438D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DE60327438T 2002-06-26 2003-06-25 Amino-substituierte cyclohexan derivate zur behandlung bakterieller infektionen Expired - Lifetime DE60327438D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39170002P 2002-06-26 2002-06-26
US46096103P 2003-04-07 2003-04-07
PCT/EP2003/006756 WO2004002992A1 (en) 2002-06-26 2003-06-25 Compounds

Publications (1)

Publication Number Publication Date
DE60327438D1 true DE60327438D1 (de) 2009-06-10

Family

ID=30003201

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60327438T Expired - Lifetime DE60327438D1 (de) 2002-06-26 2003-06-25 Amino-substituierte cyclohexan derivate zur behandlung bakterieller infektionen

Country Status (10)

Country Link
US (2) US7622481B2 (enExample)
EP (1) EP1537123B1 (enExample)
JP (1) JP4522262B2 (enExample)
AR (1) AR040335A1 (enExample)
AT (1) ATE430154T1 (enExample)
AU (1) AU2003266949A1 (enExample)
DE (1) DE60327438D1 (enExample)
ES (1) ES2325831T3 (enExample)
TW (1) TW200406413A (enExample)
WO (1) WO2004002992A1 (enExample)

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JP2012505866A (ja) 2008-10-17 2012-03-08 グラクソ グループ リミテッド 抗菌剤として使用される三環式窒素化合物
WO2010045987A1 (en) * 2008-10-23 2010-04-29 Glaxo Group Limited Substituted (aza) -1-methyl-1h-quin0lin-2-0nes as antibacterials
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JP5653935B2 (ja) 2009-01-15 2015-01-14 グラクソ グループ リミテッドＧｌａｘｏ Ｇｒｏｕｐ Ｌｉｍｉｔｅｄ 抗菌薬として有用なナフチリジン―２（１ｈ）−オン化合物
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AR102256A1 (es) 2014-10-15 2017-02-15 Actelion Pharmaceuticals Ltd Derivados biaromáticos básicos antibacterianos con sustitución de aminoalcoxi
RS61013B1 (sr) 2014-10-24 2020-11-30 Landos Biopharma Inc Terapeutski preparati zasnovani na lantionin sintetazi c- sličnom proteinu-2
UY36851A (es) * 2015-08-16 2017-03-31 Glaxosmithkline Ip Dev Ltd Compuestos para uso en aplicaciones antibacterianas
WO2019032956A1 (en) 2017-08-10 2019-02-14 President And Fellows Of Harvard College LINCONSAMIDE ANTIBIOTICS AND USES THEREOF
EP3664799B1 (en) * 2017-08-10 2025-10-01 President And Fellows Of Harvard College Lincosamide antibiotics and uses thereof
EA202091325A1 (ru) 2017-11-30 2020-08-28 Лэндос Байофарма, Инк. Способы лечения с помощью лигандов лантионин c-подобного белка 2 и подготовленных с их помощью клеток
CN108003100A (zh) * 2017-12-20 2018-05-08 北京六合宁远科技有限公司 一种药物中间体含氮杂环的胺类化合物的合成方法
JP7430852B2 (ja) 2019-12-20 2024-02-14 エヌイミューン バイオファーマ インコーポレイテッド ランチオニンｃ様タンパク質２リガンド、それを用いて調製される細胞、およびそれを使用する療法
CN116102537B (zh) * 2021-11-10 2024-10-01 四川大学 一种喹啉酮类衍生物及其制备方法和用途
JP2025501056A (ja) 2021-12-30 2025-01-17 シャンハイ ハンソー バイオメディカル カンパニー リミテッド 三環系誘導体阻害剤、その製造方法と応用

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Also Published As

Publication number Publication date
ES2325831T3 (es) 2009-09-21
JP4522262B2 (ja) 2010-08-11
ATE430154T1 (de) 2009-05-15
US7622481B2 (en) 2009-11-24
WO2004002992A1 (en) 2004-01-08
JP2005539087A (ja) 2005-12-22
US20100081650A1 (en) 2010-04-01
EP1537123A1 (en) 2005-06-08
US20060189604A1 (en) 2006-08-24
AR040335A1 (es) 2005-03-30
EP1537123B1 (en) 2009-04-29
TW200406413A (en) 2004-05-01
AU2003266949A1 (en) 2004-01-19

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