DE60310958T2 - Synthese und charakterisierung neuer systeme zum hinführen und zur vektorisierung von molekülen von therapeutischem interesse zu targetzellen - Google Patents

Synthese und charakterisierung neuer systeme zum hinführen und zur vektorisierung von molekülen von therapeutischem interesse zu targetzellen Download PDF

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Publication number
DE60310958T2
DE60310958T2 DE60310958T DE60310958T DE60310958T2 DE 60310958 T2 DE60310958 T2 DE 60310958T2 DE 60310958 T DE60310958 T DE 60310958T DE 60310958 T DE60310958 T DE 60310958T DE 60310958 T2 DE60310958 T2 DE 60310958T2
Authority
DE
Germany
Prior art keywords
grafted
producing
chassis
precursor
cyclopeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60310958T
Other languages
German (de)
English (en)
Other versions
DE60310958D1 (de
Inventor
Pascal Dumy
Marie-Christine Favrot
Didier Boturyn
Jean-Luc Coll
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Universite Joseph Fourier Grenoble 1
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Centre National de la Recherche Scientifique CNRS
Universite Joseph Fourier Grenoble 1
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0211614A external-priority patent/FR2844798B1/fr
Application filed by Centre National de la Recherche Scientifique CNRS, Universite Joseph Fourier Grenoble 1, Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Centre National de la Recherche Scientifique CNRS
Application granted granted Critical
Publication of DE60310958D1 publication Critical patent/DE60310958D1/de
Publication of DE60310958T2 publication Critical patent/DE60310958T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE60310958T 2002-09-19 2003-09-19 Synthese und charakterisierung neuer systeme zum hinführen und zur vektorisierung von molekülen von therapeutischem interesse zu targetzellen Expired - Lifetime DE60310958T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US41184502P 2002-09-19 2002-09-19
FR0211614 2002-09-19
US411845P 2002-09-19
FR0211614A FR2844798B1 (fr) 2002-09-19 2002-09-19 Synthese et caracterisation de nouveaux systemes de guidage et de vectorisation de molecules d'interet therapeutique vers des cellules cibles
PCT/FR2003/002773 WO2004026894A2 (fr) 2002-09-19 2003-09-19 Synthese et caracterisation de nouveaux systemes de guidage et de vectorisation de compose doues d’activite therapeutique

Publications (2)

Publication Number Publication Date
DE60310958D1 DE60310958D1 (de) 2007-02-15
DE60310958T2 true DE60310958T2 (de) 2007-10-11

Family

ID=32031840

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60310958T Expired - Lifetime DE60310958T2 (de) 2002-09-19 2003-09-19 Synthese und charakterisierung neuer systeme zum hinführen und zur vektorisierung von molekülen von therapeutischem interesse zu targetzellen

Country Status (8)

Country Link
US (1) US7531622B2 (ja)
EP (1) EP1539804B1 (ja)
JP (1) JP4657721B2 (ja)
AT (1) ATE350393T1 (ja)
AU (1) AU2003299038A1 (ja)
CA (1) CA2499496C (ja)
DE (1) DE60310958T2 (ja)
WO (1) WO2004026894A2 (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2888753B1 (fr) 2005-07-21 2008-04-04 Commissariat Energie Atomique Vecteur cible avec fonction d'imagerie activable
FR2897616B1 (fr) * 2006-02-20 2008-05-30 Univ Grenoble 1 Presentation de motifs de reconnaissance par une matrice multivalente greffee sur un support solide
WO2010076334A2 (en) 2008-12-31 2010-07-08 Centre Leon Berard Intraoperative diagnosis of primary tumors and secondary tumors or metastases
FR2959993B1 (fr) * 2010-05-17 2014-10-17 Commissariat Energie Atomique Nouveaux composes cyclodecapeptides et leurs applications
FR2989280B1 (fr) 2012-04-13 2017-02-24 Univ Claude Bernard Lyon Nanoparticules ultrafines comme agent de contraste multimodal
SG11201701565PA (en) 2014-09-03 2017-03-30 Immunogen Inc Conjugates comprising cell-binding agents and cytotoxic agents
FR3036621B1 (fr) * 2015-05-25 2017-05-19 Fluoptics Traceur fluorescent ciblant multivalent dans le proche infrarouge pour imagerie optique.
FR3072281B1 (fr) 2017-10-13 2020-12-04 Nh Theraguix Nanovecteurs et utilisations, en particulier pour le traitement de tumeurs
CN111233975A (zh) * 2018-11-28 2020-06-05 复旦大学 可靶向整合素的多肽mn及其在制备肿瘤靶向药物中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA200001007A1 (ru) * 1998-03-31 2001-04-23 Дюпон Фармасьютикалз Компани Фармацевтические препараты для визуализации ангиогенных расстройств
US20030125243A1 (en) * 2000-07-20 2003-07-03 Jun Liu Synthesis of cyclic peptides

Also Published As

Publication number Publication date
ATE350393T1 (de) 2007-01-15
EP1539804B1 (fr) 2007-01-03
WO2004026894A2 (fr) 2004-04-01
US7531622B2 (en) 2009-05-12
EP1539804A2 (fr) 2005-06-15
JP2006514919A (ja) 2006-05-18
DE60310958D1 (de) 2007-02-15
US20060173160A1 (en) 2006-08-03
AU2003299038A8 (en) 2004-04-08
JP4657721B2 (ja) 2011-03-23
AU2003299038A1 (en) 2004-04-08
WO2004026894A3 (fr) 2004-06-24
CA2499496C (fr) 2012-04-24
CA2499496A1 (fr) 2004-04-01

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