DE60233754D1 - Biotinzwischenprodukt und verfahren zu dessen herstellung - Google Patents

Biotinzwischenprodukt und verfahren zu dessen herstellung

Info

Publication number
DE60233754D1
DE60233754D1 DE60233754T DE60233754T DE60233754D1 DE 60233754 D1 DE60233754 D1 DE 60233754D1 DE 60233754 T DE60233754 T DE 60233754T DE 60233754 T DE60233754 T DE 60233754T DE 60233754 D1 DE60233754 D1 DE 60233754D1
Authority
DE
Germany
Prior art keywords
substituent
magnesium
zinc
atom
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60233754T
Other languages
English (en)
Inventor
Masahiko Seki
Toshiaki Shimizu
Shin-Ichi Yoshida
Masanori Hatsuda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Mitsubishi Tanabe Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Tanabe Pharma Corp filed Critical Mitsubishi Tanabe Pharma Corp
Application granted granted Critical
Publication of DE60233754D1 publication Critical patent/DE60233754D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic System
    • C07F3/06—Zinc compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C07D233/34—Ethylene-urea
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic System
    • C07F3/02—Magnesium compounds
DE60233754T 2001-12-04 2002-12-04 Biotinzwischenprodukt und verfahren zu dessen herstellung Expired - Lifetime DE60233754D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2001369479 2001-12-04
JP2002209121 2002-07-18
PCT/JP2002/012694 WO2003048131A1 (fr) 2001-12-04 2002-12-04 Intermediaire destine a la biotine et procede de production associe

Publications (1)

Publication Number Publication Date
DE60233754D1 true DE60233754D1 (de) 2009-10-29

Family

ID=26624858

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60233754T Expired - Lifetime DE60233754D1 (de) 2001-12-04 2002-12-04 Biotinzwischenprodukt und verfahren zu dessen herstellung

Country Status (12)

Country Link
US (2) US7335778B2 (de)
EP (2) EP2098528A3 (de)
JP (1) JP4046693B2 (de)
KR (2) KR100592016B1 (de)
CN (1) CN1273453C (de)
AT (1) ATE443050T1 (de)
AU (1) AU2002349398A1 (de)
DE (1) DE60233754D1 (de)
ES (1) ES2330624T3 (de)
IL (1) IL162002A0 (de)
TW (1) TW200300676A (de)
WO (1) WO2003048131A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100560598C (zh) * 2005-07-26 2009-11-18 上海奥锐特国际贸易有限公司 氟替卡松丙酸酯的合成方法
CN101328148B (zh) * 2007-06-20 2012-05-23 浙江医药股份有限公司新昌制药厂 酯交换法合成1,3-二苄基-5-羟甲基-4-烷氧羰基-咪唑啉2-酮的方法
CN101429204B (zh) * 2007-11-08 2010-12-29 浙江医药股份有限公司新昌制药厂 (3aS,4S,6aR)-4-(5'-氧代己基)-四氢噻酚-[3,6-并]咪唑啉-2-酮及其合成方法
CN103724358B (zh) * 2014-01-20 2015-10-28 新发药业有限公司 （3aS,6aR）-1,3-二苄基四氢-4H-噻吩并[3,4-d]咪唑-2,4-（1H）-二酮的制备方法
CN103936759B (zh) * 2014-03-11 2016-01-13 新发药业有限公司 （3aS,6aR）-1,3-二苄基-四氢-4H-噻吩并[3,4-d]咪唑-2,4-（1H）-二酮的简便制备方法
CN103880859B (zh) * 2014-03-11 2015-12-09 新发药业有限公司 （3aS,6aR）-1,3-二苄基四氢-4H-噻吩并[3,4-d]咪唑-2,4-（1H）-二酮的制备方法
CN104530076B (zh) * 2014-12-17 2016-08-17 新发药业有限公司 （3aS,6aR）-1,3-二苄基四氢-4H-噻吩并[3,4-d]咪唑-2,4-（1H）-二酮的合成方法
CN104592146A (zh) * 2015-01-19 2015-05-06 烟台腾辉化工有限公司 一种l-2-氧代噻唑烷-4-羧酸的制备工艺
WO2021224295A1 (en) * 2020-05-07 2021-11-11 Dsm Ip Assets B.V. A process for producing d-biotin intermediates
CN113200996B (zh) * 2021-04-08 2022-10-11 复旦大学 一种戊酸酯的连续流合成方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759513A (fr) 1969-11-29 1971-05-27 Hoffmann La Roche Thiolactone
BE759512A (fr) 1969-11-29 1971-05-27 Hoffmann La Roche Lactone
FR2105655A5 (de) * 1970-09-16 1972-04-28 Rhone Poulenc Sa
JPS4932551A (de) 1972-07-25 1974-03-25
JPS5327279A (en) 1976-08-25 1978-03-14 Yutaka Terashita Electric source device for electronic flash
JPS58190395A (ja) 1982-04-28 1983-11-07 Sumitomo Chem Co Ltd 光学活性なシス−イミダゾリジンジカルボン酸誘導体の製造法
JPS58192886A (ja) 1982-04-30 1983-11-10 Sumitomo Chem Co Ltd 光学活性なラクトンの製造方法
EP0242686B1 (de) 1986-04-19 1992-01-29 MERCK PATENT GmbH Verfahren zur Herstellung von D-(+)-Biotin
JPH0772156B2 (ja) * 1986-07-11 1995-08-02 東ソー株式会社 含フツ素α，β−不飽和カルボン酸の製法
JPH0759222B2 (ja) 1989-08-03 1995-06-28 三菱電機ホーム機器株式会社 炊飯器の制御回路
JPH0672044B2 (ja) 1991-08-02 1994-09-14 旭化成工業株式会社 高純度アルミナ焼結体の製造方法
IT1289910B1 (it) * 1997-01-17 1998-10-19 Zambon Spa Processo per la preparazione di eteroaril-zinco alogenuri
JP4406948B2 (ja) 1998-12-28 2010-02-03 田辺三菱製薬株式会社 ビオチン中間体の製法
JP2001002679A (ja) 1999-06-21 2001-01-09 Tanabe Seiyaku Co Ltd テトラヒドロチエノイミダゾール誘導体及びその製法
US6291681B1 (en) 2000-02-25 2001-09-18 Roche Vitamins Inc. Process for preparing biotin
DE10024776C1 (de) * 2000-05-19 2001-09-06 Goldschmidt Ag Th Verwendung von Metallhydrid-behandeltem Zink in der metallorganischen Synthese
FR2826963B1 (fr) * 2001-07-04 2006-01-27 Rhodia Chimie Sa Preparation d'organozinciques aromatiques et composition pour ce faire

Also Published As

Publication number Publication date
EP1462444A4 (de) 2006-10-11
KR20060029197A (ko) 2006-04-04
KR100592016B1 (ko) 2006-06-22
CN1564813A (zh) 2005-01-12
US7335778B2 (en) 2008-02-26
EP1462444A1 (de) 2004-09-29
JP4046693B2 (ja) 2008-02-13
US20050038260A1 (en) 2005-02-17
JPWO2003048131A1 (ja) 2005-04-14
US7799929B2 (en) 2010-09-21
CN1273453C (zh) 2006-09-06
TWI310311B (de) 2009-06-01
WO2003048131A1 (fr) 2003-06-12
EP2098528A2 (de) 2009-09-09
ES2330624T3 (es) 2009-12-14
KR100589550B1 (ko) 2006-06-14
IL162002A0 (en) 2005-11-20
EP1462444B1 (de) 2009-09-16
KR20050044683A (ko) 2005-05-12
EP2098528A3 (de) 2011-03-02
TW200300676A (en) 2003-06-16
ATE443050T1 (de) 2009-10-15
US20080119655A1 (en) 2008-05-22
AU2002349398A1 (en) 2003-06-17

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Legal Events

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8364 No opposition during term of opposition