DE60209380T2 - Kaffeepflanze mit verringerter alpha-d-galaktosidase-aktivität - Google Patents
Kaffeepflanze mit verringerter alpha-d-galaktosidase-aktivität Download PDFInfo
- Publication number
- DE60209380T2 DE60209380T2 DE60209380T DE60209380T DE60209380T2 DE 60209380 T2 DE60209380 T2 DE 60209380T2 DE 60209380 T DE60209380 T DE 60209380T DE 60209380 T DE60209380 T DE 60209380T DE 60209380 T2 DE60209380 T2 DE 60209380T2
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- Prior art keywords
- coffee
- galactosidase
- plant
- mrna
- antisense
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8245—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified carbohydrate or sugar alcohol metabolism, e.g. starch biosynthesis
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nutrition Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Tea And Coffee (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01124160 | 2001-10-10 | ||
| EP01124160 | 2001-10-10 | ||
| PCT/EP2002/009148 WO2003032713A2 (en) | 2001-10-10 | 2002-08-15 | COFFEE PLANT WITH REDUCED α-D-GALACTOSIDASE ACTIVITY |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60209380D1 DE60209380D1 (de) | 2006-04-27 |
| DE60209380T2 true DE60209380T2 (de) | 2006-10-19 |
Family
ID=8178911
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60209380T Expired - Lifetime DE60209380T2 (de) | 2001-10-10 | 2002-08-15 | Kaffeepflanze mit verringerter alpha-d-galaktosidase-aktivität |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7238858B2 (enExample) |
| EP (1) | EP1436402B1 (enExample) |
| JP (1) | JP4276945B2 (enExample) |
| CN (1) | CN1635895A (enExample) |
| AT (1) | ATE318319T1 (enExample) |
| AU (1) | AU2002333434B2 (enExample) |
| BR (1) | BR0213180A (enExample) |
| CA (1) | CA2457821A1 (enExample) |
| CO (1) | CO5580845A2 (enExample) |
| DE (1) | DE60209380T2 (enExample) |
| ES (1) | ES2258173T3 (enExample) |
| MY (1) | MY129821A (enExample) |
| OA (1) | OA12667A (enExample) |
| RU (1) | RU2303349C2 (enExample) |
| WO (1) | WO2003032713A2 (enExample) |
| ZA (1) | ZA200403452B (enExample) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5713377B2 (ja) | 2005-12-28 | 2015-05-07 | ザ スクリプス リサーチ インスティテュート | 薬物標的としての天然アンチセンスおよび非コードｒｎａ転写物 |
| CN102239260B (zh) | 2008-10-03 | 2017-04-12 | 库尔纳公司 | 通过抑制针对载脂蛋白‑a1的天然反义转录物治疗载脂蛋白‑a1相关疾病 |
| KR101840618B1 (ko) | 2008-12-04 | 2018-03-20 | 큐알엔에이, 인크. | 종양 억제 유전자에 대한 천연 안티센스 전사체의 억제에 의해 종양 억제 유전자 관련된 질환의 치료 |
| CA2746003C (en) | 2008-12-04 | 2020-03-31 | Opko Curna, Llc | Treatment of vascular endothelial growth factor (vegf) related diseases by inhibition of natural antisense transcript to vegf |
| ES2629630T3 (es) | 2008-12-04 | 2017-08-11 | Curna, Inc. | Tratamiento de enfermedades relacionadas con eritropoyetina (EPO) mediante inhibición del transcrito antisentido natural a EPO |
| ES2560107T3 (es) | 2009-02-12 | 2016-02-17 | Curna, Inc. | Tratamiento de enfermedades relacionadas con el factor neurotrófico derivado de cerebro (BDNF) por inhibición de transcrito antisentido natural para BDNF |
| CN102482677B (zh) | 2009-03-16 | 2017-10-17 | 库尔纳公司 | 通过抑制nrf2的天然反义转录物治疗核因子(红细胞衍生2)‑样2(nrf2)相关疾病 |
| CA2755404C (en) | 2009-03-17 | 2020-03-24 | Joseph Collard | Treatment of delta-like 1 homolog (dlk1) related diseases by inhibition of natural antisense transcript to dlk1 |
| ES2609655T3 (es) | 2009-05-06 | 2017-04-21 | Curna, Inc. | Tratamiento de enfermedades relacionadas con tristetraprolina (TTP) mediante inhibición de transcrito antisentido natural para TTP |
| EP2427553A4 (en) | 2009-05-06 | 2012-11-07 | Opko Curna Llc | TREATMENT OF LIPID TRANSPORT AND METABOLISM-RELATED DISEASES BY INHIBITING THE NATURAL ANTISENSE TRANSCRIPT AGAINST A LIPID TRANSPORT AND METABOLIC TREATMENT |
| WO2010129861A2 (en) | 2009-05-08 | 2010-11-11 | Curna, Inc. | Treatment of dystrophin family related diseases by inhibition of natural antisense transcript to dmd family |
| US8957037B2 (en) | 2009-05-18 | 2015-02-17 | Curna, Inc. | Treatment of reprogramming factor related diseases by inhibition of natural antisense transcript to a reprogramming factor |
| CN102549158B (zh) | 2009-05-22 | 2017-09-26 | 库尔纳公司 | 通过抑制针对转录因子e3(tfe3)的天然反义转录物来治疗tfe3和胰岛素受体底物蛋白2(irs2)相关的疾病 |
| CA2764683A1 (en) | 2009-05-28 | 2010-12-02 | Joseph Collard | Treatment of antiviral gene related diseases by inhibition of natural antisense transcript to an antiviral gene |
| CN102695797B (zh) | 2009-06-16 | 2018-05-25 | 库尔纳公司 | 通过抑制针对胶原基因的天然反义转录物来治疗胶原基因相关的疾病 |
| JP6128846B2 (ja) | 2009-06-16 | 2017-05-17 | クルナ・インコーポレーテッド | パラオキソナーゼ（ｐｏｎ１）に対する天然アンチセンス転写物の抑制によるｐｏｎ１遺伝子関連疾患の治療 |
| WO2010151671A2 (en) | 2009-06-24 | 2010-12-29 | Curna, Inc. | Treatment of tumor necrosis factor receptor 2 (tnfr2) related diseases by inhibition of natural antisense transcript to tnfr2 |
| ES2583691T3 (es) | 2009-06-26 | 2016-09-21 | Curna, Inc. | Tratamiento de enfermedades relacionadas con un gen del síndrome de Down mediante la inhibición de una transcripción antisentido natural a un gen del síndrome de Down |
| JP2013500017A (ja) | 2009-07-24 | 2013-01-07 | カッパーアールエヌエー，インコーポレイテッド | サ−チュイン（ｓｉｒｔ）への天然アンチセンス転写物の阻止によるサ−チュイン（ｓｉｒｔ）関連疾患の治療 |
| EP2462229B1 (en) | 2009-08-05 | 2016-05-11 | CuRNA, Inc. | Treatment of insulin gene (ins) related diseases by inhibition of natural antisense transcript to an insulin gene (ins) |
| CN102625841A (zh) | 2009-08-11 | 2012-08-01 | 欧科库尔纳有限责任公司 | 通过抑制脂连蛋白(adipoq)的天然反义转录物治疗脂连蛋白(adipoq)相关疾病 |
| CA2771228C (en) | 2009-08-21 | 2020-12-29 | Opko Curna, Llc | Treatment of 'c terminus of hsp70-interacting protein' (chip) related diseases by inhibition of natural antisense transcript to chip |
| KR101892760B1 (ko) | 2009-08-25 | 2018-08-28 | 큐알엔에이, 인크. | ＩＱＧＡＰ에 대한 천연 안티센스 전사체의 억제에 의한 ＧＴＰａｓｅ 활성화 단백질을 함유하는 ＩＱ 모티프(ＩＱＧＡＰ)와 관련된 질환의 치료 |
| JP6175236B2 (ja) | 2009-09-25 | 2017-08-09 | カッパーアールエヌエー，インコーポレイテッド | フィラグリン（ｆｌｇ）の発現および活性の調整によるｆｌｇ関連疾患の処置 |
| NO2513310T3 (enExample) | 2009-12-16 | 2018-03-31 | ||
| CA2782375C (en) | 2009-12-23 | 2023-10-31 | Opko Curna, Llc | Treatment of uncoupling protein 2 (ucp2) related diseases by inhibition of natural antisense transcript to ucp2 |
| NO2516648T3 (enExample) | 2009-12-23 | 2018-04-07 | ||
| WO2011079212A2 (en) * | 2009-12-24 | 2011-06-30 | LifeSpan Extension, LLC | Methods and compositions for identifying, producing and using plant-derived products modulating cell function and aging |
| KR101853508B1 (ko) | 2009-12-29 | 2018-06-20 | 큐알엔에이, 인크. | 종양 단백질 63 (ｐ63)에 대한 천연 안티센스 전사체의 억제에 의한 ｐ63에 관련된 질환의 치료 |
| KR101838305B1 (ko) | 2009-12-29 | 2018-03-13 | 큐알엔에이, 인크. | ＮＲＦ1(Ｎｕｃｌｅａｒ Ｒｅｓｐｉｒａｔｏｒｙ Ｆａｃｔｏｒ 1)에 대한 천연 안티센스 전사체의 억제에 의한 핵 호흡 인자 1 관련된 질환의 치료 |
| CN102791862B (zh) | 2009-12-31 | 2017-04-05 | 库尔纳公司 | 通过抑制胰岛素受体底物2(irs2)和转录因子e3(tfe3)的天然反义转录物而治疗irs2相关疾病 |
| CN102906264B (zh) | 2010-01-04 | 2017-08-04 | 库尔纳公司 | 通过抑制干扰素调节因子8(irf8)的天然反义转录物而治疗irf8相关疾病 |
| JP5963680B2 (ja) | 2010-01-06 | 2016-08-03 | カッパーアールエヌエー，インコーポレイテッド | 膵臓発生遺伝子に対する天然アンチセンス転写物の阻害による膵臓発生遺伝子疾患の治療 |
| CA2786535C (en) | 2010-01-11 | 2019-03-26 | Curna, Inc. | Treatment of sex hormone binding globulin (shbg) related diseases by inhibition of natural antisense transcript to shbg |
| JP5981850B2 (ja) | 2010-01-25 | 2016-08-31 | カッパーアールエヌエー，インコーポレイテッド | ＲＮａｓｅＨ１に対する天然アンチセンス転写物の阻害によるＲＮａｓｅＨ１関連疾患の治療 |
| CN102844435B (zh) | 2010-02-22 | 2017-05-10 | 库尔纳公司 | 通过抑制吡咯啉‑5‑羧酸还原酶1(pycr1)的天然反义转录物而治疗pycr1相关疾病 |
| RU2612884C2 (ru) | 2010-04-02 | 2017-03-13 | Курна, Инк. | Лечение заболеваний, связанных с колониестимулирующим фактором 3 (csf3), путем ингибирования природного антисмыслового транскрипта k csf3 |
| CN102858979B (zh) | 2010-04-09 | 2018-01-26 | 库尔纳公司 | 通过抑制成纤维细胞生长因子21(fgf21)的天然反义转录物而治疗fgf21相关疾病 |
| KR101936011B1 (ko) | 2010-05-03 | 2019-01-07 | 큐알엔에이, 인크. | 시르투인 (sirt)에 대한 자연 안티센스 전사체의 저해에 의한 시르투인 (sirt) 관련된 질환의 치료 |
| TWI531370B (zh) | 2010-05-14 | 2016-05-01 | 可娜公司 | 藉由抑制ｐａｒ４天然反股轉錄本治療ｐａｒ４相關疾病 |
| US8895528B2 (en) | 2010-05-26 | 2014-11-25 | Curna, Inc. | Treatment of atonal homolog 1 (ATOH1) related diseases by inhibition of natural antisense transcript to ATOH1 |
| US8980858B2 (en) | 2010-05-26 | 2015-03-17 | Curna, Inc. | Treatment of methionine sulfoxide reductase a (MSRA) related diseases by inhibition of natural antisense transcript to MSRA |
| KR101914309B1 (ko) | 2010-06-23 | 2018-11-02 | 큐알엔에이, 인크. | 전압 작동 나트륨 통로, 알파 소단위(scna)에 대한 자연 안티센스 전사체의 저해에 의한 전압 작동 나트륨 통로, 알파 소단위(scna) 관련된 질환의 치료 |
| JP5998131B2 (ja) | 2010-07-14 | 2016-09-28 | カッパーアールエヌエー，インコーポレイテッド | Ｄｉｓｃｓｌａｒｇｅｈｏｍｏｌｏｇ（ｄｌｇ）ｄｌｇ１への天然アンチセンス転写物の阻害によるｄｌｇ関連疾患の治療 |
| KR101886457B1 (ko) | 2010-10-06 | 2018-08-07 | 큐알엔에이, 인크. | 시알리다아제 4 (neu4)에 대한 자연 안티센스 전사체의 저해에 의한 neu4 관련된 질환의 치료 |
| WO2012054723A2 (en) | 2010-10-22 | 2012-04-26 | Opko Curna Llc | Treatment of alpha-l-iduronidase (idua) related diseases by inhibition of natural antisense transcript to idua |
| US10000752B2 (en) | 2010-11-18 | 2018-06-19 | Curna, Inc. | Antagonat compositions and methods of use |
| ES2657590T3 (es) | 2010-11-23 | 2018-03-06 | Curna, Inc. | Tratamiento de enfermedades relacionadas con nanog mediante inhibición del transcrito antisentido natural a nanog |
| TWI678375B (zh) | 2011-06-09 | 2019-12-01 | 可娜公司 | 藉由抑制共濟蛋白（ｆｒａｔａｘｉｎ，ｆｘｎ）之天然反股轉錄本治療ｆｘｎ相關疾病 |
| CN103874486A (zh) | 2011-09-06 | 2014-06-18 | 库尔纳公司 | 用小分子治疗与电压门控钠通道的α亚基(SCNxA)相关的疾病 |
| EP2825648B1 (en) | 2012-03-15 | 2018-09-05 | CuRNA, Inc. | Treatment of brain derived neurotrophic factor (bdnf) related diseases by inhibition of natural antisense transcript to bdnf |
| CN102643800B (zh) * | 2012-04-25 | 2014-02-05 | 中国科学院植物研究所 | 一种提取植物dna的方法及其专用试剂盒 |
| GB201708665D0 (en) | 2017-05-31 | 2017-07-12 | Tropic Biosciences Uk Ltd | Compositions and methods for increasing extractability of solids from coffee beans |
| US11555199B2 (en) | 2017-09-19 | 2023-01-17 | Tropic Biosciences UK Limited | Modifying the specificity of plant non-coding RNA molecules for silencing gene expression |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6329191B1 (en) * | 1993-08-30 | 2001-12-11 | Hawaii Biotechnology Group, Inc. | DNA encoding recombinant coffee bean alpha-galactosidase |
| EP1138771A1 (fr) * | 2000-03-30 | 2001-10-04 | Societe Des Produits Nestle S.A. | Endo-Mannanase de café |
-
2002
- 2002-08-15 BR BR0213180-3A patent/BR0213180A/pt not_active IP Right Cessation
- 2002-08-15 DE DE60209380T patent/DE60209380T2/de not_active Expired - Lifetime
- 2002-08-15 OA OA1200400102A patent/OA12667A/en unknown
- 2002-08-15 AT AT02801285T patent/ATE318319T1/de not_active IP Right Cessation
- 2002-08-15 WO PCT/EP2002/009148 patent/WO2003032713A2/en not_active Ceased
- 2002-08-15 EP EP02801285A patent/EP1436402B1/en not_active Expired - Lifetime
- 2002-08-15 CN CNA028200861A patent/CN1635895A/zh active Pending
- 2002-08-15 AU AU2002333434A patent/AU2002333434B2/en not_active Ceased
- 2002-08-15 ES ES02801285T patent/ES2258173T3/es not_active Expired - Lifetime
- 2002-08-15 CA CA002457821A patent/CA2457821A1/en not_active Abandoned
- 2002-08-15 RU RU2004114230/13A patent/RU2303349C2/ru not_active IP Right Cessation
- 2002-08-15 JP JP2003535528A patent/JP4276945B2/ja not_active Expired - Fee Related
- 2002-08-26 MY MYPI20023142A patent/MY129821A/en unknown
-
2004
- 2004-03-19 US US10/804,096 patent/US7238858B2/en not_active Expired - Lifetime
- 2004-04-05 CO CO04032188A patent/CO5580845A2/es not_active Application Discontinuation
- 2004-05-06 ZA ZA200403452A patent/ZA200403452B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2258173T3 (es) | 2006-08-16 |
| OA12667A (en) | 2006-06-19 |
| WO2003032713A2 (en) | 2003-04-24 |
| JP2005505290A (ja) | 2005-02-24 |
| EP1436402B1 (en) | 2006-02-22 |
| US20040199943A1 (en) | 2004-10-07 |
| ZA200403452B (en) | 2006-07-26 |
| EP1436402A2 (en) | 2004-07-14 |
| JP4276945B2 (ja) | 2009-06-10 |
| DE60209380D1 (de) | 2006-04-27 |
| CO5580845A2 (es) | 2005-11-30 |
| WO2003032713A3 (en) | 2003-11-13 |
| RU2303349C2 (ru) | 2007-07-27 |
| MY129821A (en) | 2007-05-31 |
| RU2004114230A (ru) | 2005-04-20 |
| CA2457821A1 (en) | 2003-04-24 |
| US7238858B2 (en) | 2007-07-03 |
| ATE318319T1 (de) | 2006-03-15 |
| CN1635895A (zh) | 2005-07-06 |
| AU2002333434B2 (en) | 2007-12-13 |
| BR0213180A (pt) | 2004-09-14 |
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