DE60208450D1 - Verfahren zur Herstellung von L-Glutamin mittels Fermentation und ein L-Glutamin produzierendes Bakterium - Google Patents
Verfahren zur Herstellung von L-Glutamin mittels Fermentation und ein L-Glutamin produzierendes BakteriumInfo
- Publication number
- DE60208450D1 DE60208450D1 DE60208450T DE60208450T DE60208450D1 DE 60208450 D1 DE60208450 D1 DE 60208450D1 DE 60208450 T DE60208450 T DE 60208450T DE 60208450 T DE60208450 T DE 60208450T DE 60208450 D1 DE60208450 D1 DE 60208450D1
- Authority
- DE
- Germany
- Prior art keywords
- glutamine
- fermentation
- production
- producing bacterium
- bacterium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
- C12N9/0016—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/14—Glutamic acid; Glutamine
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001028163 | 2001-02-05 | ||
JP2001028163 | 2001-02-05 | ||
JP2001162806A JP4560998B2 (ja) | 2001-02-05 | 2001-05-30 | 発酵法によるl−グルタミンの製造法及びl−グルタミン生産菌 |
JP2001162806 | 2001-05-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60208450D1 true DE60208450D1 (de) | 2006-03-30 |
DE60208450T2 DE60208450T2 (de) | 2006-08-24 |
Family
ID=26608914
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60208450T Expired - Lifetime DE60208450T2 (de) | 2001-02-05 | 2002-02-05 | Verfahren zur Herstellung von L-Glutamin mittels Fermentation und ein L-Glutamin produzierendes Bakterium |
Country Status (6)
Country | Link |
---|---|
US (2) | US7262035B2 (de) |
EP (2) | EP1229121B1 (de) |
JP (1) | JP4560998B2 (de) |
CN (1) | CN100457894C (de) |
BR (1) | BRPI0200320B1 (de) |
DE (1) | DE60208450T2 (de) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU756507B2 (en) * | 1998-03-18 | 2003-01-16 | Ajinomoto Co., Inc. | L-glutamic acid-producing bacterium and method for producing L-glutamic acid |
JP4427878B2 (ja) | 1999-08-20 | 2010-03-10 | 味の素株式会社 | 析出を伴う発酵法によるl−グルタミン酸の製造法 |
JP4560998B2 (ja) * | 2001-02-05 | 2010-10-13 | 味の素株式会社 | 発酵法によるl−グルタミンの製造法及びl−グルタミン生産菌 |
JP4599726B2 (ja) | 2001-02-20 | 2010-12-15 | 味の素株式会社 | L−グルタミン酸の製造法 |
EP1424397B1 (de) * | 2002-11-26 | 2011-01-19 | Ajinomoto Co., Inc. | Methode für die Produktion von L-Glutamin und L-Glutamin-produzierendes Bakterium |
JP2004187684A (ja) * | 2002-11-26 | 2004-07-08 | Ajinomoto Co Inc | L−グルタミンの製造法及びl−グルタミン生産菌 |
EP1460128B1 (de) * | 2003-03-03 | 2016-11-30 | Ajinomoto Co., Inc. | Verfahren zur Herstellung von L-Arginin oder L-Lysin mittels Fermentation |
JP4576850B2 (ja) * | 2003-03-03 | 2010-11-10 | 味の素株式会社 | 発酵法によるl−アルギニン又はl−リジンの製造法 |
AU2004236516A1 (en) * | 2003-05-07 | 2004-11-18 | Ajinomoto Co., Inc. | Process for producing L-glutamic acid |
DE10344739A1 (de) * | 2003-09-26 | 2005-04-14 | Degussa Ag | Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien |
JP4898441B2 (ja) * | 2004-06-25 | 2012-03-14 | 協和発酵バイオ株式会社 | 物質の製造法 |
CN101336292B (zh) * | 2005-12-27 | 2013-09-11 | 协和发酵生化株式会社 | 用于生产l-谷氨酰胺的方法 |
JP5064396B2 (ja) | 2006-09-01 | 2012-10-31 | 協和発酵バイオ株式会社 | L‐グルタミンの製造法 |
JP2010041920A (ja) | 2006-12-19 | 2010-02-25 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
JP2010110216A (ja) | 2007-02-20 | 2010-05-20 | Ajinomoto Co Inc | L−アミノ酸または核酸の製造方法 |
JP2010130899A (ja) | 2007-03-14 | 2010-06-17 | Ajinomoto Co Inc | L−グルタミン酸系アミノ酸生産微生物及びアミノ酸の製造法 |
US8771998B2 (en) * | 2008-02-21 | 2014-07-08 | Basf Se | Process for the production of gamma-aminobutyric acid |
JP2012223091A (ja) | 2009-08-25 | 2012-11-15 | Ajinomoto Co Inc | L−アミノ酸の製造法 |
WO2011083860A1 (ja) | 2010-01-08 | 2011-07-14 | 協和発酵バイオ株式会社 | L-アミノ酸の製造法 |
EP2522738B1 (de) | 2010-01-08 | 2022-03-16 | Kyowa Hakko Bio Co., Ltd. | Verfahren zur herstellung von l-glutamin oder l-glutaminsäure |
RU2496867C2 (ru) | 2011-04-25 | 2013-10-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") | Способ получения l-аминокислоты семейства глутамата с использованием коринеформной бактерии |
US9822387B2 (en) | 2011-07-29 | 2017-11-21 | Mitsui Chemicals, Inc. | Microorganism having carbon dioxide fixation pathway introduced thereinto |
PE20141569A1 (es) | 2011-11-11 | 2014-11-08 | Ajinomoto Kk | Metodo para producir una sustancia diana mediante fermentacion |
MY172023A (en) | 2013-01-24 | 2019-11-12 | Mitsui Chemicals Inc | Microorganism having carbon dioxide fixation cycle introduced thereinto |
KR101773755B1 (ko) | 2013-05-13 | 2017-09-01 | 아지노모토 가부시키가이샤 | L-아미노산의 제조법 |
JP2016165225A (ja) | 2013-07-09 | 2016-09-15 | 味の素株式会社 | 有用物質の製造方法 |
JP2016192903A (ja) | 2013-09-17 | 2016-11-17 | 味の素株式会社 | 海藻由来バイオマスからのl−アミノ酸の製造方法 |
CN104736707B (zh) | 2013-10-21 | 2017-08-25 | 味之素株式会社 | 生产l‑氨基酸的方法 |
EP3061828B1 (de) | 2013-10-23 | 2024-08-28 | Ajinomoto Co., Inc. | Verfahren zur herstellung einer zielsubstanz |
CN103695491B (zh) * | 2013-12-24 | 2016-08-24 | 山东民强生物科技股份有限公司 | L-谷氨酰胺的精制方法 |
CN103695492B (zh) * | 2013-12-24 | 2016-04-06 | 山东民强生物科技股份有限公司 | 一种提高l-谷氨酰胺收率的方法 |
CN103667382B (zh) * | 2013-12-24 | 2015-09-02 | 山东民强生物科技股份有限公司 | 一种微生物发酵生产l-谷氨酰胺的方法 |
CN105054068A (zh) * | 2014-01-25 | 2015-11-18 | 北京凯因科技股份有限公司 | 一种酵母谷胱甘肽营养配制品 |
JP6623690B2 (ja) | 2015-10-30 | 2019-12-25 | 味の素株式会社 | グルタミン酸系l−アミノ酸の製造法 |
JP7066977B2 (ja) | 2017-04-03 | 2022-05-16 | 味の素株式会社 | L-アミノ酸の製造法 |
EP3861109A1 (de) | 2018-10-05 | 2021-08-11 | Ajinomoto Co., Inc. | Verfahren zur herstellung einer zielsubstanz durch bakterielle fermentation |
CN113025542B (zh) * | 2019-12-25 | 2022-09-16 | 中国科学院微生物研究所 | 产l-谷氨酰胺的重组大肠杆菌及其构建方法与应用 |
KR102198072B1 (ko) * | 2020-03-04 | 2021-01-04 | 씨제이제일제당 주식회사 | 글루타민 신테타아제 변이형 폴리펩티드 및 이를 이용한 l-글루타민 생산 방법 |
CN113444655B (zh) * | 2020-03-26 | 2023-05-16 | 吉林中粮生化有限公司 | 谷氨酸棒状杆菌、高谷氨酸产量的温度敏感型菌株及其获得方法、应用以及谷氨酸发酵方法 |
KR102216450B1 (ko) * | 2020-03-30 | 2021-02-17 | 대상 주식회사 | 글루타민 생산능을 향상시키는 형질전환용 재조합 벡터 및 이를 도입한 균주 |
CN113201535B (zh) * | 2020-07-20 | 2022-02-08 | 中国科学院天津工业生物技术研究所 | 谷氨酸脱氢酶基因启动子的突变体及其应用 |
JPWO2022092018A1 (de) | 2020-10-28 | 2022-05-05 | ||
CN116761884A (zh) | 2020-11-20 | 2023-09-15 | Cj第一制糖株式会社 | 具有增强的l-谷氨酰胺生产能力的微生物,以及使用该微生物的l-谷氨酰胺生产方法 |
CN112646766B (zh) * | 2020-12-30 | 2023-08-18 | 内蒙古伊品生物科技有限公司 | 一种改造基因bbd29_04920的产l-谷氨酸的重组菌株及其构建方法与应用 |
CN113817627B (zh) * | 2021-07-15 | 2023-04-28 | 大连医诺生物股份有限公司 | 一种嗜乙酰乙酸棒杆菌及以氨态氮浓度控制进行谷氨酰胺发酵的方法 |
CN113684165B (zh) * | 2021-08-12 | 2023-07-25 | 江南大学 | 一种重组谷氨酸棒杆菌及其在生产l-谷氨酰胺中的应用 |
US20240117393A1 (en) | 2022-09-30 | 2024-04-11 | Ajinomoto Co., Inc. | Method for producing l-amino acid |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5317675B2 (de) * | 1972-12-16 | 1978-06-09 | ||
US3888039A (en) * | 1974-01-11 | 1975-06-10 | Quaker Oats Co | Foldable toy building |
GB9111872D0 (en) | 1991-06-03 | 1991-07-24 | Shell Int Research | Polymer process |
EP0756007A3 (de) * | 1995-06-30 | 1997-10-29 | Ajinomoto Kk | Genvermerungsverfahren mit kunstlichen Transposon |
AU756507B2 (en) * | 1998-03-18 | 2003-01-16 | Ajinomoto Co., Inc. | L-glutamic acid-producing bacterium and method for producing L-glutamic acid |
PE20001128A1 (es) * | 1998-10-19 | 2000-11-14 | Ajinomoto Kk | Bacteria productora del acido l-glutamico y procedimiento para obtener el acido l-glutamico |
CN1067434C (zh) | 1998-12-28 | 2001-06-20 | 山东大学 | 一种谷氨酰胺发酵生产工艺 |
ES2177475T1 (es) * | 1999-06-25 | 2002-12-16 | Basf Ag | Genes de corynebacterium glutamicum que codifican proteinas de una ruta metabolica. |
JP4427878B2 (ja) * | 1999-08-20 | 2010-03-10 | 味の素株式会社 | 析出を伴う発酵法によるl−グルタミン酸の製造法 |
JP4304837B2 (ja) * | 2000-07-05 | 2009-07-29 | 味の素株式会社 | L−グルタミン酸生産菌及びl−グルタミン酸の製造法 |
JP4560998B2 (ja) * | 2001-02-05 | 2010-10-13 | 味の素株式会社 | 発酵法によるl−グルタミンの製造法及びl−グルタミン生産菌 |
JP2002238592A (ja) * | 2001-02-20 | 2002-08-27 | Ajinomoto Co Inc | L−グルタミン酸の製造法 |
RU2230114C2 (ru) * | 2001-11-30 | 2004-06-10 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Мутантная глутаминсинтетаза, фрагмент днк, штамм escherichia coli - продуцент l-глутамина и способ получения l-аминокислот |
-
2001
- 2001-05-30 JP JP2001162806A patent/JP4560998B2/ja not_active Expired - Lifetime
-
2002
- 2002-02-04 BR BRPI0200320A patent/BRPI0200320B1/pt active IP Right Grant
- 2002-02-05 US US10/062,458 patent/US7262035B2/en not_active Expired - Lifetime
- 2002-02-05 EP EP02001993A patent/EP1229121B1/de not_active Expired - Lifetime
- 2002-02-05 CN CNB021205817A patent/CN100457894C/zh not_active Expired - Lifetime
- 2002-02-05 EP EP04000167A patent/EP1424398A3/de not_active Withdrawn
- 2002-02-05 DE DE60208450T patent/DE60208450T2/de not_active Expired - Lifetime
-
2006
- 2006-12-27 US US11/616,463 patent/US20070092953A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20030003550A1 (en) | 2003-01-02 |
JP4560998B2 (ja) | 2010-10-13 |
BRPI0200320B1 (pt) | 2016-07-26 |
EP1229121A3 (de) | 2003-03-12 |
CN1384190A (zh) | 2002-12-11 |
EP1424398A3 (de) | 2004-09-22 |
EP1229121A2 (de) | 2002-08-07 |
DE60208450T2 (de) | 2006-08-24 |
US7262035B2 (en) | 2007-08-28 |
EP1424398A2 (de) | 2004-06-02 |
BR0200320A (pt) | 2002-10-29 |
CN100457894C (zh) | 2009-02-04 |
EP1229121B1 (de) | 2006-01-04 |
JP2002300887A (ja) | 2002-10-15 |
US20070092953A1 (en) | 2007-04-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE60208450D1 (de) | Verfahren zur Herstellung von L-Glutamin mittels Fermentation und ein L-Glutamin produzierendes Bakterium | |
DE502004001613D1 (de) | Verfahren zur herstellung von polyamiden | |
DE60128723D1 (de) | Verfahren zur herstellung von bio-resorbierbaren implantaten | |
DE50200540D1 (de) | Verfahren zur Herstellung lösungsmittelfreier Suspensionen | |
DE60203569D1 (de) | Verfahren zur Herstellung von Methanol | |
DE60224643D1 (de) | Verfahren zur herstellung von reifen | |
DE602005016292D1 (de) | Verfahren zur herstellung von glatiramer | |
DE602004028370D1 (de) | Verfahren zur bilderzeugung, bilderzeugungsgerät, zwischenelement, und verfahren zur modifizierung der oberfläche des zwischenelementes | |
DE60143084D1 (de) | Verfahren zur herstellung von glyceriden mittels lipasen | |
DE60204296D1 (de) | Verfahren zur herstellung von einstückigen kolben | |
DE50208864D1 (de) | Verfahren zur herstellung von arylaminen | |
DE60201480D1 (de) | Verfahren zur Herstellung von hochreinem Xylylendiamin | |
DE60206031D1 (de) | Verfahren zur herstellung von seltenerdlegierungs sinterformteilen | |
DE60222645D1 (de) | Verfahren zur herstellung von oxazolidinonen | |
DE60208562D1 (de) | Verfahren zur herstellung von tagatose | |
DE60333291D1 (de) | Verfahren zur herstellung von flachglas | |
DE10197137T1 (de) | Verfahren zur Herstellung von Mikrostrukturen | |
DE602004020895D1 (de) | Verfahren zur herstellung von kohlenstoffnanospulen | |
DE60229194D1 (de) | Verfahren zur Herstellung von Acrylsäure | |
DE502004005626D1 (de) | Verfahren zur herstellung von organoacylphosphiten | |
DE602004007212D1 (de) | Verfahren zur Herstellung von hochwertigen fermentierten Sojabohnenprodukten | |
DE60219800D1 (de) | Verfahren zur herstellung von cilastatin | |
DE60141311D1 (de) | Verfahren zur Herstellung von Diaphragmen | |
DE10394193D2 (de) | Verfahren zur Herstellung von Mikrosystemen | |
DE60239085D1 (de) | Prozess zur Herstellung von E-Caprolactam |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8381 | Inventor (new situation) |
Inventor name: NAKAMURA, JUN, C/O AJINOMOTO CO., KAWASAKI-SHI, KA Inventor name: IZUI, HIROSHI, C/O AJINOMOTO CO., KAWASAKI-SHI, KA Inventor name: MORIGUCHI, KAYO, C/O AJINOMOTO CO., KAWASAKI-SHI, Inventor name: KAWASHIMA, HIROKI, C/O AJINOMOTO CO., KAWASAKI-SHI Inventor name: NAKAMATSU, TSUYOSHI, C/O TOKYO DENKI UNIV. KANADA, Inventor name: KURAHASHI, OSAMU, C/O AJINOMOTO CO., KAWASAKI-SHI, |