DE602007007773D1 - Verfahren zur synthese von ibandronat-natrium - Google Patents

Verfahren zur synthese von ibandronat-natrium

Info

Publication number
DE602007007773D1
DE602007007773D1 DE602007007773T DE602007007773T DE602007007773D1 DE 602007007773 D1 DE602007007773 D1 DE 602007007773D1 DE 602007007773 T DE602007007773 T DE 602007007773T DE 602007007773 T DE602007007773 T DE 602007007773T DE 602007007773 D1 DE602007007773 D1 DE 602007007773D1
Authority
DE
Germany
Prior art keywords
synthesis
ibandronate sodium
present
ibandronate
sodium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602007007773T
Other languages
German (de)
English (en)
Inventor
Dharamaraj Ramchandra Rao
Rajendra Narayanrao Kankan
Maruti Ganpati Ghagare
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cipla Ltd
Original Assignee
Cipla Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cipla Ltd filed Critical Cipla Ltd
Publication of DE602007007773D1 publication Critical patent/DE602007007773D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/04—Sodium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
DE602007007773T 2006-06-23 2007-06-22 Verfahren zur synthese von ibandronat-natrium Active DE602007007773D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN994MU2006 2006-06-23
PCT/IN2007/000255 WO2008035367A2 (en) 2006-06-23 2007-06-22 Process for the synthesis of ibandronate sodium

Publications (1)

Publication Number Publication Date
DE602007007773D1 true DE602007007773D1 (de) 2010-08-26

Family

ID=39144580

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602007007773T Active DE602007007773D1 (de) 2006-06-23 2007-06-22 Verfahren zur synthese von ibandronat-natrium

Country Status (11)

Country Link
US (1) US8178712B2 (https=)
EP (1) EP2038291B1 (https=)
JP (1) JP5571378B2 (https=)
KR (1) KR101425429B1 (https=)
AT (1) ATE473990T1 (https=)
AU (1) AU2007298508B2 (https=)
CA (1) CA2652420C (https=)
DE (1) DE602007007773D1 (https=)
NZ (1) NZ573137A (https=)
WO (1) WO2008035367A2 (https=)
ZA (1) ZA200810024B (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2656053A1 (en) * 2006-07-03 2008-01-10 Generics [Uk] Limited Novel process for the preparation of bisphosphonic acids
CN102093416B (zh) * 2011-03-17 2013-07-24 南京恒生制药有限公司 一种合成伊班膦酸钠的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2534391C2 (de) * 1975-08-01 1983-01-13 Henkel KGaA, 4000 Düsseldorf 1-Hydroxy-3-aminoalkan-1,1-diphosphonsäuren
JPS5414931A (en) * 1977-07-05 1979-02-03 Seitetsu Kagaku Co Ltd Preparation of n-benzylglycine
DE3623397A1 (de) * 1986-07-11 1988-01-14 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
JPS63190868A (ja) * 1986-08-21 1988-08-08 Kanegafuchi Chem Ind Co Ltd 光学活性スルホニルオキシ化合物及びその化合物を用いる光学活性アミンの製造方法
JPH11322687A (ja) * 1998-05-12 1999-11-24 Koei Chem Co Ltd ホルムアミド類の製造方法
JPH11349494A (ja) * 1998-06-03 1999-12-21 Toray Ind Inc 光学分割用分離剤および光学異性体の吸着分離方法
JP2001294558A (ja) * 2000-04-12 2001-10-23 Honshu Chem Ind Co Ltd ノルボルネンー２−カルボン酸エステル類及びその製造方法
JP4642762B2 (ja) * 2003-08-21 2011-03-02 サン・ファーマシューティカル・インダストリーズ・リミテッド ビスホスホン酸化合物の製造方法
JP4191008B2 (ja) * 2003-11-04 2008-12-03 花王株式会社 アミノカルボン酸エステルの製造法
ATE508134T1 (de) 2003-12-23 2011-05-15 Alchymars S P A Amorphe form das natriumsalzes der ibandronsäure
WO2006002348A2 (en) 2004-06-23 2006-01-05 Teva Pharmaceutical Industies Ltd. Solid and crystalline ibandronic acid
US7214818B2 (en) 2004-10-29 2007-05-08 Hoffmann-La Roche Inc. Method for synthesizing bisphosphonate

Also Published As

Publication number Publication date
WO2008035367A3 (en) 2008-05-22
KR20090023394A (ko) 2009-03-04
AU2007298508B2 (en) 2012-02-09
AU2007298508A1 (en) 2008-03-27
CA2652420C (en) 2014-01-14
NZ573137A (en) 2011-03-31
ATE473990T1 (de) 2010-07-15
WO2008035367A2 (en) 2008-03-27
CA2652420A1 (en) 2008-03-27
JP2009541305A (ja) 2009-11-26
EP2038291A2 (en) 2009-03-25
WO2008035367B1 (en) 2008-08-07
US8178712B2 (en) 2012-05-15
KR101425429B1 (ko) 2014-08-01
JP5571378B2 (ja) 2014-08-13
ZA200810024B (en) 2009-10-28
EP2038291B1 (en) 2010-07-14
US20100228052A1 (en) 2010-09-09

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