DE60200627T2 - Verfahren zur Herstellung von (3aS)-5,5-Dioxo-2,3,3a,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazin - Google Patents

Verfahren zur Herstellung von (3aS)-5,5-Dioxo-2,3,3a,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazin Download PDF

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Publication number
DE60200627T2
DE60200627T2 DE60200627T DE60200627T DE60200627T2 DE 60200627 T2 DE60200627 T2 DE 60200627T2 DE 60200627 T DE60200627 T DE 60200627T DE 60200627 T DE60200627 T DE 60200627T DE 60200627 T2 DE60200627 T2 DE 60200627T2
Authority
DE
Germany
Prior art keywords
formula
compound
pyrrolo
dioxo
benzothiadiazine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60200627T
Other languages
German (de)
English (en)
Other versions
DE60200627D1 (de
Inventor
Elsa Foucher
Gilles Thominot
Jean-Pierre Lecouve
James Andrew Ramsden
Christopher James Histon Cobley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Les Laboratoires Servier SAS
Original Assignee
Les Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Les Laboratoires Servier SAS filed Critical Les Laboratoires Servier SAS
Publication of DE60200627D1 publication Critical patent/DE60200627D1/de
Application granted granted Critical
Publication of DE60200627T2 publication Critical patent/DE60200627T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE60200627T 2001-04-18 2002-04-16 Verfahren zur Herstellung von (3aS)-5,5-Dioxo-2,3,3a,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazin Expired - Fee Related DE60200627T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0105226 2001-04-18
FR0105226A FR2823753B1 (fr) 2001-04-18 2001-04-18 Nouveau procede de synthese de la (3as)-5,5-dioxo-2,3,3a, 4-tetrahydro-1h-pyrrolo [2,1-c] [1,2,4] benzothiadiazine

Publications (2)

Publication Number Publication Date
DE60200627D1 DE60200627D1 (de) 2004-07-22
DE60200627T2 true DE60200627T2 (de) 2005-07-14

Family

ID=8862416

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60200627T Expired - Fee Related DE60200627T2 (de) 2001-04-18 2002-04-16 Verfahren zur Herstellung von (3aS)-5,5-Dioxo-2,3,3a,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazin

Country Status (23)

Country Link
US (1) US6518422B2 (show.php)
EP (1) EP1251132B1 (show.php)
JP (1) JP4011956B2 (show.php)
KR (1) KR100468066B1 (show.php)
CN (1) CN1169811C (show.php)
AR (1) AR036871A1 (show.php)
AT (1) ATE269339T1 (show.php)
AU (1) AU782080B2 (show.php)
BR (1) BR0201307A (show.php)
CA (1) CA2382405C (show.php)
DE (1) DE60200627T2 (show.php)
DK (1) DK1251132T3 (show.php)
EA (1) EA004927B1 (show.php)
ES (1) ES2223031T3 (show.php)
FR (1) FR2823753B1 (show.php)
HU (1) HUP0201256A3 (show.php)
MX (1) MXPA02003639A (show.php)
NO (1) NO20021768L (show.php)
NZ (1) NZ518422A (show.php)
PL (1) PL353512A1 (show.php)
PT (1) PT1251132E (show.php)
SI (1) SI1251132T1 (show.php)
ZA (1) ZA200203085B (show.php)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2856065B1 (fr) * 2003-06-13 2005-08-19 Servier Lab Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US20060014887A1 (en) * 2004-07-19 2006-01-19 3M Innovative Properties Company Method of hydrolyzing a dispersion of ionic fluoropolymer
FR2879201B1 (fr) * 2004-12-10 2007-02-16 Servier Lab Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
DK2230094T3 (en) 2009-03-20 2014-03-03 Kremstal Tuerenwerk Gmbh Process for coating of panels

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3294791A (en) * 1966-03-14 1966-12-27 American Home Prod Tetrahydro-2, 5-methano-1, 2, 5-benzothiadiazepine 1, 1-dioxide
US3471483A (en) * 1967-11-09 1969-10-07 American Home Prod 1 - substituted - 2,3,3a - 4 - tetrahydro - 1h-pyrrolo(2,1 - c)(1,2,4)benzothiadiazine,5,5-dioxide
JPH06192272A (ja) * 1992-12-24 1994-07-12 Japan Tobacco Inc 新規なトリアゾロベンゾチアジアジン及びトリアゾロベンゾチアジアゼピン誘導体
FR2722502B1 (fr) * 1994-07-12 1996-08-23 Adir Nouveau derive de benzothiadiazine, son procede depreparation et les compositions pharmaceutiques qui le contiennent
FR2812291B1 (fr) * 2000-07-28 2002-12-13 Adir Nouveaux derives de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
NO20021768L (no) 2002-10-21
ES2223031T3 (es) 2005-02-16
PL353512A1 (en) 2002-10-21
AU782080B2 (en) 2005-06-30
EA200200378A2 (ru) 2002-10-31
MXPA02003639A (es) 2004-11-12
EP1251132A1 (fr) 2002-10-23
EP1251132B1 (fr) 2004-06-16
AU3440502A (en) 2002-10-24
HUP0201256A2 (hu) 2002-12-28
CA2382405C (fr) 2007-03-06
AR036871A1 (es) 2004-10-13
CN1381455A (zh) 2002-11-27
EA004927B1 (ru) 2004-10-28
SI1251132T1 (en) 2004-10-31
DK1251132T3 (da) 2004-10-25
FR2823753B1 (fr) 2004-07-16
DE60200627D1 (de) 2004-07-22
HU0201256D0 (show.php) 2002-06-29
CN1169811C (zh) 2004-10-06
EA200200378A3 (ru) 2002-12-26
US20020161222A1 (en) 2002-10-31
KR20020081148A (ko) 2002-10-26
FR2823753A1 (fr) 2002-10-25
NO20021768D0 (no) 2002-04-15
US6518422B2 (en) 2003-02-11
ZA200203085B (en) 2002-11-25
KR100468066B1 (ko) 2005-01-24
JP4011956B2 (ja) 2007-11-21
HUP0201256A3 (en) 2004-11-29
HK1049668A1 (en) 2003-05-23
BR0201307A (pt) 2003-06-10
JP2003012674A (ja) 2003-01-15
NZ518422A (en) 2002-12-20
PT1251132E (pt) 2004-09-30
CA2382405A1 (fr) 2002-10-18
ATE269339T1 (de) 2004-07-15

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