DE602005027862D1 - Polymer auf basis von polysaccharide für gewebekleber zur medizinischen verwendung - Google Patents
Polymer auf basis von polysaccharide für gewebekleber zur medizinischen verwendungInfo
- Publication number
- DE602005027862D1 DE602005027862D1 DE602005027862T DE602005027862T DE602005027862D1 DE 602005027862 D1 DE602005027862 D1 DE 602005027862D1 DE 602005027862 T DE602005027862 T DE 602005027862T DE 602005027862 T DE602005027862 T DE 602005027862T DE 602005027862 D1 DE602005027862 D1 DE 602005027862D1
- Authority
- DE
- Germany
- Prior art keywords
- polysaccharide
- medical use
- polymer based
- tissue adhesives
- adhesives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
- A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/046—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/08—Polysaccharides
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B9/00—Cellulose xanthate; Viscose
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/333—Polymers modified by chemical after-treatment with organic compounds containing nitrogen
- C08G65/33303—Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing amino group
- C08G65/33306—Polymers modified by chemical after-treatment with organic compounds containing nitrogen containing amino group acyclic
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
- C09J105/00—Adhesives based on polysaccharides or on their derivatives, not provided for in groups C09J101/00 or C09J103/00
- C09J105/02—Dextran; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
- C09J171/00—Adhesives based on polyethers obtained by reactions forming an ether link in the main chain; Adhesives based on derivatives of such polymers
- C09J171/02—Polyalkylene oxides
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G2650/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G2650/28—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type
- C08G2650/50—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule characterised by the polymer type containing nitrogen, e.g. polyetheramines or Jeffamines(r)
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2203/00—Applications
- C08L2203/02—Applications for biomedical use
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2666/00—Composition of polymers characterized by a further compound in the blend, being organic macromolecular compounds, natural resins, waxes or and bituminous materials, non-macromolecular organic substances, inorganic substances or characterized by their function in the composition
- C08L2666/02—Organic macromolecular compounds, natural resins, waxes or and bituminous materials
- C08L2666/26—Natural polymers, natural resins or derivatives thereof according to C08L1/00 - C08L5/00, C08L89/00, C08L93/00, C08L97/00 or C08L99/00
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61689904P | 2004-10-07 | 2004-10-07 | |
PCT/US2005/036251 WO2006042161A2 (en) | 2004-10-07 | 2005-10-06 | Polysaccharide-based polymer tissue adhesive for medical use |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005027862D1 true DE602005027862D1 (de) | 2011-06-16 |
Family
ID=36148968
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005027862T Active DE602005027862D1 (de) | 2004-10-07 | 2005-10-06 | Polymer auf basis von polysaccharide für gewebekleber zur medizinischen verwendung |
Country Status (7)
Country | Link |
---|---|
US (3) | US8431114B2 (de) |
EP (1) | EP1796746B1 (de) |
JP (1) | JP4975627B2 (de) |
CN (1) | CN101035572B (de) |
DE (1) | DE602005027862D1 (de) |
ES (1) | ES2369473T3 (de) |
WO (1) | WO2006042161A2 (de) |
Families Citing this family (75)
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US8790632B2 (en) * | 2004-10-07 | 2014-07-29 | Actamax Surgical Materials, Llc | Polymer-based tissue-adhesive form medical use |
DE602005027862D1 (de) | 2004-10-07 | 2011-06-16 | Du Pont | Polymer auf basis von polysaccharide für gewebekleber zur medizinischen verwendung |
DE102005030011A1 (de) | 2005-06-17 | 2006-12-21 | Aesculap Ag & Co. Kg | Verfahren zur Herstellung von sterilen Polysaccharidlösungen |
US8679537B2 (en) * | 2005-08-24 | 2014-03-25 | Actamaz Surgical Materials, LLC | Methods for sealing an orifice in tissue using an aldol-crosslinked polymeric hydrogel adhesive |
US8679536B2 (en) * | 2005-08-24 | 2014-03-25 | Actamax Surgical Materials, Llc | Aldol-crosslinked polymeric hydrogel adhesives |
JP2007062917A (ja) * | 2005-08-31 | 2007-03-15 | Kyocera Mita Corp | シート搬送装置及びそれを備えた画像形成装置 |
US20070086958A1 (en) * | 2005-10-14 | 2007-04-19 | Medafor, Incorporated | Formation of medically useful gels comprising microporous particles and methods of use |
US7868132B2 (en) * | 2006-04-25 | 2011-01-11 | E. I. Du Pont De Nemours And Company | Method for preparing multi-arm poly (ethylene glycol) amines |
US7960498B2 (en) * | 2006-06-30 | 2011-06-14 | Actamax Surgical Materials, Llc | Tissue adhesives with modified elasticity |
JP2008054858A (ja) * | 2006-08-30 | 2008-03-13 | Toyobo Co Ltd | 2液型接着剤 |
CN101541857B (zh) | 2006-11-27 | 2012-12-12 | 阿克塔马克斯手术器材有限责任公司 | 多官能聚环氧烷、水凝胶和组织粘合剂 |
EP2137219A1 (de) | 2007-04-24 | 2009-12-30 | E. I. Du Pont de Nemours and Company | Verfahren zur herstellung eines polysacchariddialdehyds mit hohem reinheitsgrad |
US20080287633A1 (en) * | 2007-05-18 | 2008-11-20 | Drumheller Paul D | Hydrogel Materials |
JP5165281B2 (ja) * | 2007-06-01 | 2013-03-21 | 株式会社バイオベルデ | 2反応剤型の医療用含水ゲル形成剤、及び、これより得られるヒアルロン酸ゲル |
US20100112063A1 (en) * | 2007-06-28 | 2010-05-06 | Figuly Garret D | Method for preparing a hydrogel adhesive having extended gelation time and decreased degradation time |
US20090035249A1 (en) * | 2007-08-02 | 2009-02-05 | Bhatia Sujata K | Method of inhibiting proliferation of Escherichia coli |
US8241609B2 (en) * | 2007-08-24 | 2012-08-14 | E I Du Pont De Nemours And Company | Method for embolization using liquid embolic materials |
DE102007045066A1 (de) * | 2007-09-20 | 2009-04-02 | Mike Ehrlich | Material zur Blutstillung enthaltend synthetische Peptide oder Polysaccharide |
WO2009064977A2 (en) * | 2007-11-14 | 2009-05-22 | E.I. Du Pont De Nemours And Company | Dextran-based polymer tissue adhesive for medical use |
US8426492B2 (en) | 2007-11-14 | 2013-04-23 | Actamax Surgical Materials, Llc | Oxidized cationic polysaccharide-based polymer tissue adhesive for medical use |
WO2009072146A1 (en) * | 2007-12-07 | 2009-06-11 | Indo-French Center For The Promotion Of Advanced Research | Biocompatible and biodegradable biopolymer matrix |
CN104888263B (zh) * | 2008-01-14 | 2018-11-30 | 北京环球利康科技有限公司 | 生物相容性止血、防粘连、促愈合、外科封闭的变性淀粉材料 |
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US20100015231A1 (en) * | 2008-07-17 | 2010-01-21 | E.I. Du Pont De Nemours And Company | Low swell, long-lived hydrogel sealant |
US8551136B2 (en) | 2008-07-17 | 2013-10-08 | Actamax Surgical Materials, Llc | High swell, long-lived hydrogel sealant |
US9044529B2 (en) | 2008-11-19 | 2015-06-02 | Actamax Surgical Materials, Llc | Hydrogel tissue adhesive formed from aminated polysaccharide and aldehyde-functionalized multi-arm polyether |
US8466327B2 (en) | 2008-11-19 | 2013-06-18 | Actamax Surgical Materials, Llc | Aldehyde-functionalized polyethers and method of making same |
JP5559190B2 (ja) * | 2008-11-19 | 2014-07-23 | アクタマックス サージカル マテリアルズ リミテッド ライアビリティ カンパニー | 繊維状組織シーラントおよびその使用方法 |
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EP2696906B1 (de) | 2011-04-13 | 2015-07-01 | Massachusetts Institute of Technology | Biokompatible klebstoffe und verfahren |
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CN105126157B (zh) * | 2015-09-17 | 2018-02-09 | 爱美客技术发展股份有限公司 | 医用可注射粘合凝胶及其制备方法 |
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CN105709269A (zh) * | 2016-03-01 | 2016-06-29 | 浙江大学 | 一种用于伤口保护的天然高分子液体喷剂 |
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CN111053946B (zh) * | 2019-12-19 | 2022-11-25 | 杭州矩正医疗科技有限公司 | 一种基于多糖和超支化多肽的双组分组织粘合剂及其制备方法 |
CN111388741B (zh) * | 2020-04-01 | 2021-09-07 | 东华大学 | 预载多肽的可注射自修复抗菌水凝胶敷料及其制备方法 |
US11739166B2 (en) | 2020-07-02 | 2023-08-29 | Davol Inc. | Reactive polysaccharide-based hemostatic agent |
CN112521517B (zh) * | 2020-12-10 | 2022-03-01 | 宜宾丝丽雅股份有限公司 | 粘胶纤维生产中的黄化夹套控制系统及方法 |
CN116474173A (zh) * | 2023-05-19 | 2023-07-25 | 吉林大学 | 一种促进骨缺损修复的复合水凝胶制备方法及其应用 |
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-
2005
- 2005-10-06 DE DE602005027862T patent/DE602005027862D1/de active Active
- 2005-10-06 CN CN2005800341768A patent/CN101035572B/zh not_active Expired - Fee Related
- 2005-10-06 US US11/244,756 patent/US8431114B2/en active Active
- 2005-10-06 ES ES05812166T patent/ES2369473T3/es active Active
- 2005-10-06 EP EP05812166A patent/EP1796746B1/de not_active Expired - Fee Related
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2013
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US8771738B2 (en) | 2014-07-08 |
US20060078536A1 (en) | 2006-04-13 |
CN101035572B (zh) | 2010-12-08 |
EP1796746B1 (de) | 2011-05-04 |
ES2369473T3 (es) | 2011-12-01 |
US8715636B2 (en) | 2014-05-06 |
WO2006042161A2 (en) | 2006-04-20 |
WO2006042161A3 (en) | 2006-08-31 |
US8431114B2 (en) | 2013-04-30 |
US20130189221A1 (en) | 2013-07-25 |
US20130190267A1 (en) | 2013-07-25 |
CN101035572A (zh) | 2007-09-12 |
JP4975627B2 (ja) | 2012-07-11 |
JP2008515556A (ja) | 2008-05-15 |
EP1796746A2 (de) | 2007-06-20 |
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