DE602005022878D1 - Mikrofluidische vorrichtung zur analyse und handhabung von flüssigkeiten - Google Patents
Mikrofluidische vorrichtung zur analyse und handhabung von flüssigkeitenInfo
- Publication number
- DE602005022878D1 DE602005022878D1 DE602005022878T DE602005022878T DE602005022878D1 DE 602005022878 D1 DE602005022878 D1 DE 602005022878D1 DE 602005022878 T DE602005022878 T DE 602005022878T DE 602005022878 T DE602005022878 T DE 602005022878T DE 602005022878 D1 DE602005022878 D1 DE 602005022878D1
- Authority
- DE
- Germany
- Prior art keywords
- analysis
- liquids
- handling
- microfluidic device
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/30—Injector mixers
- B01F25/31—Injector mixers in conduits or tubes through which the main component flows
- B01F25/314—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit
- B01F25/3141—Injector mixers in conduits or tubes through which the main component flows wherein additional components are introduced at the circumference of the conduit with additional mixing means other than injector mixers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
- B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
- B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
- B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
- B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
- B01F25/4331—Mixers with bended, curved, coiled, wounded mixing tubes or comprising elements for bending the flow
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502723—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B43/00—Machines, pumps, or pumping installations having flexible working members
- F04B43/02—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
- F04B43/04—Pumps having electric drive
- F04B43/043—Micropumps
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5302—Apparatus specially adapted for immunological test procedures
- G01N33/5304—Reaction vessels, e.g. agglutination plates
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0621—Control of the sequence of chambers filled or emptied
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0636—Integrated biosensor, microarrays
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
- B01L2400/049—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics vacuum
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0605—Valves, specific forms thereof check valves
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0633—Valves, specific forms thereof with moving parts
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/870,717 US7419638B2 (en) | 2003-01-14 | 2004-06-17 | Microfluidic devices for fluid manipulation and analysis |
PCT/US2005/021092 WO2006009724A2 (en) | 2004-06-17 | 2005-06-15 | Microfluidic devices for fluid manipulation and analysis |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005022878D1 true DE602005022878D1 (de) | 2010-09-23 |
Family
ID=34993245
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005022878T Active DE602005022878D1 (de) | 2004-06-17 | 2005-06-15 | Mikrofluidische vorrichtung zur analyse und handhabung von flüssigkeiten |
Country Status (6)
Country | Link |
---|---|
US (6) | US7419638B2 (de) |
EP (1) | EP1773481B1 (de) |
JP (1) | JP4885852B2 (de) |
AT (1) | ATE477049T1 (de) |
DE (1) | DE602005022878D1 (de) |
WO (1) | WO2006009724A2 (de) |
Families Citing this family (160)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6048734A (en) | 1995-09-15 | 2000-04-11 | The Regents Of The University Of Michigan | Thermal microvalves in a fluid flow method |
US8518328B2 (en) * | 2005-12-27 | 2013-08-27 | Honeywell International Inc. | Fluid sensing and control in a fluidic analyzer |
US6692700B2 (en) | 2001-02-14 | 2004-02-17 | Handylab, Inc. | Heat-reduction methods and systems related to microfluidic devices |
US8895311B1 (en) | 2001-03-28 | 2014-11-25 | Handylab, Inc. | Methods and systems for control of general purpose microfluidic devices |
US7323140B2 (en) | 2001-03-28 | 2008-01-29 | Handylab, Inc. | Moving microdroplets in a microfluidic device |
US7010391B2 (en) | 2001-03-28 | 2006-03-07 | Handylab, Inc. | Methods and systems for control of microfluidic devices |
US7829025B2 (en) | 2001-03-28 | 2010-11-09 | Venture Lending & Leasing Iv, Inc. | Systems and methods for thermal actuation of microfluidic devices |
US6852287B2 (en) | 2001-09-12 | 2005-02-08 | Handylab, Inc. | Microfluidic devices having a reduced number of input and output connections |
US7419638B2 (en) | 2003-01-14 | 2008-09-02 | Micronics, Inc. | Microfluidic devices for fluid manipulation and analysis |
WO2005011867A2 (en) | 2003-07-31 | 2005-02-10 | Handylab, Inc. | Processing particle-containing samples |
US20050047967A1 (en) * | 2003-09-03 | 2005-03-03 | Industrial Technology Research Institute | Microfluidic component providing multi-directional fluid movement |
CA2994321C (en) | 2004-05-03 | 2023-08-08 | Handylab, Inc. | A microfluidic device and methods for processing polynucleotide-containing samples |
US8852862B2 (en) | 2004-05-03 | 2014-10-07 | Handylab, Inc. | Method for processing polynucleotide-containing samples |
DE102005052752A1 (de) * | 2005-11-04 | 2007-05-10 | Clondiag Chip Technologies Gmbh | Vorrichtung und Verfahren zum Nachweis von molekularen Wechselwirkungen |
US20060183216A1 (en) * | 2005-01-21 | 2006-08-17 | Kalyan Handique | Containers for liquid storage and delivery with application to microfluidic devices |
US7635594B2 (en) | 2005-05-09 | 2009-12-22 | Theranos, Inc. | Point-of-care fluidic systems and uses thereof |
WO2007005365A2 (en) * | 2005-06-29 | 2007-01-11 | Cascade Microtech, Inc. | A fluid dispensing system |
EP1936383A4 (de) * | 2005-10-13 | 2009-04-29 | Nissui Pharm Co Ltd | Testeinrichtung |
EP1960306A4 (de) * | 2005-11-22 | 2014-04-02 | Mycrolab Diagnostics Pty Ltd | Mikrofluidstrukturen |
US7763453B2 (en) | 2005-11-30 | 2010-07-27 | Micronics, Inc. | Microfluidic mixing and analytic apparatus |
US9056291B2 (en) | 2005-11-30 | 2015-06-16 | Micronics, Inc. | Microfluidic reactor system |
US7485153B2 (en) * | 2005-12-27 | 2009-02-03 | Honeywell International Inc. | Fluid free interface for a fluidic analyzer |
US8182767B2 (en) * | 2005-12-27 | 2012-05-22 | Honeywell International Inc. | Needle-septum interface for a fluidic analyzer |
WO2007106579A2 (en) | 2006-03-15 | 2007-09-20 | Micronics, Inc. | Integrated nucleic acid assays |
DK3088083T3 (en) | 2006-03-24 | 2018-11-26 | Handylab Inc | Method of carrying out PCR down a multi-track cartridge |
US8741230B2 (en) | 2006-03-24 | 2014-06-03 | Theranos, Inc. | Systems and methods of sample processing and fluid control in a fluidic system |
US8088616B2 (en) | 2006-03-24 | 2012-01-03 | Handylab, Inc. | Heater unit for microfluidic diagnostic system |
US10900066B2 (en) | 2006-03-24 | 2021-01-26 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
US7998708B2 (en) | 2006-03-24 | 2011-08-16 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
US11806718B2 (en) | 2006-03-24 | 2023-11-07 | Handylab, Inc. | Fluorescence detector for microfluidic diagnostic system |
US11287421B2 (en) | 2006-03-24 | 2022-03-29 | Labrador Diagnostics Llc | Systems and methods of sample processing and fluid control in a fluidic system |
US8883490B2 (en) | 2006-03-24 | 2014-11-11 | Handylab, Inc. | Fluorescence detector for microfluidic diagnostic system |
US20070280857A1 (en) * | 2006-06-02 | 2007-12-06 | Applera Corporation | Devices and Methods for Positioning Dried Reagent In Microfluidic Devices |
AU2007265628B2 (en) * | 2006-06-23 | 2012-12-06 | Perkinelmer Health Sciences, Inc. | Methods and devices for microfluidic point-of-care immunoassays |
WO2008147382A1 (en) * | 2006-09-27 | 2008-12-04 | Micronics, Inc. | Integrated microfluidic assay devices and methods |
EP2091647A2 (de) | 2006-11-14 | 2009-08-26 | Handylab, Inc. | Mikrofluidisches system für parallele amplifikation und erkennung von polynukleotiden |
US20090042241A1 (en) | 2007-04-06 | 2009-02-12 | California Institute Of Technology | Microfluidic device |
WO2008132871A1 (ja) * | 2007-04-13 | 2008-11-06 | Shimadzu Corporation | 反応容器プレート及び反応処理方法 |
US9186677B2 (en) | 2007-07-13 | 2015-11-17 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
US8324372B2 (en) | 2007-07-13 | 2012-12-04 | Handylab, Inc. | Polynucleotide capture materials, and methods of using same |
US8287820B2 (en) | 2007-07-13 | 2012-10-16 | Handylab, Inc. | Automated pipetting apparatus having a combined liquid pump and pipette head system |
USD621060S1 (en) | 2008-07-14 | 2010-08-03 | Handylab, Inc. | Microfluidic cartridge |
US8182763B2 (en) | 2007-07-13 | 2012-05-22 | Handylab, Inc. | Rack for sample tubes and reagent holders |
US9618139B2 (en) | 2007-07-13 | 2017-04-11 | Handylab, Inc. | Integrated heater and magnetic separator |
US8133671B2 (en) | 2007-07-13 | 2012-03-13 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
US8105783B2 (en) | 2007-07-13 | 2012-01-31 | Handylab, Inc. | Microfluidic cartridge |
US20090136385A1 (en) | 2007-07-13 | 2009-05-28 | Handylab, Inc. | Reagent Tube |
WO2009018473A1 (en) * | 2007-07-31 | 2009-02-05 | Micronics, Inc. | Sanitary swab collection system, microfluidic assay device, and methods for diagnostic assays |
WO2009020435A1 (en) * | 2007-08-07 | 2009-02-12 | Agency For Science, Technology And Research | Integrated microfluidic device for gene synthesis |
EP2040073A1 (de) | 2007-09-20 | 2009-03-25 | Iline Microsystems, S.L. | Mikrofluidische Vorrichtung und Verfahren zur Flüssigkeitsgerinnungs-Zeitbestimmung |
EP2055384A1 (de) * | 2007-10-31 | 2009-05-06 | Leukocare AG | Vorrichtung zum Nachweis von Bestandteilen in einem Fluid |
GB0802084D0 (en) * | 2008-02-05 | 2008-03-12 | Univ Dublin City | Microfluidic device for assessing cell surface interactions |
US9664619B2 (en) * | 2008-04-28 | 2017-05-30 | President And Fellows Of Harvard College | Microfluidic device for storage and well-defined arrangement of droplets |
WO2009139898A2 (en) | 2008-05-16 | 2009-11-19 | President And Fellows Of Harvard College | Valves and other flow control in fluidic systems including microfluidic systems |
USD618820S1 (en) | 2008-07-11 | 2010-06-29 | Handylab, Inc. | Reagent holder |
USD787087S1 (en) | 2008-07-14 | 2017-05-16 | Handylab, Inc. | Housing |
US8512648B2 (en) | 2008-07-29 | 2013-08-20 | Scandinavian Micro Biodevices Aps | Microfluidic device |
JP4722977B2 (ja) * | 2008-08-27 | 2011-07-13 | シャープ株式会社 | 検出器具、分析装置、検出方法および検出器具の制御方法 |
EP2349566B1 (de) | 2008-10-03 | 2016-01-06 | Micronics, Inc. | Mikrofluidikvorrichtung und verfahren zur durchführung von blutgruppenbestimmung und kreuzprobe |
US8448499B2 (en) | 2008-12-23 | 2013-05-28 | C A Casyso Ag | Cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, a corresponding measuring system, and a corresponding method |
ES2391918T3 (es) * | 2008-12-23 | 2012-12-03 | C A Casyso Ag | Un dispositivo de cartucho para un sistema de medida para medir las características viscoelásticas de un líquido de muestra, un sistema de medida correspondiente, y un procedimiento correspondiente |
US9033898B2 (en) | 2010-06-23 | 2015-05-19 | Seventh Sense Biosystems, Inc. | Sampling devices and methods involving relatively little pain |
WO2010101620A2 (en) | 2009-03-02 | 2010-09-10 | Seventh Sense Biosystems, Inc. | Systems and methods for creating and using suction blisters or other pooled regions of fluid within the skin |
US20110105952A1 (en) * | 2009-10-30 | 2011-05-05 | Seventh Sense Biosystems, Inc. | Relatively small devices applied to the skin, modular systems, and methods of use thereof |
US20110105951A1 (en) * | 2009-10-30 | 2011-05-05 | Seventh Sense Biosystems, Inc. | Systems and methods for treating, sanitizing, and/or shielding the skin or devices applied to the skin |
US9041541B2 (en) | 2010-01-28 | 2015-05-26 | Seventh Sense Biosystems, Inc. | Monitoring or feedback systems and methods |
JP5726167B2 (ja) * | 2009-04-13 | 2015-05-27 | マイクロニクス, インコーポレイテッド | マイクロ流体臨床分析器 |
JP5792181B2 (ja) | 2009-11-23 | 2015-10-07 | ブリマン、ミカイル | 炭素系電極の制御された電気化学的活性化 |
CA2786569C (en) | 2010-01-29 | 2019-04-09 | Micronics, Inc. | Sample-to-answer microfluidic cartridge |
ITTO20100068U1 (it) * | 2010-04-20 | 2011-10-21 | Eltek Spa | Dispositivi microfluidici e/o attrezzature per dispositivi microfluidici |
JP2013527458A (ja) * | 2010-05-27 | 2013-06-27 | スリーエム イノベイティブ プロパティズ カンパニー | 試料処理用の一体化されたシステム及び組立品 |
CN103068308B (zh) | 2010-07-16 | 2016-03-16 | 第七感生物系统有限公司 | 用于流体传输装置的低压环境 |
US9182353B2 (en) | 2010-07-22 | 2015-11-10 | Hach Company | Lab-on-a-chip for alkalinity analysis |
US20130158482A1 (en) | 2010-07-26 | 2013-06-20 | Seventh Sense Biosystems, Inc. | Rapid delivery and/or receiving of fluids |
WO2012021801A2 (en) | 2010-08-13 | 2012-02-16 | Seventh Sense Biosystems, Inc. | Systems and techniques for monitoring subjects |
US9387476B2 (en) * | 2010-10-27 | 2016-07-12 | Illumina, Inc. | Flow cells for biological or chemical analysis |
CN103370007B (zh) | 2010-11-09 | 2018-12-18 | 第七感生物系统有限公司 | 用于采血的系统和界面 |
US9157903B2 (en) * | 2011-02-25 | 2015-10-13 | Honeywell International Inc. | Microfluidic separation of plasma for colormetric assay |
BR112013026451B1 (pt) | 2011-04-15 | 2021-02-09 | Becton, Dickinson And Company | sistema e método para realizar ensaios de diagnóstico molecular em várias amostras em paralelo e simultaneamente amplificação em tempo real em pluralidade de câmaras de reação de amplificação |
ES2597081T3 (es) | 2011-04-29 | 2017-01-13 | Seventh Sense Biosystems, Inc. | Entrega y/o recepción de fluidos |
EP2701598A1 (de) | 2011-04-29 | 2014-03-05 | Seventh Sense Biosystems, Inc. | Systeme und verfahren zur flüssigkeitsentnahme aus einer person |
CA2833175A1 (en) * | 2011-04-29 | 2012-11-01 | Seventh Sense Biosystems, Inc. | Devices and methods for collection and/or manipulation of blood spots or other bodily fluids |
US20130158468A1 (en) | 2011-12-19 | 2013-06-20 | Seventh Sense Biosystems, Inc. | Delivering and/or receiving material with respect to a subject surface |
US9599613B2 (en) | 2011-07-20 | 2017-03-21 | University Of Washington Through Its Center For Commercialization | Photonic blood typing |
US9638663B2 (en) | 2011-07-25 | 2017-05-02 | Proxim Diagnostics Corporation | Cartridge for diagnostic testing |
US8975193B2 (en) | 2011-08-02 | 2015-03-10 | Teledyne Dalsa Semiconductor, Inc. | Method of making a microfluidic device |
USD692162S1 (en) | 2011-09-30 | 2013-10-22 | Becton, Dickinson And Company | Single piece reagent holder |
JP6117217B2 (ja) | 2011-09-30 | 2017-04-19 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | ユニット化された試薬ストリップ |
EP2773892B1 (de) | 2011-11-04 | 2020-10-07 | Handylab, Inc. | Vorrichtung zur vorbereitung von polynukleotidproben |
CN104136123B (zh) | 2012-01-09 | 2017-03-01 | 精密公司 | 微流体反应器系统 |
US10031138B2 (en) | 2012-01-20 | 2018-07-24 | University Of Washington Through Its Center For Commercialization | Hierarchical films having ultra low fouling and high recognition element loading properties |
US10822644B2 (en) | 2012-02-03 | 2020-11-03 | Becton, Dickinson And Company | External files for distribution of molecular diagnostic tests and determination of compatibility between tests |
CN102588256B (zh) * | 2012-02-22 | 2014-08-06 | 重庆理工大学 | 一种具有自关闭单向阀的单层双腔真空驱动的蠕动泵 |
US9180449B2 (en) | 2012-06-12 | 2015-11-10 | Hach Company | Mobile water analysis |
KR102054678B1 (ko) * | 2012-07-12 | 2020-01-22 | 삼성전자주식회사 | 유체 분석 카트리지 |
US20150293097A1 (en) | 2012-10-08 | 2015-10-15 | General Electric Company | Preloaded test substrates for testing lal-reactive substances, methods of use, and methods of making |
EP3427830B1 (de) | 2012-10-24 | 2021-06-23 | Genmark Diagnostics Inc. | Integrierte multiplex-zielanalyse |
US20140322706A1 (en) | 2012-10-24 | 2014-10-30 | Jon Faiz Kayyem | Integrated multipelx target analysis |
US10248765B1 (en) | 2012-12-05 | 2019-04-02 | Theranos Ip Company, Llc | Systems, devices, and methods for bodily fluid sample collection, transport, and handling |
US9386948B2 (en) | 2012-12-05 | 2016-07-12 | Theranos, Inc. | Systems, devices, and methods for bodily fluid sample transport |
WO2014089120A1 (en) | 2012-12-07 | 2014-06-12 | Integrated Plasmonics Corporation | Plasmonic spectroscopic sensor and cuvette therefor |
USD768872S1 (en) | 2012-12-12 | 2016-10-11 | Hach Company | Cuvette for a water analysis instrument |
US20140170678A1 (en) * | 2012-12-17 | 2014-06-19 | Leukodx Ltd. | Kits, compositions and methods for detecting a biological condition |
EP2932268A4 (de) | 2012-12-17 | 2016-10-19 | Leukodx Ltd | Systeme und verfahren zum erkennen eines biologischen zustands |
US10610861B2 (en) | 2012-12-17 | 2020-04-07 | Accellix Ltd. | Systems, compositions and methods for detecting a biological condition |
EP3549674B1 (de) | 2012-12-21 | 2020-08-12 | PerkinElmer Health Sciences, Inc. | Filme mit geringere elastizität zur mikrofluidischen verwendung |
KR20150097764A (ko) | 2012-12-21 | 2015-08-26 | 마이크로닉스 인코포레이티드. | 휴대형 형광 검출 시스템 및 미량분석 카트리지 |
JP6498125B2 (ja) | 2012-12-21 | 2019-04-10 | マイクロニクス, インコーポレイテッド | 流体回路および関連する製造方法 |
US9976963B2 (en) * | 2012-12-21 | 2018-05-22 | Integrated Plasmonics Corporation | Microcuvette cartridge |
CN104981698B (zh) | 2013-01-31 | 2017-03-29 | 卢米耐克斯公司 | 流体保持板和分析盒 |
WO2014158248A1 (en) | 2013-03-12 | 2014-10-02 | Integrated Plasmonics Corporation | Optical detection system with tilted sensor |
WO2014143234A1 (en) | 2013-03-14 | 2014-09-18 | Integrated Plasmonics Corporation | Self-aligned spatial filter |
WO2014143235A1 (en) | 2013-03-14 | 2014-09-18 | Integrated Plasmonics Corporation | Ambient light assisted spectroscopy |
US9222623B2 (en) | 2013-03-15 | 2015-12-29 | Genmark Diagnostics, Inc. | Devices and methods for manipulating deformable fluid vessels |
MX365324B (es) * | 2013-03-15 | 2019-05-29 | Theranos Ip Co Llc | Metodos y dispositivos para recoleccion de muestras y separacion de muestras. |
US9506934B2 (en) * | 2013-04-29 | 2016-11-29 | Honeywell International Inc. | Polymer test cartridge mixer for cell lysis |
EP2994532B1 (de) | 2013-05-07 | 2017-11-15 | Micronics, Inc. | Verfahren zur herstellung von nukleinsäurehaltigen proben mittels tonmineralien und alkalischen lösungen |
CA2911308C (en) | 2013-05-07 | 2021-10-19 | Micronics, Inc. | Device for preparation and analysis of nucleic acids |
US10386377B2 (en) | 2013-05-07 | 2019-08-20 | Micronics, Inc. | Microfluidic devices and methods for performing serum separation and blood cross-matching |
JP6560671B2 (ja) | 2013-08-07 | 2019-08-14 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 流体を分注するカートリッジ、自動分析器、および生体試料を分析する方法 |
WO2015102726A2 (en) * | 2013-10-16 | 2015-07-09 | President And Fellows Of Harvard College | A microfluidic device for real-time clinical monitoring and quantitative assessment of whole blood coagulation |
USD881409S1 (en) | 2013-10-24 | 2020-04-14 | Genmark Diagnostics, Inc. | Biochip cartridge |
US9498778B2 (en) | 2014-11-11 | 2016-11-22 | Genmark Diagnostics, Inc. | Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system |
WO2015167492A1 (en) * | 2014-04-30 | 2015-11-05 | Hewlett-Packard Development Company, L.P. | Imaging appratus and methods using diffraction-based illumination |
KR20170016915A (ko) | 2014-06-11 | 2017-02-14 | 마이크로닉스 인코포레이티드. | 핵산의 분석을 위한 통합 검정 대조군을 갖는 마이크로 유체 공학적 카트리지 및 장치 |
US20170197212A1 (en) * | 2014-06-30 | 2017-07-13 | Siemens Healthcare Diagnostics Inc. | Microfluidic test cartridge with no active fluid control |
WO2016033455A1 (en) | 2014-08-29 | 2016-03-03 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Methods, devices, and systems for microfluidic stress emulation |
US10175225B2 (en) | 2014-09-29 | 2019-01-08 | C A Casyso Ag | Blood testing system and method |
US9598722B2 (en) | 2014-11-11 | 2017-03-21 | Genmark Diagnostics, Inc. | Cartridge for performing assays in a closed sample preparation and reaction system |
US10005080B2 (en) | 2014-11-11 | 2018-06-26 | Genmark Diagnostics, Inc. | Instrument and cartridge for performing assays in a closed sample preparation and reaction system employing electrowetting fluid manipulation |
EP3461559A1 (de) | 2015-06-11 | 2019-04-03 | Neofluidics LLC | Manuelle oder elektronische pipettenbetriebene mikrotiterplatte für nanolitertröpfchenlagerung und verfahren zur verwendung davon |
US10537862B2 (en) * | 2015-06-29 | 2020-01-21 | Imec Vzw | Valve-less mixing method and mixing device |
US10371606B2 (en) | 2015-07-21 | 2019-08-06 | Theraos IP Company, LLC | Bodily fluid sample collection and transport |
US11247208B2 (en) | 2015-09-09 | 2022-02-15 | Labrador Diagnostics Llc | Methods and devices for sample collection and sample separation |
KR102521127B1 (ko) * | 2016-02-19 | 2023-04-13 | 퍼킨엘머 헬스 사이언시즈, 아이엔씨. | 미세유체 혼합 장치 및 방법 |
WO2017160840A1 (en) * | 2016-03-14 | 2017-09-21 | Diassess Inc. | Selectively vented biological assay devices and associated methods |
EP3493908B1 (de) * | 2016-08-05 | 2023-11-29 | Vital Signs Solutions Limited | Vorrichtung und verfahren zur flüssigkeitsanalyse zur detektion von biomarkern |
US11192102B2 (en) * | 2017-02-28 | 2021-12-07 | Lmsera Inc. | Microfluidic device |
US11857966B1 (en) | 2017-03-15 | 2024-01-02 | Labrador Diagnostics Llc | Methods and devices for sample collection and sample separation |
WO2018175169A1 (en) * | 2017-03-20 | 2018-09-27 | Wainamics, Inc. | Small volume self-metered blood separation device |
US11080848B2 (en) | 2017-04-06 | 2021-08-03 | Lucira Health, Inc. | Image-based disease diagnostics using a mobile device |
DE102017205978B4 (de) * | 2017-04-07 | 2021-11-04 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Mikrofluidisches System zur Kultivierung von oder der Analyse an lebenden Zellen oder Biomolekülen sowie ein Verfahren zu seiner Herstellung |
WO2019082902A1 (ja) * | 2017-10-23 | 2019-05-02 | 国立大学法人山梨大学 | 分注デバイス、それを用いた分注装置及び方法、並びに検査装置及び方法 |
USD878622S1 (en) * | 2018-04-07 | 2020-03-17 | Precision Nanosystems Inc. | Microfluidic chip |
US11925932B2 (en) | 2018-04-24 | 2024-03-12 | Hewlett-Packard Development Company, L.P. | Microfluidic devices |
WO2019209374A1 (en) | 2018-04-24 | 2019-10-31 | Hewlett-Packard Development Company, L.P. | Sequenced droplet ejection to deliver fluids |
WO2020018074A1 (en) | 2018-07-17 | 2020-01-23 | Hewlett-Packard Development Company, L.P. | Droplet ejectors to provide fluids to droplet ejectors |
DE102018206463A1 (de) * | 2018-04-26 | 2019-10-31 | Robert Bosch Gmbh | Verfahren zum Verdünnen, Mischen und/oder Aliquotieren von zwei Flüssigkeiten in einem mikrofluidisches System |
CN108855264A (zh) * | 2018-07-12 | 2018-11-23 | 北京乐普智慧医疗科技有限公司 | 一种多用途多指标微流控芯片 |
US11547993B2 (en) | 2018-07-17 | 2023-01-10 | Hewlett-Packard Development Company, L.P. | Droplet ejectors with target media |
CN110237763A (zh) * | 2019-05-15 | 2019-09-17 | 铜仁学院 | 一种基础医学实验用药剂混合制备装置 |
USD993443S1 (en) * | 2020-02-04 | 2023-07-25 | Ut-Battelle, Llc | Microfluidic glass chip interface bracket |
USD989342S1 (en) * | 2020-02-04 | 2023-06-13 | Ut-Battelle, Llc | Microfluidic polymer chip interface bracket |
WO2021252336A1 (en) * | 2020-06-09 | 2021-12-16 | Becton, Dickinson And Company | Biological fluid separation device |
CN111855993A (zh) * | 2020-07-21 | 2020-10-30 | 北京化工大学 | 一种基于声波微流体的高灵敏度快速免疫检测方法和应用 |
US11680875B2 (en) | 2020-12-16 | 2023-06-20 | International Business Machines Corporation | Microfluidic devices with capillary dilutors |
AT525192A1 (de) | 2021-06-15 | 2023-01-15 | Genspeed Biotech Gmbh | Mikrofluidischer chip |
EP4162875A1 (de) * | 2021-10-08 | 2023-04-12 | Homedicus GmbH | Mikrofluidische flüssigkeitsentnahmevorrichtung |
CN113952892B (zh) * | 2021-12-03 | 2023-10-10 | 花安堂生物科技集团有限公司 | 一种利用负压制备悬浮微液滴的方法 |
CN114324753A (zh) * | 2021-12-21 | 2022-04-12 | 广州万孚生物技术股份有限公司 | 试剂卡 |
Family Cites Families (63)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL89406C (de) | 1951-07-28 | |||
LU61733A1 (de) * | 1969-12-04 | 1971-01-18 | ||
US3640267A (en) | 1969-12-15 | 1972-02-08 | Damon Corp | Clinical sample container |
US3799742A (en) | 1971-12-20 | 1974-03-26 | C Coleman | Miniaturized integrated analytical test container |
US5128104A (en) | 1987-04-27 | 1992-07-07 | Murphy Harold R | Cuvette for automated testing machine |
US4952516A (en) | 1987-06-12 | 1990-08-28 | Pall Corporation | Self-venting diagnostic test device |
US5338689A (en) | 1987-08-24 | 1994-08-16 | Stiftung Fur Diagnostische Forschung | Method and card for detecting antigens and/or antibodies |
AU642444B2 (en) | 1989-11-30 | 1993-10-21 | Mochida Pharmaceutical Co., Ltd. | Reaction vessel |
JPH0417861A (ja) * | 1990-05-11 | 1992-01-22 | Ube Ind Ltd | 血漿採取装置 |
US5387526A (en) * | 1990-09-11 | 1995-02-07 | General Atomics | Coated capillary tube for the controlled release of reagent |
WO1993009668A1 (en) * | 1991-11-22 | 1993-05-27 | Affymax Technology N.V. | Combinatorial strategies for polymer synthesis |
US5478751A (en) | 1993-12-29 | 1995-12-26 | Abbott Laboratories | Self-venting immunodiagnositic devices and methods of performing assays |
US5728352A (en) * | 1994-11-14 | 1998-03-17 | Advanced Care Products | Disposable electronic diagnostic instrument |
US5731212A (en) * | 1994-12-20 | 1998-03-24 | International Technidyne Corporation | Test apparatus and method for testing cuvette accommodated samples |
CA2222126A1 (en) | 1995-06-16 | 1997-01-03 | Fred K. Forster | Microfabricated differential extraction device and method |
US5716852A (en) * | 1996-03-29 | 1998-02-10 | University Of Washington | Microfabricated diffusion-based chemical sensor |
US20020022261A1 (en) | 1995-06-29 | 2002-02-21 | Anderson Rolfe C. | Miniaturized genetic analysis systems and methods |
US5856174A (en) | 1995-06-29 | 1999-01-05 | Affymetrix, Inc. | Integrated nucleic acid diagnostic device |
US5863502A (en) | 1996-01-24 | 1999-01-26 | Sarnoff Corporation | Parallel reaction cassette and associated devices |
JP3213566B2 (ja) | 1996-04-26 | 2001-10-02 | アークレイ株式会社 | 検体分析用具およびそれを用いた検体分析方法並びに検体分析装置 |
US6001307A (en) | 1996-04-26 | 1999-12-14 | Kyoto Daiichi Kagaku Co., Ltd. | Device for analyzing a sample |
US5788927A (en) * | 1996-07-30 | 1998-08-04 | Bayer Corporation | Unified fluid circuit assembly for a clinical hematology instrument |
US6136272A (en) | 1997-09-26 | 2000-10-24 | University Of Washington | Device for rapidly joining and splitting fluid layers |
US5984129A (en) | 1997-12-29 | 1999-11-16 | Pasinski; Tom | Movable paint tray assembly for applying a liquid to a roller |
JP3654779B2 (ja) | 1998-01-06 | 2005-06-02 | 東京エレクトロン株式会社 | 基板洗浄具及び基板洗浄方法 |
WO1999060397A1 (en) * | 1998-05-18 | 1999-11-25 | University Of Washington | Liquid analysis cartridge |
US6451610B1 (en) * | 1999-04-14 | 2002-09-17 | International Technidyne Corporation | Method and apparatus for coagulation based assays |
JP4627395B2 (ja) * | 1999-08-11 | 2011-02-09 | 旭化成株式会社 | 分析用カートリッジ及び送液制御装置 |
US6752966B1 (en) * | 1999-09-10 | 2004-06-22 | Caliper Life Sciences, Inc. | Microfabrication methods and devices |
US6743399B1 (en) * | 1999-10-08 | 2004-06-01 | Micronics, Inc. | Pumpless microfluidics |
WO2001068238A2 (en) * | 2000-03-14 | 2001-09-20 | Micronics, Inc. | Microfluidic analysis cartridge |
CA2404008A1 (en) | 2000-03-31 | 2001-10-11 | Jurgen Sygusch | Protein crystallization in microfluidic structures |
US6431212B1 (en) * | 2000-05-24 | 2002-08-13 | Jon W. Hayenga | Valve for use in microfluidic structures |
US7351376B1 (en) * | 2000-06-05 | 2008-04-01 | California Institute Of Technology | Integrated active flux microfluidic devices and methods |
WO2002001081A2 (en) * | 2000-06-23 | 2002-01-03 | Micronics, Inc. | Valve for use in microfluidic structures |
JP3406281B2 (ja) | 2000-07-05 | 2003-05-12 | 清水製薬株式会社 | カテーテル |
WO2002030486A2 (en) * | 2000-10-13 | 2002-04-18 | Fluidigm Corporation | Microfluidic device based sample injection system for analytical devices |
US7378280B2 (en) * | 2000-11-16 | 2008-05-27 | California Institute Of Technology | Apparatus and methods for conducting assays and high throughput screening |
EP1488454B1 (de) * | 2001-02-16 | 2013-01-16 | Ignis Innovation Inc. | Pixeltreiberschaltung für eine organische leuchtdiode |
US20020159920A1 (en) * | 2001-04-03 | 2002-10-31 | Weigl Bernhard H. | Multiple redundant microfluidic structures cross reference to related applications |
US20020164816A1 (en) * | 2001-04-06 | 2002-11-07 | California Institute Of Technology | Microfluidic sample separation device |
US20020155010A1 (en) | 2001-04-24 | 2002-10-24 | Karp Christoph D. | Microfluidic valve with partially restrained element |
JP2002371955A (ja) * | 2001-06-15 | 2002-12-26 | Sanuki Kogyo Kk | 往復駆動装置及び該装置を使用した送液ポンプ |
WO2003007786A2 (en) | 2001-07-16 | 2003-01-30 | Depuy Products, Inc. | Porous delivery scaffold and method |
US7524462B2 (en) * | 2002-03-29 | 2009-04-28 | Agilent Technologies, Inc. | Capillary flow for a heterogenous assay in a micro-channel environment |
US7312085B2 (en) * | 2002-04-01 | 2007-12-25 | Fluidigm Corporation | Microfluidic particle-analysis systems |
TW590982B (en) * | 2002-09-27 | 2004-06-11 | Agnitio Science & Technology I | Micro-fluid driving device |
US7467928B2 (en) * | 2002-12-12 | 2008-12-23 | Board Of Trustees Of The University Of Arkansas | Microfluidic device utilizing magnetohydrodynamics and method for fabrication thereof |
US7419638B2 (en) | 2003-01-14 | 2008-09-02 | Micronics, Inc. | Microfluidic devices for fluid manipulation and analysis |
EP1587623A2 (de) | 2003-01-14 | 2005-10-26 | Micronics, Inc. | Mikrofluidische vorrichtung zur analyse und handhabung von flüssigkeiten |
US7416892B2 (en) * | 2003-01-21 | 2008-08-26 | Micronics, Inc. | Method and system for microfluidic manipulation, amplification and analysis of fluids, for example, bacteria assays and antiglobulin testing |
US7476363B2 (en) * | 2003-04-03 | 2009-01-13 | Fluidigm Corporation | Microfluidic devices and methods of using same |
AU2004228678A1 (en) * | 2003-04-03 | 2004-10-21 | Fluidigm Corp. | Microfluidic devices and methods of using same |
CN1767899A (zh) * | 2003-04-04 | 2006-05-03 | 皇家飞利浦电子股份有限公司 | 多微通道中的流体分隔 |
US7079092B2 (en) * | 2003-04-25 | 2006-07-18 | Barco Nv | Organic light-emitting diode (OLED) pre-charge circuit for use in a common anode large-screen display |
US20040224425A1 (en) * | 2003-05-08 | 2004-11-11 | Gjerde Douglas T. | Biomolecule open channel solid phase extraction systems and methods |
JP4168836B2 (ja) * | 2003-06-03 | 2008-10-22 | ソニー株式会社 | 表示装置 |
US7655470B2 (en) * | 2004-10-29 | 2010-02-02 | University Of Chicago | Method for manipulating a plurality of plugs and performing reactions therein in microfluidic systems |
WO2007005365A2 (en) * | 2005-06-29 | 2007-01-11 | Cascade Microtech, Inc. | A fluid dispensing system |
CA2518276A1 (en) * | 2005-09-13 | 2007-03-13 | Ignis Innovation Inc. | Compensation technique for luminance degradation in electro-luminance devices |
US7763453B2 (en) * | 2005-11-30 | 2010-07-27 | Micronics, Inc. | Microfluidic mixing and analytic apparatus |
US7976795B2 (en) * | 2006-01-19 | 2011-07-12 | Rheonix, Inc. | Microfluidic systems |
US20070280856A1 (en) * | 2006-06-02 | 2007-12-06 | Applera Corporation | Devices and Methods for Controlling Bubble Formation in Microfluidic Devices |
-
2004
- 2004-06-17 US US10/870,717 patent/US7419638B2/en active Active
-
2005
- 2005-06-15 EP EP05760971A patent/EP1773481B1/de active Active
- 2005-06-15 DE DE602005022878T patent/DE602005022878D1/de active Active
- 2005-06-15 WO PCT/US2005/021092 patent/WO2006009724A2/en active Application Filing
- 2005-06-15 JP JP2007516671A patent/JP4885852B2/ja active Active
- 2005-06-15 AT AT05760971T patent/ATE477049T1/de not_active IP Right Cessation
-
2008
- 2008-07-30 US US12/182,434 patent/US20090022624A1/en not_active Abandoned
-
2010
- 2010-01-11 US US12/685,582 patent/US8318109B2/en not_active Expired - Lifetime
-
2011
- 2011-09-02 US US13/225,280 patent/US8557198B2/en not_active Expired - Lifetime
-
2013
- 2013-09-06 US US14/020,670 patent/US8697009B2/en not_active Expired - Lifetime
-
2014
- 2014-02-14 US US14/181,485 patent/US20140370581A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1773481B1 (de) | 2010-08-11 |
US8697009B2 (en) | 2014-04-15 |
WO2006009724A2 (en) | 2006-01-26 |
JP2008503722A (ja) | 2008-02-07 |
US20140370581A1 (en) | 2014-12-18 |
ATE477049T1 (de) | 2010-08-15 |
US8318109B2 (en) | 2012-11-27 |
EP1773481A2 (de) | 2007-04-18 |
US20120064612A1 (en) | 2012-03-15 |
US20050106066A1 (en) | 2005-05-19 |
US7419638B2 (en) | 2008-09-02 |
US20140010736A1 (en) | 2014-01-09 |
JP4885852B2 (ja) | 2012-02-29 |
US20090022624A1 (en) | 2009-01-22 |
WO2006009724A3 (en) | 2006-05-04 |
US20100173395A1 (en) | 2010-07-08 |
US8557198B2 (en) | 2013-10-15 |
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