DE602004018390D1 - Proteinphosphorylierung in t-zellrezeptor-signalwegen - Google Patents
Proteinphosphorylierung in t-zellrezeptor-signalwegenInfo
- Publication number
- DE602004018390D1 DE602004018390D1 DE602004018390T DE602004018390T DE602004018390D1 DE 602004018390 D1 DE602004018390 D1 DE 602004018390D1 DE 602004018390 T DE602004018390 T DE 602004018390T DE 602004018390 T DE602004018390 T DE 602004018390T DE 602004018390 D1 DE602004018390 D1 DE 602004018390D1
- Authority
- DE
- Germany
- Prior art keywords
- modified peptide
- specific antibody
- modification
- preparation
- modified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/25—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving enzymes not classifiable in groups C12Q1/26 - C12Q1/66
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Computational Biology (AREA)
- General Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/777,893 US7300753B2 (en) | 1998-09-04 | 2004-02-12 | Immunoaffinity isolation of modified peptides from complex mixtures |
PCT/US2004/032511 WO2005083444A1 (en) | 2004-02-12 | 2004-10-04 | Protein phosphorylation in t-cell receptor signaling pathways |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602004018390D1 true DE602004018390D1 (de) | 2009-01-22 |
Family
ID=34911345
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004018388T Expired - Fee Related DE602004018388D1 (de) | 2004-02-12 | 2004-07-07 | Proteinphosphorylierung bei grosszellig-anaplastischem lymphom |
DE602004018836T Expired - Fee Related DE602004018836D1 (de) | 2004-02-12 | 2004-08-12 | Proteinphosphorylierung in c-src-signalwegen |
DE602004018390T Expired - Fee Related DE602004018390D1 (de) | 2004-02-12 | 2004-10-04 | Proteinphosphorylierung in t-zellrezeptor-signalwegen |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004018388T Expired - Fee Related DE602004018388D1 (de) | 2004-02-12 | 2004-07-07 | Proteinphosphorylierung bei grosszellig-anaplastischem lymphom |
DE602004018836T Expired - Fee Related DE602004018836D1 (de) | 2004-02-12 | 2004-08-12 | Proteinphosphorylierung in c-src-signalwegen |
Country Status (8)
Country | Link |
---|---|
US (1) | US7300753B2 (de) |
EP (3) | EP1718976B1 (de) |
JP (2) | JP2005225858A (de) |
AT (3) | ATE417273T1 (de) |
CA (3) | CA2556021A1 (de) |
DE (3) | DE602004018388D1 (de) |
ES (3) | ES2317044T3 (de) |
WO (3) | WO2005083439A1 (de) |
Families Citing this family (61)
Publication number | Priority date | Publication date | Assignee | Title |
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US9085609B2 (en) * | 1998-09-04 | 2015-07-21 | Cell Signaling Technology, Inc. | Production of motif-specific and context-independent antibodies using peptide libraries as antigens |
US20120244594A9 (en) * | 1998-09-04 | 2012-09-27 | Cell Signaling Technology, Inc. | Immunoaffinity isolation of modified peptides from complex mixtures |
US20110111424A1 (en) * | 2001-06-21 | 2011-05-12 | Cell Signaling Technology, Inc. | Analysis of ubiquitinated polypeptides |
US7381535B2 (en) | 2002-07-10 | 2008-06-03 | The Board Of Trustees Of The Leland Stanford Junior | Methods and compositions for detecting receptor-ligand interactions in single cells |
US7563584B2 (en) | 2001-07-10 | 2009-07-21 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for detecting the activation state of multiple proteins in single cells |
US7393656B2 (en) * | 2001-07-10 | 2008-07-01 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for risk stratification |
US7973134B2 (en) * | 2004-07-07 | 2011-07-05 | Cell Signaling Technology, Inc. | Reagents for the detection of protein phosphorylation in anaplastic large cell lymphoma signaling pathways |
US7935790B2 (en) * | 2004-10-04 | 2011-05-03 | Cell Singaling Technology, Inc. | Reagents for the detection of protein phosphorylation in T-cell receptor signaling pathways |
US7807789B2 (en) * | 2004-12-21 | 2010-10-05 | Cell Signaling Technology, Inc. | Reagents for the detection of protein phosphorylation in EGFR-signaling pathways |
CA2596518A1 (en) * | 2005-01-31 | 2006-08-10 | Insilicos, Llc | Methods of identification of biomarkers with mass spectrometry techniques |
US20090099340A1 (en) * | 2007-10-12 | 2009-04-16 | Cell Signaling Technology, Inc. | Reagents for the detection of protein phosphorylation in carcinoma signaling pathways |
WO2006134056A1 (en) * | 2005-06-14 | 2006-12-21 | Cellzome Ag | Process for the identification of novel enzyme interacting compounds |
US7815418B2 (en) | 2005-08-03 | 2010-10-19 | Mitsubishi Heavy Industries, Ltd. | Shroud and rotary vane wheel of propeller fan and propeller fan |
WO2007027906A2 (en) * | 2005-08-31 | 2007-03-08 | Cell Signaling Technology, Inc. | Reagents for the detection of protein phosphorylation in leukemia signaling pathways |
EP1929305A2 (de) * | 2005-08-31 | 2008-06-11 | Cell Signaling Technology, Inc. | Reagentien zum nachweis der proteinphosphorylierung in leukämie-signalwegen |
US20100151495A9 (en) * | 2005-08-31 | 2010-06-17 | Cell Signaling Technolgy, Inc. | Reagents for the detection of protein phosphorylation in carcinoma signaling pathways |
CN101321782A (zh) * | 2005-12-01 | 2008-12-10 | 纽约血库公司 | Abl激酶的肽抑制剂 |
US20120208824A1 (en) | 2006-01-20 | 2012-08-16 | Cell Signaling Technology, Inc. | ROS Kinase in Lung Cancer |
US8168383B2 (en) | 2006-04-14 | 2012-05-01 | Cell Signaling Technology, Inc. | Gene defects and mutant ALK kinase in human solid tumors |
CA2982018C (en) * | 2006-04-14 | 2023-10-17 | Cell Signaling Technology, Inc. | Gene defects and mutant alk kinase in human solid tumors |
DK2450437T3 (en) | 2006-04-14 | 2017-09-11 | Cell Signaling Technology Inc | Gene defects and mutant ALK kinase in human solid tumors |
WO2007127335A2 (en) * | 2006-04-27 | 2007-11-08 | Cell Signaling Technology, Inc. | Reagents for the detection of protein phosphorylation in atm and atr kinase signaling pathways |
WO2007133688A2 (en) * | 2006-05-12 | 2007-11-22 | Cell Signaling Technology, Inc. | Reagents for the detection of tyrosine phosphorylation in brain ischemia signaling pathways |
US20150232540A1 (en) | 2006-07-11 | 2015-08-20 | Cell Signaling Technology, Inc. | Analysis of ubiquitnated polypeptides |
US20100151483A1 (en) * | 2006-07-13 | 2010-06-17 | Cell Signaling Technology, Inc. | Reagents for the detection of protein phosphorylation in signaling pathways |
WO2008009004A2 (en) * | 2006-07-13 | 2008-01-17 | Cell Signaling Technology, Inc. | Reagents for the detection of protein phosphorylation in signaling pathways |
WO2008013948A2 (en) * | 2006-07-27 | 2008-01-31 | Cell Signaling Technology, Inc. | Tyrosine phosphorylation sites |
US7939636B2 (en) * | 2006-08-11 | 2011-05-10 | Cell Signaling Technology, Inc. | Reagents for the detection of protein phosphorylation in c-Src signaling pathways |
US20090258442A1 (en) * | 2006-08-31 | 2009-10-15 | Cell Signaling Technology, Inc. | Reagents for the detection of protein phosphorylation in carcinoma signaling pathways |
MX2009002576A (es) * | 2006-09-08 | 2009-03-20 | Wyeth Corp | Lavado de arginina en purificacion de proteina utilizando cromatografia de afinidad. |
WO2008079407A1 (en) * | 2006-12-26 | 2008-07-03 | Brigham Young University | Serum proteomics system and associated methods |
EP1975184A3 (de) * | 2007-03-26 | 2008-11-26 | Cell Signaling Technology, Inc. | Serin- oder Threonin-Phosphorylationsorte |
US20080238709A1 (en) * | 2007-03-28 | 2008-10-02 | Faramarz Vaziri | One-way communication apparatus with dynamic key generation |
US7977462B2 (en) | 2007-04-19 | 2011-07-12 | Cell Signaling Technology, Inc. | Tyrosine phosphorylation sites |
EP2160752A4 (de) * | 2007-05-23 | 2012-11-07 | Nicholas A Williamson | Verfahren zur massenanalyse von zielmolekülen in komplexen mischungen |
US20090220991A1 (en) * | 2008-02-29 | 2009-09-03 | Cell Signaling Technology, Inc. | Reagents for the detection of protein phosphorylation in leukemia signaling pathways |
EP2124060A1 (de) * | 2008-05-23 | 2009-11-25 | ETH Zurich | Verfahren zur Assayerzeugung von Peptiden/Proteinen mit hohem Durchsatz und so erzeugte Assays |
JP2009288160A (ja) * | 2008-05-30 | 2009-12-10 | Hitachi High-Technologies Corp | 生体試料解析システム、生体試料解析手法、生体試料前処理装置及び生体試料前処理方法 |
US7834313B2 (en) | 2008-08-08 | 2010-11-16 | Quest Diagnostics Investments Incorporated | Mass spectrometry assay for plasma-renin |
US8106351B2 (en) | 2008-08-08 | 2012-01-31 | Quest Diagnostics Investments Incorporated | Mass spectrometry assay for plasma-renin |
WO2010040024A2 (en) * | 2008-10-03 | 2010-04-08 | President And Fellows Of Harvard College | Methods, compositions and kits for high throughput kinase activity screening using mass spectrometry and stable isotopes |
US8907059B2 (en) * | 2008-11-14 | 2014-12-09 | Bio-Rad Laboratories, Inc. | Phosphopeptide enrichment of compositions by fractionation on ceramic hydroxyapatite |
US9453845B2 (en) | 2010-02-01 | 2016-09-27 | Cell Signaling Technology, Inc. | Mass spectroscopy analysis of mutant polypeptides in biological samples |
JP5356282B2 (ja) * | 2010-02-26 | 2013-12-04 | 大学共同利用機関法人自然科学研究機構 | 受容体型チロシンホスファターゼPtprzの活性測定用試薬及びその用途 |
WO2012019132A2 (en) | 2010-08-06 | 2012-02-09 | Cell Signaling Technology, Inc. | Anaplastic lymphoma kinase in kidney cancer |
US9249231B2 (en) | 2010-11-05 | 2016-02-02 | Cell Signaling Technology, Inc. | Motif-specific and context-independent antibodies that specifically bind to a cleaved caspase motif |
JPWO2012111249A1 (ja) * | 2011-02-14 | 2014-07-03 | 学校法人麻布獣医学園 | 質量分析法における質量変化を検出する方法及び安定同位体標識タンパク質の絶対量の定量方法 |
CN108220297A (zh) | 2011-03-09 | 2018-06-29 | 细胞信号科技公司 | 用于生成单克隆抗体的方法和试剂 |
EP2573565A1 (de) | 2011-09-23 | 2013-03-27 | Gerhard Matthias Kresbach | Immunnachweisverfahren für gemeinsame Epitope von zwei oder mehr Analyten in Proben mit komplexen Zusammensetzungen, Vorrichtung und Kit zum Ermöglichen dieses Immunnachweisverfahrens |
EP2766723A4 (de) * | 2011-10-12 | 2015-06-10 | Univ North Carolina | Multiplexierte kinasehemmerkügelchen und ihre verwendung |
CA2868632C (en) * | 2012-05-09 | 2021-03-30 | Dalhousie University | Filtration and extraction assembly |
CN103421792B (zh) * | 2013-06-21 | 2015-03-25 | 浙江理工大学 | 真核生物翻译起始因子4H(eIF4H)基因沉默抑制肿瘤细胞生长的方法及其应用 |
WO2015120036A1 (en) * | 2014-02-04 | 2015-08-13 | University Of Virginia Patent Foundation | Compositions and methods for analysis of protein sequences and post-translational modifications |
US20170168055A1 (en) * | 2015-12-11 | 2017-06-15 | Expression Pathology, Inc. | SRM/MRM Assays |
US10927400B2 (en) * | 2016-11-09 | 2021-02-23 | Kendrick Laboratories, Inc. | Protein standard compositions and methods of making and using the same |
WO2019183334A1 (en) | 2018-03-21 | 2019-09-26 | Waters Technologies Corporation | Non-antibody high-affinity-based sample preparation, sorbents, devices and methods |
CN112585470A (zh) * | 2018-06-21 | 2021-03-30 | 乌得勒支大学控股有限责任公司 | 用于监测样品中激酶活性的方法 |
CN112812187B (zh) * | 2021-01-18 | 2021-12-17 | 南昌大学第一附属医院 | 一种磷酸化eif5b特异性抗体及其制备方法与应用 |
CN114605497B (zh) * | 2021-02-10 | 2023-04-28 | 北京欣安诚科技有限公司 | 一种dapk1磷酸化底物的人工小分子干扰肽及其制药用途 |
CN113061593B (zh) * | 2021-04-02 | 2023-11-10 | 洛阳华荣生物技术有限公司 | 一种l-苹果酸脱氢酶突变体及其应用 |
CN113312056B (zh) * | 2021-06-16 | 2022-04-19 | 浪潮云信息技术股份公司 | angular大型集成项目的国际化实现方法、电子设备及存储介质 |
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US5962224A (en) | 1995-12-19 | 1999-10-05 | Dana-Farber Cancer Institute | Isolated DNA encoding p62 polypeptides and uses therefor |
US5885841A (en) | 1996-09-11 | 1999-03-23 | Eli Lilly And Company | System and methods for qualitatively and quantitatively comparing complex admixtures using single ion chromatograms derived from spectroscopic analysis of such admixtures |
US6207370B1 (en) * | 1997-09-02 | 2001-03-27 | Sequenom, Inc. | Diagnostics based on mass spectrometric detection of translated target polypeptides |
US5965352A (en) * | 1998-05-08 | 1999-10-12 | Rosetta Inpharmatics, Inc. | Methods for identifying pathways of drug action |
CA2243230A1 (en) | 1998-07-15 | 2000-01-15 | Aled Edwards | A device and method for the determination of protein domain boundaries |
US7198896B2 (en) * | 1998-09-04 | 2007-04-03 | Cell Signaling Technology, Inc. | Immunoaffinity isolation of modified peptides from complex mixtures |
US6441140B1 (en) | 1998-09-04 | 2002-08-27 | Cell Signaling Technology, Inc. | Production of motif-specific and context-independent antibodies using peptide libraries as antigens |
US6379970B1 (en) | 1999-04-30 | 2002-04-30 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Analysis of differential protein expression |
WO2000070344A2 (en) * | 1999-05-13 | 2000-11-23 | Admetric Biochem Inc. | Method for increasing the efficiency of experimental fractionation in activity profiling of compound mixtures |
US6818454B2 (en) * | 2001-02-16 | 2004-11-16 | Battelle Memorial Institute | Phosphoprotein binding agents and methods of their use |
WO2003016861A2 (en) * | 2001-08-14 | 2003-02-27 | President And Fellows Of Harvard College | Absolute quantification of proteins and modified forms thereof by multistage mass spectrometry |
-
2004
- 2004-02-12 US US10/777,893 patent/US7300753B2/en not_active Expired - Fee Related
- 2004-07-07 CA CA002556021A patent/CA2556021A1/en not_active Abandoned
- 2004-07-07 EP EP04777654A patent/EP1718976B1/de not_active Expired - Lifetime
- 2004-07-07 DE DE602004018388T patent/DE602004018388D1/de not_active Expired - Fee Related
- 2004-07-07 WO PCT/US2004/021670 patent/WO2005083439A1/en active Application Filing
- 2004-07-07 ES ES04777654T patent/ES2317044T3/es not_active Expired - Lifetime
- 2004-07-07 AT AT04777654T patent/ATE417273T1/de not_active IP Right Cessation
- 2004-08-12 WO PCT/US2004/026199 patent/WO2005083113A1/en active Application Filing
- 2004-08-12 EP EP04780956A patent/EP1718760B1/de not_active Not-in-force
- 2004-08-12 DE DE602004018836T patent/DE602004018836D1/de not_active Expired - Fee Related
- 2004-08-12 AT AT04780956T patent/ATE419379T1/de not_active IP Right Cessation
- 2004-08-12 CA CA002556019A patent/CA2556019A1/en not_active Abandoned
- 2004-08-12 ES ES04780956T patent/ES2321197T3/es active Active
- 2004-09-07 JP JP2004259574A patent/JP2005225858A/ja active Pending
- 2004-10-04 DE DE602004018390T patent/DE602004018390D1/de not_active Expired - Fee Related
- 2004-10-04 AT AT04794025T patent/ATE417276T1/de not_active IP Right Cessation
- 2004-10-04 WO PCT/US2004/032511 patent/WO2005083444A1/en active Application Filing
- 2004-10-04 EP EP04794025A patent/EP1718977B1/de not_active Not-in-force
- 2004-10-04 ES ES04794025T patent/ES2321520T3/es active Active
- 2004-10-04 CA CA002556022A patent/CA2556022A1/en not_active Abandoned
-
2007
- 2007-06-27 JP JP2007169161A patent/JP2007308506A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
CA2556021A1 (en) | 2005-09-09 |
JP2005225858A (ja) | 2005-08-25 |
ES2317044T3 (es) | 2009-04-16 |
US20050003450A1 (en) | 2005-01-06 |
EP1718976B1 (de) | 2008-12-10 |
ES2321520T3 (es) | 2009-06-08 |
DE602004018836D1 (de) | 2009-02-12 |
ATE419379T1 (de) | 2009-01-15 |
WO2005083439A1 (en) | 2005-09-09 |
ATE417273T1 (de) | 2008-12-15 |
EP1718760B1 (de) | 2008-12-31 |
JP2007308506A (ja) | 2007-11-29 |
CA2556022A1 (en) | 2005-09-09 |
EP1718977A1 (de) | 2006-11-08 |
ES2321197T3 (es) | 2009-06-03 |
WO2005083444A1 (en) | 2005-09-09 |
WO2005083113A1 (en) | 2005-09-09 |
ATE417276T1 (de) | 2008-12-15 |
EP1718977B1 (de) | 2008-12-10 |
EP1718976A1 (de) | 2006-11-08 |
DE602004018388D1 (de) | 2009-01-22 |
EP1718760A1 (de) | 2006-11-08 |
US7300753B2 (en) | 2007-11-27 |
CA2556019A1 (en) | 2005-09-09 |
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