ATE419379T1 - Proteinphosphorylierung in c-src-signalwegen - Google Patents

Proteinphosphorylierung in c-src-signalwegen

Info

Publication number
ATE419379T1
ATE419379T1 AT04780956T AT04780956T ATE419379T1 AT E419379 T1 ATE419379 T1 AT E419379T1 AT 04780956 T AT04780956 T AT 04780956T AT 04780956 T AT04780956 T AT 04780956T AT E419379 T1 ATE419379 T1 AT E419379T1
Authority
AT
Austria
Prior art keywords
modified peptide
specific antibody
modification
preparation
modified
Prior art date
Application number
AT04780956T
Other languages
English (en)
Inventor
Albrecht Moritz
Kimberly Lee
John Rush
Roberto Polakiewicz
Original Assignee
Cell Signaling Technology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cell Signaling Technology Inc filed Critical Cell Signaling Technology Inc
Application granted granted Critical
Publication of ATE419379T1 publication Critical patent/ATE419379T1/de

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/25Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving enzymes not classifiable in groups C12Q1/26 - C12Q1/66
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT04780956T 2004-02-12 2004-08-12 Proteinphosphorylierung in c-src-signalwegen ATE419379T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/777,893 US7300753B2 (en) 1998-09-04 2004-02-12 Immunoaffinity isolation of modified peptides from complex mixtures

Publications (1)

Publication Number Publication Date
ATE419379T1 true ATE419379T1 (de) 2009-01-15

Family

ID=34911345

Family Applications (3)

Application Number Title Priority Date Filing Date
AT04777654T ATE417273T1 (de) 2004-02-12 2004-07-07 Proteinphosphorylierung bei grosszellig- anaplastischem lymphom
AT04780956T ATE419379T1 (de) 2004-02-12 2004-08-12 Proteinphosphorylierung in c-src-signalwegen
AT04794025T ATE417276T1 (de) 2004-02-12 2004-10-04 Proteinphosphorylierung in t-zellrezeptor- signalwegen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT04777654T ATE417273T1 (de) 2004-02-12 2004-07-07 Proteinphosphorylierung bei grosszellig- anaplastischem lymphom

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT04794025T ATE417276T1 (de) 2004-02-12 2004-10-04 Proteinphosphorylierung in t-zellrezeptor- signalwegen

Country Status (8)

Country Link
US (1) US7300753B2 (de)
EP (3) EP1718976B1 (de)
JP (2) JP2005225858A (de)
AT (3) ATE417273T1 (de)
CA (3) CA2556021A1 (de)
DE (3) DE602004018388D1 (de)
ES (3) ES2317044T3 (de)
WO (3) WO2005083439A1 (de)

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US20110111424A1 (en) * 2001-06-21 2011-05-12 Cell Signaling Technology, Inc. Analysis of ubiquitinated polypeptides
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US7381535B2 (en) 2002-07-10 2008-06-03 The Board Of Trustees Of The Leland Stanford Junior Methods and compositions for detecting receptor-ligand interactions in single cells
US7393656B2 (en) * 2001-07-10 2008-07-01 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for risk stratification
US7973134B2 (en) * 2004-07-07 2011-07-05 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in anaplastic large cell lymphoma signaling pathways
US7935790B2 (en) * 2004-10-04 2011-05-03 Cell Singaling Technology, Inc. Reagents for the detection of protein phosphorylation in T-cell receptor signaling pathways
US7807789B2 (en) * 2004-12-21 2010-10-05 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in EGFR-signaling pathways
EP1844322A4 (de) * 2005-01-31 2009-06-10 Insilicos Llc Verfahren zur identifikation von biomarkern mittels techniken der massenspektrometrie
US20090099340A1 (en) * 2007-10-12 2009-04-16 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
PL1891446T3 (pl) * 2005-06-14 2013-08-30 Cellzome Gmbh Sposób identyfikacji nowych związków oddziałujących z enzymami
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US20100151495A9 (en) * 2005-08-31 2010-06-17 Cell Signaling Technolgy, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
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WO2007027957A2 (en) * 2005-08-31 2007-03-08 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in leukemia signaling pathways
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DK2016089T3 (da) * 2006-04-14 2014-04-22 Cell Signaling Technology Inc Gendefekter og mutant-alk-kinase i humane faste tumorer
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US20090298093A1 (en) * 2006-04-27 2009-12-03 Roberto Polakiewicz Reagents for the Detection of Protein Phosphorylation in ATM & ATR Kinase Signaling Pathways
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US7939636B2 (en) * 2006-08-11 2011-05-10 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in c-Src signaling pathways
US20090258442A1 (en) * 2006-08-31 2009-10-15 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
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JP5194212B2 (ja) * 2006-12-26 2013-05-08 ブリガム・ヤング・ユニバーシティ 血清プロテオミクスシステムと関連する方法
EP1975184A3 (de) * 2007-03-26 2008-11-26 Cell Signaling Technology, Inc. Serin- oder Threonin-Phosphorylationsorte
US20080238709A1 (en) * 2007-03-28 2008-10-02 Faramarz Vaziri One-way communication apparatus with dynamic key generation
US7977462B2 (en) 2007-04-19 2011-07-12 Cell Signaling Technology, Inc. Tyrosine phosphorylation sites
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Also Published As

Publication number Publication date
EP1718976B1 (de) 2008-12-10
WO2005083444A1 (en) 2005-09-09
JP2005225858A (ja) 2005-08-25
EP1718976A1 (de) 2006-11-08
CA2556021A1 (en) 2005-09-09
CA2556019A1 (en) 2005-09-09
ATE417273T1 (de) 2008-12-15
CA2556022A1 (en) 2005-09-09
DE602004018390D1 (de) 2009-01-22
ES2317044T3 (es) 2009-04-16
EP1718760B1 (de) 2008-12-31
WO2005083113A1 (en) 2005-09-09
ES2321197T3 (es) 2009-06-03
EP1718977A1 (de) 2006-11-08
ES2321520T3 (es) 2009-06-08
EP1718977B1 (de) 2008-12-10
DE602004018836D1 (de) 2009-02-12
JP2007308506A (ja) 2007-11-29
EP1718760A1 (de) 2006-11-08
WO2005083439A1 (en) 2005-09-09
US7300753B2 (en) 2007-11-27
US20050003450A1 (en) 2005-01-06
DE602004018388D1 (de) 2009-01-22
ATE417276T1 (de) 2008-12-15

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