DE602004018388D1 - Proteinphosphorylierung bei grosszellig-anaplastischem lymphom - Google Patents

Proteinphosphorylierung bei grosszellig-anaplastischem lymphom

Info

Publication number
DE602004018388D1
DE602004018388D1 DE602004018388T DE602004018388T DE602004018388D1 DE 602004018388 D1 DE602004018388 D1 DE 602004018388D1 DE 602004018388 T DE602004018388 T DE 602004018388T DE 602004018388 T DE602004018388 T DE 602004018388T DE 602004018388 D1 DE602004018388 D1 DE 602004018388D1
Authority
DE
Germany
Prior art keywords
modified peptide
specific antibody
modification
preparation
modified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE602004018388T
Other languages
English (en)
Inventor
Albrecht Moritz
Kimberly Lee
John Rush
Roberto Polakiewicz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cell Signaling Technology Inc
Original Assignee
Cell Signaling Technology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cell Signaling Technology Inc filed Critical Cell Signaling Technology Inc
Publication of DE602004018388D1 publication Critical patent/DE602004018388D1/de
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/25—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving enzymes not classifiable in groups C12Q1/26 - C12Q1/66
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE602004018388T 2004-02-12 2004-07-07 Proteinphosphorylierung bei grosszellig-anaplastischem lymphom Expired - Fee Related DE602004018388D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/777,893 US7300753B2 (en) 1998-09-04 2004-02-12 Immunoaffinity isolation of modified peptides from complex mixtures
PCT/US2004/021670 WO2005083439A1 (en) 2004-02-12 2004-07-07 Protein phosphorylation in anaplastic large cell lymphoma

Publications (1)

Publication Number Publication Date
DE602004018388D1 true DE602004018388D1 (de) 2009-01-22

Family

ID=34911345

Family Applications (3)

Application Number Title Priority Date Filing Date
DE602004018388T Expired - Fee Related DE602004018388D1 (de) 2004-02-12 2004-07-07 Proteinphosphorylierung bei grosszellig-anaplastischem lymphom
DE602004018836T Expired - Fee Related DE602004018836D1 (de) 2004-02-12 2004-08-12 Proteinphosphorylierung in c-src-signalwegen
DE602004018390T Expired - Fee Related DE602004018390D1 (de) 2004-02-12 2004-10-04 Proteinphosphorylierung in t-zellrezeptor-signalwegen

Family Applications After (2)

Application Number Title Priority Date Filing Date
DE602004018836T Expired - Fee Related DE602004018836D1 (de) 2004-02-12 2004-08-12 Proteinphosphorylierung in c-src-signalwegen
DE602004018390T Expired - Fee Related DE602004018390D1 (de) 2004-02-12 2004-10-04 Proteinphosphorylierung in t-zellrezeptor-signalwegen

Country Status (8)

Country Link
US (1) US7300753B2 (de)
EP (3) EP1718976B1 (de)
JP (2) JP2005225858A (de)
AT (3) ATE417273T1 (de)
CA (3) CA2556021A1 (de)
DE (3) DE602004018388D1 (de)
ES (3) ES2317044T3 (de)
WO (3) WO2005083439A1 (de)

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US20110111424A1 (en) * 2001-06-21 2011-05-12 Cell Signaling Technology, Inc. Analysis of ubiquitinated polypeptides
WO2003067210A2 (en) 2001-07-10 2003-08-14 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for detecting the activation state of the multiple proteins in single cells
US7381535B2 (en) 2002-07-10 2008-06-03 The Board Of Trustees Of The Leland Stanford Junior Methods and compositions for detecting receptor-ligand interactions in single cells
US7393656B2 (en) * 2001-07-10 2008-07-01 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for risk stratification
US7973134B2 (en) * 2004-07-07 2011-07-05 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in anaplastic large cell lymphoma signaling pathways
US7935790B2 (en) * 2004-10-04 2011-05-03 Cell Singaling Technology, Inc. Reagents for the detection of protein phosphorylation in T-cell receptor signaling pathways
US7807789B2 (en) * 2004-12-21 2010-10-05 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in EGFR-signaling pathways
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US20090099340A1 (en) * 2007-10-12 2009-04-16 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
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EP1934867A2 (de) * 2005-08-31 2008-06-25 Cell Signaling Technology, Inc. Reagentien zum nachweis der proteinphosphorylierung in leukämie-signalwegen
EP1929305A2 (de) * 2005-08-31 2008-06-11 Cell Signaling Technology, Inc. Reagentien zum nachweis der proteinphosphorylierung in leukämie-signalwegen
US20100151495A9 (en) * 2005-08-31 2010-06-17 Cell Signaling Technolgy, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
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US8168383B2 (en) 2006-04-14 2012-05-01 Cell Signaling Technology, Inc. Gene defects and mutant ALK kinase in human solid tumors
US20090298093A1 (en) * 2006-04-27 2009-12-03 Roberto Polakiewicz Reagents for the Detection of Protein Phosphorylation in ATM & ATR Kinase Signaling Pathways
US20090203034A1 (en) * 2006-05-12 2009-08-13 Ailan Guo Reagents for the detection of tyrosine phosphorylation in brain ischemia signaling pathways
US20150232540A1 (en) 2006-07-11 2015-08-20 Cell Signaling Technology, Inc. Analysis of ubiquitnated polypeptides
WO2008009004A2 (en) * 2006-07-13 2008-01-17 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in signaling pathways
US20100151483A1 (en) * 2006-07-13 2010-06-17 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in signaling pathways
WO2008013954A2 (en) * 2006-07-27 2008-01-31 Cell Signaling Technology, Inc. Tyrosine phosphorylation sites
US7939636B2 (en) * 2006-08-11 2011-05-10 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in c-Src signaling pathways
US20090258442A1 (en) * 2006-08-31 2009-10-15 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in carcinoma signaling pathways
MX2009002576A (es) * 2006-09-08 2009-03-20 Wyeth Corp Lavado de arginina en purificacion de proteina utilizando cromatografia de afinidad.
WO2008079407A1 (en) * 2006-12-26 2008-07-03 Brigham Young University Serum proteomics system and associated methods
EP1975184A3 (de) * 2007-03-26 2008-11-26 Cell Signaling Technology, Inc. Serin- oder Threonin-Phosphorylationsorte
US20080238709A1 (en) * 2007-03-28 2008-10-02 Faramarz Vaziri One-way communication apparatus with dynamic key generation
US7977462B2 (en) 2007-04-19 2011-07-12 Cell Signaling Technology, Inc. Tyrosine phosphorylation sites
US20100311176A1 (en) * 2007-05-23 2010-12-09 Applied Biosystems, Llc Method of mass analysis of target molecules in complex mixtures
US20090220991A1 (en) * 2008-02-29 2009-09-03 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in leukemia signaling pathways
EP2124060A1 (de) * 2008-05-23 2009-11-25 ETH Zurich Verfahren zur Assayerzeugung von Peptiden/Proteinen mit hohem Durchsatz und so erzeugte Assays
JP2009288160A (ja) * 2008-05-30 2009-12-10 Hitachi High-Technologies Corp 生体試料解析システム、生体試料解析手法、生体試料前処理装置及び生体試料前処理方法
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CN112585470A (zh) * 2018-06-21 2021-03-30 乌得勒支大学控股有限责任公司 用于监测样品中激酶活性的方法
CN112812187B (zh) * 2021-01-18 2021-12-17 南昌大学第一附属医院 一种磷酸化eif5b特异性抗体及其制备方法与应用
CN114605497B (zh) * 2021-02-10 2023-04-28 北京欣安诚科技有限公司 一种dapk1磷酸化底物的人工小分子干扰肽及其制药用途
CN113061593B (zh) * 2021-04-02 2023-11-10 洛阳华荣生物技术有限公司 一种l-苹果酸脱氢酶突变体及其应用
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Also Published As

Publication number Publication date
ES2317044T3 (es) 2009-04-16
EP1718760B1 (de) 2008-12-31
JP2005225858A (ja) 2005-08-25
ATE417276T1 (de) 2008-12-15
JP2007308506A (ja) 2007-11-29
CA2556019A1 (en) 2005-09-09
EP1718976B1 (de) 2008-12-10
DE602004018836D1 (de) 2009-02-12
WO2005083439A1 (en) 2005-09-09
CA2556021A1 (en) 2005-09-09
ATE419379T1 (de) 2009-01-15
ATE417273T1 (de) 2008-12-15
WO2005083113A1 (en) 2005-09-09
US20050003450A1 (en) 2005-01-06
EP1718977A1 (de) 2006-11-08
EP1718976A1 (de) 2006-11-08
WO2005083444A1 (en) 2005-09-09
EP1718977B1 (de) 2008-12-10
ES2321197T3 (es) 2009-06-03
US7300753B2 (en) 2007-11-27
EP1718760A1 (de) 2006-11-08
ES2321520T3 (es) 2009-06-08
CA2556022A1 (en) 2005-09-09
DE602004018390D1 (de) 2009-01-22

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