DE60122685D1 - Induziertes genexpressionssystem basierend auf ecdysonrezeptoren - Google Patents

Induziertes genexpressionssystem basierend auf ecdysonrezeptoren

Info

Publication number
DE60122685D1
DE60122685D1 DE60122685T DE60122685T DE60122685D1 DE 60122685 D1 DE60122685 D1 DE 60122685D1 DE 60122685 T DE60122685 T DE 60122685T DE 60122685 T DE60122685 T DE 60122685T DE 60122685 D1 DE60122685 D1 DE 60122685D1
Authority
DE
Germany
Prior art keywords
ecdyson
receptors
gene expression
system based
expression system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60122685T
Other languages
English (en)
Other versions
DE60122685T2 (de
Inventor
Reddy Palli
Marianna Zinovjevna Kapitskaya
Ervin Cress
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Precigen Inc
Original Assignee
Rheogene Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rheogene Inc filed Critical Rheogene Inc
Application granted granted Critical
Publication of DE60122685D1 publication Critical patent/DE60122685D1/de
Publication of DE60122685T2 publication Critical patent/DE60122685T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1055—Protein x Protein interaction, e.g. two hybrid selection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70567—Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Endocrinology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60122685T 2000-03-22 2001-03-21 Induziertes genexpressionssystem basierend auf ecdysonrezeptoren Expired - Lifetime DE60122685T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US19135500P 2000-03-22 2000-03-22
US191355P 2000-03-22
US26979901P 2001-02-20 2001-02-20
US269799P 2001-02-20
PCT/US2001/009050 WO2001070816A2 (en) 2000-03-22 2001-03-21 Ecdysone receptor-based inducible gene expression system

Publications (2)

Publication Number Publication Date
DE60122685D1 true DE60122685D1 (de) 2006-10-12
DE60122685T2 DE60122685T2 (de) 2007-08-23

Family

ID=26886975

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60122685T Expired - Lifetime DE60122685T2 (de) 2000-03-22 2001-03-21 Induziertes genexpressionssystem basierend auf ecdysonrezeptoren

Country Status (11)

Country Link
US (1) US7091038B2 (de)
EP (1) EP1266015B1 (de)
JP (1) JP5031967B2 (de)
CN (1) CN1304578C (de)
AR (1) AR028276A1 (de)
AT (1) ATE338135T1 (de)
AU (2) AU2001249315A1 (de)
CA (1) CA2404253C (de)
DE (1) DE60122685T2 (de)
MX (1) MXPA02009157A (de)
WO (1) WO2001070816A2 (de)

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US7563879B2 (en) 2001-09-26 2009-07-21 Intrexon Corporation Leafhopper ecdysone receptor nucleic acids, polypeptides, and uses thereof
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EP2699688A1 (de) 2011-04-20 2014-02-26 The Trustees Of The University Of Pennsylvania Dosierpläne und zusammensetzungen zur aav-vermittelten passiven immunisierung von luftbürtigen krankheitserregern
WO2014144380A1 (en) 2013-03-15 2014-09-18 Intrexon Corporation Boron-containing diacylhydrazines
US9719106B2 (en) 2013-04-29 2017-08-01 The Trustees Of The University Of Pennsylvania Tissue preferential codon modified expression cassettes, vectors containing same, and uses thereof
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CN103555727B (zh) * 2013-10-14 2015-06-10 中国水产科学研究院淡水渔业研究中心 一种中华绒螯蟹性早熟个体活体分子检测方法
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Also Published As

Publication number Publication date
EP1266015B1 (de) 2006-08-30
CA2404253A1 (en) 2001-09-27
AU2007200882A1 (en) 2007-03-22
CA2404253C (en) 2014-05-13
CN1422334A (zh) 2003-06-04
US7091038B2 (en) 2006-08-15
AU2007200882B2 (en) 2011-05-19
WO2001070816A3 (en) 2002-08-29
US20020119521A1 (en) 2002-08-29
DE60122685T2 (de) 2007-08-23
MXPA02009157A (es) 2004-04-05
AU2001249315A1 (en) 2001-10-03
JP2003527852A (ja) 2003-09-24
JP5031967B2 (ja) 2012-09-26
WO2001070816A2 (en) 2001-09-27
CN1304578C (zh) 2007-03-14
ATE338135T1 (de) 2006-09-15
AR028276A1 (es) 2003-04-30
EP1266015A2 (de) 2002-12-18

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Owner name: INTREXON CORP., BLACKBURG, VA., US