DE60106281T2 - Verfahren zur Behandlung eines Östrogenrezeptor-positiven Karzinoms - Google Patents
Verfahren zur Behandlung eines Östrogenrezeptor-positiven Karzinoms Download PDFInfo
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- DE60106281T2 DE60106281T2 DE60106281T DE60106281T DE60106281T2 DE 60106281 T2 DE60106281 T2 DE 60106281T2 DE 60106281 T DE60106281 T DE 60106281T DE 60106281 T DE60106281 T DE 60106281T DE 60106281 T2 DE60106281 T2 DE 60106281T2
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- Prior art keywords
- rapamycin
- carbon atoms
- antiestrogen
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Classifications
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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| US22432600P | 2000-08-11 | 2000-08-11 | |
| US224326P | 2000-08-11 | ||
| PCT/US2001/024615 WO2002013802A2 (en) | 2000-08-11 | 2001-08-06 | Method of treating estrogen receptor positive carcinoma |
Publications (2)
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| DE60106281D1 DE60106281D1 (de) | 2004-11-11 |
| DE60106281T2 true DE60106281T2 (de) | 2005-02-24 |
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| DE60106281T Expired - Fee Related DE60106281T2 (de) | 2000-08-11 | 2001-08-06 | Verfahren zur Behandlung eines Östrogenrezeptor-positiven Karzinoms |
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| US (1) | US6511986B2 (https=) |
| EP (1) | EP1318837B1 (https=) |
| JP (1) | JP2004507465A (https=) |
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| AT (1) | ATE278421T1 (https=) |
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| CA (1) | CA2416976C (https=) |
| DE (1) | DE60106281T2 (https=) |
| DK (1) | DK1318837T3 (https=) |
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| MX (1) | MXPA03001245A (https=) |
| PT (1) | PT1318837E (https=) |
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| US20100111928A1 (en) * | 1997-05-23 | 2010-05-06 | A & G Pharmaceutical, Inc. | Methods and kits for diagnosis tumorgenicity |
| US6881548B2 (en) * | 1997-05-23 | 2005-04-19 | A&G Pharmaceutical, Inc. | Methods and kits for diagnosing tumorigenicity and determining resistance to the antineoplastic effects of antiestrogen therapy |
| US20030215445A1 (en) * | 1997-05-23 | 2003-11-20 | Ginette Serrero | Methods and compositions for inhibiting the growth of hematopoietic malignant cells |
| US8512960B2 (en) * | 1997-05-23 | 2013-08-20 | A&G Pharmaceutical, Inc. | 88kDa tumorigenic growth factor and antagonists |
| US7091047B2 (en) * | 1997-05-23 | 2006-08-15 | A&G Pharmaceutical, Inc. | Methods and kits for diagnosing tumorigenicity |
| US6309826B1 (en) | 1997-05-23 | 2001-10-30 | Ginette Serrero | 88kDa tumorigenic growth factor and antagonists |
| US7617145B1 (en) * | 2000-10-24 | 2009-11-10 | Worldwide Farm Equipment Auctions.Com Ltd. | Adaptive bidding increments in an online auction system |
| TWI286074B (en) | 2000-11-15 | 2007-09-01 | Wyeth Corp | Pharmaceutical composition containing CCI-779 as an antineoplastic agent |
| AU2011226833B9 (en) * | 2001-02-19 | 2014-07-03 | Novartis Ag | Cancer treatment |
| PL409579A1 (pl) * | 2001-02-19 | 2015-03-02 | Novartis Ag | Leczenie raka |
| AU2016206379B2 (en) * | 2001-02-19 | 2017-09-14 | Novartis Ag | Cancer Treatment |
| EP1389209B1 (en) * | 2001-04-24 | 2009-04-08 | Purdue Research Foundation | Folate mimetics and folate-receptor binding conjugates thereof |
| PL211339B1 (pl) * | 2001-07-09 | 2012-05-31 | Zonagen | Zastosowanie kompozycji do wytwarzania leku do leczenia niedoboru testosteronu u samców ssaków |
| UA77200C2 (en) | 2001-08-07 | 2006-11-15 | Wyeth Corp | Antineoplastic combination of cci-779 and bkb-569 |
| JP4547911B2 (ja) | 2002-02-01 | 2010-09-22 | アリアド・ファーマシューティカルズ・インコーポレイテッド | リン含有化合物およびその用途 |
| WO2003097647A1 (en) * | 2002-05-15 | 2003-11-27 | Endocyte, Inc. | Vitamin-mitomycin conjugates |
| US7411045B2 (en) * | 2002-11-19 | 2008-08-12 | A&G Pharmaceutical, Inc. | Autocrine growth factor receptor antibodies and methods |
| DK1592457T3 (da) | 2003-01-27 | 2012-10-22 | Endocyte Inc | Folat-vinblastin-konjugat som lægemiddel |
| DE60334499D1 (de) * | 2003-02-26 | 2010-11-18 | A & G Pharmaceuticals Inc | Verfahren zur erhöhung der ausbreitung von b-zellen |
| UA83484C2 (uk) * | 2003-03-05 | 2008-07-25 | Уайт | Спосіб лікування раку грудей комбінацією похідного рапаміцину і інгібітора ароматази - летрозолу, фармацевтична композиція |
| ATE352301T1 (de) * | 2003-04-22 | 2007-02-15 | Wyeth Corp | Antineoplastische zusammensetzungen |
| KR20060070491A (ko) * | 2003-06-23 | 2006-06-23 | 에이 앤드 지 파마슈티컬즈, 인코포레이티드 | 항종양 요법에 대한 종양 세포의 감수성 회복 및 세포 사멸유도를 위한 조성물 및 방법 |
| CN1829514A (zh) * | 2003-07-25 | 2006-09-06 | 惠氏公司 | Cci－779冻干制剂 |
| JP2007517763A (ja) * | 2003-08-01 | 2007-07-05 | エイアンドジー ファーマスーティカル インコーポレイテッド | Ｈｅｒ２アンタゴニストを用いた治療への感受性を回復させる組成物および方法 |
| US7781478B2 (en) | 2004-07-14 | 2010-08-24 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
| JP5149620B2 (ja) | 2004-07-23 | 2013-02-20 | エンドサイト，インコーポレイテッド | ２価リンカーおよびその結合体 |
| KR20070070184A (ko) * | 2004-10-28 | 2007-07-03 | 와이어쓰 | 자궁근종의 치료에 있어서 ｍＴＯＲ 억제제의 용도 |
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-
2001
- 2001-08-06 JP JP2002518948A patent/JP2004507465A/ja not_active Withdrawn
- 2001-08-06 AT AT01961914T patent/ATE278421T1/de not_active IP Right Cessation
- 2001-08-06 WO PCT/US2001/024615 patent/WO2002013802A2/en not_active Ceased
- 2001-08-06 US US09/923,217 patent/US6511986B2/en not_active Expired - Fee Related
- 2001-08-06 ES ES01961914T patent/ES2228932T3/es not_active Expired - Lifetime
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- 2001-08-06 EP EP01961914A patent/EP1318837B1/en not_active Expired - Lifetime
- 2001-08-06 AU AU2001283139A patent/AU2001283139A1/en not_active Abandoned
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- 2001-08-06 CN CNB018137539A patent/CN100448487C/zh not_active Expired - Fee Related
- 2001-08-06 PT PT01961914T patent/PT1318837E/pt unknown
- 2001-08-06 DK DK01961914T patent/DK1318837T3/da active
- 2001-08-06 CA CA002416976A patent/CA2416976C/en not_active Expired - Fee Related
- 2001-08-10 AR ARP010103839A patent/AR033555A1/es unknown
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| HK1056687A1 (en) | 2004-02-27 |
| ES2228932T3 (es) | 2005-04-16 |
| DK1318837T3 (da) | 2005-01-10 |
| JP2004507465A (ja) | 2004-03-11 |
| WO2002013802A3 (en) | 2003-03-27 |
| CA2416976A1 (en) | 2002-02-21 |
| WO2002013802A2 (en) | 2002-02-21 |
| US20020045638A1 (en) | 2002-04-18 |
| CA2416976C (en) | 2008-05-20 |
| AU2001283139A1 (en) | 2002-02-25 |
| AR033555A1 (es) | 2003-12-26 |
| ATE278421T1 (de) | 2004-10-15 |
| US6511986B2 (en) | 2003-01-28 |
| DE60106281D1 (de) | 2004-11-11 |
| CN1446106A (zh) | 2003-10-01 |
| PT1318837E (pt) | 2004-12-31 |
| EP1318837B1 (en) | 2004-10-06 |
| EP1318837A2 (en) | 2003-06-18 |
| MXPA03001245A (es) | 2003-05-27 |
| CN100448487C (zh) | 2009-01-07 |
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