AU2001283139A1 - Method of treating estrogen receptor positive carcinoma - Google Patents
Method of treating estrogen receptor positive carcinomaInfo
- Publication number
- AU2001283139A1 AU2001283139A1 AU2001283139A AU8313901A AU2001283139A1 AU 2001283139 A1 AU2001283139 A1 AU 2001283139A1 AU 2001283139 A AU2001283139 A AU 2001283139A AU 8313901 A AU8313901 A AU 8313901A AU 2001283139 A1 AU2001283139 A1 AU 2001283139A1
- Authority
- AU
- Australia
- Prior art keywords
- estrogen receptor
- receptor positive
- treating estrogen
- positive carcinoma
- carcinoma
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22432600P | 2000-08-11 | 2000-08-11 | |
US60/224,326 | 2000-08-11 | ||
PCT/US2001/024615 WO2002013802A2 (en) | 2000-08-11 | 2001-08-06 | Method of treating estrogen receptor positive carcinoma |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001283139A1 true AU2001283139A1 (en) | 2002-02-25 |
Family
ID=22840171
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001283139A Abandoned AU2001283139A1 (en) | 2000-08-11 | 2001-08-06 | Method of treating estrogen receptor positive carcinoma |
Country Status (15)
Country | Link |
---|---|
US (1) | US6511986B2 (en) |
EP (1) | EP1318837B1 (en) |
JP (1) | JP2004507465A (en) |
CN (1) | CN100448487C (en) |
AR (1) | AR033555A1 (en) |
AT (1) | ATE278421T1 (en) |
AU (1) | AU2001283139A1 (en) |
CA (1) | CA2416976C (en) |
DE (1) | DE60106281T2 (en) |
DK (1) | DK1318837T3 (en) |
ES (1) | ES2228932T3 (en) |
HK (1) | HK1056687A1 (en) |
MX (1) | MXPA03001245A (en) |
PT (1) | PT1318837E (en) |
WO (1) | WO2002013802A2 (en) |
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US6309826B1 (en) * | 1997-05-23 | 2001-10-30 | Ginette Serrero | 88kDa tumorigenic growth factor and antagonists |
US8512960B2 (en) * | 1997-05-23 | 2013-08-20 | A&G Pharmaceutical, Inc. | 88kDa tumorigenic growth factor and antagonists |
US6881548B2 (en) * | 1997-05-23 | 2005-04-19 | A&G Pharmaceutical, Inc. | Methods and kits for diagnosing tumorigenicity and determining resistance to the antineoplastic effects of antiestrogen therapy |
US7091047B2 (en) * | 1997-05-23 | 2006-08-15 | A&G Pharmaceutical, Inc. | Methods and kits for diagnosing tumorigenicity |
US20030215445A1 (en) | 1997-05-23 | 2003-11-20 | Ginette Serrero | Methods and compositions for inhibiting the growth of hematopoietic malignant cells |
US6720159B1 (en) | 1997-12-16 | 2004-04-13 | A&G Pharmaceutical, Inc. | 88KDA tumorigenic growth factor and antagonists |
US20100111928A1 (en) * | 1997-05-23 | 2010-05-06 | A & G Pharmaceutical, Inc. | Methods and kits for diagnosis tumorgenicity |
US7617145B1 (en) * | 2000-10-24 | 2009-11-10 | Worldwide Farm Equipment Auctions.Com Ltd. | Adaptive bidding increments in an online auction system |
TWI286074B (en) | 2000-11-15 | 2007-09-01 | Wyeth Corp | Pharmaceutical composition containing CCI-779 as an antineoplastic agent |
AU2016206379B2 (en) * | 2001-02-19 | 2017-09-14 | Novartis Ag | Cancer Treatment |
PT3351246T (en) | 2001-02-19 | 2019-06-07 | Novartis Pharma Ag | Rapamycin derivative for the treatment of a solid tumor associated with deregulated angiogenesis |
AU2011226833B9 (en) * | 2001-02-19 | 2014-07-03 | Novartis Ag | Cancer treatment |
US7875612B2 (en) | 2001-04-24 | 2011-01-25 | Purdue Research Foundation | Folate mimetics and folate-receptor binding conjugates thereof |
PL211339B1 (en) * | 2001-07-09 | 2012-05-31 | Zonagen | Methods and materials for the treatment of testosterone deficiency in men |
UA77200C2 (en) | 2001-08-07 | 2006-11-15 | Wyeth Corp | Antineoplastic combination of cci-779 and bkb-569 |
AU2003210787B2 (en) | 2002-02-01 | 2009-04-23 | Medinol Ltd. | Phosphorus-containing compounds & uses thereof |
ATE426414T1 (en) * | 2002-05-15 | 2009-04-15 | Endocyte Inc | VITAMIN-MITOMYCIN CONJUGATES |
US7411045B2 (en) * | 2002-11-19 | 2008-08-12 | A&G Pharmaceutical, Inc. | Autocrine growth factor receptor antibodies and methods |
TWI367096B (en) | 2003-01-27 | 2012-07-01 | Endocyte Inc | Vitamin-receptor binding drug delivery conjugates and pharmaceutical compositions |
US7651854B2 (en) * | 2003-02-26 | 2010-01-26 | A & G Pharmaceutical, Inc. | Methods for increasing the proliferation of B cells |
UA83484C2 (en) * | 2003-03-05 | 2008-07-25 | Уайт | Method for treating breast cancer using combination of rapamycin derivative and aromatase inhibitor, pharmaceutical composition |
MXPA05010582A (en) * | 2003-04-22 | 2005-11-23 | Wyeth Corp | Antineoplastic combinations. |
JP2007524622A (en) * | 2003-06-23 | 2007-08-30 | エイアンドジー ファーマスーティカルズ インコーポレイテッド | Compositions and methods for restoring tumor cell sensitivity to anti-cancer therapy and inducing apoptosis |
BRPI0412916A (en) * | 2003-07-25 | 2006-09-26 | Wyeth Corp | lyophilized cci-779 formulations |
EP1660010B1 (en) * | 2003-08-01 | 2013-07-24 | A & G Pharmaceutical, Inc. | Compositions and methods for restoring sensitivity to treatment with her2 antagonists |
US7781478B2 (en) | 2004-07-14 | 2010-08-24 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
WO2006012527A1 (en) * | 2004-07-23 | 2006-02-02 | Endocyte, Inc. | Bivalent linkers and conjugates thereof |
EP1804779A1 (en) * | 2004-10-28 | 2007-07-11 | Wyeth | Use of an mtor inhibitor in treatment of uterine leiomyoma |
DE602006021142D1 (en) | 2005-02-03 | 2011-05-19 | Gen Hospital Corp | METHOD FOR THE TREATMENT OF GEFITINIB-RESISTANT CANCER |
JP2008533007A (en) | 2005-03-07 | 2008-08-21 | ワイス | Oxepane isomer of 42-O- (2-hydroxy) ethyl-rapamycin |
CN101175757B (en) * | 2005-03-16 | 2012-11-14 | 恩多塞特公司 | Synthesis and purification of pteroic acid and conjugates thereof |
RU2413508C2 (en) * | 2005-03-22 | 2011-03-10 | Репрос Терапьютикс Инк. | Trans-clomiphene dosing regimen |
US20080280937A1 (en) * | 2005-08-19 | 2008-11-13 | Christopher Paul Leamon | Ligand Conjugates of Vinca Alkaloids, Analogs, and Derivatives |
KR20130113543A (en) * | 2005-08-19 | 2013-10-15 | 엔도사이트, 인코포레이티드 | Multi-drug ligand conjugates |
CN103110948A (en) | 2005-11-04 | 2013-05-22 | 惠氏公司 | Antineoplastic combinations with mTOR inhibitor,herceptin, and/or HKI-272 |
DE102006011507A1 (en) * | 2006-03-14 | 2007-09-20 | Lts Lohmann Therapie-Systeme Ag | Active substance-loaded nanoparticles based on hydrophilic proteins |
WO2008101231A2 (en) * | 2007-02-16 | 2008-08-21 | Endocyte, Inc. | Methods and compositions for treating and diagnosing kidney disease |
EP2481427A1 (en) * | 2007-03-14 | 2012-08-01 | Endocyte, Inc. | Folate-Tubulysin conjugates |
RU2523909C2 (en) * | 2007-06-25 | 2014-07-27 | Эндосайт, Инк. | Conjugates, containing hydrophilic spacers of linkers |
US9877965B2 (en) | 2007-06-25 | 2018-01-30 | Endocyte, Inc. | Vitamin receptor drug delivery conjugates for treating inflammation |
US20090076060A1 (en) * | 2007-09-17 | 2009-03-19 | Protia, Llc | Deuterium-enriched temsirolimus |
UA96076C2 (en) * | 2007-10-16 | 2011-09-26 | Репрос Терапьютикс Инк. | Use of trans-clomiphene |
US8022216B2 (en) | 2007-10-17 | 2011-09-20 | Wyeth Llc | Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof |
US9187521B2 (en) | 2007-10-25 | 2015-11-17 | Endocyte, Inc. | Tubulysins and processes for preparing |
DK2656844T3 (en) | 2008-06-17 | 2015-03-02 | Wyeth Llc | ANTINEOPLASTIC COMBINATIONS CONTAINING HKI-272 AND VINORELBINE |
CN105963313A (en) | 2008-08-04 | 2016-09-28 | 惠氏有限责任公司 | Antineoplastic combinations of 4-anilino-3-cyanoquinolines and capecitabine |
AU2010234968B2 (en) | 2009-04-06 | 2015-05-14 | Wyeth Llc | Treatment regimen utilizing neratinib for breast cancer |
CA2800673A1 (en) | 2010-06-10 | 2011-12-15 | Aragon Pharmaceuticals, Inc. | Estrogen receptor modulators and uses thereof |
UA113291C2 (en) | 2011-08-04 | 2017-01-10 | TRANSCLOMYPHENE METABOLITES AND THEIR APPLICATIONS | |
US9187460B2 (en) | 2011-12-14 | 2015-11-17 | Seragon Pharmaceuticals, Inc. | Estrogen receptor modulators and uses thereof |
US10080805B2 (en) | 2012-02-24 | 2018-09-25 | Purdue Research Foundation | Cholecystokinin B receptor targeting for imaging and therapy |
US20140080175A1 (en) | 2012-03-29 | 2014-03-20 | Endocyte, Inc. | Processes for preparing tubulysin derivatives and conjugates thereof |
EA201590622A1 (en) | 2012-10-16 | 2015-10-30 | Эндосайт, Инк. | CONJUGATES FOR DELIVERY OF MEDICINES CONTAINING NOT MEETING IN THE NATURE OF AMINO ACID AND METHODS OF APPLICATION |
MX2015005160A (en) | 2012-11-02 | 2015-07-17 | Repros Therapeutics Inc | Trans-clomiphene for use in cancer therapy. |
RU2560708C1 (en) * | 2014-03-24 | 2015-08-20 | Федеральное государственное бюджетное учреждение "Научно-исследовательский институт клинической и экспериментальной лимфологии" Сибирского отделения Российской академии медицинских наук (ФГБУ "НИИКЭЛ" СО РАМН) | Method for differentiation stage-related hepatocarcinoma cells exposure to lithium nanopreparations |
HUE055321T2 (en) | 2015-10-01 | 2021-11-29 | Olema Pharmaceuticals Inc | Tetrahydro-1h-pyrido[3,4-b]indole anti-estrogenic drugs |
US10118910B2 (en) | 2015-12-09 | 2018-11-06 | The Board Of Trustees Of The University Of Illinois | Benzothiophene-based selective estrogen receptor downregulators |
CN109562113A (en) | 2016-05-10 | 2019-04-02 | C4医药公司 | Loop coil degron body for target protein degradation |
WO2017197055A1 (en) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | Heterocyclic degronimers for target protein degradation |
WO2017197046A1 (en) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | C3-carbon linked glutarimide degronimers for target protein degradation |
CN109789143A (en) | 2016-07-01 | 2019-05-21 | G1治疗公司 | Antiproliferative based on pyrimidine |
ES2909576T3 (en) | 2016-10-11 | 2022-05-09 | Univ Duke | Lasofoxifene treatment of ER+ breast cancer |
WO2018081168A2 (en) | 2016-10-24 | 2018-05-03 | The Board Of Trustees Of The University Of Illinois | Benzothiophene-based selective mixed estrogen receptor downregulators |
CN110177554B (en) | 2017-01-06 | 2023-06-02 | G1治疗公司 | Combination therapy for the treatment of cancer |
CN110461853A (en) | 2017-02-10 | 2019-11-15 | G1治疗公司 | Benzothiophene estrogenic agents |
CN110913861B (en) | 2017-06-29 | 2024-01-09 | G1治疗公司 | Morphological forms of G1T38 and methods of making the same |
CN112261937B (en) | 2018-04-10 | 2023-11-14 | 杜克大学 | Lasofoxifene treatment of breast cancer |
CN113453679A (en) | 2018-12-20 | 2021-09-28 | C4医药公司 | Targeted protein degradation |
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US4650803A (en) | 1985-12-06 | 1987-03-17 | University Of Kansas | Prodrugs of rapamycin |
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-
2001
- 2001-08-06 AU AU2001283139A patent/AU2001283139A1/en not_active Abandoned
- 2001-08-06 JP JP2002518948A patent/JP2004507465A/en not_active Withdrawn
- 2001-08-06 CA CA002416976A patent/CA2416976C/en not_active Expired - Fee Related
- 2001-08-06 US US09/923,217 patent/US6511986B2/en not_active Expired - Fee Related
- 2001-08-06 WO PCT/US2001/024615 patent/WO2002013802A2/en active IP Right Grant
- 2001-08-06 DE DE60106281T patent/DE60106281T2/en not_active Expired - Fee Related
- 2001-08-06 DK DK01961914T patent/DK1318837T3/en active
- 2001-08-06 CN CNB018137539A patent/CN100448487C/en not_active Expired - Fee Related
- 2001-08-06 PT PT01961914T patent/PT1318837E/en unknown
- 2001-08-06 MX MXPA03001245A patent/MXPA03001245A/en active IP Right Grant
- 2001-08-06 ES ES01961914T patent/ES2228932T3/en not_active Expired - Lifetime
- 2001-08-06 EP EP01961914A patent/EP1318837B1/en not_active Expired - Lifetime
- 2001-08-06 AT AT01961914T patent/ATE278421T1/en not_active IP Right Cessation
- 2001-08-10 AR ARP010103839A patent/AR033555A1/en unknown
-
2003
- 2003-12-12 HK HK03109077A patent/HK1056687A1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO2002013802A2 (en) | 2002-02-21 |
CA2416976A1 (en) | 2002-02-21 |
PT1318837E (en) | 2004-12-31 |
US20020045638A1 (en) | 2002-04-18 |
ES2228932T3 (en) | 2005-04-16 |
CA2416976C (en) | 2008-05-20 |
ATE278421T1 (en) | 2004-10-15 |
HK1056687A1 (en) | 2004-02-27 |
DE60106281D1 (en) | 2004-11-11 |
MXPA03001245A (en) | 2003-05-27 |
WO2002013802A3 (en) | 2003-03-27 |
EP1318837B1 (en) | 2004-10-06 |
DE60106281T2 (en) | 2005-02-24 |
AR033555A1 (en) | 2003-12-26 |
DK1318837T3 (en) | 2005-01-10 |
CN100448487C (en) | 2009-01-07 |
CN1446106A (en) | 2003-10-01 |
EP1318837A2 (en) | 2003-06-18 |
US6511986B2 (en) | 2003-01-28 |
JP2004507465A (en) | 2004-03-11 |
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