DE60037664D1 - Langkettige n-alkyl verbindungen und deren oxa-derivate zur verwendung als anitvirale mittel - Google Patents

Langkettige n-alkyl verbindungen und deren oxa-derivate zur verwendung als anitvirale mittel

Info

Publication number
DE60037664D1
DE60037664D1 DE60037664T DE60037664T DE60037664D1 DE 60037664 D1 DE60037664 D1 DE 60037664D1 DE 60037664 T DE60037664 T DE 60037664T DE 60037664 T DE60037664 T DE 60037664T DE 60037664 D1 DE60037664 D1 DE 60037664D1
Authority
DE
Germany
Prior art keywords
oxa
compounds
choice
long chain
low
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60037664T
Other languages
English (en)
Other versions
DE60037664T2 (de
Inventor
Nicole Zitzmann
Terry D Butters
Frances M Platt
Sandra Carrouee
Gary S Jacob
Donald H Picker
George Fleet
Raymond A Dwek
David Durantel
Anand Mehta
Timothy M Block
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Oxford
Thomas Jefferson University
Synergy Pharmaceuticals Inc
Original Assignee
University of Oxford
Thomas Jefferson University
Synergy Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Oxford, Thomas Jefferson University, Synergy Pharmaceuticals Inc filed Critical University of Oxford
Application granted granted Critical
Publication of DE60037664D1 publication Critical patent/DE60037664D1/de
Publication of DE60037664T2 publication Critical patent/DE60037664T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60037664T 1999-08-10 2000-08-10 Langkettige n-alkyl verbindungen und deren oxa-derivate zur verwendung als anitvirale mittel Expired - Lifetime DE60037664T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US14810199P 1999-08-10 1999-08-10
US148101P 1999-08-10
US19862100P 2000-04-20 2000-04-20
US198621P 2000-04-20
PCT/US2000/021732 WO2001010429A2 (en) 1999-08-10 2000-08-10 Long chain n-alkyl compounds and oxa-derivatives thereof and use as antiviral compositions

Publications (2)

Publication Number Publication Date
DE60037664D1 true DE60037664D1 (de) 2008-02-14
DE60037664T2 DE60037664T2 (de) 2008-12-24

Family

ID=26845521

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60037664T Expired - Lifetime DE60037664T2 (de) 1999-08-10 2000-08-10 Langkettige n-alkyl verbindungen und deren oxa-derivate zur verwendung als anitvirale mittel

Country Status (9)

Country Link
US (3) US7816560B1 (de)
EP (1) EP1210082B1 (de)
JP (1) JP2003506406A (de)
AT (1) ATE382351T1 (de)
AU (1) AU1840101A (de)
DE (1) DE60037664T2 (de)
ES (1) ES2302697T3 (de)
HK (1) HK1046869A1 (de)
WO (1) WO2001010429A2 (de)

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Also Published As

Publication number Publication date
AU1840101A (en) 2001-03-05
WO2001010429A3 (en) 2001-08-16
EP1210082A2 (de) 2002-06-05
WO2001010429A2 (en) 2001-02-15
DE60037664T2 (de) 2008-12-24
ES2302697T3 (es) 2008-08-01
US9089515B2 (en) 2015-07-28
EP1210082B1 (de) 2008-01-02
US20110184019A1 (en) 2011-07-28
JP2003506406A (ja) 2003-02-18
HK1046869A1 (zh) 2003-01-30
US7816560B1 (en) 2010-10-19
ATE382351T1 (de) 2008-01-15
US20100137365A1 (en) 2010-06-03

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