DE60034778T2 - Stoppen, schützen und konservieren von organen - Google Patents
Stoppen, schützen und konservieren von organen Download PDFInfo
- Publication number
- DE60034778T2 DE60034778T2 DE60034778T DE60034778T DE60034778T2 DE 60034778 T2 DE60034778 T2 DE 60034778T2 DE 60034778 T DE60034778 T DE 60034778T DE 60034778 T DE60034778 T DE 60034778T DE 60034778 T2 DE60034778 T2 DE 60034778T2
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- Prior art keywords
- adenosine
- solution
- composition according
- lignocaine
- heart
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- A61P9/06—Antiarrhythmics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/108331—Preservative, buffer, anticoagulant or diluent
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
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- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Dentistry (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPP9414A AUPP941499A0 (en) | 1999-03-23 | 1999-03-23 | Organ arrest, protection and preservation |
| AUPP941499 | 1999-03-23 | ||
| AUPQ4199A AUPQ419999A0 (en) | 1999-11-23 | 1999-11-23 | Organ arrest, protection and preservation |
| AUPQ419999 | 1999-11-23 | ||
| PCT/AU2000/000226 WO2000056145A1 (en) | 1999-03-23 | 2000-03-22 | Organ arrest, protection and preservation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60034778D1 DE60034778D1 (de) | 2007-06-21 |
| DE60034778T2 true DE60034778T2 (de) | 2008-01-31 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60034778T Expired - Lifetime DE60034778T2 (de) | 1999-03-23 | 2000-03-22 | Stoppen, schützen und konservieren von organen |
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| EP (3) | EP1790223A1 (enExample) |
| JP (1) | JP4949558B2 (enExample) |
| KR (1) | KR20020001797A (enExample) |
| CN (1) | CN1344135A (enExample) |
| AT (1) | ATE361667T1 (enExample) |
| BR (1) | BR0010653A (enExample) |
| CA (1) | CA2364687C (enExample) |
| DE (1) | DE60034778T2 (enExample) |
| ES (1) | ES2287001T3 (enExample) |
| IL (1) | IL145552A0 (enExample) |
| MX (1) | MXPA01009552A (enExample) |
| NO (2) | NO331669B1 (enExample) |
| NZ (1) | NZ514515A (enExample) |
| PL (1) | PL351484A1 (enExample) |
| TR (1) | TR200103235T2 (enExample) |
| WO (1) | WO2000056145A1 (enExample) |
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| IL145552A0 (en) | 1999-03-23 | 2002-06-30 | Univ James Cook | Organ arrest, protection and preservation |
| JP2005519928A (ja) | 2002-02-04 | 2005-07-07 | ハース，ベルナー | Ｃｏ放出能力を有する化合物の投与によって哺乳動物を治療する方法と、ｃｏ放出能力を有する化合物ならびにその医薬組成物 |
| AUPS312602A0 (en) * | 2002-06-21 | 2002-07-18 | James Cook University | Organ arrest, protection, preservation and recovery |
| US20040170950A1 (en) * | 2002-09-12 | 2004-09-02 | Prien Samuel D. | Organ preservation apparatus and methods |
| WO2004056180A1 (en) * | 2002-12-23 | 2004-07-08 | Global Cardiac Solutions Pty Ltd | Organ preconditioning, arrest, protection, preservation and recovery (1) |
| AU2003291847B2 (en) * | 2002-12-23 | 2010-12-02 | Hibernation Therapeutics, A Kf Llc | Organ preconditioning, arrest, protection, preservation and recovery |
| RU2008143202A (ru) * | 2006-03-31 | 2010-05-10 | Аденобио Н.В. (Nl) | Композиции, способы и наборы с использованием аденозина и инозина в комбинации для диагностики и лечения |
| CN104107431A (zh) * | 2006-05-29 | 2014-10-22 | 低温药理有限公司 | 改善的组织维持 |
| KR101425579B1 (ko) * | 2006-05-29 | 2014-08-13 | 하이버네이션 테라퓨틱스 리미티드 | 개선된 조직 유지법 |
| US7811549B2 (en) * | 2006-07-05 | 2010-10-12 | Adenobio N.V. | Methods, compositions, unit dosage forms, and kits for pharmacologic stress testing with reduced side effects |
| SG173404A1 (en) * | 2006-07-25 | 2011-08-29 | Hibernation Therapeutics Ltd | Trauma therapy |
| US20100119554A1 (en) * | 2007-03-02 | 2010-05-13 | Hibernation Therapeutics Limited | Transplants |
| WO2008134740A1 (en) * | 2007-04-30 | 2008-11-06 | The Trustees Of The University Of Pennsylvania | System and method of resuscitation of a mammal |
| KR20100081970A (ko) * | 2007-07-25 | 2010-07-15 | 하이버네이션 테라퓨틱스 리미티드 | 개선된 기관 보호, 보존 및 회복 |
| DE102007035642A1 (de) * | 2007-07-30 | 2009-02-12 | Grietje Beck | Substanzen zur Protektion von Zellen und Geweben gegen Schädigung durch ungünstige Bedingungen |
| WO2009092516A2 (en) * | 2008-01-22 | 2009-07-30 | Adenobio N.V. | Methods, compositions, unit dosage forms, and kits for pharmacologic stress testing with reduced side effects |
| US20120046354A1 (en) * | 2010-08-18 | 2012-02-23 | Ehrenpreis Eli D | Anti-oxidant lozenges for the prevention and treatment of radiation induced mucositis, precancerous lesions, oral cancer and other oral cavity mucosal disorders |
| ES2656237T3 (es) | 2011-04-19 | 2018-02-26 | Alfama, Inc. | Moléculas liberadoras de monóxido de carbono y usos de las mismas |
| EP2734235B1 (en) | 2011-07-21 | 2017-03-22 | Alfama, Inc. | Ruthenium carbon monoxide releasing molecules and uses thereof |
| US9381245B2 (en) | 2012-10-19 | 2016-07-05 | New York University | Methods for inhibiting osteolysis |
| WO2015006827A1 (en) | 2013-07-17 | 2015-01-22 | Hts Therapeutics Pty Ltd | A method for inducing whole body arrest |
| JP2013234200A (ja) * | 2013-08-19 | 2013-11-21 | Hibernation Therapeutics Ltd | 組織維持の改善 |
| US10092591B2 (en) | 2014-02-27 | 2018-10-09 | University Of Alaska Fairbanks | Methods and compositions for the treatment of ischemic injury to tissue using therapeutic hypothermia |
| CN103893205B (zh) * | 2014-04-15 | 2016-03-09 | 青岛大学附属医院 | 一种包含利多卡因和腺苷的心脏停搏液及其制备方法 |
| US20170049811A1 (en) * | 2014-05-01 | 2017-02-23 | Catherine E. Berry | Modified single dose, microplegic approach to cardioplegia for adult heart |
| US9501418B2 (en) * | 2014-06-26 | 2016-11-22 | HGST Netherlands B.V. | Invalidation data area for cache |
| US9913903B2 (en) * | 2015-08-06 | 2018-03-13 | Grifols Worldwide Operations Limited | Method for the treatment or prevention of infection-related immune conditions using a composition comprising IgM |
| CN109769797B (zh) * | 2017-11-13 | 2024-09-10 | 合肥华琪生物工程有限公司 | 一种器官保存液 |
| US12471592B2 (en) | 2021-08-18 | 2025-11-18 | Reelabs Private Limited | Cytoprotective compositions for short-term cells storage and transportation without cryopreservation and deep freezing |
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| SU878297A1 (ru) | 1978-05-03 | 1981-11-07 | Научно-Исследовательский Институт Трансплантологии И Искусственных Органов | Состав дл сохранени жизнеспособности оперируемого сердца |
| US4798824A (en) * | 1985-10-03 | 1989-01-17 | Wisconsin Alumni Research Foundation | Perfusate for the preservation of organs |
| US5006512A (en) | 1987-10-02 | 1991-04-09 | Tsuyoshi Ohnishi | Therapeutic usages of inhibitors for a potassium efflux channel |
| US5256770A (en) * | 1990-04-09 | 1993-10-26 | Schering Ag | Oxidation resistant thrombomodulin analogs |
| DE3926287A1 (de) * | 1989-08-09 | 1991-02-21 | Bernhard Clasbrummel | Medizinische anwendung von omega-conotoxin gvia oder omega-conotoxin gvia-analoga zur sympathikolyse |
| US5145771A (en) * | 1990-04-12 | 1992-09-08 | The University Of North Carolina At Chapel Hill | Rinse solution for organs and tissues |
| US5206222A (en) | 1991-05-22 | 1993-04-27 | Vanderbilt University | Methods for the reduction of myocardial reperfusion injury |
| CN1057192A (zh) | 1991-06-30 | 1991-12-25 | 汪庆富 | 风油精聚胺酯海绵的制备工艺 |
| US5407793A (en) | 1991-10-18 | 1995-04-18 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | An aqueous heart preservation and cardioplegia solution |
| RU2025973C1 (ru) | 1992-02-10 | 1995-01-09 | Научно-производственное предприятие "Биофарм" | Раствор для консервации живых органов |
| US5370989A (en) | 1992-04-03 | 1994-12-06 | The Trustees Of Columbia University In The City Of New York | Solution for prolonged organ preservation |
| US5405742A (en) * | 1993-07-16 | 1995-04-11 | Cyromedical Sciences, Inc. | Solutions for tissue preservation and bloodless surgery and methods using same |
| US5679706A (en) * | 1994-09-30 | 1997-10-21 | Bristol-Myers Squibb Company | Combination of a potassium channel activator and an antiarrhythmic agent |
| US5554497A (en) * | 1994-12-12 | 1996-09-10 | Charlotte-Mecklenburg Hospital Authority | Cardioplegic solution for arresting an organ |
| US5656420A (en) * | 1995-02-24 | 1997-08-12 | University Of Kentucky Research Foundation | Method for employing the delta opioid dadle to extend tissue survival time during ischemia |
| JP3875295B2 (ja) * | 1995-11-30 | 2007-01-31 | 功 竹内 | 心筋保護液 |
| CA2279651A1 (en) | 1996-09-05 | 1998-03-12 | Massachusetts Institute Of Technology | Compositions and methods for treatment of neurological disorders and neurodegenerative diseases |
| IT1297886B1 (it) | 1997-02-28 | 1999-12-20 | Carmine Antropoli | Nifedipina per uso topico |
| EP1014995A4 (en) | 1997-06-18 | 2005-02-16 | Aderis Pharmaceuticals Inc | COMPOSITIONS AND METHODS FOR PREVENTING RESTENOSES CONSECUTIVE TO REVASCULARIZATION INTERVENTIONS |
| CN1057192C (zh) | 1997-09-10 | 2000-10-11 | 上海长征医院 | 一种配制多器官保存液的方法 |
| US6011017A (en) | 1998-04-15 | 2000-01-04 | Cypros Pharmaceutical Corp. | Method of reducing pulmonary hypertension and atrial fibrillation after surgery using cardiopulmonary bypass |
| CA2336902C (en) | 1998-07-16 | 2009-04-21 | Memorial Sloan-Kettering Cancer Center | Topical compositions comprising an opioid analgesic and an nmda antagonist |
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| IL145552A0 (en) * | 1999-03-23 | 2002-06-30 | Univ James Cook | Organ arrest, protection and preservation |
| US6586413B2 (en) * | 1999-11-05 | 2003-07-01 | The United States Of America As Represented By The Department Of Health And Human Services | Methods and compositions for reducing ischemic injury of the heart by administering adenosine receptor agonists and antagonists |
| US20020006435A1 (en) | 2000-01-27 | 2002-01-17 | Samuels Paul J. | Transdermal anesthetic and vasodilator composition and methods for topical administration |
| JP2001261575A (ja) | 2000-03-13 | 2001-09-26 | General Hospital Corp | 血管収縮を調節する方法とその組成物 |
| US6569615B1 (en) | 2000-04-10 | 2003-05-27 | The United States Of America As Represented By The Department Of Veteran's Affairs | Composition and methods for tissue preservation |
| US6825203B2 (en) | 2000-04-28 | 2004-11-30 | Memorial Sloan-Kettering Cancer Center | Topical anesthetic/opioid formulations and uses thereof |
| ATE332668T1 (de) | 2000-09-26 | 2006-08-15 | Medtronic Inc | Medizinische vorrichtung zur blutstromsteuerung |
| GB0028414D0 (en) | 2000-11-22 | 2001-01-03 | Univ Leeds | Flush preservation solution |
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| ATE418991T1 (de) | 2002-04-18 | 2009-01-15 | Cv Therapeutics Inc | Methode zur behandlung von herzrhythmusstörungen mit einem a1 adenosin agonist zusammen mit einem beta blocker |
| AUPS312602A0 (en) | 2002-06-21 | 2002-07-18 | James Cook University | Organ arrest, protection, preservation and recovery |
| US20040229780A1 (en) * | 2002-09-20 | 2004-11-18 | Olivera Baldomero M. | KappaM-conopeptides as organ protectants |
| US6921633B2 (en) | 2002-11-18 | 2005-07-26 | Biolife Solutions Incorporated | Methods and compositions for the preservation of cells, tissues or organs in the vitreous state |
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| GB2436255B (en) | 2002-12-23 | 2007-11-28 | Global Cardiac Solutions Pty L | Organ preconditioning, arrest, protection, preservation and recovery |
| WO2004056180A1 (en) | 2002-12-23 | 2004-07-08 | Global Cardiac Solutions Pty Ltd | Organ preconditioning, arrest, protection, preservation and recovery (1) |
| US6992075B2 (en) | 2003-04-04 | 2006-01-31 | Barr Laboratories, Inc. | C(14) estrogenic compounds |
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| US7049309B2 (en) * | 2003-10-14 | 2006-05-23 | Bristol-Myers Squibb Company | 3-Thia-4-arylquinolin-2-one potassium channel modulators |
| EP1827298A4 (en) | 2004-12-22 | 2011-09-28 | Univ Emory | THERAPEUTIC APPARATUS FOR IMPROVING THE PROTECTIVE EFFECTS OF POST-CONDITIONING ORGANS |
| WO2007030198A2 (en) | 2005-07-11 | 2007-03-15 | Human Biosystems | Improved methods and solutions for storing donor organs |
| KR101425579B1 (ko) | 2006-05-29 | 2014-08-13 | 하이버네이션 테라퓨틱스 리미티드 | 개선된 조직 유지법 |
| SG173404A1 (en) | 2006-07-25 | 2011-08-29 | Hibernation Therapeutics Ltd | Trauma therapy |
| US20100119554A1 (en) | 2007-03-02 | 2010-05-13 | Hibernation Therapeutics Limited | Transplants |
| CN100423638C (zh) | 2007-03-22 | 2008-10-08 | 南京吉脉生物技术有限公司 | 一种器官保存液及其制备方法 |
| KR20100081970A (ko) | 2007-07-25 | 2010-07-15 | 하이버네이션 테라퓨틱스 리미티드 | 개선된 기관 보호, 보존 및 회복 |
-
2000
- 2000-03-22 IL IL14555200A patent/IL145552A0/xx unknown
- 2000-03-22 DE DE60034778T patent/DE60034778T2/de not_active Expired - Lifetime
- 2000-03-22 PL PL00351484A patent/PL351484A1/xx not_active Application Discontinuation
- 2000-03-22 CN CN00805408A patent/CN1344135A/zh active Pending
- 2000-03-22 EP EP06077320A patent/EP1790223A1/en not_active Withdrawn
- 2000-03-22 US US09/937,181 patent/US6955814B1/en not_active Expired - Lifetime
- 2000-03-22 CA CA2364687A patent/CA2364687C/en not_active Expired - Fee Related
- 2000-03-22 TR TR2001/03235T patent/TR200103235T2/xx unknown
- 2000-03-22 EP EP10181888.8A patent/EP2359688B1/en not_active Expired - Lifetime
- 2000-03-22 MX MXPA01009552A patent/MXPA01009552A/es unknown
- 2000-03-22 NZ NZ514515A patent/NZ514515A/en not_active IP Right Cessation
- 2000-03-22 WO PCT/AU2000/000226 patent/WO2000056145A1/en not_active Ceased
- 2000-03-22 EP EP00910414A patent/EP1168912B1/en not_active Expired - Lifetime
- 2000-03-22 KR KR1020017012071A patent/KR20020001797A/ko not_active Withdrawn
- 2000-03-22 BR BR0010653-4A patent/BR0010653A/pt not_active Application Discontinuation
- 2000-03-22 AT AT00910414T patent/ATE361667T1/de not_active IP Right Cessation
- 2000-03-22 ES ES00910414T patent/ES2287001T3/es not_active Expired - Lifetime
- 2000-03-22 JP JP2000606063A patent/JP4949558B2/ja not_active Expired - Fee Related
-
2001
- 2001-09-19 NO NO20014557A patent/NO331669B1/no not_active IP Right Cessation
-
2005
- 2005-02-01 US US11/046,866 patent/US7223413B2/en not_active Expired - Fee Related
-
2007
- 2007-04-24 US US11/790,216 patent/US20070270372A1/en not_active Abandoned
-
2009
- 2009-08-13 US US12/541,000 patent/US7749522B2/en not_active Expired - Fee Related
-
2010
- 2010-05-27 US US12/788,864 patent/US20100298254A1/en not_active Abandoned
-
2011
- 2011-06-03 NO NO20110807A patent/NO20110807L/no not_active Application Discontinuation
-
2013
- 2013-03-05 US US13/786,041 patent/US9320753B2/en not_active Expired - Fee Related
-
2016
- 2016-03-18 US US15/074,471 patent/US20160263141A1/en not_active Abandoned
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