DE60032940T2 - Neue verfahren und zubereitungen die opioiden und deren antagonisten enthalten - Google Patents
Neue verfahren und zubereitungen die opioiden und deren antagonisten enthalten Download PDFInfo
- Publication number
- DE60032940T2 DE60032940T2 DE60032940T DE60032940T DE60032940T2 DE 60032940 T2 DE60032940 T2 DE 60032940T2 DE 60032940 T DE60032940 T DE 60032940T DE 60032940 T DE60032940 T DE 60032940T DE 60032940 T2 DE60032940 T2 DE 60032940T2
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- Prior art keywords
- opioid
- compound
- compounds
- formula
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45080699A | 1999-11-29 | 1999-11-29 | |
| US450806 | 1999-11-29 | ||
| PCT/US2000/042315 WO2001037785A2 (en) | 1999-11-29 | 2000-11-29 | Novel methods and compositions involving opioids and antagonists thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60032940D1 DE60032940D1 (de) | 2007-02-22 |
| DE60032940T2 true DE60032940T2 (de) | 2007-11-08 |
Family
ID=23789563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60032940T Expired - Lifetime DE60032940T2 (de) | 1999-11-29 | 2000-11-29 | Neue verfahren und zubereitungen die opioiden und deren antagonisten enthalten |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1244447B1 (enExample) |
| JP (1) | JP2003528819A (enExample) |
| AU (1) | AU784541B2 (enExample) |
| CA (1) | CA2392362A1 (enExample) |
| CY (1) | CY1106359T1 (enExample) |
| DE (1) | DE60032940T2 (enExample) |
| DK (1) | DK1244447T3 (enExample) |
| ES (1) | ES2278647T3 (enExample) |
| IL (2) | IL149600A0 (enExample) |
| MX (1) | MXPA02005335A (enExample) |
| NZ (1) | NZ518562A (enExample) |
| PT (1) | PT1244447E (enExample) |
| WO (1) | WO2001037785A2 (enExample) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6274591B1 (en) | 1997-11-03 | 2001-08-14 | Joseph F. Foss | Use of methylnaltrexone and related compounds |
| HU226730B1 (en) | 1997-12-22 | 2009-08-28 | Euro Celtique Sa | Pharmaceutical oral dosage form comprising a combination of an opioid agonist and naltrextone |
| CN101703777B (zh) | 2000-02-08 | 2012-11-28 | 欧罗赛铁克股份有限公司 | 抗破坏口服阿片样激动剂 |
| DE60238756D1 (de) | 2001-05-11 | 2011-02-10 | Endo Pharmaceuticals Inc | Opioid enthaltende arzneiform gegen missbrauch |
| EP1404323B1 (en) * | 2001-06-05 | 2009-10-28 | The University of Chicago | Use of methylnaltrexone to treat immune suppression |
| MXPA04000584A (es) | 2001-07-18 | 2004-04-20 | Euro Celtique Sa | COMBINACIONES FARMACeUTICAS DE OXICODONA Y NALOXONA. |
| US7914818B2 (en) | 2001-08-06 | 2011-03-29 | Purdue Pharma L.P. | Opioid agonist formulations with releasable and sequestered antagonist |
| US20030157168A1 (en) | 2001-08-06 | 2003-08-21 | Christopher Breder | Sequestered antagonist formulations |
| RU2295344C2 (ru) | 2002-04-05 | 2007-03-20 | Еуро-Селтик С.А. | Фармацевтический препарат, содержащий оксикодон и налоксон |
| EP2422772A3 (en) | 2002-09-20 | 2012-04-18 | Alpharma, Inc. | Sequestering subunit and related compositions and methods |
| ES2528631T3 (es) | 2003-04-08 | 2015-02-11 | Progenics Pharmaceuticals, Inc. | Formulaciones farmacéuticas que contienen metilnaltrexona |
| TWI347201B (en) | 2003-04-21 | 2011-08-21 | Euro Celtique Sa | Pharmaceutical products,uses thereof and methods for preparing the same |
| US6992090B2 (en) * | 2003-06-16 | 2006-01-31 | Adolor Corporation | Substituted piperidine compounds and methods of their use |
| US7700626B2 (en) | 2004-06-04 | 2010-04-20 | Adolor Corporation | Compositions containing opioid antagonists |
| US20090069363A1 (en) * | 2004-12-14 | 2009-03-12 | Shionogi & Co. Ltd. A Legal Entity Of Japan | Therapeutic Agent for Constipation |
| EP1702558A1 (en) | 2005-02-28 | 2006-09-20 | Euro-Celtique S.A. | Method and device for the assessment of bowel function |
| US20060211733A1 (en) * | 2005-03-04 | 2006-09-21 | Adolor Corporation | Methods of preventing and treating opioid bowel dysfunction |
| US9662325B2 (en) | 2005-03-07 | 2017-05-30 | The University Of Chicago | Use of opioid antagonists to attenuate endothelial cell proliferation and migration |
| US8524731B2 (en) | 2005-03-07 | 2013-09-03 | The University Of Chicago | Use of opioid antagonists to attenuate endothelial cell proliferation and migration |
| US8518962B2 (en) | 2005-03-07 | 2013-08-27 | The University Of Chicago | Use of opioid antagonists |
| CN101171010B (zh) | 2005-03-07 | 2014-09-17 | 芝加哥大学 | 阿片样物质拮抗剂用于减少内皮细胞增殖和迁移的用途 |
| AR057035A1 (es) | 2005-05-25 | 2007-11-14 | Progenics Pharm Inc | SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS |
| AR057325A1 (es) | 2005-05-25 | 2007-11-28 | Progenics Pharm Inc | Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos |
| WO2006126529A1 (ja) | 2005-05-25 | 2006-11-30 | Shionogi & Co., Ltd. | ６，７－不飽和－７－カルバモイル置換モルヒナン誘導体 |
| EP1762569A1 (en) * | 2005-09-12 | 2007-03-14 | Alcasynn Pharmaceuticals Gmbh | Novel 6-amino-morphinan derivatives, method of manufacturing them and their application as analgesics |
| WO2007121916A2 (en) | 2006-04-21 | 2007-11-01 | Dsm Ip Assets B.V. | Use of opioid receptor antagonists |
| KR20150029762A (ko) | 2006-06-19 | 2015-03-18 | 알파마 파머슈티컬스 엘엘씨 | 약제학적 조성물 |
| TWI489984B (zh) | 2006-08-04 | 2015-07-01 | Wyeth Corp | 用於非經腸道傳輸化合物之配方及其用途 |
| ES2765811T5 (es) | 2007-03-29 | 2024-02-27 | Progenics Pharm Inc | Forma cristalina de bromuro de (R)-n-metilnaltrexona y sus usos |
| PL2565195T3 (pl) | 2007-03-29 | 2015-10-30 | Wyeth Llc | Obwodowy receptor opioidowy i jego antagoniści oraz ich zastosowania |
| WO2008121348A2 (en) | 2007-03-29 | 2008-10-09 | Progenics Pharmaceuticals, Inc. | Peripheral opioid receptor antagonists and uses thereof |
| US8263807B2 (en) | 2007-08-09 | 2012-09-11 | Rensselaer Polytechnic Institute | Quaternary opioid carboxamides |
| JP5905198B2 (ja) * | 2007-10-01 | 2016-04-20 | ザ ユニヴァーシティー オヴ シカゴ | 薬剤誘発性吐き気のオピオイド拮抗薬による治療 |
| AU2008331235C1 (en) * | 2007-11-30 | 2013-01-17 | Purdue Pharma L.P. | Benzomorphan Compounds |
| US8623418B2 (en) | 2007-12-17 | 2014-01-07 | Alpharma Pharmaceuticals Llc | Pharmaceutical composition |
| EP2730578A1 (en) | 2008-02-06 | 2014-05-14 | Progenics Pharmaceuticals, Inc. | Preparation and use of (r),(r)-2,2'-bis-methylnal trexone |
| AU2009225434B2 (en) | 2008-03-21 | 2014-05-22 | The University Of Chicago | Treatment with opioid antagonists and mTOR inhibitors |
| CA2676881C (en) | 2008-09-30 | 2017-04-25 | Wyeth | Peripheral opioid receptor antagonists and uses thereof |
| JP5886632B2 (ja) | 2009-03-10 | 2016-03-16 | ユーロ−セルティーク エス．エイ． | オキシコドンおよびナロキソンを含む即時放出医薬組成物 |
| HRP20191029T1 (hr) | 2009-12-04 | 2019-09-20 | Alkermes Pharma Ireland Limited | Derivati morfinana radi liječenja predoziranja lijekom |
| EP2550253B9 (en) | 2010-03-22 | 2016-09-21 | Rensselaer Polytechnic Institute | Morphinane derivatives containing a carboxamide group as opioid receptor ligands |
| HUE065427T2 (hu) | 2010-08-23 | 2024-05-28 | Alkermes Pharma Ireland Ltd | Eljárások antipszichotikum által indukált súlygyarapodás kezelésére |
| PL2725908T3 (pl) | 2011-06-29 | 2017-10-31 | Alkermes Inc | Działające obwodowo związki opioidowe |
| US9211293B2 (en) | 2011-12-15 | 2015-12-15 | Alkermes Pharma Ireland Limited | Opioid agonist antagonist combinations |
| WO2014172482A1 (en) * | 2013-04-17 | 2014-10-23 | Robert Alfred Volkmann | Compounds for treatment of pain |
| US10072018B2 (en) | 2013-04-17 | 2018-09-11 | Biopharma Works | Compounds for treatment of pain |
| NZ716267A (en) | 2013-07-23 | 2017-05-26 | Euro Celtique Sa | A combination of oxycodone and naloxone for use in treating pain in patients suffering from pain and a disease resulting in intestinal dysbiosis and/or increasing the risk for intestinal bacterial translocation |
| KR102201609B1 (ko) | 2019-04-19 | 2021-01-12 | 연성정밀화학(주) | 날데메딘의 제조방법 |
| WO2022101444A1 (en) | 2020-11-12 | 2022-05-19 | Alkermes Pharma Ireland Limited | Immediate release multilayer tablet |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4457933A (en) * | 1980-01-24 | 1984-07-03 | Bristol-Myers Company | Prevention of analgesic abuse |
| GB8332556D0 (en) * | 1983-12-06 | 1984-01-11 | Reckitt & Colmann Prod Ltd | Analgesic compositions |
| US4769372A (en) * | 1986-06-18 | 1988-09-06 | The Rockefeller University | Method of treating patients suffering from chronic pain or chronic cough |
| ES2058265T3 (es) * | 1987-04-16 | 1994-11-01 | Lilly Co Eli | Piperidinas antagonistas de opiaceos. |
| US5250542A (en) * | 1991-03-29 | 1993-10-05 | Eli Lilly And Company | Peripherally selective piperidine carboxylate opioid antagonists |
-
2000
- 2000-11-29 DK DK00992256T patent/DK1244447T3/da active
- 2000-11-29 CA CA002392362A patent/CA2392362A1/en not_active Abandoned
- 2000-11-29 ES ES00992256T patent/ES2278647T3/es not_active Expired - Lifetime
- 2000-11-29 IL IL14960000A patent/IL149600A0/xx unknown
- 2000-11-29 WO PCT/US2000/042315 patent/WO2001037785A2/en not_active Ceased
- 2000-11-29 NZ NZ518562A patent/NZ518562A/en unknown
- 2000-11-29 DE DE60032940T patent/DE60032940T2/de not_active Expired - Lifetime
- 2000-11-29 AU AU39706/01A patent/AU784541B2/en not_active Ceased
- 2000-11-29 JP JP2001539402A patent/JP2003528819A/ja active Pending
- 2000-11-29 EP EP00992256A patent/EP1244447B1/en not_active Expired - Lifetime
- 2000-11-29 MX MXPA02005335A patent/MXPA02005335A/es active IP Right Grant
- 2000-11-29 PT PT00992256T patent/PT1244447E/pt unknown
-
2002
- 2002-05-12 IL IL149600A patent/IL149600A/en not_active IP Right Cessation
-
2007
- 2007-03-07 CY CY20071100318T patent/CY1106359T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001037785A2 (en) | 2001-05-31 |
| WO2001037785A3 (en) | 2002-01-10 |
| CY1106359T1 (el) | 2011-10-12 |
| EP1244447A4 (en) | 2003-06-04 |
| DK1244447T3 (da) | 2007-04-23 |
| AU3970601A (en) | 2001-06-04 |
| EP1244447A2 (en) | 2002-10-02 |
| IL149600A0 (en) | 2002-11-10 |
| MXPA02005335A (es) | 2003-01-28 |
| IL149600A (en) | 2010-06-16 |
| WO2001037785A9 (en) | 2002-08-29 |
| EP1244447B1 (en) | 2007-01-10 |
| CA2392362A1 (en) | 2001-05-31 |
| ES2278647T3 (es) | 2007-08-16 |
| AU784541B2 (en) | 2006-04-27 |
| NZ518562A (en) | 2005-04-29 |
| JP2003528819A (ja) | 2003-09-30 |
| PT1244447E (pt) | 2007-02-28 |
| DE60032940D1 (de) | 2007-02-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8328 | Change in the person/name/address of the agent |
Representative=s name: DRAUDT, A., DIPL.-ING., PAT.-ANW., 42289 WUPPERTAL |
|
| 8364 | No opposition during term of opposition |