DE60001736T2 - 1-trifluorotmethyl-4-hydroxy-7-piperidinyl-aminomethylchroman-derivate - Google Patents

1-trifluorotmethyl-4-hydroxy-7-piperidinyl-aminomethylchroman-derivate

Info

Publication number
DE60001736T2
DE60001736T2 DE60001736T DE60001736T DE60001736T2 DE 60001736 T2 DE60001736 T2 DE 60001736T2 DE 60001736 T DE60001736 T DE 60001736T DE 60001736 T DE60001736 T DE 60001736T DE 60001736 T2 DE60001736 T2 DE 60001736T2
Authority
DE
Germany
Prior art keywords
disorders
disorder
compound
alkyl
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60001736T
Other languages
German (de)
English (en)
Other versions
DE60001736D1 (de
Inventor
Scott Obach
Alan Scully
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Pfizer Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Application granted granted Critical
Publication of DE60001736D1 publication Critical patent/DE60001736D1/de
Publication of DE60001736T2 publication Critical patent/DE60001736T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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DE60001736T 1999-05-21 2000-04-20 1-trifluorotmethyl-4-hydroxy-7-piperidinyl-aminomethylchroman-derivate Expired - Fee Related DE60001736T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13539999P 1999-05-21 1999-05-21
PCT/IB2000/000493 WO2000071538A2 (en) 1999-05-21 2000-04-20 1-trifluoromethyl-4-hydroxy-7-piperidinyl-aminomethylchroman derivatives

Publications (2)

Publication Number Publication Date
DE60001736D1 DE60001736D1 (de) 2003-04-24
DE60001736T2 true DE60001736T2 (de) 2003-09-18

Family

ID=22467939

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60001736T Expired - Fee Related DE60001736T2 (de) 1999-05-21 2000-04-20 1-trifluorotmethyl-4-hydroxy-7-piperidinyl-aminomethylchroman-derivate

Country Status (49)

Country Link
US (1) US6239147B1 (ru)
EP (1) EP1178984B1 (ru)
JP (1) JP3802762B2 (ru)
KR (1) KR100453301B1 (ru)
CN (1) CN1140525C (ru)
AP (1) AP1396A (ru)
AR (1) AR020294A1 (ru)
AT (1) ATE234832T1 (ru)
AU (1) AU775861B2 (ru)
BG (1) BG106152A (ru)
BR (1) BR0011284A (ru)
CA (1) CA2374643C (ru)
CO (1) CO5170464A1 (ru)
CR (1) CR6503A (ru)
CZ (1) CZ20014164A3 (ru)
DE (1) DE60001736T2 (ru)
DK (1) DK1178984T3 (ru)
DZ (1) DZ3044A1 (ru)
EA (1) EA004233B1 (ru)
EE (1) EE04719B1 (ru)
ES (1) ES2190781T3 (ru)
GC (1) GC0000254A (ru)
GE (1) GEP20043225B (ru)
GT (1) GT200000073A (ru)
HK (1) HK1046280B (ru)
HN (1) HN2000000057A (ru)
HR (1) HRP20010861A2 (ru)
HU (1) HUP0201443A3 (ru)
IL (1) IL145949A0 (ru)
IS (1) IS6123A (ru)
MA (1) MA26734A1 (ru)
MX (1) MXPA01011977A (ru)
MY (1) MY123373A (ru)
NO (1) NO322496B1 (ru)
NZ (1) NZ514698A (ru)
OA (1) OA11944A (ru)
PA (1) PA8495201A1 (ru)
PE (1) PE20010165A1 (ru)
PL (1) PL198658B1 (ru)
PT (1) PT1178984E (ru)
SK (1) SK285819B6 (ru)
SV (1) SV2002000077A (ru)
TN (1) TNSN00105A1 (ru)
TR (1) TR200103332T2 (ru)
TW (1) TWI275588B (ru)
UA (1) UA71004C2 (ru)
UY (1) UY26147A1 (ru)
WO (1) WO2000071538A2 (ru)
ZA (1) ZA200109554B (ru)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW426667B (en) * 1997-11-19 2001-03-21 Pfizer Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists
ATE257477T1 (de) * 1999-10-18 2004-01-15 Pfizer Prod Inc Verfahren zur herstellung von zyklischen piperidinylaminomethyl-trifluoromethyl- etherderivaten
DE10311984A1 (de) * 2003-03-12 2004-09-23 Freie Universität Berlin Verwendung von NEP-assoziierten Molekülen zur Behandlung von nichtimmunogenen-nichthypertensiven Zivilisationskrankheiten
US7122700B2 (en) * 2004-07-30 2006-10-17 Xerox Corporation Arylamine processes
US7868016B2 (en) * 2005-07-13 2011-01-11 Baxter International Inc. Pharmaceutical formulations of endo-N-(9-methyl-9-azabicyclo[3,3.1]non-3-yl)-1-methyl-1H-indazole-3-carboxamide hydrochloride
WO2009109001A1 (en) * 2008-03-04 2009-09-11 Adelaide Research & Innovation Pty Ltd Method for preventing and/or treating a disease, condition or state associated with reduced dopaminergic neuron function
DK2307397T3 (da) 2008-06-25 2014-11-03 Array Biopharma Inc 6-substituerede phenoxychroman-carboxylsyrederivater
CN117343036A (zh) * 2023-03-20 2024-01-05 江苏联环药业股份有限公司 异苯并二氢吡喃类化合物及其药物组合物和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY110227A (en) * 1991-08-12 1998-03-31 Ciba Geigy Ag 1-acylpiperindine compounds.
GB9317987D0 (en) * 1993-08-26 1993-10-13 Glaxo Group Ltd Chemical compounds
WO1996030367A1 (fr) * 1995-03-27 1996-10-03 Hisamitsu Pharmaceutical Co., Inc. Derives de piperidine
RU2156250C2 (ru) * 1995-04-24 2000-09-20 Новартис Аг Производные хромона, способ их получения и фармацевтическая композиция
ATE199552T1 (de) * 1995-07-07 2001-03-15 Pfizer Substituierte benzolaktamverbindungen als substanz-p-antagonisten
TW340842B (en) * 1995-08-24 1998-09-21 Pfizer Substituted benzylaminopiperidine compounds
TW426667B (en) * 1997-11-19 2001-03-21 Pfizer Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists

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HUP0201443A2 (en) 2002-08-28
EA200101109A1 (ru) 2002-04-25
TR200103332T2 (tr) 2002-04-22
CO5170464A1 (es) 2002-06-27
HUP0201443A3 (en) 2005-09-28
HRP20010861A2 (en) 2003-04-30
EE04719B1 (et) 2006-10-16
EP1178984A2 (en) 2002-02-13
MY123373A (en) 2006-05-31
PE20010165A1 (es) 2001-02-20
EP1178984B1 (en) 2003-03-19
OA11944A (en) 2006-04-12
IL145949A0 (en) 2002-07-25
JP2003500405A (ja) 2003-01-07
MXPA01011977A (es) 2002-05-06
GC0000254A (en) 2006-11-01
HK1046280B (zh) 2004-10-21
SK285819B6 (sk) 2007-09-06
NO322496B1 (no) 2006-10-16
TNSN00105A1 (fr) 2005-11-10
AU3667300A (en) 2000-12-12
BG106152A (en) 2002-06-28
KR100453301B1 (ko) 2004-10-20
IS6123A (is) 2001-10-23
CZ20014164A3 (cs) 2003-01-15
PL352409A1 (en) 2003-08-25
ES2190781T3 (es) 2003-08-16
KR20020016793A (ko) 2002-03-06
PA8495201A1 (es) 2002-08-26
EE200100612A (et) 2003-02-17
ZA200109554B (en) 2002-11-20
HK1046280A1 (en) 2003-01-03
UY26147A1 (es) 2000-12-29
HN2000000057A (es) 2001-03-02
CN1355799A (zh) 2002-06-26
NO20015652L (no) 2002-01-14
CR6503A (es) 2004-02-03
SK16592001A3 (sk) 2003-03-04
TWI275588B (en) 2007-03-11
AR020294A1 (es) 2002-05-02
DZ3044A1 (fr) 2004-03-27
MA26734A1 (fr) 2004-12-20
WO2000071538A3 (en) 2001-02-22
SV2002000077A (es) 2002-07-03
GEP20043225B (en) 2004-04-26
WO2000071538A2 (en) 2000-11-30
PT1178984E (pt) 2003-06-30
EA004233B1 (ru) 2004-02-26
NO20015652D0 (no) 2001-11-20
PL198658B1 (pl) 2008-07-31
BR0011284A (pt) 2002-03-05
GT200000073A (es) 2001-11-09
AP1396A (en) 2005-04-19
US6239147B1 (en) 2001-05-29
DK1178984T3 (da) 2003-06-10
DE60001736D1 (de) 2003-04-24
CA2374643A1 (en) 2000-11-30
AP2001002327A0 (en) 2001-12-31
AU775861B2 (en) 2004-08-19
NZ514698A (en) 2005-01-28
UA71004C2 (ru) 2004-11-15
JP3802762B2 (ja) 2006-07-26
CA2374643C (en) 2006-02-14
ATE234832T1 (de) 2003-04-15
CN1140525C (zh) 2004-03-03

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