GT200000073A - Derivados de 1-trifluorometil- 4-hidroxi- 7-piperidinil-aminometilcromano. - Google Patents

Derivados de 1-trifluorometil- 4-hidroxi- 7-piperidinil-aminometilcromano.

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Publication number
GT200000073A
GT200000073A GT200000073A GT200000073A GT200000073A GT 200000073 A GT200000073 A GT 200000073A GT 200000073 A GT200000073 A GT 200000073A GT 200000073 A GT200000073 A GT 200000073A GT 200000073 A GT200000073 A GT 200000073A
Authority
GT
Guatemala
Prior art keywords
companies
signed
emesis
derivatives
aminometilcromano
Prior art date
Application number
GT200000073A
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English (en)
Inventor
Ronald Scott Obach
Douglas Allan Scully
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Filing date
Publication date
Application filed filed Critical
Publication of GT200000073A publication Critical patent/GT200000073A/es

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    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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Abstract

ESTA INVENCION SE REFIERE A NUEVOS DERIVADOS DEL COMPUESTO SEÑALADO EN EL TITULO PROPORCIONA COMPUESTOS ETER CICLICOS DE PIPERIDINILAMINOTILTRIFLUOROMETILO, CUYA FORMULA ESTRUCTURAL ESTA SEÑALADA COMO FORMULA I, SE REFIERE TAMBIEN A SUS SALES FARMACEUTICAMENTE ACEPTABLES, A COMPOSICIONES QUE CONTIENEN DICHOS COMPUESTOS Y AL USO DE DICHOS COMPUESTOS COMO SUSTANCIAS ANTAGONISTAS DE LA SUSTANCIA P, LA CUAL SE HALLA IMPLICADA EN LA TRANSMISION DEL DOLOR, EN TRASTORNOS DEL SISTEMA NERVIOSO CENTRAL, EN ENFERMEDADES INFLAMATORIAS Y RESPIRATORIAS. LOS COMPUESTOS DE LA PRESENTE INVENCION SON PARTICULARMENTE UTILES PARA EL TRATAMIENTO DE LA EMESIS, INCLUYENDO EMESIS AGUDA, RETRASADA O ANTICIPADA Y LA INDUCIDA POR AGENTES ANTINEOPLASTICOS, INCLUYENDO AQUELLOS UTILIZADOS EN TERAPIA DE CANCER.
GT200000073A 1999-05-21 2000-05-18 Derivados de 1-trifluorometil- 4-hidroxi- 7-piperidinil-aminometilcromano. GT200000073A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13539999P 1999-05-21 1999-05-21

Publications (1)

Publication Number Publication Date
GT200000073A true GT200000073A (es) 2001-11-09

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ID=22467939

Family Applications (1)

Application Number Title Priority Date Filing Date
GT200000073A GT200000073A (es) 1999-05-21 2000-05-18 Derivados de 1-trifluorometil- 4-hidroxi- 7-piperidinil-aminometilcromano.

Country Status (49)

Country Link
US (1) US6239147B1 (es)
EP (1) EP1178984B1 (es)
JP (1) JP3802762B2 (es)
KR (1) KR100453301B1 (es)
CN (1) CN1140525C (es)
AP (1) AP1396A (es)
AR (1) AR020294A1 (es)
AT (1) ATE234832T1 (es)
AU (1) AU775861B2 (es)
BG (1) BG106152A (es)
BR (1) BR0011284A (es)
CA (1) CA2374643C (es)
CO (1) CO5170464A1 (es)
CR (1) CR6503A (es)
CZ (1) CZ20014164A3 (es)
DE (1) DE60001736T2 (es)
DK (1) DK1178984T3 (es)
DZ (1) DZ3044A1 (es)
EA (1) EA004233B1 (es)
EE (1) EE04719B1 (es)
ES (1) ES2190781T3 (es)
GC (1) GC0000254A (es)
GE (1) GEP20043225B (es)
GT (1) GT200000073A (es)
HK (1) HK1046280B (es)
HN (1) HN2000000057A (es)
HR (1) HRP20010861A2 (es)
HU (1) HUP0201443A3 (es)
IL (1) IL145949A0 (es)
IS (1) IS6123A (es)
MA (1) MA26734A1 (es)
MX (1) MXPA01011977A (es)
MY (1) MY123373A (es)
NO (1) NO322496B1 (es)
NZ (1) NZ514698A (es)
OA (1) OA11944A (es)
PA (1) PA8495201A1 (es)
PE (1) PE20010165A1 (es)
PL (1) PL198658B1 (es)
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Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW426667B (en) * 1997-11-19 2001-03-21 Pfizer Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists
ES2211455T3 (es) * 1999-10-18 2004-07-16 Pfizer Products Inc. Procedimiento para la preparacion de compuestos eteres ciclicos piperidinilaminometil trifluorometilicos.
DE10311984A1 (de) * 2003-03-12 2004-09-23 Freie Universität Berlin Verwendung von NEP-assoziierten Molekülen zur Behandlung von nichtimmunogenen-nichthypertensiven Zivilisationskrankheiten
US7122700B2 (en) * 2004-07-30 2006-10-17 Xerox Corporation Arylamine processes
US7868016B2 (en) * 2005-07-13 2011-01-11 Baxter International Inc. Pharmaceutical formulations of endo-N-(9-methyl-9-azabicyclo[3,3.1]non-3-yl)-1-methyl-1H-indazole-3-carboxamide hydrochloride
WO2009109001A1 (en) * 2008-03-04 2009-09-11 Adelaide Research & Innovation Pty Ltd Method for preventing and/or treating a disease, condition or state associated with reduced dopaminergic neuron function
RS53665B1 (en) 2008-06-25 2015-04-30 Array Biopharma Inc. 6-SUBSTITUTED CARBOXYLIC ACID PHENOXYCHROME DERIVATIVES

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY110227A (en) * 1991-08-12 1998-03-31 Ciba Geigy Ag 1-acylpiperindine compounds.
GB9317987D0 (en) * 1993-08-26 1993-10-13 Glaxo Group Ltd Chemical compounds
KR19980703354A (ko) * 1995-03-27 1998-10-15 나카토미히로타카 피페리딘 유도체
RU2156250C2 (ru) * 1995-04-24 2000-09-20 Новартис Аг Производные хромона, способ их получения и фармацевтическая композиция
WO1997003066A1 (en) * 1995-07-07 1997-01-30 Pfizer Pharmaceuticals Inc. Substituted benzolactam compounds as substance p antagonists
TW340842B (en) * 1995-08-24 1998-09-21 Pfizer Substituted benzylaminopiperidine compounds
TW426667B (en) * 1997-11-19 2001-03-21 Pfizer Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists

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CN1355799A (zh) 2002-06-26
DK1178984T3 (da) 2003-06-10
JP2003500405A (ja) 2003-01-07
MXPA01011977A (es) 2002-05-06
PA8495201A1 (es) 2002-08-26
UY26147A1 (es) 2000-12-29
AU775861B2 (en) 2004-08-19
DE60001736T2 (de) 2003-09-18
HUP0201443A2 (en) 2002-08-28
PE20010165A1 (es) 2001-02-20
WO2000071538A2 (en) 2000-11-30
HN2000000057A (es) 2001-03-02
OA11944A (en) 2006-04-12
ZA200109554B (en) 2002-11-20
EE200100612A (et) 2003-02-17
NO20015652D0 (no) 2001-11-20
JP3802762B2 (ja) 2006-07-26
MA26734A1 (fr) 2004-12-20
IL145949A0 (en) 2002-07-25
UA71004C2 (uk) 2004-11-15
HUP0201443A3 (en) 2005-09-28
AU3667300A (en) 2000-12-12
KR100453301B1 (ko) 2004-10-20
IS6123A (is) 2001-10-23
TWI275588B (en) 2007-03-11
GC0000254A (en) 2006-11-01
HRP20010861A2 (en) 2003-04-30
AR020294A1 (es) 2002-05-02
ATE234832T1 (de) 2003-04-15
CO5170464A1 (es) 2002-06-27
TNSN00105A1 (fr) 2005-11-10
EE04719B1 (et) 2006-10-16
BR0011284A (pt) 2002-03-05
EP1178984B1 (en) 2003-03-19
BG106152A (en) 2002-06-28
TR200103332T2 (tr) 2002-04-22
DZ3044A1 (fr) 2004-03-27
CA2374643C (en) 2006-02-14
WO2000071538A3 (en) 2001-02-22
KR20020016793A (ko) 2002-03-06
HK1046280A1 (en) 2003-01-03
EA004233B1 (ru) 2004-02-26
NO322496B1 (no) 2006-10-16
SK285819B6 (sk) 2007-09-06
GEP20043225B (en) 2004-04-26
SK16592001A3 (sk) 2003-03-04
EP1178984A2 (en) 2002-02-13
PL198658B1 (pl) 2008-07-31
SV2002000077A (es) 2002-07-03
DE60001736D1 (de) 2003-04-24
CN1140525C (zh) 2004-03-03
CR6503A (es) 2004-02-03
CZ20014164A3 (cs) 2003-01-15
AP2001002327A0 (en) 2001-12-31
ES2190781T3 (es) 2003-08-16
PT1178984E (pt) 2003-06-30
MY123373A (en) 2006-05-31
PL352409A1 (en) 2003-08-25
EA200101109A1 (ru) 2002-04-25
AP1396A (en) 2005-04-19
US6239147B1 (en) 2001-05-29
CA2374643A1 (en) 2000-11-30
NO20015652L (no) 2002-01-14
NZ514698A (en) 2005-01-28
HK1046280B (zh) 2004-10-21

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